CN101972270B - External powder for preventing and curing dermatophytosis - Google Patents
External powder for preventing and curing dermatophytosis Download PDFInfo
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- CN101972270B CN101972270B CN2010105361879A CN201010536187A CN101972270B CN 101972270 B CN101972270 B CN 101972270B CN 2010105361879 A CN2010105361879 A CN 2010105361879A CN 201010536187 A CN201010536187 A CN 201010536187A CN 101972270 B CN101972270 B CN 101972270B
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- 239000000843 powder Substances 0.000 title claims abstract description 18
- 206010012504 Dermatophytosis Diseases 0.000 title abstract 4
- 241001460074 Microsporum distortum Species 0.000 title abstract 4
- 208000002474 Tinea Diseases 0.000 title abstract 4
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 claims abstract description 20
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims abstract description 12
- 239000002994 raw material Substances 0.000 claims abstract description 11
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims abstract description 10
- 229960004889 salicylic acid Drugs 0.000 claims abstract description 10
- 239000005711 Benzoic acid Substances 0.000 claims abstract description 9
- ZOIORXHNWRGPMV-UHFFFAOYSA-N acetic acid;zinc Chemical compound [Zn].CC(O)=O.CC(O)=O ZOIORXHNWRGPMV-UHFFFAOYSA-N 0.000 claims abstract description 9
- 235000010233 benzoic acid Nutrition 0.000 claims abstract description 9
- 239000004246 zinc acetate Substances 0.000 claims abstract description 9
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 claims abstract description 8
- 229960001763 zinc sulfate Drugs 0.000 claims abstract description 8
- 229910000368 zinc sulfate Inorganic materials 0.000 claims abstract description 8
- 206010047601 Vitamin B1 deficiency Diseases 0.000 claims description 14
- 208000002894 beriberi Diseases 0.000 claims description 14
- 238000010298 pulverizing process Methods 0.000 claims description 7
- 238000003756 stirring Methods 0.000 claims description 7
- 238000005303 weighing Methods 0.000 claims description 6
- 239000002253 acid Substances 0.000 claims description 4
- 238000012360 testing method Methods 0.000 abstract description 12
- 238000002791 soaking Methods 0.000 abstract description 3
- 229960004365 benzoic acid Drugs 0.000 abstract 1
- 235000009508 confectionery Nutrition 0.000 abstract 1
- 229960000314 zinc acetate Drugs 0.000 abstract 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 24
- 210000003491 skin Anatomy 0.000 description 23
- 239000007788 liquid Substances 0.000 description 18
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 16
- 230000035617 depilation Effects 0.000 description 15
- 239000000463 material Substances 0.000 description 12
- 230000000694 effects Effects 0.000 description 9
- 229910052697 platinum Inorganic materials 0.000 description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 8
- 241000700199 Cavia porcellus Species 0.000 description 7
- 206010015150 Erythema Diseases 0.000 description 7
- WXBLLCUINBKULX-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1.OC(=O)C1=CC=CC=C1 WXBLLCUINBKULX-UHFFFAOYSA-N 0.000 description 7
- 239000003814 drug Substances 0.000 description 7
- 210000002615 epidermis Anatomy 0.000 description 7
- 239000000203 mixture Substances 0.000 description 7
- 239000000047 product Substances 0.000 description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- 208000008454 Hyperhidrosis Diseases 0.000 description 6
- 206010070834 Sensitisation Diseases 0.000 description 6
- 230000037396 body weight Effects 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 238000012545 processing Methods 0.000 description 6
- 239000011265 semifinished product Substances 0.000 description 6
- 230000008313 sensitization Effects 0.000 description 6
- 208000013460 sweaty Diseases 0.000 description 6
- 201000004624 Dermatitis Diseases 0.000 description 5
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- 239000002390 adhesive tape Substances 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 210000004209 hair Anatomy 0.000 description 4
- 206010030113 Oedema Diseases 0.000 description 3
- 206010040880 Skin irritation Diseases 0.000 description 3
- 206010058679 Skin oedema Diseases 0.000 description 3
- 238000010171 animal model Methods 0.000 description 3
- 231100000321 erythema Toxicity 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 230000002265 prevention Effects 0.000 description 3
- 238000011084 recovery Methods 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 210000003169 central nervous system Anatomy 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 239000003651 drinking water Substances 0.000 description 2
- 235000020188 drinking water Nutrition 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 210000001508 eye Anatomy 0.000 description 2
- 239000004744 fabric Substances 0.000 description 2
- 210000003746 feather Anatomy 0.000 description 2
- 230000007794 irritation Effects 0.000 description 2
- 206010025482 malaise Diseases 0.000 description 2
- 210000004877 mucosa Anatomy 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 230000029058 respiratory gaseous exchange Effects 0.000 description 2
- 231100000475 skin irritation Toxicity 0.000 description 2
- 230000036556 skin irritation Effects 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 229910052979 sodium sulfide Inorganic materials 0.000 description 2
- GRVFOGOEDUUMBP-UHFFFAOYSA-N sodium sulfide (anhydrous) Chemical compound [Na+].[Na+].[S-2] GRVFOGOEDUUMBP-UHFFFAOYSA-N 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 230000002269 spontaneous effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- VHBSECWYEFJRNV-UHFFFAOYSA-N 2-hydroxybenzoic acid Chemical compound OC(=O)C1=CC=CC=C1O.OC(=O)C1=CC=CC=C1O VHBSECWYEFJRNV-UHFFFAOYSA-N 0.000 description 1
- 241000700198 Cavia Species 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 206010017533 Fungal infection Diseases 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 208000031888 Mycoses Diseases 0.000 description 1
- 241000219784 Sophora Species 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 231100000215 acute (single dose) toxicity testing Toxicity 0.000 description 1
- 238000011047 acute toxicity test Methods 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000001166 anti-perspirative effect Effects 0.000 description 1
- 239000003213 antiperspirant Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 238000004332 deodorization Methods 0.000 description 1
- 229910003460 diamond Inorganic materials 0.000 description 1
- 239000010432 diamond Substances 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 230000002497 edematous effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- XLYOFNOQVPJJNP-ZSJDYOACSA-N heavy water Substances [2H]O[2H] XLYOFNOQVPJJNP-ZSJDYOACSA-N 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 230000001338 necrotic effect Effects 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
- 238000011076 safety test Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 210000000106 sweat gland Anatomy 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- 210000002268 wool Anatomy 0.000 description 1
- RZLVQBNCHSJZPX-UHFFFAOYSA-L zinc sulfate heptahydrate Chemical compound O.O.O.O.O.O.O.[Zn+2].[O-]S([O-])(=O)=O RZLVQBNCHSJZPX-UHFFFAOYSA-L 0.000 description 1
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention provides external powder for preventing and curing dermatophytosis, which is prepared from zinc acetate, benzoic acid, salicylic acid, zinc sulfate and the like used as raw materials. The powder has the efficacies of preventing and curing dermatophytosis, foot sweet and foot odor. The clinic test statistic result shows that the total efficiency accounts for 96.87 percent, and the powder can be used for lavipeditum or foot-gear soaking for preventing and curing dermatophytosis.
Description
Technical field
The present invention relates to a kind of externally-applied powder of preventing and treating beriberi.
Background technology
Improving constantly of Along with people's living standard; Pursuing high-grade life style has become a kind of fashion, and beriberi, sweaty foot, foot odor are the common skin diseases that is caused by fungal infection, and general summer, sickness rate was high; Winter, sickness rate was low; Be prone to recurrence, groups of people are not healed throughout the year, and it is perplexing people's productive life.At present, the medicine of this persistent ailment of common treatment has ZUGUANG SAN, Compound Flavescent Sophora and Salicylic Acid Powder etc., although these medicines all have curative effect in various degree to beriberi, sweaty foot, foot odor patient, prevention effect is not too obvious.
Summary of the invention
The purpose of this invention is to provide a kind of externally-applied powder that can effectively prevent and treat beriberi, sweaty foot, foot odor, to overcome the defective that prior art exists.
The object of the invention is realized through following measure, and a kind of externally-applied powder of preventing and treating beriberi comprises the raw material of following ratio of quality and the number of copies:
Zinc acetate 12-15 benzoic acid 10-13 salicylic acid 9-12 zinc sulfate 5-8
Above-mentioned externally-applied powder, can select to form by the raw material of following ratio of quality and the number of copies:
Zinc acetate 15 benzoic acid 13 salicylic acid 9 zinc sulfate 8
Prevent and treat the beriberi externally-applied powder and take following processing step production:
A. prepare burden: the raw material according to above ratio of quality and the number of copies is formed weighing, puts into the acid-resistant container of getting ready and stirs, and makes its mix homogeneously as far as possible.
B. pulverize: the material of mix homogeneously is poured in the pulverizer pulverized, temperature is at 10-110 ℃ during pulverizing, and the size of pulverizing is controlled at about 100 orders.
C. stirred gong: the material that will crush stirs, and carries out the gong processing then and is the semi-finished product material.
D. fill: utilize filling machine that the semi-finished product material is packed in quantitative pouch or the bottle, close mouth and seal, add outer package and be product.
Just formed a kind of excellent solvent after zinc acetate [(CH3COO) 2Zn.2H2O] is water-soluble, to promote the dissolvings in water such as benzoic acid, salicylic acid; Zinc sulfate (ZnSO4.7H2O) has the effect of convergence sweat gland; Benzoic acid (benzoic acid) mainly plays the inhibition fungus and grows and drive smelly; Salicylic acid (salicylic acid) mainly plays the effect of removing the necrotic tissue meat.Owing to added zinc acetate, improved dissolubility, impel organic acid such as benzoic acid, salicylic acid water-soluble as early as possible, promoted the usefulness of said composition greatly, antibacterial, antibacterial, deodorization, go the antiperspirant effect more obvious.
During use, get product 5 pouches of the present invention, pour in the container that fills 2500 milliliters of eliminating cold for resuscitation water and dissolve, promptly process this solution, use this solution soaking foot 10-15 minute, can prevent and treat beriberi, sweaty foot, foot odor; Or get product 1 pouch of the present invention, and pour in the container that fills 500 milliliters of eliminating cold for resuscitation water and dissolve, use this solution soaking footgear 1-2 minute, can drive away the abnormal flavour of footgear.
The present invention's (name of product of the present invention is " a sufficient platinum ") shows that through following three cutaneous safeties test it belongs to safe external used medicine:
Receive trial product: get " sufficient platinum " powder (specification 5 gram/bags, lot number 20090615, plastic bag packaging) pouch, pour in the container of the distilled water that fills 500 milliliters and dissolve, be mixed with " sufficient platinum " solution.Usage and consumption: solution is dipped on absorbent cotton, rub injured affected part (in following three safety tests, we abbreviate " sufficient platinum " solution as " medicinal liquid ").
Toxicity test: this experiment selected rabbit is observed the toxic reaction that after giving with medicinal liquid on the complete and damaged depilation skin of rabbit, is produced for 3 times on the one as experimental animal.Get 8 of healthy rabbits, 24h before the test, every tame rabbit back both sides are first with the about 150cm of curved scissors QUMAO
2, lose hair or feathers with 8% sodium sulfide solution again.Be divided into 2 groups of (4 every group), i.e. intact skin group and damaged skin groups at random.Behind the depilation 24h, take by weighing rabbit body weight and record (initial body weight).Rabbit is fixed in the fixed mount, and intact skin group rabbit is only embrocated medicinal liquid on the depilation epidermis by 6ml/, and with non-stimulated gauze, immobilization with adhesive tape; Damaged skin group rabbit depilation epidermis is used 75% ethanol disinfection earlier, and the capable network-like cut of reuse aseptic syringe needle is to spend to oozing of blood, embrocate on cut oozing of blood depilation epidermis by 6ml/ medicinal liquid immediately, and with non-stimulated husky cloth, immobilization with adhesive tape.Send two groups of rabbit back to cage position separately after the administration, feed and drinking-water affranchise.Whenever embrocated 1 time, embrocate continuously 3 times at a distance from 4 hours.After 24 hours with warm water flush away medicinal liquid, so that observe.Observe and the situation of record administration 1,24,48,72 hours and 4,5,6,7 days rabbit skin, hair, eyes, mucosa, body weight, and the variation of breathing, circulation, central nervous system, extremity activity etc.3 medications on the one of intact skin group and damaged skin group rabbit were observed 7 days continuously, and damaged skin was spontaneous recovery after 24 hours; Two groups of rabbit depilation skins are not all seen skin erythema, edema, and hair, eyes, mucosa and breathing, circulation, central nervous system, extremity activity are all normal.The result shows: after every rabbit intact skin and damaged skin were embrocated " sufficient platinum " medicinal liquid, toxigenicity reaction (was seen attached list: the acute toxicity test record).
Sensitivity test: exsomatize and select for use Cavia porcellus, after making guinea pig skin repeat to contact medicinal liquid, observe body immune system and be reflected at the performance on the skin as experimental animal.Select 30 of albino guinea-pigs, body weight 250～300g, male and female half and half are taken off the about 3 * 3cm of the depilation every side of district's scope in preceding 24 hours of administration with the guinea pig back diamond wool
2Select 2, the 4-dinitrochlorobenzene excites the positive sensitizer of concentration with what acetone was processed 1% sensitization solution and 0.1%.Cavia porcellus is divided into 3 groups at random by body weight, sex, 10 every group (male and female half and half).Give for first group and tried the thing medicinal liquid; Second group of blank (solvent: 50% ethanol); The 3rd group of positive thing contrast (giving positive sensitizer).
Carry out sensitization contact, taking liquid 0.2ml is applied to depilation district, Cavia porcellus left side, fixes with nonirritant gauze, adhesive plaster, continues 6 hours, with warm water flush away medicinal liquid.The 7th day and the 14th day, repeat once with same method.Blank group and positive thing matched group method are the same.
Excite contact; After last is given medicinal liquid sensitization 14 days, medicinal liquid 0.2ml is applied to depilation district, guinea pig back right side, and with gauze, immobilization with adhesive tape; After 6 hours with warm water flush away medicinal liquid; At once observe, observed the skin allergy situation once more in 24,48,72 hours then, press table 1 scoring (subordinate list 1--skin allergy standards of grading).Blank group and positive thing contrast method are all with being tried drug group.
After 3 sensitization contact, the visible slight erythema of positive thing matched group disappeared after 3 days; Administration group and blank group be show speckle not all; After exciting contact, the visible edematous erythema of positive thing matched group, still visible after 72 hours; Administration group and blank group be show speckle and edema not.After result of the test is pressed dermoreaction standards of grading scorings, according to the difference of test group with the reaction of matched group guinea pig skin, by table 1 judgement medicinal liquid to skin allergy character (see attached list 3--the evaluation of " sufficient platinum " medicinal liquid skin allergy).The sensitization rate is judged by the classification of subordinate list 2 (the 2--skin irritation of seeing attached list intensity evaluation).The calculating of sensitization rate is divided by the animal subject sum with the animal example number that skin erythema or edema (no matter degree weight) occur.The result shows: " sufficient platinum " medicinal liquid is not seen and is caused tangible skin allergy.
Irritation test: this experiment selected rabbit is observed the IR that behind embrocate on rabbit intact skin and the damaged skin, is produced as experimental animal.Get 6 of healthy rabbits, 24h before the test, every tame rabbit back both sides are first with the about 150cm of curved scissors QUMAO
2, with the depilation of 8% sodium sulfide solution, be divided into 2 groups (3 every group) at random again, promptly intact skin group and damaged skin group behind the depilation 24h, take by weighing rabbit body weight and record.Before the administration rabbit is fixed in the fixed mount, the intact skin group is embrocated medicinal liquid 1ml on left side depilation epidermis, natural airing; 0.9% sodium chloride solution is embrocated in depilation district, right side, does blank.Damaged skin group rabbit depilation epidermis use 75% ethanol disinfection earlier, and the capable network-like cut of reuse aseptic syringe needle is degree to oozing of blood, immediately embrocate 1ml on left side cut oozing of blood loses hair or feathers epidermis, natural airing; Right side cut oozing of blood depilation epidermis is embrocated 0.9% sodium chloride solution, does blank.After non-stimulated husky cloth, immobilization with adhesive tape, send rabbit back to cage position separately, feed and drinking-water affranchise.After 24 hours, observe with the residual reagent thing that receives of warm water flush away.Observe and the recovery situation and the time of phenomenons such as being tried behind the thing 1,24,48,72 hour rabbit skin erythema, edema and these variations removed in record.The result finds, after 1 medication on the one of intact skin group and damaged skin group rabbit, does not all see phenomenons such as skin erythema, edema, spontaneous recovery behind the damaged skin 24h, and every rabbit result of the test is by skin irritation reaction scoring, and erythema and edema score value are 0; Skin irritation intensity score value＜0.5.Show that medicinal liquid is to skin nonirritant (seeing irritation test subordinate list 1, subordinate list 2).
Clinical patients test statistics result shows that the prevention effect of this medicine is fine really:
Receive the reagent thing-a kind of externally-applied powder employed name in clinical that can effectively prevent and treat beriberi, sweaty foot, foot odor to be called " sufficient platinum ", specification: 5 gram/bags, lot number: 20091015, plastic bag packaging.
From year May in November, 2009-2010, we utilize the time of half a year, through to 480 clinical routine patients (male 323 examples, women 157 examples, age 10-76 year) prevention effect analysis, cure 332 examples; 133 examples take a turn for the better; Invalid 15 examples that only account for; Total effective rate reaches 96.87%.(efficacy assessment standard and result see table 1, table 2):
Show through above three cutaneous safeties test and clinical patients statistical result: the present invention is a kind of externally-applied powder that can effectively prevent and treat beriberi, sweaty foot, foot odor really.
The specific embodiment
Embodiment 1: a kind of externally-applied powder and method for preparing of preventing and treating beriberi comprises the raw material of following ratio of quality and the number of copies:
Zinc acetate 15 benzoic acid 13 salicylic acid 10 zinc sulfate 5
Adopt following processing step production:
A. prepare burden: the raw material according to above ratio of quality and the number of copies is formed weighing, puts into the acid-resistant container of getting ready and stirs, and makes its mix homogeneously as far as possible.
B. pulverize: the material of mix homogeneously is poured in the pulverizer pulverized, temperature is 100 ℃ during pulverizing, and the size of pulverizing is controlled at 100 orders.
C. stirred gong: the material that will crush stirs, and carries out the gong processing then and is the semi-finished product material.
D. fill: utilize filling machine that the semi-finished product material is packed in the quantitative bottle, close mouth and seal, add outer package and be product.
Embodiment 2: a kind of externally-applied powder and method for preparing of preventing and treating beriberi comprises the raw material of following ratio of quality and the number of copies:
Zinc acetate 12 benzoic acid 10 salicylic acid 12 zinc sulfate 8
Adopt following processing step production:
A. prepare burden: the raw material according to above ratio of quality and the number of copies is formed weighing, puts into the acid-resistant container of getting ready and stirs, and makes its mix homogeneously as far as possible.
B. pulverize: the material of mix homogeneously is poured in the pulverizer pulverized, temperature does not surpass 80 ℃ during pulverizing, and the size of pulverizing is controlled at 90 orders.
C. stirred gong: the material that will crush stirs, and carries out the gong processing then and is the semi-finished product material.
D. fill: utilize filling machine that the semi-finished product material is packed in the quantitative pouch, close mouth and seal, add outer package and be product.
Claims (2)
1. externally-applied powder of preventing and treating beriberi, its characteristic is made up of the raw material of following ratio of quality and the number of copies:
Zinc acetate 12-15 benzoic acid 10-13 salicylic acid 9-12 zinc sulfate 5-8
Raw material according to above ratio of quality and the number of copies is formed weighing, puts into the acid-resistant container of getting ready and mixes, and through pulverizing, stirring gong, fill, is product.
2. a kind of externally-applied powder of preventing and treating beriberi according to claim 1, its characteristic is made up of the raw material of following ratio of quality and the number of copies:
Zinc acetate 15 benzoic acid 13 salicylic acid 9 zinc sulfate 8.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105361879A CN101972270B (en) | 2010-11-09 | 2010-11-09 | External powder for preventing and curing dermatophytosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105361879A CN101972270B (en) | 2010-11-09 | 2010-11-09 | External powder for preventing and curing dermatophytosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101972270A CN101972270A (en) | 2011-02-16 |
| CN101972270B true CN101972270B (en) | 2012-07-25 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010105361879A Active CN101972270B (en) | 2010-11-09 | 2010-11-09 | External powder for preventing and curing dermatophytosis |
Country Status (1)
| Country | Link |
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| CN (1) | CN101972270B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT511816B1 (en) * | 2012-03-06 | 2013-03-15 | Stefan Winter | Foot powder: Against perspiration and odor |
| CN105832765A (en) * | 2016-05-12 | 2016-08-10 | 段泽恺 | External liquid medicine for preventing and treating beriberi and preparation method thereof |
| KR20230154923A (en) * | 2021-03-31 | 2023-11-09 | 로레알 | New preservative system and cosmetic composition containing the same |
| FR3125415B1 (en) * | 2021-07-22 | 2024-02-02 | Oreal | NEW CONSERVATION SYSTEM |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1047033A (en) * | 1989-05-05 | 1990-11-21 | 程立志 | " one-time efficacious " jiaoqijing (the fragrant manufacture method of revealing of " one-time efficacious " beriberi) |
| CN1065892A (en) * | 1992-05-14 | 1992-11-04 | 彭斌鹏 | Footwear deodorization mildew-resistant cloth and preparation method thereof |
| CN1075873A (en) * | 1993-03-05 | 1993-09-08 | 张效林 | Specific beriberi powder and the method for preparing this athlete foot powder |
| CN1241409A (en) * | 1998-07-10 | 2000-01-19 | 王秉岳 | Lotion for tinea pedis |
| CN101342190A (en) * | 2008-07-26 | 2009-01-14 | 王富才 | Medicament composition for treating beriberi |
| CN101843637A (en) * | 2010-05-17 | 2010-09-29 | 段怀锁 | External spray for preventing and treating beriberi and preparation method |
-
2010
- 2010-11-09 CN CN2010105361879A patent/CN101972270B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1047033A (en) * | 1989-05-05 | 1990-11-21 | 程立志 | " one-time efficacious " jiaoqijing (the fragrant manufacture method of revealing of " one-time efficacious " beriberi) |
| CN1065892A (en) * | 1992-05-14 | 1992-11-04 | 彭斌鹏 | Footwear deodorization mildew-resistant cloth and preparation method thereof |
| CN1075873A (en) * | 1993-03-05 | 1993-09-08 | 张效林 | Specific beriberi powder and the method for preparing this athlete foot powder |
| CN1241409A (en) * | 1998-07-10 | 2000-01-19 | 王秉岳 | Lotion for tinea pedis |
| CN101342190A (en) * | 2008-07-26 | 2009-01-14 | 王富才 | Medicament composition for treating beriberi |
| CN101843637A (en) * | 2010-05-17 | 2010-09-29 | 段怀锁 | External spray for preventing and treating beriberi and preparation method |
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| Publication number | Publication date |
|---|---|
| CN101972270A (en) | 2011-02-16 |
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