CN101939014B - 亚硝酸盐在慢性缺血中的应用 - Google Patents

亚硝酸盐在慢性缺血中的应用 Download PDF

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Publication number
CN101939014B
CN101939014B CN200880116483.4A CN200880116483A CN101939014B CN 101939014 B CN101939014 B CN 101939014B CN 200880116483 A CN200880116483 A CN 200880116483A CN 101939014 B CN101939014 B CN 101939014B
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CN
China
Prior art keywords
nitrite
tissue
ischemic
chronic
sodium nitrite
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CN200880116483.4A
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English (en)
Chinese (zh)
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CN101939014A (zh
Inventor
克里斯托弗·凯维尔
大卫·勒费
拉凯什·帕特尔
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UAB Research Foundation
Louisiana State University
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UAB Research Foundation
Louisiana State University
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN200880116483.4A 2007-11-15 2008-11-17 亚硝酸盐在慢性缺血中的应用 Expired - Fee Related CN101939014B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US315007P 2007-11-15 2007-11-15
US61/003,150 2007-11-15
PCT/US2008/083830 WO2009065142A2 (en) 2007-11-15 2008-11-17 Use of nitrite salts in chronic ischemia

Publications (2)

Publication Number Publication Date
CN101939014A CN101939014A (zh) 2011-01-05
CN101939014B true CN101939014B (zh) 2016-04-27

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Family Applications (1)

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CN200880116483.4A Expired - Fee Related CN101939014B (zh) 2007-11-15 2008-11-17 亚硝酸盐在慢性缺血中的应用

Country Status (7)

Country Link
US (2) US9649334B2 (cg-RX-API-DMAC10.html)
EP (1) EP2219657A4 (cg-RX-API-DMAC10.html)
JP (2) JP5795165B2 (cg-RX-API-DMAC10.html)
CN (1) CN101939014B (cg-RX-API-DMAC10.html)
AU (1) AU2008322437B2 (cg-RX-API-DMAC10.html)
IL (1) IL205720A (cg-RX-API-DMAC10.html)
WO (1) WO2009065142A2 (cg-RX-API-DMAC10.html)

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* Cited by examiner, † Cited by third party
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WO2009065142A2 (en) 2007-11-15 2009-05-22 Biomedical Research Foundation Of Northwest Louisiana Use of nitrite salts in chronic ischemia
US8568793B2 (en) 2009-02-11 2013-10-29 Hope Medical Enterprises, Inc. Sodium nitrite-containing pharmaceutical compositions
WO2010147742A2 (en) * 2009-06-18 2010-12-23 Theravasc Inc. Use of nitrite salts in treating tissue damage
CN107260756A (zh) 2009-10-14 2017-10-20 瑟阿瓦斯克有限公司 亚硝酸盐/酯的药物制剂以及其应用
US20130209584A1 (en) * 2009-10-14 2013-08-15 Theravasc Inc. Pharmaceutical formulations of nitrite and uses thereof
CN105358160A (zh) 2013-02-20 2016-02-24 瑟阿瓦斯克公司 亚硝酸盐的药物制剂及其用途
US10517817B2 (en) 2013-05-09 2019-12-31 Syk Technologies, Llc Deep topical systemic nitric oxide therapy apparatus and method
WO2017132275A1 (en) 2016-01-27 2017-08-03 Syk Technologies, Llc Nitric oxide topical application apparatus and methods
KR20200083974A (ko) * 2017-09-05 2020-07-09 엑셀 메드, 엘엘씨 허혈 치료용 헤파린 조성물
WO2020141546A1 (en) 2019-01-02 2020-07-09 Celagenex Research (India) Pvt. Ltd. Synergistic nutritional compositions for pain management
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CN107260756A (zh) * 2009-10-14 2017-10-20 瑟阿瓦斯克有限公司 亚硝酸盐/酯的药物制剂以及其应用
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060182815A1 (en) * 2004-07-09 2006-08-17 Use of nitrite salts for the treatment of cardiovascular conditions

Also Published As

Publication number Publication date
JP2014139255A (ja) 2014-07-31
CN101939014A (zh) 2011-01-05
JP5908527B2 (ja) 2016-04-26
US10864229B2 (en) 2020-12-15
US20110311653A1 (en) 2011-12-22
IL205720A0 (en) 2010-11-30
IL205720A (en) 2015-08-31
WO2009065142A2 (en) 2009-05-22
JP5795165B2 (ja) 2015-10-14
JP2011503212A (ja) 2011-01-27
AU2008322437B2 (en) 2013-11-07
EP2219657A4 (en) 2020-01-08
EP2219657A2 (en) 2010-08-25
US20170312310A1 (en) 2017-11-02
AU2008322437A1 (en) 2009-05-22
US9649334B2 (en) 2017-05-16

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