CN101939651A - 用于检测严重有害的心血管和脑血管事件的方法 - Google Patents

用于检测严重有害的心血管和脑血管事件的方法 Download PDF

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Publication number
CN101939651A
CN101939651A CN2008801210762A CN200880121076A CN101939651A CN 101939651 A CN101939651 A CN 101939651A CN 2008801210762 A CN2008801210762 A CN 2008801210762A CN 200880121076 A CN200880121076 A CN 200880121076A CN 101939651 A CN101939651 A CN 101939651A
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CN
China
Prior art keywords
serious adverse
adverse cardiovascular
analytes
analyte
human
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Pending
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CN2008801210762A
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English (en)
Chinese (zh)
Inventor
P·蒙滕丹
R·巴拉苏布拉马尼安
R·迈尔斯
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BG Medicine Inc
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BG Medicine Inc
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Publication of CN101939651A publication Critical patent/CN101939651A/zh
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0009—Calibration of the apparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G01N2333/7454—Tissue factor (tissue thromboplastin, Factor III)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2871—Cerebrovascular disorders, e.g. stroke, cerebral infarct, cerebral haemorrhage, transient ischemic event
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/325—Heart failure or cardiac arrest, e.g. cardiomyopathy, congestive heart failure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Electrotherapy Devices (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
CN2008801210762A 2007-10-10 2008-10-10 用于检测严重有害的心血管和脑血管事件的方法 Pending CN101939651A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US99856307P 2007-10-10 2007-10-10
US60/998563 2007-10-10
US99875607P 2007-10-11 2007-10-11
US60/998756 2007-10-11
PCT/US2008/079553 WO2009049189A2 (en) 2007-10-10 2008-10-10 Methods for detecting major adverse cardiovascular and cerebrovascular events

Publications (1)

Publication Number Publication Date
CN101939651A true CN101939651A (zh) 2011-01-05

Family

ID=40289424

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2008801210762A Pending CN101939651A (zh) 2007-10-10 2008-10-10 用于检测严重有害的心血管和脑血管事件的方法

Country Status (10)

Country Link
US (1) US20110045514A1 (https=)
EP (1) EP2210108B1 (https=)
JP (1) JP2011501133A (https=)
CN (1) CN101939651A (https=)
AT (1) ATE536553T1 (https=)
AU (1) AU2008310669A1 (https=)
CA (1) CA2702268A1 (https=)
ES (1) ES2374762T3 (https=)
IL (1) IL204922A0 (https=)
WO (1) WO2009049189A2 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105866261A (zh) * 2016-03-24 2016-08-17 中国药科大学 诊断区分稳定型心绞痛和急性冠脉综合征的代谢标志物群
WO2017128162A1 (zh) * 2016-01-25 2017-08-03 齐炼文 诊断区分冠状动脉粥样硬化和稳定型心绞痛的代谢标志物
WO2017128161A1 (zh) * 2016-01-25 2017-08-03 齐炼文 诊断区分稳定型心绞痛和急性冠脉综合征的代谢标志物
CN108027354A (zh) * 2015-08-20 2018-05-11 深圳华大生命科学研究院 冠心病的生物标志物

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US8620738B2 (en) * 2006-08-31 2013-12-31 Visa U.S.A. Inc Loyalty program incentive determination
GB0717637D0 (en) 2007-09-10 2007-10-17 Univ Leiden Future cardiac event biomarkers
EP2199956A1 (en) * 2008-12-18 2010-06-23 Siemens Aktiengesellschaft Method and system for managing results of an analysis process on objects handled along a technical process line
KR20120101064A (ko) 2009-11-13 2012-09-12 비쥐 메디신, 인코포레이티드 심근 경색의 위험 인자 및 예측
US9285378B2 (en) * 2010-01-29 2016-03-15 Metanomics Gmbh Means and methods for diagnosing heart failure in a subject
ES2728120T3 (es) * 2010-01-29 2019-10-22 Metanomics Gmbh Medios y procedimientos para diagnosticar insuficiencia cardíaca en un sujeto
WO2012035412A2 (en) * 2010-09-15 2012-03-22 Dh Technologies Development Pte. Ltd. Data independent acquisition of production spectra and reference spectra library matching
EP2592422A1 (en) * 2011-11-08 2013-05-15 Zora Biosciences OY Lipidomic biomarkers for the prediction of cardiovascular outcomes in coronary artery disease patients undergoing statin treatment
ES2897573T3 (es) * 2012-03-26 2022-03-01 Xcellcure Llc Dispositivo y procedimiento para la detección de analitos
CA2907120C (en) 2013-03-15 2023-10-17 Sera Prognostics, Inc. Biomarkers and methods for predicting preterm birth
KR101660328B1 (ko) 2014-01-14 2016-09-27 한국과학기술연구원 심혈관 질환 진단용 바이오 마커
CN106457090B (zh) 2014-04-10 2020-09-29 Mep马解决方案有限责任公司 粪便中寄生虫卵的定量方法
WO2016011434A1 (en) * 2014-07-18 2016-01-21 Landis Darryl Use of an evidence-based, translational algorithm to, inter alia, assess biomarkers
US20180238914A1 (en) * 2015-08-19 2018-08-23 Metanomics Gmbh Means and methods for diagnosing cardiac disease in a subject
CN105223264B (zh) * 2015-09-21 2017-12-29 广东联捷生物科技有限公司 一种质谱定量分析的模拟内标方法、装置及应用
JP7109374B2 (ja) 2016-04-14 2022-07-29 エフ．ホフマン－ラ ロシュ アーゲー 体液の試料中の標的分析物の濃度を決定するための方法
EP4545968A3 (en) * 2017-12-13 2026-03-18 GLX Analytix ApS Biomarkers for multiple sclerosis
JP7280582B2 (ja) * 2018-09-12 2023-05-24 株式会社島津製作所 心房細動指標値の測定方法
CN109799296A (zh) * 2019-01-28 2019-05-24 江南大学 一种用于细胞非靶向代谢组学分析的样品前处理方法
EP4135565A4 (en) * 2020-04-17 2024-05-01 The Regents Of The University Of California SYSTEMS AND METHODS FOR CLASSIFYING CRITICAL HEART DEFECTS

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US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US4704692A (en) 1986-09-02 1987-11-03 Ladner Robert C Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides
US5091513A (en) 1987-05-21 1992-02-25 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
US5132405A (en) 1987-05-21 1992-07-21 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
US20070003981A1 (en) * 2005-06-29 2007-01-04 Rules-Based Medicine, Inc. Methods and kits for the diagnosis of acute coronary syndrome
WO2007124439A2 (en) * 2006-04-21 2007-11-01 Rules-Based Medicine, Inc. Diagnosis of stroke using metalloproteinase or transaminase

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108027354A (zh) * 2015-08-20 2018-05-11 深圳华大生命科学研究院 冠心病的生物标志物
WO2017128162A1 (zh) * 2016-01-25 2017-08-03 齐炼文 诊断区分冠状动脉粥样硬化和稳定型心绞痛的代谢标志物
WO2017128161A1 (zh) * 2016-01-25 2017-08-03 齐炼文 诊断区分稳定型心绞痛和急性冠脉综合征的代谢标志物
CN105866261A (zh) * 2016-03-24 2016-08-17 中国药科大学 诊断区分稳定型心绞痛和急性冠脉综合征的代谢标志物群

Also Published As

Publication number Publication date
ATE536553T1 (de) 2011-12-15
WO2009049189A3 (en) 2009-06-18
US20110045514A1 (en) 2011-02-24
WO2009049189A2 (en) 2009-04-16
EP2210108B1 (en) 2011-12-07
CA2702268A1 (en) 2009-04-16
EP2210108A2 (en) 2010-07-28
IL204922A0 (en) 2010-11-30
AU2008310669A1 (en) 2009-04-16
ES2374762T3 (es) 2012-02-21
JP2011501133A (ja) 2011-01-06

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