CN101874853A - Pills for treating ulcerative colitis and preparation process thereof - Google Patents
Pills for treating ulcerative colitis and preparation process thereof Download PDFInfo
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- CN101874853A CN101874853A CN201010186781XA CN201010186781A CN101874853A CN 101874853 A CN101874853 A CN 101874853A CN 201010186781X A CN201010186781X A CN 201010186781XA CN 201010186781 A CN201010186781 A CN 201010186781A CN 101874853 A CN101874853 A CN 101874853A
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Abstract
The invention provides Chinese medicinal pills for treating ulcerative colitis, which are prepared by processing the following medicaments in part by weight: 9 to 11 parts of honeysuckle, 9 to 11 parts of mongolian dandelion herb, 9 to 11 parts of szechwon tangshen root, 7 to 9 parts of astragalus, 7 to 9 parts of Chinese angelica, 4 to 6 parts of liquorice root, 4 to 6 parts of weeping forsythia, 4 to 6 parts of catechu, 1 to 3 parts of mongolian snakegourd root, 1 to 3 parts of angelica dahurlica, 1 to 3 parts of chicken's gizzard-membrane, 2 to 4 parts of charred rehmanniae praeparatum and 2 to 4 parts of charred largetrifoliolious bugbane rhizome. Aiming at symptoms such as ulcerative colitis, hypofunction of the spleen and the stomach and endoretention of damp heat, the pills have the effects of tonifying the spleen and qi, clearing away heat and toxic materials, cooling blood and hemostasis and stopping diarrhea, and the medicaments are selected and combined according to the method. The Chinese medicinal pills have the advantages of definite curative effect, no side effect, safety and reliability.
Description
Technical field:
The invention belongs to the Chinese medicine preparation technical field, be specifically related to a kind of medicine pill and preparation method for the treatment of ulcerative colitis.
Background technology:
Ulcerative colitis (UC) is one of main hazard factor of colon tumor generation, and its sickness rate is in rising trend, to become the emphasis of digestive system disease research.The canceration rate of colitis is higher 5～20 times than the normal person, and the sickness rate of colon cancer has leapt to the 3rd in cancer at present, and the whole world has 1,000,000 people to be diagnosed as this disease every year approximately, nearly 500,000 people so and dead.Therefore, classified as one of modern difficult treatment by World Health Organization (WHO).The medicine modern medicine is mainly used sulfonamides, immunosuppressant, adrenocortical hormone etc. at present, and side effect is many, and easily recurrence.The clinical symptoms performance is based on mucopurulent bloody stool, stomachache, diarrhoea or tenesmus; As untimely treatment, the concurrent acute ectocolon of meeting, perforated ulcer, colon cancer and intestinal obstruction etc. cause the mortality rate height.The difficult pertinacious disease of Chinese medicine has unique advantage, and the traditional Chinese medical science thinks that morbidity is is this with the weakness of the spleen and stomach, is due to the gastrointestinal dysfunction that rises of index with damp-heat accumulation, stagnation of blood stasis, belongs to the disease of deficiency in origin and excess in superficiality.Existing Chinese patent medicine exists dosage big, and the patient takes for a long time and is difficult to adhere to etc. shortcoming particularly lack determined curative effect, low toxicity, high-efficiency preparation.
Summary of the invention:
Technical problem to be solved by this invention is to address the above problem, and develops a kind of novel determined curative effect, low toxicity, treats the medicine pill of ulcerative colitis efficiently.
Said preparation is by Flos Lonicerae, Herba Taraxaci, Radix Codonopsis, the Radix Astragali, Radix Angelicae Sinensis, Radix Glycyrrhizae, Fructus Forsythiae, catechu, Radix Trichosanthis, the Radix Angelicae Dahuricae, Endothelium Corneum Gigeriae Galli, the medicine pill that fresh rehmannia charcoal, Rhizoma Cimicifugae charcoal process from strand.Its weight consists of: Flos Lonicerae 9-11 part, Herba Taraxaci 9-11 part, Radix Codonopsis 9-11 part, Radix Astragali 7-9 part, Radix Angelicae Sinensis 7-9 part, Radix Glycyrrhizae 4-6 part, catechu 4-6 part, Fructus Forsythiae 4-6 part, Radix Trichosanthis 1-3 part, Radix Angelicae Dahuricae 1-3 part, Endothelium Corneum Gigeriae Galli 1-3 part, fresh rehmannia charcoal 2-4 part, Rhizoma Cimicifugae charcoal 2-4 part.
The weight of said preparation is formed can be 10 parts of Flos Loniceraes, 10 parts of Herba Taraxacis, 10 parts of Radix Codonopsis, 8 parts of the Radixs Astragali, 8 parts of Radix Angelicae Sinensis, 5 parts in Radix Glycyrrhizae, 5 parts in catechu, 5 parts of Fructus Forsythiaes, 2 parts of Radix Trichosanthis, 2 parts of the Radixs Angelicae Dahuricae, 2 parts of Endothelium Corneum Gigeriae Galli, 3 parts of fresh rehmannia charcoals, 3 parts of Rhizoma Cimicifugae charcoals.
A kind of preparation method that is used for the treatment of the medicine pill of ulcerative colitis provided by the invention is: match well extracting honeysuckle, Herba Taraxaci, the Radix Astragali, Radix Glycyrrhizae, Fructus Forsythiae, catechu, Radix Trichosanthis mixing by weight, adding 10 times of water gagings extracts 3 times, each 2 hours, filter, filtrate decompression concentrates, be dried to extractum, pulverize, cross 100 mesh sieves; Get Radix Angelicae Sinensis, Radix Codonopsis, Endothelium Corneum Gigeriae Galli, the Radix Angelicae Dahuricae, fresh rehmannia charcoal, Rhizoma Cimicifugae charcoal pulverizing more by weight, cross 100 mesh sieves, wherein Endothelium Corneum Gigeriae Galli is pulverized the 60Co-radiation gamma processing of back with 6KGy; Mix above-mentioned powder, make pill with pellet processing machine.
Technical scheme of the present invention is according to theory of Chinese medical science, and insufficiency of the spleen leading to overabundance of dampness is the key factor that causes ulcerative colitis to take place.Exopathogenic factor and damp and hot relation are maximum, and damp is invaded, impairing the spleen and stomach, dysfunction of the spleen in transportation and transformation, so-called " domination of damp bringing about watery diarrhea.In the damp and hot obstruction intestinal, the QI and blood knot of fighting mutually with it makes intestinal conduction mistake department, and venation is injured, coagulation of QI-blood, corruption turn to pus and blood and under the dysentery red in vain; The mechanism of qi retardance, FU QI being obstructed is then suffered from abdominal pain, tenesmus.Endogenous cause of ill is then close with insufficiency of the spleen relation, insufficiency of the spleen mistake fortune, and indigestion is precise and tiny, and endogenous damp formation mixes and descends.Insufficiency of the spleen mistake fortune can cause wet the Sheng, and the latter can influence the fortuneization of spleen again, insufficiency of the spleen and wetly contains the reciprocal causation that influences each other.Therefore, ulcerative colitis is to be this with the weakness of the spleen and stomach, is the gastrointestinal dysfunction that index rises with damp-heat accumulation, stagnation of blood stasis, belongs to the disease of deficiency in origin and excess in superficiality, belongs to sick categories such as the traditional Chinese medical science is had loose bowels, dysentery.
This prescription founds the method for invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, cooling blood for hemostasis, antidiarrheal, and selects the medicine prescription accordingly at ulcerative colitis weakness of the spleen and stomach, retention of damp-heat in the interior card.
With Radix Codonopsis, Radix Astragali the kidney invigorating gas, replenishing QI and blood, spleen invigorating and in, inspire healthy energy with anti-evil, be usefulness with Herba Taraxaci, Flos Lonicerae mutual reinforcement between, removing summer-heat gastrointestinal pyretic toxicity is combined into monarch drug.Get Fructus Forsythiae, catechu, Radix Trichosanthis, heat-clearing and toxic substances removing, cooling blood for hemostasis, skin ulcer is held back in detumescence, and " removing chronic heat in the intestines and stomach ", the Radix Rehmanniae, Rhizoma Cimicifugae are got charcoal for using, be intended to strengthen the merit of cooling blood for hemostasis, dysentery relieving, when division " all pains of trusted subordinate ", Endothelium Corneum Gigeriae Galli then " eliminating dampness by diuresis heresy " to end " dysentery "; Radix Angelicae Dahuricae detumescence and apocenosis and pain relieving, Radix Glycyrrhizae eliminating fire and detoxication, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, the duty of department's messenger drug.All 13 flavors in full side are eliminating evilly taken into account with setting upright, and stress eliminating evilly, and the cold temperature of medicine is usefulness mutually, do not have eliminating evil wound just, set upright the anxiety of loving heresy.All medicines match well, and play the effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, cooling blood for hemostasis, antidiarrheal altogether.Be used for having loose bowels due to weakness of the spleen and stomach, the retention of damp-heat in the interior, disease is seen diarrhoea, bloody purulent stool, stomachache, tenesmus, burning sensation of the anus, dark coloured urine, red tongue with yellowish and greasy fur, slippery and rapid pulse; Ulcerative colitis is seen above-mentioned patient.
The present invention has following advantage: (1) determined curative effect; (2) have no side effect.
The specific embodiment:
Embodiment 1:
Flos Lonicerae 10g, Herba Taraxaci 10g, Radix Codonopsis 10g, Radix Astragali 8g, Radix Angelicae Sinensis 8g, Radix Glycyrrhizae 5g, Fructus Forsythiae 5g, catechu 5g, Radix Trichosanthis 2g, Radix Angelicae Dahuricae 2g, Endothelium Corneum Gigeriae Galli 2g, fresh rehmannia charcoal 3g, Rhizoma Cimicifugae charcoal 3g.
Match well extracting honeysuckle, Herba Taraxaci, the Radix Astragali, Radix Glycyrrhizae, Fructus Forsythiae, catechu, Radix Trichosanthis by weight and mix, adds 10 times of water gagings and extract 3 times, each 2 hours, filter, filtrate decompression concentrates, and is dried to extractum, pulverize, 100 mesh sieves; Get Radix Angelicae Sinensis, Radix Codonopsis, Endothelium Corneum Gigeriae Galli, the Radix Angelicae Dahuricae, fresh rehmannia charcoal, Rhizoma Cimicifugae charcoal pulverizing more by weight, cross 100 mesh sieves, wherein Endothelium Corneum Gigeriae Galli is pulverized the 60Co-radiation gamma processing of back with 6KGy; Mix above-mentioned powder, make pill with pellet processing machine.Per 100 balls nearly weigh 6g.
Instructions of taking: every day twice, each 2-4g.
Embodiment 2:
Flos Lonicerae 9g, Herba Taraxaci 11g, Radix Codonopsis 10g, Radix Astragali 7g, Radix Angelicae Sinensis 7g, Radix Glycyrrhizae 6g, Fructus Forsythiae 4g, catechu 6g, Radix Trichosanthis 1g, Radix Angelicae Dahuricae 1g, Endothelium Corneum Gigeriae Galli 1g, fresh rehmannia charcoal 2g, Rhizoma Cimicifugae charcoal 2g.
Preparation method is with embodiment 1.
Instructions of taking: every day twice, each 2-4g.
Embodiment 3:
Flos Lonicerae 11g, Herba Taraxaci 11g, Radix Codonopsis 9g, Radix Astragali 9g, Radix Angelicae Sinensis 9g, Radix Glycyrrhizae 4g, Fructus Forsythiae 6g, catechu 4g, Radix Trichosanthis 3g, Radix Angelicae Dahuricae 3g, Endothelium Corneum Gigeriae Galli 3g, fresh rehmannia charcoal 4g, Rhizoma Cimicifugae charcoal 4g.
Preparation method is with embodiment 1.
Instructions of taking: every day twice, each 2-4g.
Embodiment 4: clinical trial
Model case 1:
Week XX, the man, 50 years old, existing 4 years ulcerative colitis medical histories were taken our embodiment 1 pill one month, fully recovered.
Model case 2:
Liu XX, the woman, 31 years old, suffer from 5 years medical histories of chronic ulcerative colitis, take our embodiment 5 weeks of 1 pill, fully recover.
Typical case 3:
Zhao XX, the man, 60 years old, suffer from 8 years medical histories of ulcerative colitis, took our embodiment 1 two months, fully recover.
Typical case 4:
King XX, the man, 40 years old, suffer from 4 years medical histories of ulcerative colitis, take our embodiment 5 weeks of 2 pills, fully recover.
Typical case 5:
Open XX, the man, 52 years old, suffer from 7 years medical histories of ulcerative colitis, take our embodiment 9 weeks of 2 pills, fully recover.
Typical case 6:
Lee XX, the woman, 32 years old, suffer from 3 years medical histories of ulcerative colitis, take our embodiment 4 weeks of 3 pills, fully recover.
Typical case 7:
Grandson XX, the man, 68 years old, suffer from 8 years medical histories of ulcerative colitis, take our embodiment 10 weeks of 3 pills, fully recover.
Claims (3)
1. pill for the treatment of ulcerative colitis is characterized in that: it is that preparation of raw material by the following weight component forms: Flos Lonicerae 9-11 part, Herba Taraxaci 9-11 part, Radix Codonopsis 9-11 part, Radix Astragali 7-9 part, Radix Angelicae Sinensis 7-9 part, Radix Glycyrrhizae 4-6 part, catechu 4-6 part, Fructus Forsythiae 4-6 part, Radix Trichosanthis 1-3 part, Radix Angelicae Dahuricae 1-3 part, Endothelium Corneum Gigeriae Galli 1-3 part, fresh rehmannia charcoal 2-4 part, Rhizoma Cimicifugae charcoal 2-4 part.
2. a kind of pill for the treatment of ulcerative colitis according to claim 1 is characterized in that: it is that preparation of raw material by the following weight component forms: 10 parts of Flos Loniceraes, 10 parts of Herba Taraxacis, 10 parts of Radix Codonopsis, 8 parts of the Radixs Astragali, 8 parts of Radix Angelicae Sinensis, 5 parts in Radix Glycyrrhizae, 5 parts in catechu, 5 parts of Fructus Forsythiaes, 2 parts of Radix Trichosanthis, 2 parts of the Radixs Angelicae Dahuricae, 2 parts of Endothelium Corneum Gigeriae Galli, 3 parts of fresh rehmannia charcoals, 3 parts of Rhizoma Cimicifugae charcoals.
3. a kind of preparation method for the treatment of the pill of ulcerative colitis as claimed in claim 1 is characterized in that: this pill is that the raw material with select carries out screening, cleans oven dry; Match well extracting honeysuckle, Herba Taraxaci, the Radix Astragali, Radix Glycyrrhizae, Fructus Forsythiae, catechu, Radix Trichosanthis by weight and mix, adds 10 times of water gagings and extract 3 times, each 2 hours, filter, filtrate decompression concentrates, and is dried to extractum, pulverize, 100 mesh sieves; Get Radix Angelicae Sinensis, Radix Codonopsis, Endothelium Corneum Gigeriae Galli, the Radix Angelicae Dahuricae, fresh rehmannia charcoal, Rhizoma Cimicifugae charcoal pulverizing more by weight, cross 100 mesh sieves, wherein Endothelium Corneum Gigeriae Galli is pulverized the 60Co-radiation gamma processing of back with 6KGy; Raw material after the reuse mixer sieves mixes, and makes medicine pill with pellet processing machine then.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010186781.XA CN101874853B (en) | 2010-05-31 | 2010-05-31 | Pills for treating ulcerative colitis and preparation process thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010186781.XA CN101874853B (en) | 2010-05-31 | 2010-05-31 | Pills for treating ulcerative colitis and preparation process thereof |
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| Publication Number | Publication Date |
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| CN101874853A true CN101874853A (en) | 2010-11-03 |
| CN101874853B CN101874853B (en) | 2014-01-22 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201010186781.XA Active CN101874853B (en) | 2010-05-31 | 2010-05-31 | Pills for treating ulcerative colitis and preparation process thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103705646A (en) * | 2013-12-29 | 2014-04-09 | 刘俊英 | Traditional Chinese medicine enema for treating ulcerative colitis |
| CN103800597A (en) * | 2014-02-24 | 2014-05-21 | 王洋 | Traditional Chinese medicine for treating damp-heat accumulation ulcerative colitis |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1428165A (en) * | 2001-12-28 | 2003-07-09 | 北京中惠药业有限公司 | Chinese medicine positioning preparation for curing ulcerative colitis |
| CN1857453A (en) * | 2006-03-03 | 2006-11-08 | 延边大学 | Chinese medicine composition for treating ulcerative colitis and its preparing method |
-
2010
- 2010-05-31 CN CN201010186781.XA patent/CN101874853B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1428165A (en) * | 2001-12-28 | 2003-07-09 | 北京中惠药业有限公司 | Chinese medicine positioning preparation for curing ulcerative colitis |
| CN1857453A (en) * | 2006-03-03 | 2006-11-08 | 延边大学 | Chinese medicine composition for treating ulcerative colitis and its preparing method |
Non-Patent Citations (2)
| Title |
|---|
| 刘进等: "溃疡性结肠炎中医综合疗法概况", 《世界中西医结合杂志》 * |
| 田振国等: "通腑宁颗粒治疗结肠炎性疾病解析", 《中国中医药现代远程教育》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103705646A (en) * | 2013-12-29 | 2014-04-09 | 刘俊英 | Traditional Chinese medicine enema for treating ulcerative colitis |
| CN103705646B (en) * | 2013-12-29 | 2016-08-17 | 齐达春 | A kind of Chinese medicinal enema treating ulcerative colitis |
| CN103800597A (en) * | 2014-02-24 | 2014-05-21 | 王洋 | Traditional Chinese medicine for treating damp-heat accumulation ulcerative colitis |
| CN103800597B (en) * | 2014-02-24 | 2016-07-06 | 杜翠云 | A kind of Chinese medicine treating retention of damp-heat in the interior type ulcerative colitis |
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| Publication number | Publication date |
|---|---|
| CN101874853B (en) | 2014-01-22 |
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