CN101953975A - Oral Chinese medicinal herbal tablets for treating tumors and preparation method - Google Patents
Oral Chinese medicinal herbal tablets for treating tumors and preparation method Download PDFInfo
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- CN101953975A CN101953975A CN2010102996004A CN201010299600A CN101953975A CN 101953975 A CN101953975 A CN 101953975A CN 2010102996004 A CN2010102996004 A CN 2010102996004A CN 201010299600 A CN201010299600 A CN 201010299600A CN 101953975 A CN101953975 A CN 101953975A
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Abstract
The invention relates to a medicament for treating tumor, in particular to oral Chinese medicinal herbal tablets for treating tumors, which are used for treating advanced malignant tumor, inhibiting and shrinking tumor, improving appetite and enhancing physical ability, and a preparation method. The oral Chinese medicinal herbal tablets are prepared from the following raw materials: barbed skullcap herb, bittersweet herb, paris polyphylla, vietnamese sophora root, natural indigo, bezoar, lightyellow sophora root, Chinese pulsatilla root, common dysosmatis rhizome and root, ginseng, cordyceps, wild lucid ganoderma, stiff silkworm, garden balsam, pedate pinallia jackinthepulpit rhizome, radix stephaniae tetrandrae, clematis root, root of hibiscus mutabilis L., and hemsleyae sphaerocarpae radix sources. The preparation method of the oral Chinese medicinal herbal tablets comprises the following steps of: weighing the raw materials of the Chinese medicinal herbal tablets for treating moderate and advanced malignant tumor and drying; crushing the dried raw materials to form particles with diameter of more than 800 meshes; adding amylin into raw material particles, uniformly mixing and preparing into tablets; and drying, checking and packaging the tablets to obtain oral Chinese medicinal herbal tablets for treating tumors. The oral Chinese medicinal herbal tablets for treating tumors have the characteristics of shrinking tumor blood capillary, inhibiting the growth of the tumor cells, along with safe use.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of tumor, particularly a kind ofly be used for the treatment of malignant tumor late period, suppress, the atrophy tumor, but appetite stimulator, strengthen the tumor Chinese herbal medicine tablet for oral administration and the preparation method of physical ability.
Background technology
Malignant tumor is common chronic disease, brings very big misery to the patient.The method and the medicine of treatment malignant tumor are numerous at present, but still there is not the specific drug that the treatment malignant tumor shifted and improved patient's appetite increase physical ability late period up to now, particularly at present still needleless to late tumor (cancer) diffusion and poor appetite and physical weakness, the Chinese medicine preparation that toxic and side effects is less.At present at malignant tumor (cancer) no matter the used Therapeutic Method of doctor trained in Western medicine is operation or Western medicine chemotherapy, radiotherapy all exist many weak points, toxic and side effects is big, operation can only be excised partial focus, damage patient's self healthy energy simultaneously, when killing cancerous cell, the Western medicine chemotherapy also kills the human normal cell, the toxic and side effects of radiation and chemotherapy is the same, patient's resistance is descended, especially the malignant tumor patient DeGrain to having shifted late period, damage patient appetite quicken that sb.'s illness took a turn for the worse.
Summary of the invention
The objective of the invention is at treatment malignant tumor Western medicine and radiotherapy toxic and side effects big, weak point to the malignant tumor patient DeGrain that shifted late period, provide a kind of evident in efficacy, cheap, safe and reliable, better tolerance, patient's compliance height, toxic and side effects little, instant effect, treatment are taken the tumor Chinese herbal medicine tablet for oral administration and the preparation method of no pain.
The technical solution adopted in the present invention is finished in the following way: a kind of tumor is taken the Chinese herbal medicine tablet orally, and the raw material of this tumor Chinese herbal medicine tablet for oral administration comprises Herba Scutellariae Barbatae, Herba Solani Lyrati, Rhizoma Paridis, Radix Sophorae Tonkinensis, Indigo Naturalis, Calculus Bovis, Radix Sophorae Flavescentis, the Radix Pulsatillae, Radix et Rhizoma Dysosmatis, Radix Ginseng, Cordyceps, Wild Ganoderma, Bombyx Batryticatus, Semen Impatientis, Rhizoma Arisaematis, Radix Stephaniae Tetrandrae, Radix Clematidis, Hibisci Mutabilis root, SHELIAN.
In above-mentioned tumor Chinese herbal medicine tablet for oral administration, the weight proportion of tumor Chinese herbal medicine tablet material for oral administration is: 20 parts of Herba Scutellariae Barbataes, 4～6 parts of Herba Solani Lyratis, 10～15 parts of Rhizoma Paridis, 15～25 parts of Radix Sophorae Tonkinensiss, 5～10 parts of Indigo Naturaliss, 8～12 parts of Calculus Boviss, 20～30 parts of Radix Sophorae Flavescentiss, 20～30 parts of the Radix Pulsatillaes, 10～20 parts of Radix et Rhizoma Dysosmatiss, 10～15 parts of Radix Ginsengs, 0.5～2 part of Cordyceps, 5～15 parts of Wild Ganoderma, 10～15 parts of Bombyx Batryticatus, 10～15 parts of Semen Impatientis, 8～12 parts of Rhizoma Arisaematiss, 10～15 parts of Radixs Stephaniae Tetrandrae, 10～15 parts of Radix Clematidis, 8～15 parts of Hibisci Mutabilis roots, 10～15 parts of SHELIAN.
In above-mentioned tumor Chinese herbal medicine tablet for oral administration, tumor Chinese herbal medicine tablet for oral administration is made up of the tumor of microgranule more than 800 orders Chinese herbal medicine tablet material microgranule for oral administration.
The preparation process of tumor of the present invention Chinese herbal medicine tablet for oral administration is:
(1) carry out drying after the raw material that will treat the Chinese herbal medicine tablet of advanced malignant tumor (cancer) weighs up by weight ratio, when dry, temperature is controlled at 40～60 ℃, 4～6 hours drying times;
(2) raw material of above-mentioned dried Chinese herbal medicine tablet is crushed to microgranule more than 800 orders by super micron mill;
(3) make tablet after an amount of dextrin of adding stirs in the feed particles of the Chinese herbal medicine tablet more than above-mentioned 800 orders, wherein, the weight proportion of tumor Chinese herbal medicine tablet material microgranule for oral administration and dextrin is: 100 parts of tumor Chinese herbal medicine tablet material microgranules for oral administration, 1～5 part in dextrin;
(4) tumor Chinese herbal medicine tablet for oral administration is carried out dried;
(5) the Chinese herbal medicine tablet for oral administration of the tumor after the dried is after check, packing, tumor Chinese herbal medicine tablet finished product for oral administration.
Treat the using method of the Chinese medicine preparation of middle and advanced stage tumor (cancer) with the present invention: oral three times of every day of adult, each six, a month course of treatment.
The present invention is based on understanding and the Therapeutic Principle of the traditional Chinese medical science to advanced malignant tumor (cancer), discovers with reference to modern medicines, selects to contain the Chinese herbal medicine of various effective ingredient, forms through the scientific composition practice.Chinese medicine is by the effect of heat-clearing and toxic substances removing, dissipating phlegm and resolving masses, supplementing QI and nourishing YIN, atrophy tumor blood capillary, strengthen the macrophage phagocytic ability, regulate immunity of organisms, improving appetite, thereby strengthen physical ability and play the inhibition growth of tumour cell, improve symptom, alleviate the patient suffering, improve the effect of patients ' life quality.
Find through clinical comparison: after adopting Chinese medicine preparation of the present invention to treat a course of treatment, with compare after course of treatment of matched group (employing chemotherapy and radiation) treatment, adopting the total effective rate of group middle and advanced stage tumor (cancer) treatment of tumor of the present invention Chinese herbal medicine tablet in treatment for oral administration is 93.6%, the total effective rate of matched group centering late tumor (cancer) treatment is 67.8%, and the total effective rate of treatment group is apparently higher than matched group.
The present invention compares with simple use Western medicine chemotherapy, radiotherapy in the treatment, has following characteristics:
1, the present invention selects for use natural Chinese medicinal herb to be raw material, and is safe in utilization, utilizes Chinese herbal medicine Comprehensive Treatment middle and advanced stage tumor (cancer), no obvious toxic-side effects.
2, the present invention has atrophy tumor blood capillary, suppress growth of tumour cell, the effect of human body immunity improving power, the characteristics of having brought into play Chinese medicine heat-clearing and toxic substances removing, dissipating phlegm and resolving masses, supplementing QI and nourishing YIN are suppressing growth of tumour cell, improve appetite, recover physical ability, alleviate the last effect of patient suffering significantly.
The specific embodiment
Below by embodiment the present invention is made further and to specify, but the invention is not restricted to these embodiment.
Embodiment 1
The tumor of a kind of treatment middle and advanced stage tumor (cancer) is taken the Chinese herbal medicine tablet orally; it is that Chinese herbal medicine by the following weight proportioning is the Chinese herbal medicine tablet for oral administration that raw material is made, wherein 20 parts of Herba Scutellariae Barbataes, 5 parts of Herba Solani Lyratis, 15 parts of Rhizoma Paridis, 20 parts of Radix Sophorae Tonkinensiss, 5 parts of Indigo Naturaliss, 10 parts of Calculus Boviss, 30 parts of Radix Sophorae Flavescentiss, 25 parts of the Radix Pulsatillaes, 15 parts of Radix et Rhizoma Dysosmatiss, 10 parts of Radix Ginsengs, 1 part of Cordyceps, 10 parts of Wild Ganoderma, 15 parts of Bombyx Batryticatus, 15 parts of Semen Impatientis, 10 parts of Rhizoma Arisaematiss, 15 parts of Radixs Stephaniae Tetrandrae, 15 parts of Radix Clematidis, 10 parts of Hibisci Mutabilis roots, 10 parts of SHELIAN.
The preparation process of tumor Chinese herbal medicine tablet for oral administration is: the raw material of the Chinese herbal medicine tablet of above-mentioned treatment advanced malignant tumor (cancer) through 40～60 ℃, after dry 4～6 hours, is crushed to microgranule more than 800 orders by super micron mill; In the feed particles of Chinese herbal medicine tablet, add and make tablet after dextrin stirs by 1～5% of feed particles weight, after tablet drying, check, the packing, tumor Chinese herbal medicine tablet finished product for oral administration.
Embodiment 2
The tumor of a kind of treatment middle and advanced stage tumor (cancer) is taken the Chinese herbal medicine tablet orally; it is that Chinese herbal medicine by the following weight proportioning is the Chinese herbal medicine tablet for oral administration that raw material is made, wherein 20 parts of Herba Scutellariae Barbataes, 4 parts of Herba Solani Lyratis, 15 parts of Rhizoma Paridis, 15 parts of Radix Sophorae Tonkinensiss, 10 parts of Indigo Naturaliss, 8 parts of Calculus Boviss, 30 parts of Radix Sophorae Flavescentiss, 20 parts of the Radix Pulsatillaes, 20 parts of Radix et Rhizoma Dysosmatiss, 10 parts of Radix Ginsengs, 0.5 part of Cordyceps, 15 parts of Wild Ganoderma, 10 parts of Bombyx Batryticatus, 15 parts of Semen Impatientis, 8 parts of Rhizoma Arisaematiss, 15 parts of Radixs Stephaniae Tetrandrae, 10 parts of Radix Clematidis, 8 parts of Hibisci Mutabilis roots, 15 parts of SHELIAN.
The preparation process of tumor Chinese herbal medicine tablet for oral administration is identical with embodiment 1.
Embodiment 3
The tumor of a kind of treatment middle and advanced stage tumor (cancer) is taken the Chinese herbal medicine tablet orally; it is that Chinese herbal medicine by the following weight proportioning is the Chinese herbal medicine tablet for oral administration that raw material is made, wherein 20 parts of Herba Scutellariae Barbataes, 6 parts of Herba Solani Lyratis, 10 parts of Rhizoma Paridis, 25 parts of Radix Sophorae Tonkinensiss, 5 parts of Indigo Naturaliss, 12 parts of Calculus Boviss, 20 parts of Radix Sophorae Flavescentiss, 30 parts of the Radix Pulsatillaes, 10 parts of Radix et Rhizoma Dysosmatiss, 15 parts of Radix Ginsengs, 2 parts of Cordycepses, 5 parts of Wild Ganoderma, 15 parts of Bombyx Batryticatus, 10 parts of Semen Impatientis, 12 parts of Rhizoma Arisaematiss, 10 parts of Radixs Stephaniae Tetrandrae, 15 parts of Radix Clematidis, 15 parts of Hibisci Mutabilis roots, 10 parts of SHELIAN.
The preparation process of tumor Chinese herbal medicine tablet for oral administration is identical with embodiment 1.
Reference examples
Therapeutic effect for check centering late tumor of the present invention (cancer) carries out following clinical trial to the present invention, and its clinical experiment report is as follows:
1, case is selected
Selection meets case 376 examples of middle and advanced stage tumor (cancer) diagnostic criteria, patient is divided into two groups at random, 188 examples are organized in treatment, wherein male 86 examples (pulmonary carcinoma 20 examples, gastric cancer 23 examples, hepatocarcinoma 12 examples, rectal cancer 9 examples, bladder cancer 5 examples, esophageal carcinoma 6 examples, cerebroma 6 examples, malignant lymphoma 5 examples), women 102 examples (pulmonary carcinoma 14 examples, gastric cancer 13 examples, hepatocarcinoma 10 examples, rectal cancer 6 examples, esophageal carcinoma 8 examples, cerebroma 5 examples, mammary cancer 12 routine cervical cancer 11 routine ovarian cancer 9 examples, malignant lymphoma 7 examples, leukemia 7 examples); 23～82 years old age, 52.6 years old mean age; The course of disease 3～16 months, average 8.7 months.Matched group 188 examples, wherein male 92 examples (pulmonary carcinoma 21 examples, gastric cancer 27, hepatocarcinoma 13 examples, rectal cancer 8 examples, bladder cancer 7 examples, esophageal carcinoma 6 examples, cerebroma 5 examples, malignant lymphoma 5 examples), women 96 examples (pulmonary carcinoma 12 examples, gastric cancer 11 examples, hepatocarcinoma 8 examples, rectal cancer 6 examples, esophageal carcinoma 8 examples, cerebroma 5 examples, mammary cancer 12 examples, cervical cancer 11 examples, ovarian cancer 9 routine malignant lymphoma 7 examples, leukemia 7 examples); 28～81 years old age, 51.8 years old mean age; The course of disease 4～15 months, average 7.9 months.Two groups of qualifications and record of service basically identicals, there was no significant difference has comparability.
2, treatment group patient takes Chinese medicine preparation of the present invention, oral 3 times of every day of adult, each 6, two months courses of treatment.Matched group adopts chemotherapy and radiation
3, criterion
Produce effects: tumor tumor body dwindles more than 5%, and subjective symptoms is obviously improved, and cardinal symptom disappears;
Effectively: tumor tumor body dwindles 2～5%, and clinical symptoms is obviously improved;
Improve: tumor tumor body is kept original size, and clinical symptoms is improved;
Invalid: tumor tumor body continuation growth and clinical symptoms do not have improvement or increase the weight of.
4, result
Take in the treatment group of the present invention produce effects: 92 examples, effective 59 examples are improved 35 examples, invalid 10 examples, total effective rate 93.6%.
Produce effects 63 examples in the matched group, effective 46 examples are improved 17 examples, invalid 60 examples, total effective rate 67.8%.
The total effective rate of treatment group is apparently higher than matched group.
Claims (6)
1. a tumor is taken the Chinese herbal medicine tablet orally, it is characterized in that: the raw material of this tumor Chinese herbal medicine tablet for oral administration comprises Herba Scutellariae Barbatae, Herba Solani Lyrati, Rhizoma Paridis, Radix Sophorae Tonkinensis, Indigo Naturalis, Calculus Bovis, Radix Sophorae Flavescentis, the Radix Pulsatillae, Radix et Rhizoma Dysosmatis, Radix Ginseng, Cordyceps, Wild Ganoderma, Bombyx Batryticatus, Semen Impatientis, Rhizoma Arisaematis, Radix Stephaniae Tetrandrae, Radix Clematidis, Hibisci Mutabilis root, SHELIAN.
2. tumor according to claim 1 is taken the Chinese herbal medicine tablet orally, it is characterized in that: the weight proportion of tumor Chinese herbal medicine tablet material for oral administration is: 20 parts of Herba Scutellariae Barbataes, Herba Solani Lyrati 4-6 part, Rhizoma Paridis 10-15 part, Radix Sophorae Tonkinensis 15-25 part, Indigo Naturalis 5-10 part, Calculus Bovis 8-12 part, Radix Sophorae Flavescentis 20-30 part, Radix Pulsatillae 20-30 part, Radix et Rhizoma Dysosmatis 10-20 part, Radix Ginseng 10-15 part, Cordyceps 0.5-2 part, Wild Ganoderma 5-15 part, Bombyx Batryticatus 10-15 part, Semen Impatientis 10-15 part, Rhizoma Arisaematis 8-12 part, Radix Stephaniae Tetrandrae 10-15 part, Radix Clematidis 10-15 part, Hibisci Mutabilis root 8-15 part, SHELIAN 10-15 part.
3. tumor according to claim 1 and 2 is taken the Chinese herbal medicine tablet orally, it is characterized in that: tumor Chinese herbal medicine tablet for oral administration is made up of the tumor of microgranule more than 800 orders Chinese herbal medicine tablet material microgranule for oral administration.
4. the preparation method of a kind of tumor according to claim 1 and 2 Chinese herbal medicine tablet for oral administration is characterized in that: the preparation process of tumor Chinese herbal medicine tablet for oral administration is:
(1) carries out drying after the raw material that will treat the Chinese herbal medicine tablet of advanced malignant tumor (cancer) weighs up by weight ratio;
(2) raw material of above-mentioned dried Chinese herbal medicine tablet is crushed to microgranule more than 800 orders by super micron mill;
(3) make tablet after an amount of dextrin of adding stirs in the feed particles of the Chinese herbal medicine tablet more than above-mentioned 800 orders;
(4) tumor Chinese herbal medicine tablet for oral administration is carried out dried;
(5) the Chinese herbal medicine tablet for oral administration of the tumor after the dried is after check, packing, tumor Chinese herbal medicine tablet finished product for oral administration.
5. the preparation method of a kind of tumor according to claim 4 Chinese herbal medicine tablet for oral administration is characterized in that: when tumor Chinese herbal medicine tablet material for oral administration was carried out drying, temperature was controlled at 40～60 ℃, 4～6 hours drying times.
6. the preparation method of a kind of tumor according to claim 4 Chinese herbal medicine tablet for oral administration is characterized in that: the weight proportion of tumor Chinese herbal medicine tablet material microgranule for oral administration and dextrin is: 100 parts of tumor Chinese herbal medicine tablet material microgranules for oral administration, 1～5 part in dextrin.
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| CN2010102996004A CN101953975B (en) | 2010-09-30 | 2010-09-30 | Oral Chinese medicinal herbal tablets for treating tumors and preparation method |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102397398A (en) * | 2011-11-23 | 2012-04-04 | 暨南大学 | Traditional Chinese medicine composition for reversing tumor multidrug resistance and preparation method and application thereof |
| CN107468871A (en) * | 2017-09-27 | 2017-12-15 | 张存法 | A kind of Chinese medicine composition for treating tumour and preparation method thereof |
| US10421903B2 (en) | 2014-06-05 | 2019-09-24 | Joinstar Biomedical Technology Co., Ltd. | Carrier particle and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1247757A (en) * | 1999-05-19 | 2000-03-22 | 赵国民 | Cancer treating medicine capsule |
| CN1698685A (en) * | 2004-05-18 | 2005-11-23 | 张明生 | Medicament composition for treating tumour |
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- 2010-09-30 CN CN2010102996004A patent/CN101953975B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1247757A (en) * | 1999-05-19 | 2000-03-22 | 赵国民 | Cancer treating medicine capsule |
| CN1698685A (en) * | 2004-05-18 | 2005-11-23 | 张明生 | Medicament composition for treating tumour |
Non-Patent Citations (1)
| Title |
|---|
| 《中国医药指南》 20070905 刘因华 抗肿瘤药物的研究现状与发展前景 105-108 1-6 , 2 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102397398A (en) * | 2011-11-23 | 2012-04-04 | 暨南大学 | Traditional Chinese medicine composition for reversing tumor multidrug resistance and preparation method and application thereof |
| US10421903B2 (en) | 2014-06-05 | 2019-09-24 | Joinstar Biomedical Technology Co., Ltd. | Carrier particle and preparation method thereof |
| CN107468871A (en) * | 2017-09-27 | 2017-12-15 | 张存法 | A kind of Chinese medicine composition for treating tumour and preparation method thereof |
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| CN101953975B (en) | 2012-02-01 |
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