CN101990547A - Il-23受体拮抗剂以及其应用 - Google Patents

Il-23受体拮抗剂以及其应用 Download PDF

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CN101990547A
CN101990547A CN2008800236017A CN200880023601A CN101990547A CN 101990547 A CN101990547 A CN 101990547A CN 2008800236017 A CN2008800236017 A CN 2008800236017A CN 200880023601 A CN200880023601 A CN 200880023601A CN 101990547 A CN101990547 A CN 101990547A
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西尔万·谢姆托比
克里斯蒂安·基尼乌
威廉·D·卢贝尔
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CN2008800236017A 2007-07-06 2008-07-07 Il-23受体拮抗剂以及其应用 Pending CN101990547A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US95866007P 2007-07-06 2007-07-06
US60/958,660 2007-07-06
PCT/IB2008/002490 WO2009007849A2 (en) 2007-07-06 2008-07-07 Il-23 receptor antagonists and uses thereof

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CN101990547A true CN101990547A (zh) 2011-03-23

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CN2008800236017A Pending CN101990547A (zh) 2007-07-06 2008-07-07 Il-23受体拮抗剂以及其应用

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US (1) US20100190710A1 (https=)
EP (1) EP2288621A4 (https=)
JP (1) JP2011501941A (https=)
CN (1) CN101990547A (https=)
AU (1) AU2008273814A1 (https=)
CA (1) CA2692037A1 (https=)
IL (1) IL202752A0 (https=)
WO (1) WO2009007849A2 (https=)

Cited By (4)

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Publication number Priority date Publication date Assignee Title
CN108348580A (zh) * 2015-07-15 2018-07-31 领导医疗有限公司 白细胞介素-23受体的肽抑制剂以及其治疗炎症性疾病的用途
CN108618100A (zh) * 2018-05-10 2018-10-09 广东天企生物科技有限公司 一种具有鲜味和增鲜特性的四肽及其用途
CN116082455A (zh) * 2019-07-10 2023-05-09 领导医疗有限公司 白细胞介素-23受体的肽抑制剂及其用于治疗炎症性疾病的用途
WO2026067838A1 (zh) * 2024-09-30 2026-04-02 上海瀚辰星泰医药科技有限公司 一种多肽化合物及其应用

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US8946150B2 (en) 2011-06-14 2015-02-03 Medical Diagnostic Laboratories, LLC. Polypeptides that bound to IL-23 receptor and inhibit binding of IL-23 and cell signaling thereof
US9605027B2 (en) * 2011-06-14 2017-03-28 Medical Diagnostic Laboratories, Llc Polypeptides that bound to IL-23 receptor and inhibit binding of IL-23 and cell signaling thereof
USRE49026E1 (en) * 2011-06-14 2022-04-12 Medical Diagnostic Laboratories, Llc Polypeptides that bound to IL-23 receptor and inhibit binding of IL-23 and cell signaling thereof
US20140221648A1 (en) * 2011-06-27 2014-08-07 Galderma Research & Developement Th17 differentiation markers for acne and uses thereof
CN107012201A (zh) 2011-06-27 2017-08-04 高德美研究及发展公司 用于痤疮的新th17分化标志物及其用途
US9273093B2 (en) 2012-10-11 2016-03-01 Protagonist Therapeutics, Inc. α4β7 peptide dimer antagonists
CZ304514B6 (cs) * 2012-11-23 2014-06-11 Biotechnologický Ústav Av Čr, V.V.I. Polypeptidy pro léčbu autoimunitních chorob založenou na blokaci receptoru pro lidský cytokin IL-23
DK2968443T3 (da) 2013-03-15 2021-12-06 Protagonist Therapeutics Inc Hepcidinanaloger og anvendelser deraf
PT3143037T (pt) 2014-05-16 2021-09-24 Protagonist Therapeutics Inc Antagonistas peptídicos tioéter de integrina alfa4beta7
US9624268B2 (en) 2014-07-17 2017-04-18 Protagonist Therapeutics, Inc. Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseases
EP3201217A4 (en) 2014-10-01 2018-07-18 Protagonist Therapeutics Inc. Novel cyclic monomer and dimer peptides having integrin antagonist activity
KR20170108936A (ko) 2014-10-01 2017-09-27 프로타고니스트 테라퓨틱스, 인코포레이티드 신규한 α4β7 펩타이드 단량체 및 이량체 길항제
US10787490B2 (en) 2015-07-15 2020-09-29 Protaganist Therapeutics, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
US20190002503A1 (en) 2015-12-30 2019-01-03 Protagonist Therapeutics, Inc. Analogues of hepcidin mimetics with improved in vivo half lives
WO2017165676A1 (en) 2016-03-23 2017-09-28 Protagonist Therapeutics, Inc. METHODS FOR SYNTHESIZING α4β7 PEPTIDE ANTAGONISTS
US20190270786A1 (en) * 2016-07-27 2019-09-05 Protagonist Therapeutics, Inc. Peptide inhibitors of interleukin-23 and their use to treat inflammatory diseases
EP3681900A4 (en) 2017-09-11 2021-09-08 Protagonist Therapeutics, Inc. OPIOID AGONIST PEPTIDES AND THEIR USES
EP3749345A4 (en) 2018-02-08 2022-04-06 Protagonist Therapeutics, Inc. CONJUGATED HEPCIDIN MIMETICS
TW202019948A (zh) 2018-07-12 2020-06-01 美商領導醫療有限公司 介白素-23受體之肽抑制劑及其治療發炎疾病之用途
HRP20250769T1 (hr) 2020-01-15 2025-08-29 Janssen Biotech, Inc. Peptidni inhibitori receptora za interleukin-23 i njihova uporaba u liječenju upalnih bolesti
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