CN101883848A - 具有蛋白酶活性的多肽和编码该多肽的多核苷酸 - Google Patents

具有蛋白酶活性的多肽和编码该多肽的多核苷酸 Download PDF

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Publication number
CN101883848A
CN101883848A CN2008801187450A CN200880118745A CN101883848A CN 101883848 A CN101883848 A CN 101883848A CN 2008801187450 A CN2008801187450 A CN 2008801187450A CN 200880118745 A CN200880118745 A CN 200880118745A CN 101883848 A CN101883848 A CN 101883848A
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China
Prior art keywords
polypeptide
sequence
cell
protein
enzyme
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Pending
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CN2008801187450A
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English (en)
Chinese (zh)
Inventor
宇田川裕晃
克里斯琴·I·乔根森
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Novo Nordisk AS
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Novo Nordisk AS
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Publication of CN101883848A publication Critical patent/CN101883848A/zh
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C12N9/62Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from Aspergillus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN2008801187450A 2007-10-01 2008-09-30 具有蛋白酶活性的多肽和编码该多肽的多核苷酸 Pending CN101883848A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07117588 2007-10-01
EP07117588.9 2007-10-01
PCT/EP2008/063102 WO2009043854A1 (en) 2007-10-01 2008-09-30 Polypeptides having protease activity and polynucleotides encoding same

Publications (1)

Publication Number Publication Date
CN101883848A true CN101883848A (zh) 2010-11-10

Family

ID=38645844

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2008801187450A Pending CN101883848A (zh) 2007-10-01 2008-09-30 具有蛋白酶活性的多肽和编码该多肽的多核苷酸

Country Status (5)

Country Link
US (3) US8383391B2 (enExample)
EP (1) EP2201110A1 (enExample)
JP (1) JP2010539964A (enExample)
CN (1) CN101883848A (enExample)
WO (1) WO2009043854A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140147895A1 (en) 2011-07-22 2014-05-29 Novozymes A/S Processes for Pretreating Cellulosic Material and Improving Hydrolysis Thereof
CN104024408B (zh) * 2011-12-28 2019-04-19 诺维信公司 具有蛋白酶活性的多肽

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE68924654T2 (de) 1988-01-07 1996-04-04 Novonordisk As Spezifische Protease.
DK52393D0 (enExample) 1993-05-05 1993-05-05 Novo Nordisk As
JP4263241B2 (ja) 1996-03-27 2009-05-13 ノボザイムス アクティーゼルスカブ アルカリプロテアーゼを欠失した糸状真菌
ATE313620T1 (de) * 1996-09-19 2006-01-15 Novozymes As Wirtszellen und methoden für die produktion von proteinen
IL133134A0 (en) * 1999-11-25 2001-03-19 American Israeli Paper Mills Improved paper products
US7208310B2 (en) * 2003-06-19 2007-04-24 Novozymes A/S Proteases
WO2004113551A1 (en) 2003-06-25 2004-12-29 Novozymes A/S Process for the hydrolysis of starch
DK2333045T3 (en) 2005-04-12 2017-02-20 Danisco Us Inc GEN-INACTIVATED MUTANTS WITH CHANGED PROTEIN PRODUCTION
EP1941025B1 (en) * 2005-10-17 2011-06-29 Novozymes A/S Use of fungal mutants for expression of antibodies

Also Published As

Publication number Publication date
US20100304433A1 (en) 2010-12-02
JP2010539964A (ja) 2010-12-24
US8945879B2 (en) 2015-02-03
EP2201110A1 (en) 2010-06-30
US20140295493A1 (en) 2014-10-02
US8383391B2 (en) 2013-02-26
US20130122545A1 (en) 2013-05-16
WO2009043854A1 (en) 2009-04-09

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Application publication date: 20101110