CN101939814B - 通过同时的尺寸/荧光测量进行的病原体检测 - Google Patents

通过同时的尺寸/荧光测量进行的病原体检测 Download PDF

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Publication number
CN101939814B
CN101939814B CN200880126481.3A CN200880126481A CN101939814B CN 101939814 B CN101939814 B CN 101939814B CN 200880126481 A CN200880126481 A CN 200880126481A CN 101939814 B CN101939814 B CN 101939814B
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particle
light
fluorescence
particles
detector
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CN101939814A (zh
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埃里克·H·比妮
格雷戈里·斯科特·莫里斯
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Baer Times Police Co
Azbil Corp
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Biovigilant Systems Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/34—Measuring or testing with condition measuring or sensing means, e.g. colony counters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/53—Scattering, i.e. diffuse reflection within a body or fluid within a flowing fluid, e.g. smoke
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J40/00—Photoelectric discharge tubes not involving the ionisation of a gas
    • H01J40/02—Details
    • H01J40/14—Circuit arrangements not adapted to a particular application of the tube and not otherwise provided for
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/22—Devices for withdrawing samples in the gaseous state
    • G01N1/2247—Sampling from a flowing stream of gas
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/22—Devices for withdrawing samples in the gaseous state
    • G01N1/2273—Atmospheric sampling
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/019—Biological contaminants; Fouling
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0205—Investigating particle size or size distribution by optical means
    • G01N2015/025—Methods for single or grouped particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1486—Counting the particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1493—Particle size
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/061—Sources
    • G01N2201/06113—Coherent sources; lasers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/061—Sources
    • G01N2201/06193—Secondary in situ sources, e.g. fluorescent particles

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  • Health & Medical Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Sustainable Development (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CN200880126481.3A 2007-12-13 2008-12-15 通过同时的尺寸/荧光测量进行的病原体检测 Expired - Fee Related CN101939814B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1360707P 2007-12-13 2007-12-13
US61/013,607 2007-12-13
PCT/US2008/086886 WO2009076678A1 (en) 2007-12-13 2008-12-15 Pathogen detection by simultaneous size/fluorescence measurement

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CN101939814A CN101939814A (zh) 2011-01-05
CN101939814B true CN101939814B (zh) 2014-02-26

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US (2) US20110036995A1 (enExample)
EP (1) EP2235736B1 (enExample)
JP (1) JP2011506977A (enExample)
KR (1) KR101581056B1 (enExample)
CN (1) CN101939814B (enExample)
WO (1) WO2009076678A1 (enExample)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8378661B1 (en) * 2008-05-29 2013-02-19 Alpha-Omega Power Technologies, Ltd.Co. Solar simulator
DE102009020252B4 (de) * 2009-05-07 2012-01-12 Krohne Optosens Gmbh Vorrichtung zur Messung der Fluoreszenz eines Mediums
FI20105645A0 (fi) * 2010-06-07 2010-06-07 Environics Oy Laite ja menetelmä biologisen materiaalin havaitsemiseksi
KR20120071453A (ko) * 2010-12-23 2012-07-03 삼성전자주식회사 미생물 검출장치
KR20120074558A (ko) * 2010-12-28 2012-07-06 삼성전자주식회사 미세입자 검출장치
WO2012098287A1 (en) * 2011-01-19 2012-07-26 Teknologian Tutkimuskeskus Vtt Method and system for determining particle size information
CN103492585A (zh) * 2011-04-06 2014-01-01 即时生物检测有限公司 微生物检测装置和方法
JP2014006108A (ja) * 2012-06-22 2014-01-16 Azbil Corp 光学式粒子検出装置及び粒子の検出方法
KR101411428B1 (ko) 2012-07-12 2014-06-24 한국과학기술원 집광식 휴대용 형광 검출 시스템
JP2014035246A (ja) * 2012-08-08 2014-02-24 Azbil Corp 粒子検出装置の光源情報記録装置及び粒子検出装置の光源情報記録方法
JP6076680B2 (ja) * 2012-10-15 2017-02-08 アズビル株式会社 不溶性不純物判別方法及びその装置
JP5993704B2 (ja) * 2012-10-18 2016-09-14 アズビル株式会社 気中液中粒子判別方法及びその装置
JP5993752B2 (ja) * 2013-02-01 2016-09-14 アズビル株式会社 粒子検出システム及び粒子検出方法
JP6031372B2 (ja) * 2013-02-12 2016-11-24 アズビル株式会社 粒子検出システム及び粒子検出方法
US9400250B2 (en) * 2013-09-30 2016-07-26 Han Sheng Biotech Co., Ltd. Method for analyzing mushrooms
JP6138037B2 (ja) * 2013-12-10 2017-05-31 アズビル株式会社 粒子検出装置及び粒子の検出方法
CN103940709A (zh) * 2014-05-06 2014-07-23 南京中科神光科技有限公司 一种实时微生物粒子计数器
JP6425918B2 (ja) * 2014-05-27 2018-11-21 アズビル株式会社 精製水製造装置の監視システム及び精製水製造装置の監視方法
DE102014215735A1 (de) * 2014-08-08 2016-02-11 Robert Bosch Gmbh Verfahren zum Betreiben einer raumlufttechnischen Anlage, Sensor und raum-lufttechnische Anlage
JP6438319B2 (ja) * 2015-02-18 2018-12-12 アズビル株式会社 粒子検出装置
KR102258807B1 (ko) * 2015-02-24 2021-06-09 (주)미디어에버 미세 먼지 및 미생물 검출 장치
KR102258809B1 (ko) * 2015-02-24 2021-06-09 (주)미디어에버 미세 먼지 및 미생물 검출 장치
US9791370B2 (en) 2015-04-14 2017-10-17 Honeywell International Inc. Die-integrated aspheric mirror
US10613029B2 (en) * 2015-04-14 2020-04-07 Honeywell International Inc. Apparatus and method for forming an alignment cell
CN104931471A (zh) * 2015-06-08 2015-09-23 北京大学 大气活性自由基的激光诱导荧光检测系统
WO2017104533A1 (ja) * 2015-12-14 2017-06-22 三菱電機株式会社 微小物検出装置
US20190154560A1 (en) * 2016-05-16 2019-05-23 Abbvie Inc. Systems and Methods for Identifying Protein Aggregates in Biotherapeutics
JP6714427B2 (ja) * 2016-05-17 2020-06-24 アズビル株式会社 粒子検出装置及び粒子検出装置の検査方法
KR101967671B1 (ko) * 2016-11-08 2019-04-11 한국전자통신연구원 필터 상태 모니터링 방법 및 그 방법을 수행하는 필터 상태 모니터링 장치
KR102450625B1 (ko) * 2017-08-31 2022-10-07 서울바이오시스 주식회사 검출기
US10267723B1 (en) 2018-01-23 2019-04-23 Cbrn International, Ltd. Bioaerosol particle detector
WO2019232450A1 (en) * 2018-06-01 2019-12-05 Orb Xyz, Inc. Detection of biological substances
US12019023B2 (en) 2018-06-01 2024-06-25 Orb Xyz, Inc. Detecting an analyte in a medium
CN108709848A (zh) * 2018-07-25 2018-10-26 佛山融芯智感科技有限公司 一种空气颗粒计数方法及装置
CN110967284A (zh) * 2019-05-17 2020-04-07 南京工业大学 一种双通道生物气溶胶实时监测仪
CN114402191A (zh) * 2019-10-09 2022-04-26 松下知识产权经营株式会社 摄影装置
US20240319063A1 (en) 2020-04-26 2024-09-26 Viktor TOMASOV Airborne bacteria detection system
WO2022005812A1 (en) * 2020-06-29 2022-01-06 Spekciton Biosciences Llc Duvf-msi biophotonic analyzer device and methods for detecting pathogens on plants and measuring stress response
FR3112386B1 (fr) * 2020-07-10 2024-01-19 Commissariat Energie Atomique Système de caractérisation de particules se présentant sous la forme d’un aérosol dans un gaz ambiant et procédé associé.
CN113945490B (zh) * 2020-07-17 2025-05-02 航天神舟生物科技集团有限公司 一种激光粒子检测装置
CN113720750B (zh) * 2021-08-31 2023-07-28 北京航空航天大学 一种光学颗粒计数器
CN114459965A (zh) * 2021-12-30 2022-05-10 中船重工安谱（湖北）仪器有限公司 一种气溶胶监测系统及方法
WO2023154252A1 (en) * 2022-02-10 2023-08-17 ColdQuanta, Inc. Miniature atomic spectroscopy reference cell system
WO2025116166A1 (ko) * 2023-12-01 2025-06-05 엘지전자 주식회사 산란광 및 형광 검출 장치
KR102831100B1 (ko) * 2023-12-07 2025-07-07 한국전자기술연구원 공기중 부유 미생물의 실시간 모니터링 장치
CN119246387B (zh) * 2024-12-09 2025-03-25 苏州胤煌精密仪器科技有限公司 一种颗粒检测装置

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3850525A (en) * 1973-07-09 1974-11-26 Beckman Instruments Inc Simultaneous multiple measurements in laser photometers
JP2560362B2 (ja) * 1987-12-18 1996-12-04 富士通株式会社 多重反射鏡
EP0515211A3 (en) * 1991-05-23 1993-04-07 Becton Dickinson And Company Apparatus and method for phase resolved fluorescence lifetimes of independent and varying amplitude pulses
US5540494A (en) * 1994-06-03 1996-07-30 Purvis, Jr.; Norman B. Method and apparatus for determining absolute particle size, surface area and volume normalized fluorescence using forward angle light scatter intensity in flow cytometry
US5895922A (en) 1996-03-19 1999-04-20 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of National Defence Fluorescent biological particle detection system
US5701012A (en) 1996-03-19 1997-12-23 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of National Defence Fluorescent biological particle detection system
WO1998041876A1 (en) 1997-03-17 1998-09-24 Tsi Incorporated System for detecting fluorescing components in aerosols
US5870190A (en) * 1997-11-25 1999-02-09 Venturedyne, Ltd. Particle sensor and related method offering improved particle discrimination
AU2001276867A1 (en) * 2000-07-11 2002-01-21 Sri International Encoding methods using up-converting phosphors for high-throughput screening of catalysts
US6787104B1 (en) * 2000-09-14 2004-09-07 The Regents Of The University Of California Detection and treatment of chemical weapons and/or biological pathogens
US6594009B2 (en) * 2001-02-27 2003-07-15 Honeywell International Inc. Flow cytometer and ultraviolet light disinfecting systems
AU2002367966B2 (en) 2001-11-07 2008-06-19 S3I L.L.C. System and method for detecting and classifying biological particles
US6831279B2 (en) * 2001-11-27 2004-12-14 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of National Defence Laser diode-excited biological particle detection system
WO2004001382A2 (en) * 2002-06-24 2003-12-31 Tsi Incorporated Analysis systems detecting particle size and fluorescence
US7053783B2 (en) * 2002-12-18 2006-05-30 Biovigilant Systems, Inc. Pathogen detector system and method
US6936828B2 (en) * 2003-02-14 2005-08-30 Honeywell International Inc. Particle detection system and method
US20060237665A1 (en) * 2003-03-10 2006-10-26 Barney William S Bioaerosol discrimination
EP1620710A2 (en) 2003-04-29 2006-02-01 S3I, Llc A multi-spectral optical method and system for detecting and classifying biological and non-biological particles
WO2006073492A2 (en) * 2004-07-30 2006-07-13 Biovigilant Systems, Inc. Pathogen and particle detector system and method
WO2007063862A1 (ja) * 2005-11-29 2007-06-07 Nidec Sankyo Corporation 粒子計数器及びそれを備えた粒子計数装置、粒子計数システム及びその使用方法

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EP2235736B1 (en) 2015-04-01
US20150168288A1 (en) 2015-06-18
EP2235736A4 (en) 2011-09-07
WO2009076678A1 (en) 2009-06-18
JP2011506977A (ja) 2011-03-03
CN101939814A (zh) 2011-01-05
EP2235736A1 (en) 2010-10-06
US20110036995A1 (en) 2011-02-17
KR101581056B1 (ko) 2015-12-29
KR20110005677A (ko) 2011-01-18

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