CN101970662A - 带有修饰碱基的寡核苷酸作为抗病毒剂的应用 - Google Patents

带有修饰碱基的寡核苷酸作为抗病毒剂的应用 Download PDF

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CN101970662A
CN101970662A CN2008801234555A CN200880123455A CN101970662A CN 101970662 A CN101970662 A CN 101970662A CN 2008801234555 A CN2008801234555 A CN 2008801234555A CN 200880123455 A CN200880123455 A CN 200880123455A CN 101970662 A CN101970662 A CN 101970662A
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modified
compound
oligonucleotide
nucleobases
oligonucleotides
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Chinese (zh)
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马特·萨尔玛
安德烈斯·梅利茨
马蒂·卡拉尔森
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Baltic Technology Development Ltd
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
    • C12N15/1132—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses against retroviridae, e.g. HIV
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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CN2008801234555A 2007-11-05 2008-11-05 带有修饰碱基的寡核苷酸作为抗病毒剂的应用 Pending CN101970662A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US98554807P 2007-11-05 2007-11-05
US60/985,548 2007-11-05
US5768508P 2008-05-30 2008-05-30
US61/057,685 2008-05-30
PCT/FI2008/050633 WO2009060122A2 (en) 2007-11-05 2008-11-05 Use of oligonucleotides with modified bases as antiviral agents

Publications (1)

Publication Number Publication Date
CN101970662A true CN101970662A (zh) 2011-02-09

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CN2008801234555A Pending CN101970662A (zh) 2007-11-05 2008-11-05 带有修饰碱基的寡核苷酸作为抗病毒剂的应用

Country Status (10)

Country Link
US (1) US20110171287A1 (https=)
EP (1) EP2212420A2 (https=)
JP (1) JP5710977B2 (https=)
CN (1) CN101970662A (https=)
AU (1) AU2008324066A1 (https=)
BR (1) BRPI0819191A2 (https=)
CA (1) CA2704549A1 (https=)
MX (1) MX2010004983A (https=)
WO (1) WO2009060122A2 (https=)
ZA (1) ZA201003234B (https=)

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Publication number Priority date Publication date Assignee Title
CN113069551A (zh) * 2014-08-19 2021-07-06 西北大学 蛋白质/寡核苷酸核-壳纳米颗粒治疗剂

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JP2011502501A (ja) 2011-01-27
WO2009060122A2 (en) 2009-05-14
JP5710977B2 (ja) 2015-04-30
WO2009060122A3 (en) 2009-06-25
BRPI0819191A2 (pt) 2017-03-21
US20110171287A1 (en) 2011-07-14
ZA201003234B (en) 2011-06-29
AU2008324066A1 (en) 2009-05-14
CA2704549A1 (en) 2009-05-14
EP2212420A2 (en) 2010-08-04
MX2010004983A (es) 2010-07-29

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