CN102001940B - 一种贲亭酸甲酯的连续化合成方法 - Google Patents
一种贲亭酸甲酯的连续化合成方法 Download PDFInfo
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- CN102001940B CN102001940B CN 201010616879 CN201010616879A CN102001940B CN 102001940 B CN102001940 B CN 102001940B CN 201010616879 CN201010616879 CN 201010616879 CN 201010616879 A CN201010616879 A CN 201010616879A CN 102001940 B CN102001940 B CN 102001940B
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- dimethyl
- synthetic method
- tower
- steps
- trimethyl orthoacetate
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- 238000001308 synthesis method Methods 0.000 title abstract 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 title 1
- MKLKDUHMZCIBSJ-UHFFFAOYSA-N methyl 3,3-dimethylpent-4-enoate Chemical compound COC(=O)CC(C)(C)C=C MKLKDUHMZCIBSJ-UHFFFAOYSA-N 0.000 claims abstract description 35
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims abstract description 33
- HDPNBNXLBDFELL-UHFFFAOYSA-N 1,1,1-trimethoxyethane Chemical compound COC(C)(OC)OC HDPNBNXLBDFELL-UHFFFAOYSA-N 0.000 claims abstract description 30
- 239000007788 liquid Substances 0.000 claims abstract description 23
- 239000000047 product Substances 0.000 claims abstract description 14
- 239000006227 byproduct Substances 0.000 claims abstract description 13
- 238000006243 chemical reaction Methods 0.000 claims abstract description 10
- 238000000034 method Methods 0.000 claims abstract description 9
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims description 28
- ASUAYTHWZCLXAN-UHFFFAOYSA-N prenol Chemical compound CC(C)=CCO ASUAYTHWZCLXAN-UHFFFAOYSA-N 0.000 claims description 17
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims description 14
- 238000010189 synthetic method Methods 0.000 claims description 13
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 claims description 12
- 239000000945 filler Substances 0.000 claims description 7
- 238000000926 separation method Methods 0.000 claims description 7
- 235000019260 propionic acid Nutrition 0.000 claims description 6
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 claims description 6
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims description 4
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 claims description 3
- 238000003786 synthesis reaction Methods 0.000 abstract description 7
- 230000015572 biosynthetic process Effects 0.000 abstract description 6
- 239000003054 catalyst Substances 0.000 abstract 1
- 238000011031 large-scale manufacturing process Methods 0.000 abstract 1
- 230000036632 reaction speed Effects 0.000 abstract 1
- 241000282326 Felis catus Species 0.000 description 8
- 238000004587 chromatography analysis Methods 0.000 description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 239000000575 pesticide Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- HIXDQWDOVZUNNA-UHFFFAOYSA-N 2-(3,4-dimethoxyphenyl)-5-hydroxy-7-methoxychromen-4-one Chemical compound C=1C(OC)=CC(O)=C(C(C=2)=O)C=1OC=2C1=CC=C(OC)C(OC)=C1 HIXDQWDOVZUNNA-UHFFFAOYSA-N 0.000 description 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000003905 agrochemical Substances 0.000 description 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 description 1
- 229910052794 bromium Inorganic materials 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 150000004702 methyl esters Chemical class 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 238000004886 process control Methods 0.000 description 1
- 239000002728 pyrethroid Substances 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
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- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Description
Claims (10)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN 201010616879 CN102001940B (zh) | 2010-12-31 | 2010-12-31 | 一种贲亭酸甲酯的连续化合成方法 |
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CN 201010616879 CN102001940B (zh) | 2010-12-31 | 2010-12-31 | 一种贲亭酸甲酯的连续化合成方法 |
Publications (2)
Publication Number | Publication Date |
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CN102001940A CN102001940A (zh) | 2011-04-06 |
CN102001940B true CN102001940B (zh) | 2013-07-24 |
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CN 201010616879 Active CN102001940B (zh) | 2010-12-31 | 2010-12-31 | 一种贲亭酸甲酯的连续化合成方法 |
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Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102557934A (zh) * | 2012-01-17 | 2012-07-11 | 山东高新润农化学有限公司 | 一种贲亭酸甲酯的连续化合成方法 |
CN105541620A (zh) * | 2015-12-16 | 2016-05-04 | 绍兴明业化纤有限公司 | 一种贲亭酸甲酯的生产方法 |
CN114409532B (zh) * | 2022-02-10 | 2023-06-30 | 山东新和成维生素有限公司 | 一种贲亭酸甲酯的连续化合成方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0041343A1 (en) * | 1980-06-02 | 1981-12-09 | Ici Australia Limited | A process for the synthesis of gamma-unsaturated carboxylic acid esters |
CN1907947A (zh) * | 2006-08-09 | 2007-02-07 | 淄博万昌科技发展有限公司 | 工业规模制备贲亭酸甲酯的方法 |
-
2010
- 2010-12-31 CN CN 201010616879 patent/CN102001940B/zh active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0041343A1 (en) * | 1980-06-02 | 1981-12-09 | Ici Australia Limited | A process for the synthesis of gamma-unsaturated carboxylic acid esters |
CN1907947A (zh) * | 2006-08-09 | 2007-02-07 | 淄博万昌科技发展有限公司 | 工业规模制备贲亭酸甲酯的方法 |
Non-Patent Citations (3)
Title |
---|
罗先金.化工设计.《化工设计》.中国纺织出版社,2007,(第1版),第121、122、137、109页. * |
贲亭酸甲酯的合成研究;邹军等;《农药》;19960925;第35卷(第9期);第9页第2栏第3-6行 * |
邹军等.贲亭酸甲酯的合成研究.《农药》.1996,第35卷(第9期),第8,9,20页. |
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CN102001940A (zh) | 2011-04-06 |
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