CN101910416A - 在癌症患者中诊断性使用的方法和组合物 - Google Patents

在癌症患者中诊断性使用的方法和组合物 Download PDF

Info

Publication number
CN101910416A
CN101910416A CN2008801243215A CN200880124321A CN101910416A CN 101910416 A CN101910416 A CN 101910416A CN 2008801243215 A CN2008801243215 A CN 2008801243215A CN 200880124321 A CN200880124321 A CN 200880124321A CN 101910416 A CN101910416 A CN 101910416A
Authority
CN
China
Prior art keywords
patient
genes
cancer
therapy
vegf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2008801243215A
Other languages
English (en)
Chinese (zh)
Inventor
丹尼尔·S·陈
珍妮弗·勒库特
托马斯·D·吴
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of CN101910416A publication Critical patent/CN101910416A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medical Treatment And Welfare Office Work (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN2008801243215A 2007-11-09 2008-11-05 在癌症患者中诊断性使用的方法和组合物 Pending CN101910416A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US98688407P 2007-11-09 2007-11-09
US60/986,884 2007-11-09
PCT/US2008/082456 WO2009061800A2 (en) 2007-11-09 2008-11-05 Methods and compositions for diagnostic use in cancer patients

Publications (1)

Publication Number Publication Date
CN101910416A true CN101910416A (zh) 2010-12-08

Family

ID=40342593

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2008801243215A Pending CN101910416A (zh) 2007-11-09 2008-11-05 在癌症患者中诊断性使用的方法和组合物

Country Status (13)

Country Link
US (2) US20090123930A1 (enExample)
EP (1) EP2222874A2 (enExample)
JP (1) JP2011502513A (enExample)
KR (1) KR20100095571A (enExample)
CN (1) CN101910416A (enExample)
AU (1) AU2008324782A1 (enExample)
BR (1) BRPI0817158A2 (enExample)
CA (1) CA2703258A1 (enExample)
IL (1) IL205246A0 (enExample)
MX (1) MX2010005057A (enExample)
RU (1) RU2010123381A (enExample)
WO (1) WO2009061800A2 (enExample)
ZA (1) ZA201002808B (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104364655A (zh) * 2012-06-26 2015-02-18 霍夫曼-拉罗奇有限公司 贝伐单抗组合疗法用于治疗乳腺癌的血浆生物标志物
CN106164296A (zh) * 2014-02-07 2016-11-23 阿尔玛克诊断有限公司 用于预测对抗血管生成药的应答和癌症预后的分子诊断测试
CN107109700A (zh) * 2014-12-09 2017-08-29 默沙东公司 用于推导对pd‑1拮抗剂的反应的基因特征生物标志物的系统和方法
WO2025098320A1 (en) * 2023-11-09 2025-05-15 Sun Jet Biotechnology Inc. Alpha-1 antitrypsin biomarkers for detecting and monitoring cancers

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG177640A1 (en) * 2009-07-13 2012-02-28 Genentech Inc Diagnostic methods and compositions for treatment of cancer
US20110064732A1 (en) * 2009-09-17 2011-03-17 Sanne Lysbet De Haas Methods and compositions for diagnostic use in cancer patients
WO2012010549A1 (en) * 2010-07-19 2012-01-26 F. Hoffmann-La Roche Ag Method to identify a patient with an increased likelihood of responding to an anti-cancer therapy
SG187121A1 (en) * 2010-07-19 2013-02-28 Hoffmann La Roche Method to identify a patient with an increased likelihood of responding to an anti-cancer therapy
CA2838086A1 (en) 2011-06-02 2012-12-06 Almac Diagnostics Limited Molecular diagnostic test for cancer
MX356802B (es) * 2012-01-13 2018-06-13 Genentech Inc Marcadores biologicos para identificar pacientes para tratamiento con antagonistas de vegf.
WO2014087156A1 (en) * 2012-12-03 2014-06-12 Almac Diagnostics Limited Molecular diagnostic test for cancer
US11015190B2 (en) 2013-09-17 2021-05-25 Lucence Life Sciences Pte Ltd Method of treating a patient having renal cancer
KR101903522B1 (ko) * 2015-11-25 2018-11-23 한국전자통신연구원 다차원 건강데이터에 대한 유사사례 검색 방법 및 그 장치

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030027216A1 (en) * 2001-07-02 2003-02-06 Kiernan Urban A. Analysis of proteins from biological fluids using mass spectrometric immunoassay
WO2006108659A2 (en) * 2005-04-13 2006-10-19 Oncotest Gmbh Gene expression profiles being predictive for the response of tumors to pharmaceutically effective compounds
EP2002264A2 (en) * 2006-03-31 2008-12-17 Bayer HealthCare LLC Methods for prediction and prognosis of cancer, and monitoring cancer therapy

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104364655A (zh) * 2012-06-26 2015-02-18 霍夫曼-拉罗奇有限公司 贝伐单抗组合疗法用于治疗乳腺癌的血浆生物标志物
CN106164296A (zh) * 2014-02-07 2016-11-23 阿尔玛克诊断有限公司 用于预测对抗血管生成药的应答和癌症预后的分子诊断测试
CN107109700A (zh) * 2014-12-09 2017-08-29 默沙东公司 用于推导对pd‑1拮抗剂的反应的基因特征生物标志物的系统和方法
WO2025098320A1 (en) * 2023-11-09 2025-05-15 Sun Jet Biotechnology Inc. Alpha-1 antitrypsin biomarkers for detecting and monitoring cancers

Also Published As

Publication number Publication date
IL205246A0 (en) 2010-12-30
US20110151468A1 (en) 2011-06-23
EP2222874A2 (en) 2010-09-01
AU2008324782A1 (en) 2009-05-14
BRPI0817158A2 (pt) 2015-04-14
CA2703258A1 (en) 2009-05-14
WO2009061800A2 (en) 2009-05-14
WO2009061800A3 (en) 2009-07-16
JP2011502513A (ja) 2011-01-27
RU2010123381A (ru) 2011-12-20
MX2010005057A (es) 2010-05-19
US20090123930A1 (en) 2009-05-14
ZA201002808B (en) 2011-07-27
KR20100095571A (ko) 2010-08-31

Similar Documents

Publication Publication Date Title
US20230220491A1 (en) Therapeutic, diagnostic, and prognostic methods for cancer
CN102265157B (zh) 用于癌症患者中诊断用途的方法和组合物
CN101910416A (zh) 在癌症患者中诊断性使用的方法和组合物
US20100029491A1 (en) Methods and compositions for diagnostic use for tumor treatment
CN102612566B (zh) 用于癌症患者中诊断学用途的方法和组合物
BR112017012553B1 (pt) Método de tratamento de um paciente que sofre de um câncer, método para o diagnóstico de um câncer, método para o prognóstico de um paciente que sofre de câncer, método para determinar se um paciente com um câncer e método para otimizar a eficácia terapêutica de uma terapia anticâncer

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20101208