CN101897395A - Multiparous galactagogue feed additive for pigs and production method thereof - Google Patents
Multiparous galactagogue feed additive for pigs and production method thereof Download PDFInfo
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- CN101897395A CN101897395A CN201010172019.6A CN201010172019A CN101897395A CN 101897395 A CN101897395 A CN 101897395A CN 201010172019 A CN201010172019 A CN 201010172019A CN 101897395 A CN101897395 A CN 101897395A
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- galactagogue
- multiparous
- pigs
- feed additive
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- 239000003674 animal food additive Substances 0.000 title claims abstract description 19
- 239000005467 galactogogue Substances 0.000 title claims abstract description 19
- 241000282887 Suidae Species 0.000 title claims abstract description 18
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 13
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 42
- 239000004475 Arginine Substances 0.000 claims abstract description 21
- 229930003427 Vitamin E Natural products 0.000 claims abstract description 21
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims abstract description 21
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims abstract description 21
- 229940046009 vitamin E Drugs 0.000 claims abstract description 21
- 235000019165 vitamin E Nutrition 0.000 claims abstract description 21
- 239000011709 vitamin E Substances 0.000 claims abstract description 21
- YNGDWRXWKFWCJY-UHFFFAOYSA-N 1,4-Dihydropyridine Chemical compound C1C=CNC=C1 YNGDWRXWKFWCJY-UHFFFAOYSA-N 0.000 claims abstract description 16
- CJWQYWQDLBZGPD-UHFFFAOYSA-N isoflavone Natural products C1=C(OC)C(OC)=CC(OC)=C1C1=COC2=C(C=CC(C)(C)O3)C3=C(OC)C=C2C1=O CJWQYWQDLBZGPD-UHFFFAOYSA-N 0.000 claims abstract description 16
- 235000008696 isoflavones Nutrition 0.000 claims abstract description 16
- BVTBRVFYZUCAKH-UHFFFAOYSA-L disodium selenite Chemical compound [Na+].[Na+].[O-][Se]([O-])=O BVTBRVFYZUCAKH-UHFFFAOYSA-L 0.000 claims abstract description 15
- 229960001471 sodium selenite Drugs 0.000 claims abstract description 15
- 235000015921 sodium selenite Nutrition 0.000 claims abstract description 15
- 239000011781 sodium selenite Substances 0.000 claims abstract description 15
- 238000012856 packing Methods 0.000 claims abstract description 4
- 150000002515 isoflavone derivatives Chemical class 0.000 claims description 15
- 239000000203 mixture Substances 0.000 claims description 12
- 239000002994 raw material Substances 0.000 claims description 9
- 229920002261 Corn starch Polymers 0.000 claims description 8
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 8
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims description 8
- 239000008120 corn starch Substances 0.000 claims description 8
- 229940099112 cornstarch Drugs 0.000 claims description 8
- 239000008103 glucose Substances 0.000 claims description 8
- 239000000843 powder Substances 0.000 claims description 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 4
- 238000007689 inspection Methods 0.000 claims description 3
- 238000005303 weighing Methods 0.000 claims description 3
- 229910021536 Zeolite Inorganic materials 0.000 claims description 2
- 239000000440 bentonite Substances 0.000 claims description 2
- 229910000278 bentonite Inorganic materials 0.000 claims description 2
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 claims description 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims description 2
- 229940036811 bone meal Drugs 0.000 claims description 2
- 239000002374 bone meal Substances 0.000 claims description 2
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 claims description 2
- 239000011780 sodium chloride Substances 0.000 claims description 2
- 239000010457 zeolite Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 10
- 235000016709 nutrition Nutrition 0.000 abstract description 7
- 230000001850 reproductive effect Effects 0.000 abstract description 7
- 229940088597 hormone Drugs 0.000 abstract description 6
- 239000005556 hormone Substances 0.000 abstract description 6
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- 238000000034 method Methods 0.000 abstract description 2
- 235000003170 nutritional factors Nutrition 0.000 abstract 2
- GOMNOOKGLZYEJT-UHFFFAOYSA-N isoflavone Chemical compound C=1OC2=CC=CC=C2C(=O)C=1C1=CC=CC=C1 GOMNOOKGLZYEJT-UHFFFAOYSA-N 0.000 abstract 1
- 230000003248 secreting effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 230000002195 synergetic effect Effects 0.000 abstract 1
- 229940126680 traditional chinese medicines Drugs 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 description 8
- 230000036039 immunity Effects 0.000 description 5
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- 239000000654 additive Substances 0.000 description 3
- 230000000996 additive effect Effects 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 230000035558 fertility Effects 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 239000008267 milk Substances 0.000 description 3
- 235000013336 milk Nutrition 0.000 description 3
- 210000004080 milk Anatomy 0.000 description 3
- 210000002966 serum Anatomy 0.000 description 3
- 102000012673 Follicle Stimulating Hormone Human genes 0.000 description 2
- 108010079345 Follicle Stimulating Hormone Proteins 0.000 description 2
- 108010051696 Growth Hormone Proteins 0.000 description 2
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 description 2
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 description 2
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 2
- 102000013275 Somatomedins Human genes 0.000 description 2
- 102100038803 Somatotropin Human genes 0.000 description 2
- 229960003121 arginine Drugs 0.000 description 2
- 235000009697 arginine Nutrition 0.000 description 2
- 238000009395 breeding Methods 0.000 description 2
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- 235000013601 eggs Nutrition 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 210000003754 fetus Anatomy 0.000 description 2
- 229940028334 follicle stimulating hormone Drugs 0.000 description 2
- 239000000122 growth hormone Substances 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 230000016087 ovulation Effects 0.000 description 2
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- 230000001105 regulatory effect Effects 0.000 description 2
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- 229910052711 selenium Inorganic materials 0.000 description 2
- 239000011669 selenium Substances 0.000 description 2
- 229940091258 selenium supplement Drugs 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 1
- 102000004452 Arginase Human genes 0.000 description 1
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- 241000588724 Escherichia coli Species 0.000 description 1
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- 208000019395 Lactation disease Diseases 0.000 description 1
- 102000003946 Prolactin Human genes 0.000 description 1
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- 206010042576 Suppressed lactation Diseases 0.000 description 1
- AUYYCJSJGJYCDS-LBPRGKRZSA-N Thyrolar Chemical class IC1=CC(C[C@H](N)C(O)=O)=CC(I)=C1OC1=CC=C(O)C(I)=C1 AUYYCJSJGJYCDS-LBPRGKRZSA-N 0.000 description 1
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Abstract
The invention relates to a multiparous galactagogue feed additive for pigs and a production method thereof. The multiparous galactagogue feed additive for the pigs is prepared from 10 to 30 weight percent of dihydropyridine, 1 to 10 weight percent of isoflavone, 1 to 5 weight percent of vitamin E, 1 to 2 weight percent of sodium selenite, 10 to 20 weight percent of arginine and the balance of carrier. The method comprises the following steps of: proportioning, mixing, packing, performing quality check and putting into storage. Nutritional factors which influence the reproductive performance of females can be directly added into the feed, so the secreting level of female sex gland hormones can be directly adjusted, various nutritional substances can be adjusted to be balanced, the formula is scientific, the nutrition is comprehensive, the nutritional requirement of the females in the reproduction period can be completely met, and the added nutritional factors have good synergistic effect. Compared with the products added with traditional Chinese medicines, the product of the invention has the obvious advantages of short onset time, exact curative effect, small addition amount and the like.
Description
Technical field
The present invention relates to a kind of feed addictive and production method thereof that improves the sow fertility rate and the output of milk.
Background technology
In the process that sow is cultured, the phenomenon of first farrowing sow galactosis deficiency in lactation appears through regular meeting, need in time adopt an effective measure, the sow of hypogalactia is carried out lactagogue.Therefore market in urgent need improves the product of the dam farrowing quantity and the output of milk.The raiser to the reproductive hormone class medicine of postpartum to the sow injection, though can effectively improve farrowing quantity, uses hormone medicine at insemination of sows for a long time, can cause the hormone residues in the meat, and human body is had very big toxic and side effect.And existing Chinese herbal medicine class feedstuff additive product complicated component, active constituent content is low, bioavailability is low, its market manifestation is that addition is big, onset slow, DeGrain, and the prescription of existing Chinese herbal medicine series products is all very complicated, the adding ingredient that has is kind surplus in the of 30 nearly, not only production method is loaded down with trivial details, also increase product cost, be difficult to carry out marketing.The most nutritional labelings of existing product need not excessive replenishing, and lack synergy between each composition, and assimilation effect is also bad.
Summary of the invention
The invention provides a kind of multiparous galactagogue feed additive for pigs and production method thereof, solve that the existing product onset is slow, effect is bad, and the technical problem of complicated component, complex production process.
The technical solution adopted for the present invention to solve the technical problems is:
This multiparous galactagogue feed additive for pigs is mixed by weight by following raw material,
Dihydropyridine 10%～30%;
Isoflavones 1%～10%;
Vitamin E 1%～5%;
Sodium selenite 1%～2%;
Arginine 10%～20%;
The carrier surplus.
This multiparous galactagogue feed additive for pigs is mixed by weight by following raw material,
Dihydropyridine 25%;
Isoflavones 8%;
Vitamin E 5%;
Sodium selenite 2%;
Arginine 15%;
The carrier surplus.
Described carrier can be wherein one or more the mixture of sodium acid carbonate, glucose, cornstarch, chaff cake powder, sodium chloride, bone meal, bentonite in powder, zeolite powder.
Described carrier can be the mixture of sodium acid carbonate, cornstarch and glucose.
The production method of this multiparous galactagogue feed additive for pigs, the carrier weighing by weight percentage of the dihydropyridine with 10%～30%, 1%～10% isoflavones, 1%～5% vitamin E, 1%～2% sodium selenite, 10%～20% arginine and surplus, mix, packing, quality inspection, warehouse-in.
Beneficial effect of the present invention is as follows:
Main component of the present invention is dihydropyridine, isoflavones, vitamin E, sodium selenite, arginine, is the trophic factors that natural animal-plant extracts, and has advantage safe, that have no side effect.
The present invention can directly regulate dam gonadal hormone secretion level by directly add the trophic factors that influences the female livestock breed performance in feed.Compare with the product that adds Chinese medicine, have remarkable advantages such as rapid-action, determined curative effect, addition are few.
The various nutriments of the multiple adjustment of the present invention, the prescription science, comprehensive nutrition can satisfy the nutritional need of dam breeding period fully.
The present invention has simplified the production technology of product, has reduced the production cost of additive.
Several trophic factors effects that the present invention added are as follows:
Dihydropyridine: some effect with natural VE, can improve important regulating and controllings such as thyroid hormone in the serum, follicle-stimulating hormone (FSH) element, metakentrin and produce hormonal readiness, thereby improve growth of animal, production (lay eggs, give milk) and reproductive performance, improve the animal product quality, and the content of immunodepressant cortisol in the reduction serum, promote the growth of lymphoid organ, strengthen function of immune system.Absorb by stomach and intestine in animal body through zoopery proof dihydropyridine, discharge with urine, seldom retain in other organ and tissue, belong to non-poisonous material, it is fool proof to feed.
Isoflavones: be from the refining bioactivator that forms of soybean, it is a kind of natural nutrition factor with multiple important physiologically active, there is estrogen-like effect to reduce the ovarian follicle atrophy, promote ovulation, can have the immunity of organisms of enhancing, improve animal reproduction power and physiological actions such as secretion capacity and promotion growth of animal.
Vitamin E: can keep the normal reproduction function of pig, and Wheat Protein, improve immune level, strengthen resistance to Escherichia coli, virosis.The effect that vitamin E also has anti-heat stress, improves immunity and fertility of sow.
Sodium selenite: the biological function of selenium and vitamin E is similar and synergy is arranged, and has very strong antioxidation.The sodium selenite of higher concentration can promote the proliferation activity of cell DNA, delaying cell aging.
Arginine: arginine can induce hypophysis to discharge prolactin and growth hormone is very important to sow reproductive performance.Type-1 insulin like growth factor (IGF-1) level raises after giving arginine.And growth hormone is to the ovulation of animal with reduce the death of embryonated egg and lose facilitation is arranged.Arginic in addition many metabolic pathways, thereby provide foundation much to be confirmed: by adding exogenous arginine in the daily ration for improving sow reproductive performance, can make arginine concentration rising in the sow blood plasma, thereby strengthen immunity and the anti-stress ability of sow self, guarantee the stability of environment in the placenta, increase embryo's implantation and minimizing embryo's death.And arginic concentration increases in the blood plasma, just has more arginine and is used for the fetus synthetic protein, can guarantee that the growth of fetus body tissue has sufficient raw material sources, improves the survival rate of piglet.
Above several trophic factors that the present invention adds have good mutual synergy, can bring into play regulating action from different perspectives, and common the interpolation has better result of use.Isoflavones is a kind female hormone, and natural having no side effect can be improved the serum estrogen level in the body; Vitamin E belongs to anti-oxidant series products, can remove interior free yl, improve immunity, it is hyperfunction that the while vitamin E can be urged the sexual gland secretory cell, promote to promote the concentration of animal female hormone in health, acting synergistically with isoflavones has the effect of better raising fecundity.The effectiveness of selenium and vitamin E collocation can raising vitamin E; Dihydropyridine can partly substitute vitamin E and use, and can reduce cost.The also special arginine that adds of the present invention, arginine is a kind of important amino acid in the growth of animal phase, additional arginine has multiple functions such as the immunity of raising, promotion growth.
The present invention is producing omnidistance the interpolation, and addition is that feed per ton adds 1000 grams.Below be of the influence experiment of pig multiparous galactagogue feed additive to newborn piglet litter weight and average individual weight.
Newborn piglet litter weight and average individual weight (kg/ head)
Show by above-mentioned result of the test, use this additive can impel dam to reach good figure, promote reproductive development, oestrus performance obviously, and breeding time is concentrated and in advance, can be improved litter size and number of weaned, reduce nonpregnant rate and difficult labour rate, effectively improved the reproductive performance of dam.
The specific embodiment
Embodiment one, and this multiparous galactagogue feed additive for pigs is mixed by weight by following raw material,
Dihydropyridine 25%;
Isoflavones 8%;
Vitamin E 5%;
Sodium selenite 2%;
Arginine 15%;
The carrier surplus.
Carrier adopts the mixture of sodium acid carbonate, cornstarch and glucose.
Embodiment two, and this multiparous galactagogue feed additive for pigs is mixed by weight by following raw material,
Dihydropyridine 15%;
Isoflavones 5%;
Vitamin E 2%;
Sodium selenite 1%;
Arginine 13%;
The carrier surplus.
Carrier adopts the mixture of sodium acid carbonate, cornstarch and glucose.
Embodiment three, and this multiparous galactagogue feed additive for pigs is mixed by weight by following raw material,
Dihydropyridine 30%;
Isoflavones 8%;
Vitamin E 1%;
Sodium selenite 2%;
Arginase 12 0%;
The carrier surplus.
Carrier adopts the mixture of sodium acid carbonate, cornstarch and glucose.
Embodiment four, and this multiparous galactagogue feed additive for pigs is mixed by weight by following raw material,
Dihydropyridine 10%;
Isoflavones 5%;
Vitamin E 5%;
Sodium selenite 1%;
Arginine 10%;
The carrier surplus.
Carrier adopts the mixture of sodium acid carbonate, cornstarch and glucose.
The production method of multiparous galactagogue feed additive for pigs is in the foregoing description, with the carrier weighing by weight percentage of dihydropyridine, isoflavones, vitamin E, sodium selenite, arginine and surplus, mix, packing, quality inspection, warehouse-in.
Claims (5)
1. multiparous galactagogue feed additive for pigs is characterized in that: mixes by weight by following raw material,
Dihydropyridine 10%～30%;
Isoflavones 1%～10%;
Vitamin E 1%～5%;
Sodium selenite 1%～2%;
Arginine 10%～20%;
The carrier surplus.
2. multiparous galactagogue feed additive for pigs according to claim 1 is characterized in that: mixed dihydropyridine 25% by weight by following raw material;
Isoflavones 8%;
Vitamin E 5%;
Sodium selenite 2%;
Arginine 15%;
The carrier surplus.
3. multiparous galactagogue feed additive for pigs according to claim 1 is characterized in that: described carrier is wherein one or more the mixture of sodium acid carbonate, glucose, cornstarch, chaff cake powder, sodium chloride, bone meal, bentonite in powder, zeolite powder.
4. multiparous galactagogue feed additive for pigs according to claim 3 is characterized in that: described carrier is the mixture of sodium acid carbonate, cornstarch and glucose.
5. the production method of a multiparous galactagogue feed additive for pigs is characterized in that: the carrier weighing by weight percentage of the dihydropyridine with 10%～30%, 1%～10% isoflavones, 1%～5% vitamin E, 1%～2% sodium selenite, 10%～20% arginine and surplus, mix, packing, quality inspection, warehouse-in.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102239973A (en) * | 2011-08-15 | 2011-11-16 | 赣州八维生物科技有限公司 | Additive used for nursing sows, preparation process and using method thereof |
| CN103829084A (en) * | 2013-12-17 | 2014-06-04 | 四川农业大学 | Feed additive capable of promoting mammary gland development of replacement gilts and gestating sows |
| CN104872419A (en) * | 2015-05-15 | 2015-09-02 | 上海交通大学 | Anti-oxidative stress nutritional composition for breeding sows and preparation method of anti-oxidative stress nutritional composition for breeding sows |
| CN108783072A (en) * | 2018-06-26 | 2018-11-13 | 安徽鲜森绿色食品有限公司 | Improve the feed of laying hen egg yield, the preparation process and its feeding method of feed |
| CN109380616A (en) * | 2017-08-14 | 2019-02-26 | 河南爱诺生物科技有限公司 | A kind of feed addictive and preparation method thereof for improving sows farrowing ability and improving lactation amount |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101214012B (en) * | 2008-01-02 | 2011-10-19 | 大连中植环境生物科技有限公司 | Cow concentrated feed confected by hybridization Chinese holley leaf |
-
2010
- 2010-05-14 CN CN201010172019.6A patent/CN101897395B/en active Active
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102239973A (en) * | 2011-08-15 | 2011-11-16 | 赣州八维生物科技有限公司 | Additive used for nursing sows, preparation process and using method thereof |
| CN103829084A (en) * | 2013-12-17 | 2014-06-04 | 四川农业大学 | Feed additive capable of promoting mammary gland development of replacement gilts and gestating sows |
| CN103829084B (en) * | 2013-12-17 | 2015-10-28 | 四川农业大学 | A kind of feed addictive promoting standby and in-pig mammogenesis |
| CN104872419A (en) * | 2015-05-15 | 2015-09-02 | 上海交通大学 | Anti-oxidative stress nutritional composition for breeding sows and preparation method of anti-oxidative stress nutritional composition for breeding sows |
| CN109380616A (en) * | 2017-08-14 | 2019-02-26 | 河南爱诺生物科技有限公司 | A kind of feed addictive and preparation method thereof for improving sows farrowing ability and improving lactation amount |
| CN108783072A (en) * | 2018-06-26 | 2018-11-13 | 安徽鲜森绿色食品有限公司 | Improve the feed of laying hen egg yield, the preparation process and its feeding method of feed |
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