CN101926891B - Composition for losing weight - Google Patents
Composition for losing weight Download PDFInfo
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- CN101926891B CN101926891B CN201010217255A CN201010217255A CN101926891B CN 101926891 B CN101926891 B CN 101926891B CN 201010217255 A CN201010217255 A CN 201010217255A CN 201010217255 A CN201010217255 A CN 201010217255A CN 101926891 B CN101926891 B CN 101926891B
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Abstract
The invention provides a composition for losing weight. The composition consists of a formula A and a formula B, wherein the formula A comprises the following raw materials in part by weight: 5 to 50 parts of capsaicin, 10 to 100 parts of guarana extract, 10 to 100 parts of green tea extract and 100 to 1,000 parts of lotus leaf extract; and the formula B comprises the following raw materials in part by weight: 100 to 1,000 parts of chitin and 100 to 1,000 parts of white kidney bean extract. The formula A of the composition for losing weight can accelerate the metabolism of a body and improve the burnt calories of the body; and the formula B can inhibit a human body from absorbing starch and fatty foods, and can effectively reduce the intake of energy under the condition of not controlling diet.
Description
Technical field
The present invention relates to a kind of health promoting product, specifically, relate to a kind of composition and method of making the same that is used to lose weight.
Background technology
Obesity is that energy take in to surpass energy expenditure and causes body fat to gather too much reaching a kind of chronic metabolic disease of the extent of injury.At present, China has overweight or nearly 300,000,000 people of overweight people, and wherein adult overweight or fat ratio reaches 22.8% and 7.1% respectively more than 18 years old.Along with the raising of health perception, increasing people recognize that obesity has become the very important able-bodied risk factor of serious threat people.
At present, the fat-reducing article on the market comprise appetrol and slimming health food, though the fat-reducing effect of appetrol is more obvious, it is big that ubiquity side effect, the shortcoming that drug dependence is strong.Though and slimming health food does not exist side effect and dependency, fat-reducing effect is scarcely very obvious.
Therefore, the present invention provides a kind of Weight reducing compound, through the body metabolism rate being provided and reducing human body to the absorption of starch food products with fat, accelerates body fat consumption, reaches the effect of rapid fat-reducing.
Summary of the invention
The purpose of this invention is to provide a kind of compositions that is used to lose weight,, accelerate body fat consumption, reach the effect of rapid fat-reducing through the body metabolism rate being provided and reducing the absorption of human body to starch and fat food.
Another object of the present invention provides the method for preparing of this Weight reducing compound.
In order to realize the object of the invention, a kind of compositions that is used to lose weight provided by the invention is made up of A, two prescriptions of B, and wherein the A prescription comprises the raw material of following weight portion:
Capsaicin 5-50 part,
Guarana extract 10-100 part,
Green tea extract 10-100 part,
Folium Nelumbinis extract 100-1000 part;
The B prescription comprises the raw material of following weight portion:
Chitin 100-1000 part,
Semen Phaseoli Vulgaris extract 100-1000 part.
Wherein, preferably, the A prescription comprises the raw material of following weight portion:
Capsaicin 5-20 part,
Guarana extract 10-50 part,
Green tea extract 10-50 part,
Folium Nelumbinis extract 500-1000 part;
The B prescription comprises the raw material of following weight portion:
Chitin 100-600 part,
Semen Phaseoli Vulgaris extract 100-600 part.
A prescription of the present invention also comprises 10-1000 part excipient, preferably 10-100 part.
The B prescription also comprises 5-500 part excipient, preferably 5-50 part.
The most preferred weight portion raw material of the compositions A prescription that is used for losing weight of the present invention is:
10 parts of capsaicin,
20 parts of Guarana extracts,
10 parts of green tea extracts,
900 parts of Folium Nelumbinis extracts,
50 parts of excipient.
The most preferred weight portion raw material of B prescription is:
400 parts of chitins,
390 parts of Semen Phaseoli Vulgaris extract,
10 parts of excipient.
Weight portion of the present invention can be the known content units of field of medicaments such as μ g, mg, g, kg.
Said excipient is selected from one or more in starch, dextrin, Pulvis Talci, cane sugar powder, ethanol, microcrystalline Cellulose, lactose, hydroxypropyl methylcellulose (HPMC), sodium carboxymethyl cellulose (CMS-Na), magnesium stearate and the micropowder silica gel.
The method for compositions that preparation the present invention is used to lose weight, the A prescription takes by weighing capsaicin, Guarana extract, green tea extract, Folium Nelumbinis extract raw material by proportioning, sieves, mixing, subsequent use; Add excipient then and process the preparation of various dosage forms; The B prescription takes by weighing chitin, Semen Phaseoli Vulgaris extract raw material by proportioning, sieves, and mixing, subsequent use; Add excipient then and process the preparation of various dosage forms.
Such as, in the preparation process, add pharmaceutically acceptable excipient, process various preparations according to the conventional method of this area.
The present invention adopts traditional preparation process technology to can be made into clinical acceptable any dosage form, like tablet, pill, capsule, granule etc.
The preparation of the various dosage forms of the present invention can adopt conventional method in the art to prepare.
Various raw materials involved in the present invention all can commercially availablely obtain.
Green tea extract, Folium Nelumbinis extract, Guarana extract and Semen Phaseoli Vulgaris extract are carried to good with water.
Preparation combined set meal of the present invention has following beneficial effect:
The compositions that is used to lose weight of the present invention; Be made up of A, two kinds of prescriptions of B, wherein the A prescription carries out capsaicin, green tea extract, Guarana extract, Folium Nelumbinis extract compositely by special ratios, is rich in natural caffeine; Can effectively improve body metabolism, and improve the ability of calory burning; B prescription Semen Phaseoli Vulgaris extract can suppress alpha amylase activity; Make it can't cut off starch, most starch, excretes through digestive system with complete molecular conformation; Thereby suppress amylolysis, absorb and be converted into fat, the heat that the blocking-up absorption of human body produces from starch food; The positively charged alkalescence of chitin is amino, around negative charge fat, constructs one deck barrier, and fatty oil droplet can not be digested, absorb by body, and is excreted.The B prescription can suppress human body starch and fat food are absorbed, and under the situation of not keeping on a diet, effectively reduces the absorption of energy.
The specific embodiment
Following examples are used to explain the present invention, but are not used for limiting scope of the present invention.
Various raw materials involved in the present invention all can commercially availablely obtain; Capsaicin is plain from the natural capsicum that sky, Tianjin uniting and adjustment flavor Products Co., Ltd produces, and (water is carried for green tea extract (water is carried, 90% polyphenol) and Folium Nelumbinis extract; Withdrawal ratio 10: 1) plants science and technology limited Company between exhaust from Guilin; Guarana extract (water is carried, 10% caffeine) from the illustrious and influential bio tech ltd in Dalian, (Semen Phaseoli Vulgaris extract is carried by water; Withdrawal ratio 10: 1) from Shanxi Jiahe Plant Chemical Co., Ltd., chitin is from Shanghai sharp system biochemical product company limited.
Embodiment 1
The preparation of Weight reducing compound capsule of the present invention:
The A prescription:
Choose raw material capsaicin, green tea extract, Guarana extract, Folium Nelumbinis extract and sieve respectively, choose the raw material that material is combined as for the preparation preparation under 40 mesh sieves.
Take by weighing following raw material respectively: capsaicin 5g, Guarana extract 100g, green tea extract 10g, Folium Nelumbinis extract 1000g, magnesium stearate 10g; Then material is mixed by weight the ascending equal-volume of approaching component, stir, pour capsule into and fill in the mould; The fill capsule; Polishing, packing promptly gets.
The B prescription:
Choose the raw material chitin, Semen Phaseoli Vulgaris extract sieves respectively, chooses the raw material that material under 40 mesh sieves is combined as for the preparation preparation.
Take by weighing following raw material respectively: chitin 100g, Semen Phaseoli Vulgaris extract 1000g, Pulvis Talci 50g, then material is mixed by weight the ascending equal-volume of approaching component, stir; Pour capsule into and fill in the mould, fill capsule, polishing; Packing promptly gets.
Embodiment 2
The preparation of Weight reducing compound granule of the present invention:
The A prescription:
Choose raw material capsaicin, green tea extract, Guarana extract, Folium Nelumbinis extract and sieve respectively, choose the raw material that material is combined as for the preparation preparation under 40 mesh sieves.
Take by weighing following raw material respectively: capsaicin 50g, Guarana extract 10g, green tea extract 100g, Folium Nelumbinis extract 100g, cane sugar powder 200g, then material is mixed by weight the ascending equal-volume of approaching component, stir; Use 50% ethanol as binding agent, the system soft material is processed granule with above-mentioned soft material through waving of 14 eye mesh screens in the granulator; Granule is inserted in the multi-functional boiling drier; About 40 minutes of 50 ℃ of airpillow-dry, control pellet moisture be 5%, then granulate; Packing promptly gets.
The B prescription:
Choose the raw material chitin, Semen Phaseoli Vulgaris extract sieves respectively, chooses the raw material that material under 40 mesh sieves is combined as for the preparation preparation.
Take by weighing following raw material respectively: chitin 1000g, Semen Phaseoli Vulgaris extract 100g, white sand Icing Sugar 500g, then material is mixed by weight the ascending equal-volume of approaching component, stir; Use 50% ethanol as binding agent, the system soft material is processed granule with above-mentioned soft material through waving of 14 eye mesh screens in the granulator; Granule is inserted in the multi-functional boiling drier, about 40 minutes of 50 ℃ of airpillow-dry, the control pellet moisture is 5%; Granulate then, packing promptly gets.
Embodiment 3
The preparation of Weight reducing compound tablet of the present invention:
The A prescription:
Choose raw material capsaicin, green tea extract, Guarana extract, Folium Nelumbinis extract and sieve respectively, choose the raw material that material is combined as for the preparation preparation under 40 mesh sieves.
Take by weighing following raw material respectively: capsaicin 5g, Guarana extract 50g, green tea extract 10g, Folium Nelumbinis extract 500g, lactose 100g, microcrystalline Cellulose 50g, then material is mixed by weight the ascending equal-volume of approaching component, stir, use 50% ethanol as binding agent; The system soft material is processed granule with above-mentioned soft material through waving of 14 eye mesh screens in the granulator, granule is inserted in the multi-functional boiling drier; About 40 minutes of 50 ℃ of airpillow-dry, control pellet moisture be 5%, granulate; In granule, add a small amount of magnesium stearate and micropowder silica gel then, total mixed, tabletting; The bag film-coat, packing promptly gets.
The B prescription:
Choose the raw material chitin, Semen Phaseoli Vulgaris extract sieves respectively, chooses the raw material that material under 40 mesh sieves is combined as for the preparation preparation.
Take by weighing following raw material respectively: chitin 100g, Semen Phaseoli Vulgaris extract 600g, starch 100g, then material is mixed by weight the ascending equal-volume of approaching component, stir, use 30% ethanol as binding agent; The system soft material is processed granule with above-mentioned soft material through waving of 14 eye mesh screens in the granulator, granule is inserted in the multi-functional boiling drier; About 40 minutes of 50 ℃ of airpillow-dry, control pellet moisture be 5%, then granulate; In granule, add a small amount of magnesium stearate and micropowder silica gel then, total mixed, tabletting; The bag film-coat, packing promptly gets.
Embodiment 4
The preparation of Weight reducing compound pill of the present invention:
The A prescription:
Choose raw material capsaicin, green tea extract, Guarana extract, Folium Nelumbinis extract and sieve respectively, choose the raw material that material is combined as for the preparation preparation under 40 mesh sieves.
Take by weighing following raw material respectively: capsaicin 20g, Guarana extract 10g, green tea extract 50g, Folium Nelumbinis extract 1000g, cane sugar powder 100g, then material is mixed by weight the ascending equal-volume of approaching component, stir; The aqueous solution that uses 0.8% sodium carboxymethyl cellulose is as binding agent; The system soft material is put into the pellet processing machine pill with above-mentioned soft material, oven dry; Packing behind the whole ball promptly gets.
The B prescription:
Choose the raw material chitin, Semen Phaseoli Vulgaris extract sieves respectively, chooses the raw material that material under 40 mesh sieves is combined as for the preparation preparation.
Take by weighing following raw material respectively: chitin 600g, Semen Phaseoli Vulgaris extract 100g, cane sugar powder 50g, then material is mixed by weight the ascending equal-volume of approaching component, stir; The aqueous solution that uses 0.8% sodium carboxymethyl cellulose is as binding agent; The system soft material is put into the pellet processing machine pill with above-mentioned soft material, oven dry; Packing behind the whole ball promptly gets.
Embodiment 5
Basically with embodiment 1, the component of different is capsule of the present invention is:
A prescription: capsaicin 10g, Guarana extract 20g, green tea extract 10g, Folium Nelumbinis extract 900g, lactose 40g, magnesium stearate 10g.
B prescription: chitin 400g, Semen Phaseoli Vulgaris extract 390g, magnesium stearate 10g.
Embodiment 6
Basically with embodiment 3, the component of different is tablet of the present invention is:
A prescription: capsaicin 15g, Guarana extract 30g, green tea extract 15g, Folium Nelumbinis extract 600g, lactose 80g, microcrystalline Cellulose 80g, magnesium stearate 6g.
B prescription: chitin 200g, Semen Phaseoli Vulgaris extract 500g, lactose 50g, magnesium stearate 7g.
Embodiment 7
Basically with embodiment 2, the component of different is granule of the present invention is:
A prescription: capsaicin 5g, Guarana extract 10g, green tea extract 10g, Folium Nelumbinis extract 500g, cane sugar powder 100g.
B prescription: chitin 100g, Semen Phaseoli Vulgaris extract 100g, lactose 50g.
Experimental example 1 human experimentation
1 experimental subject and method
1.1 experimental subject
This is tested whole experimenters and before experiment, carries out constitutional index assessment respectively and be obese people, male 9 examples among the 21 routine experimenters, women 12 examples; Age is between 21-55 year, year mean age (33.7 ± 8.5);
1.2 experimental technique
Divide into groups: 21 experimenters are divided into three groups at random, negative control group (N=7), positive controls (N=7) and experimental group (N=7).Negative control group is taken placebo, 5/day; Positive controls is taken 5/day of L-carnitine capsules, and experimental group is taken 5/day of fat-reducing composite capsule groups of the present invention (embodiment 5) (take 3 A prescriptions daytime, take 2 B prescriptions evening), takes for 4 weeks continuously.Whole experimental session is not kept on a diet, and does not painstakingly increase motion, and prohibits other diet food of clothes and medicine.
1.3 test index
1.3.1 body composition test: adopt the body weight of DX200 super strong type body composition test appearance test subject before the experiment and after the experiment weekly, body fat percentage, body-mass index.
1.4 data statistics
The gained data are handled with Excel, adopt single blind method and t check that test data is carried out statistical analysis, represent with mean ± SD.
2 experimental results and analysis
2.1 body composition analysis result
2.1.1 subject re-detection result before and after the experiment
Experimenter's body weight situation of change before and after table 1 experiment
Significant difference (P＜0.05) is arranged before and after * taking
Can find out by table 1, compare body weight before negative control group, positive controls and experimental group are tested the back and tested and all decrease, but the amplitude of experimental group weight loss be greater than positive controls and negative control group.
2.1.2 body fat percentage testing result before and after the experiment
Table 2 experimenter body fat percentage testing result
Significant difference (P＜0.05) is arranged before and after * taking
Can be found out that by table 2 compare not variation of body fat percentage after the negative control group experiment with before the experiment, positive controls slightly rises, the experimental group significance descends.
2.1.3 experiment front and rear body body mass index result
Table 3 experimenter body-mass index result
Significant difference (P＜0.05) is arranged before and after * taking
Can find out by table 3, compare body-mass index before negative control group, positive controls and experimental group are tested the back and tested and all decrease, descend but experimental group is significance.
2.2 take the slimming capsule subjective feeling
Obvious adverse reaction does not all appear during all experimenters take.There is 1 experimenter the symptom of anorexia, constipation to occur, takes the above transference cure in 1 week back at the initial stage of taking medicine.
3 discuss and conclusion
3.1 discuss
Obesity is a kind of multifactor chronic metabolic disease that causes, has become the common and multiple disease of current society.The basic principle of preventing and treating obesity is the negative balance state that is in caloric intake and consumption that human body is continued for a long time, reduces promptly that heat is taken in, the increase heat exhaustion.
Weight reducing compound of the present invention is by two types of different component compatibilities, and wherein the A prescription can quicken body metabolism, and improves the ability of calory burning; The B prescription can suppress human body starch and fat food are absorbed, and under the situation of not keeping on a diet, can effectively reduce the absorption of energy.In this experiment; Experimental group is compared with matched group, and the amplitude of losing weight is greater than positive controls and negative control group, and body fat percentage is significance and descends; Explain that the experimenter takes fat-reducing thing of the present invention in weight reduction; The also oxidized decomposition of part fat in the body, body fat percentage descends, and then improves body-mass index.
The present invention is through detecting, and has the slimming while equally for the Weight reducing compound of other embodiment of different prescriptions, reduces body weight percentage ratio, improves body-mass index.
Though, the present invention has been done detailed description in the preceding text with general explanation and specific embodiments, on basis of the present invention, can to some modifications of do or improvement, this will be apparent to those skilled in the art.Therefore, these modifications or the improvement on the basis of not departing from spirit of the present invention, made all belong to the scope that requirement of the present invention is protected.
Claims (9)
1. a compositions that is used to lose weight is characterized in that, is made up of A, two prescriptions of B, and the A prescription is processed by the raw material of following weight portion:
Capsaicin 5-50 part,
Guarana extract 10-100 part,
Green tea extract 10-100 part,
Folium Nelumbinis extract 100-1000 part;
The B prescription is processed by the raw material of following weight portion:
Chitin 100-1000 part,
Semen Phaseoli Vulgaris extract 100-1000 part.
2. compositions according to claim 1 is made up of A, two prescriptions of B, it is characterized in that the A prescription is processed by the raw material of following weight portion:
Capsaicin 5-20 part,
Guarana extract 10-50 part,
Green tea extract 10-50 part,
Folium Nelumbinis extract 500-1000 part;
The B prescription is processed by the raw material of following weight portion:
Chitin 100-600 part,
Semen Phaseoli Vulgaris extract 100-600 part.
3. a compositions that is used to lose weight is characterized in that, is made up of A, two prescriptions of B, and the A prescription is processed by the raw material of following weight portion:
Capsaicin 5-50 part,
Guarana extract 10-100 part,
Green tea extract 10-100 part,
Folium Nelumbinis extract 100-1000 part,
Excipient 10-1000 part;
The B prescription is processed by the raw material of following weight portion:
Chitin 100-1000 part,
Semen Phaseoli Vulgaris extract 100-1000 part,
Excipient 5-500 part.
4. compositions according to claim 3 is characterized in that, excipient is 10-100 part in the A prescription, and excipient is 5-50 part in the B prescription.
5. compositions according to claim 4 is characterized in that, the A prescription is processed by the raw material of following weight portion:
10 parts of capsaicin,
20 parts of Guarana extracts,
10 parts of green tea extracts,
900 parts of Folium Nelumbinis extracts,
50 parts of excipient;
The B prescription is processed by the raw material of following weight portion:
400 parts of chitins,
390 parts of Semen Phaseoli Vulgaris extract,
10 parts of excipient.
6. compositions according to claim 3; It is characterized in that said excipient is selected from one or more in starch, dextrin, Pulvis Talci, cane sugar powder, ethanol, microcrystalline Cellulose, lactose, hydroxypropyl methylcellulose, sodium carboxymethyl cellulose, magnesium stearate and the micropowder silica gel.
7. according to claim 4 or 5 described compositionss; It is characterized in that said excipient is selected from one or more in starch, dextrin, Pulvis Talci, cane sugar powder, ethanol, microcrystalline Cellulose, lactose, hydroxypropyl methylcellulose, sodium carboxymethyl cellulose, magnesium stearate and the micropowder silica gel.
8. compositions according to claim 1 is characterized in that, the dosage form of said A, two prescriptions of B is respectively tablet, pill, capsule or granule.
9. each said method for compositions of preparation claim 1-8 is characterized in that the A prescription takes by weighing capsaicin, Guarana extract, green tea extract, Folium Nelumbinis extract raw material by proportioning, sieve, and mixing, subsequent use; Process tablet, pill, capsule or granule; The B prescription takes by weighing chitin, Semen Phaseoli Vulgaris extract raw material by proportioning, sieves, and mixing, subsequent use; Process tablet, pill, capsule or granule.
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| CN201010217255A CN101926891B (en) | 2010-06-23 | 2010-06-23 | Composition for losing weight |
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| CN201010217255A CN101926891B (en) | 2010-06-23 | 2010-06-23 | Composition for losing weight |
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| CN101926891A CN101926891A (en) | 2010-12-29 |
| CN101926891B true CN101926891B (en) | 2012-10-10 |
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Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103230021B (en) * | 2012-08-10 | 2014-06-18 | 广州市赛健生物科技有限公司 | Weight-loss health-care food and preparation method thereof |
| CN104397697A (en) * | 2014-12-02 | 2015-03-11 | 张满锦 | Weight-losing guarana oral liquid |
| CN104664406A (en) * | 2015-03-03 | 2015-06-03 | 深圳市妍倩科技有限公司 | Safe and healthy food with weight losing function |
| CN105641215A (en) * | 2016-01-13 | 2016-06-08 | 时代生物科技（深圳）有限公司 | Health product composition with weight-reducing effect and preparation method thereof |
| CN105685995B (en) * | 2016-02-15 | 2018-10-26 | 北京同仁堂健康药业股份有限公司 | A kind of composition of weight-reducing |
| CN105747222A (en) * | 2016-03-17 | 2016-07-13 | 天津元恒德科技有限公司 | Composition having effects of lowering blood fat and reducing weight and application |
| CN111034999A (en) * | 2019-12-31 | 2020-04-21 | 北京康比特体育科技股份有限公司 | Composition with sugar-resisting and weight-losing functions |
| CN112450385A (en) * | 2020-12-02 | 2021-03-09 | 宣城柏维力生物工程有限公司 | Preparation process of white kidney bean hull sugar direct drinking powder |
| CN114632101B (en) * | 2022-03-10 | 2022-10-11 | 广东省科学院微生物研究所(广东省微生物分析检测中心) | Cordyceps guangdongensis weight-losing lipid-lowering liver-protecting compound and preparation method and application thereof |
| CN115428949B (en) * | 2022-07-08 | 2024-02-06 | 江中药业股份有限公司 | Probiotic traditional Chinese medicine composition with weight-losing function and preparation method thereof |
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| WO1999029332A1 (en) * | 1997-12-08 | 1999-06-17 | Natural Medico Tech A/S | Compositions for weight reduction |
| CN1701675A (en) * | 2005-06-10 | 2005-11-30 | 张晶 | Fat-reducing candy |
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