CN101969983B - 治疗和/或预防早产并发症的方法和产品 - Google Patents

治疗和/或预防早产并发症的方法和产品 Download PDF

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CN101969983B
CN101969983B CN200880012284.9A CN200880012284A CN101969983B CN 101969983 B CN101969983 B CN 101969983B CN 200880012284 A CN200880012284 A CN 200880012284A CN 101969983 B CN101969983 B CN 101969983B
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igfbp
igf
insulin
growth factor
rop
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CN101969983A (zh
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安·赫尔斯特罗姆
切特里纳·洛夫克维斯特
罗耶斯·史密斯
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Shire Human Genetics Therapies Inc
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Premacure AB
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1754—Insulin-like growth factor binding proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Reproductive Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN200880012284.9A 2007-04-18 2008-04-18 治疗和/或预防早产并发症的方法和产品 Active CN101969983B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92396307P 2007-04-18 2007-04-18
US60/923,963 2007-04-18
PCT/SE2008/050441 WO2008130315A1 (en) 2007-04-18 2008-04-18 Method and product for treatment and/or prevention of complications of prematurity

Publications (2)

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CN101969983A CN101969983A (zh) 2011-02-09
CN101969983B true CN101969983B (zh) 2014-11-05

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US (3) US8518877B2 (enExample)
EP (1) EP2148695B1 (enExample)
JP (2) JP5449134B2 (enExample)
CN (1) CN101969983B (enExample)
WO (1) WO2008130315A1 (enExample)

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US8518877B2 (en) * 2007-04-18 2013-08-27 Premacure Ab Method and product for treatment and/or prevention of complications of prematurity
CA2888899C (en) 2012-10-24 2023-02-21 Japan Innovative Therapeutics, Inc. Use of tryptase inhibitors in the treatment retinopathy of prematurity
US9510055B2 (en) 2013-01-23 2016-11-29 Sonos, Inc. System and method for a media experience social interface
US20150220498A1 (en) 2014-02-05 2015-08-06 Sonos, Inc. Remote Creation of a Playback Queue for a Future Event
US9679054B2 (en) 2014-03-05 2017-06-13 Sonos, Inc. Webpage media playback
US20150324552A1 (en) 2014-05-12 2015-11-12 Sonos, Inc. Share Restriction for Media Items
US20150356084A1 (en) 2014-06-05 2015-12-10 Sonos, Inc. Social Queue
US9874997B2 (en) 2014-08-08 2018-01-23 Sonos, Inc. Social playback queues
US9959087B2 (en) 2014-09-24 2018-05-01 Sonos, Inc. Media item context from social media
US9690540B2 (en) 2014-09-24 2017-06-27 Sonos, Inc. Social media queue
EP3114852A1 (en) 2014-09-24 2017-01-11 Sonos Inc. Social media queue
US9667679B2 (en) 2014-09-24 2017-05-30 Sonos, Inc. Indicating an association between a social-media account and a media playback system
WO2016049342A1 (en) 2014-09-24 2016-03-31 Sonos, Inc. Social media connection recommendations based on playback information
US10645130B2 (en) 2014-09-24 2020-05-05 Sonos, Inc. Playback updates
US9860286B2 (en) 2014-09-24 2018-01-02 Sonos, Inc. Associating a captured image with a media item
US9723038B2 (en) 2014-09-24 2017-08-01 Sonos, Inc. Social media connection recommendations based on playback information
EP4520828A3 (en) * 2016-11-15 2025-07-09 The Schepens Eye Research Institute, Inc. Compositions and methods for the treatment of aberrant angiogenesis
KR20200097679A (ko) * 2017-09-11 2020-08-19 샤이어 휴먼 지네틱 테라피즈 인크. 만성 폐 질환 치료를 위한 방법 및 조성물
WO2019099560A1 (en) 2017-11-14 2019-05-23 The Schepens Eye Research Institute, Inc. Runx1 inhibition for treatment of proliferative vitreoretinopathy and conditions associated with epithelial to mesenchymal transition
CA3141292A1 (en) * 2019-05-28 2020-12-03 Elgan Pharma Ltd Compositions and methods for treating retinopathy
WO2023242442A1 (en) * 2022-06-17 2023-12-21 Oak Hill Bio Limited Method of maturing/differentiating neurons and/or modulating the vagus nerve
WO2023242440A1 (en) * 2022-06-17 2023-12-21 Oak Hill Bio Limited Treament of lungs in infants
KR20250079196A (ko) * 2022-10-04 2025-06-04 오크 힐 바이오 리미티드 Igf-1 복합체를 이용한 신생아 치료 방법
WO2024160999A1 (en) * 2023-02-03 2024-08-08 Oak Hill Bio Limited Treatment of kidney injury with igf-1 complex
IL322721A (en) * 2023-02-14 2025-10-01 Oak Hill Bio Ltd Treatment of healing dysregulation in digestive tract tissue

Citations (2)

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CN1387440A (zh) * 1999-06-04 2002-12-25 谢尔特里克斯药品公司 治疗糖尿病的方法
WO2007011926A2 (en) * 2005-07-15 2007-01-25 Children's Medical Center Corporation Methods for treating and diagnosing complications of premature birth

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IL71991A (en) 1983-06-06 1994-05-30 Genentech Inc Preparation of human FGI and FGE in their processed form through recombinant AND tranology in prokaryotes
US5187151A (en) * 1991-02-12 1993-02-16 Genentech, Inc. Use of binding protein with igf-i as an anabolic growth promoting agent
AU4238493A (en) * 1992-05-08 1993-12-13 Thomas Jefferson University IGF-1 analogs
US5563046A (en) 1993-08-02 1996-10-08 Celtrix Pharmaceuticals, Inc. Fusion polypeptides and proteins
US5789547A (en) 1995-06-07 1998-08-04 Celtrix Pharmaceuticals, Inc. Method of producing insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-3 (IGFBP-3) with correct folding and disulfide bonding
US6121416A (en) * 1997-04-04 2000-09-19 Genentech, Inc. Insulin-like growth factor agonist molecules
AU2002239560B2 (en) * 2000-11-28 2006-03-02 Premacure Ab Determination of risk and treatment of complications of prematurity
US8518877B2 (en) * 2007-04-18 2013-08-27 Premacure Ab Method and product for treatment and/or prevention of complications of prematurity

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1387440A (zh) * 1999-06-04 2002-12-25 谢尔特里克斯药品公司 治疗糖尿病的方法
WO2007011926A2 (en) * 2005-07-15 2007-01-25 Children's Medical Center Corporation Methods for treating and diagnosing complications of premature birth

Also Published As

Publication number Publication date
EP2148695B1 (en) 2014-10-15
JP5449134B2 (ja) 2014-03-19
EP2148695A4 (en) 2013-01-16
JP2010524928A (ja) 2010-07-22
EP2148695A1 (en) 2010-02-03
US8518877B2 (en) 2013-08-27
US20100204101A1 (en) 2010-08-12
WO2008130315A1 (en) 2008-10-30
US20150216943A1 (en) 2015-08-06
JP2013249317A (ja) 2013-12-12
US20130310316A1 (en) 2013-11-21
US9463222B2 (en) 2016-10-11
CN101969983A (zh) 2011-02-09

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Effective date of registration: 20220117

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Patentee after: SHIRE HUMAN GENETIC THERAPIES, Inc.

Address before: Uppsala, Sweden

Patentee before: Premacure AB