CN101869654A

CN101869654A - Chinese medicinal pills for treating scrofula

Info

Publication number: CN101869654A
Application number: CN 201010199219
Authority: CN
Inventors: 孔凡玉; 孔国平
Original assignee: Individual
Current assignee: Individual
Priority date: 2010-06-12
Filing date: 2010-06-12
Publication date: 2010-10-27
Anticipated expiration: 2030-06-12
Also published as: CN101869654B

Abstract

The invention relates to Chinese medicinal pills for treating scrofula, which solve the problems of poor curative effect, large administration dose and easy relapse in the treatment of the scrofula effectively. The Chinese medicinal pills adopt the technical scheme by comprising the following steps of: mixing gansui root, mongolian dandelion herb, weeping forsythia and unibract fritillary bulb serving as raw material medicaments in a weight ratio of 50:2:0.5:0.5 uniformly; adding water in an amount which is 7 to 8 times that of the raw material medicaments, and decocting the raw material medicaments for 3 to 4 hours for filtering to obtain filter liquor; and concentrating the filter liquor until the filter liquor is changed into thick paste like flakes when picked by a rod, standing and cooling the thick paste, and preparing the thick paste into pills. The Chinese medicinal pills can be used for treating the scrofula effectively, and have the advantages of high absorption of medicaments, quick response, high bioavailability, good treatment effect and convenient carrying and administration.

Description

The scrofulous medicine pill of a kind of treatment

One, technical field

The present invention relates to field of medicaments, the scrofulous medicine pill of particularly a kind of treatment.

Two, background technology

Lymphoid tuberculosis is a kind of commonly encountered diseases, and pilosity is born in cervical region, by the caused lymph node chronic inflammation of mycobacterium tuberculosis infection.This disease is often involved a plurality of lymph nodes, comes across the cervical region one or both sides, chin down or sternocleidomastoid front and rear edge and the dark face of muscle be predilection site.Clinical manifestation, the initial stage lymphadenectasis, hardening can be isolated activity, has the small number of patients local skin to be reddish violet, and is shinny, or slight pain is arranged, along with the progress of the course of disease, the pathological changes lymphadenectasis, agglomerating with surrounding tissue adhesion or inter-adhesive bunchiness.Later stage also can be downright bad, forms abscess or ulceration and become chronic ulcer or sinus tract, flows out cheesy thin pus.Sometimes can be with systemic toxic symptoms, as: low grade fever, night sweat, asthenia, anorexia is become thin, anemia etc.The lymph node of enlargement is generally not red not bitterly, so claim " cold abscess ", the traditional Chinese medical science is called " scrofula ", is commonly called as " scrofula ".At present for scrofulous treatment, the one, operative treatment, two are to use antibiotic medicine, operative treatment exists postoperative and causes that easily tuberculosis of skin infects, behind the tuberculosis infection skin, the drug level of changing dressings of outside routine is difficult to reach, and flushing is just glanced off, external world's contact of wound causes the infection of other antibacterials unavoidably.Antibiotic medicine is not good to scrofulous therapeutic effect, although new drug constantly comes out, but do not reduce scrofulous sickness rate and relapse rate, tubercule bacillus has drug resistance, the antibiotic of long-term low concentration impels the Production by Bacteria different drug resistance that changes, when environment is unfavorable for growth and breeding and existence, conventional bacterium can be changed into " L " bacterium (sensitive organism), the bacteria wall defectiveness has the effect of hiding body and medicine, when body immunity descends, " L " but the reversion of type bacterium, recover that it is pathogenic, recurrence once more is though there is the scrofulous Chinese medicine of treatment now, but bioavailability is low, dose is big, and curative effect is also unsatisfactory, is expected by many so develop the scrofulous medicine of a kind of effective treatment.

Three, summary of the invention

At above-mentioned situation, for overcoming the prior art defective, the present invention's purpose just provides the scrofulous medicine pill of a kind of treatment, can effectively solve scrofulous treatment weak curative effect, and dose is big, easily the problem of recurrence.

The technical scheme that the present invention solves is, by the Radix Kansui with weight ratio: Herba Taraxaci: Fructus Forsythiae: Bulbus Fritillariae Cirrhosae is 50: 2: 0.5: 0.5 makes as material medicine, with Radix Kansui, Herba Taraxaci, Fructus Forsythiae, Bulbus Fritillariae Cirrhosae mixing, add material medicine weight and 7-8 times of water gaging, decocted 3-4 hour, filter, get filtrate, be concentrated into rod and provoke the thick paste that falls in the form of sheets, cool pill.

The present invention also can directly make powder when producing, decoction or oral liquid formulation, and the present invention can be effective to treat lymphoid tuberculosis, and drug absorption is good, instant effect, the bioavailability height, therapeutic effect is good, and is easy to carry and use.

Four, the specific embodiment

Below in conjunction with embodiment the specific embodiment of the present invention is elaborated.

Embodiment 1:

In the specific implementation, the present invention also can be made as material medicine by Radix Kansui 25kg, Herba Taraxaci 1kg, Fructus Forsythiae 0.25kg, Bulbus Fritillariae Cirrhosae 0.25kg, with Radix Kansui, Herba Taraxaci, Fructus Forsythiae, Bulbus Fritillariae Cirrhosae mixing, add 200kg water, decocted 3 hours, filter, get filtrate, be concentrated into rod and provoke the thick paste that falls in the form of sheets, cool, pill, every ball 0.6g.

Embodiment 2:

The present invention also can be made as material medicine by Radix Kansui 50kg, Herba Taraxaci 2kg, Fructus Forsythiae 0.5kg, Bulbus Fritillariae Cirrhosae 0.5kg, with Radix Kansui, Herba Taraxaci, Fructus Forsythiae, Bulbus Fritillariae Cirrhosae mixing, add 424kg water, decocted 4 hours, and filtered, get filtrate, be concentrated into rod and provoke the thick paste that falls in the form of sheets, cool pill, every ball 0.6g.

Embodiment 3:

The present invention also can be made as material medicine by Radix Kansui 37.5kg, Herba Taraxaci 1.5kg, Fructus Forsythiae 0.375kg, Bulbus Fritillariae Cirrhosae 0.375kg, with Radix Kansui, Herba Taraxaci, Fructus Forsythiae, Bulbus Fritillariae Cirrhosae mixing, add 300kg water, decocted 3.5 hours, and filtered, get filtrate, be concentrated into rod and provoke the thick paste that falls in the form of sheets, cool pill, every ball 0.6g.

Said medicine, wherein:

Radix Kansui: choose decontamination, water rinses, and pulls out, dries, and has removing water retention by purgation by expectorant, the effect of dispersing swelling and dissipating binds, and all herbal medicine is used for the treatment of various edema, hydrothorax, ascites, defecation is unfavorable, epilepsy abundant expectoration, carbuncle sore tumefacting virus etc.;

Herba Taraxaci: choose decontamination, clean earth, cutting is dried, and all herbal medicine is used for the treatment of mastitis, conjunctivitis, lymphadenitis, furuncle carbuncle toxin, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, urinary tract infection etc.;

Fructus Forsythiae: choose clean impurity, stranding is opened, and removes discarding stalk, has heat-clearing and toxic substances removing, and the dispelling wind and heat pathogens effect has the title of " persons particularly liable to develop skin infection's panacea ".Control warm, erysipelas, macule, the carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction, clearing away heart-fire;

Bulbus Fritillariae Cirrhosae: another name Bulbus Fritillariae Cirrhosae, choose decontamination, water steeps slightly, pulls out, and moistening is peelled off the heart, dries, and has removing heat-phlegm, and the effect of lung moistening eliminating stagnation is controlled cough due to consumptive disease, the spitting of blood of spitting, ambition pent-up, consumptive lung disease, lung abscess, goiter, scrofula, sore throat, acute mastitis etc.

The scientific combination of said medicine supports each other that on function have heat-clearing and toxic substances removing, the effect of dispersing swelling and dissipating binds is effectively treated lymphoid tuberculosis, and ingredient is stable, is beneficial to drug absorption, and is proved fully through clinical, and relevant clinical data is as follows:

One, case choice criteria

All lymphadenitises that is diagnosed as, lymphoid tuberculosis, and to meet tcm diagnosis be scrofula, popular name " scrofula " person.

Two, diagnostic criteria

(1) neck sidepiece lymphadenectasis, nodositas, painless.Be more common in child and youth.

(2) initial stage is solitary tubercle, and is more smooth, movable, is fused into piece with posterior tubercle, and irregular, mobility is poor.Lump can form abscess, and fluctuation is arranged, and can form sinus tract behind the ulceration, moves under water with the skin bottom, does not prolongedly heal.

(3) secretions is thin, often contains cheesy thing, and the wound surface granulation is unhealthy.

(4) low grade fever, night sweat, weak, General Symptoms such as become thin can be arranged.

(5) some patient can have tuberculosis medical history or pathological changes such as pulmonary.

(6) get pathological tissues and carry out the PCR detection, the result is positive.

(7) pathological biopsy can be clarified a diagnosis.

Every possess all can making a definite diagnosis that above-mentioned feature and biopsy make a definite diagnosis.

Three, therapeutic scheme

The oral medicine of the present invention of patient, once a day, one time one ball, every ball 0.6g, 15 days is a course of treatment, judges curative effect after 4 courses of treatment.

Four, efficacy assessment standard

Cure: wound healing, incrustation, the complete obiteration of lymphoid tuberculosis lump;

Produce effects: the lymphoid tuberculosis lump diminishes, and the open sore part begins the raw meat that heals, and low grade fever disappears;

Effectively: low grade fever alleviates, and effusive routed liquid also begins to reduce, and the lymphoid tuberculosis lump diminishes gradually;

Invalid: with the treatment before compare, symptom does not have improvement.

Five, statistical disposition

Among the 234 routine patients, the age minimum is 2 years old, is 30 years old to the maximum, the course of disease is the shortest to be 1 year, and the longest is 10 years, cures 200 examples, produce effects 20 examples, effective 10 examples, invalid 4 examples, total effective rate reaches more than 98%, and wherein, lymphoid tuberculosis is the ulceration person not, be 45 days for the full course of treatment, every day one ball, every ball 0.6g, the take medicine person that had the low grade fever in 2 days, low grade fever obviously disappears, and the lymphoid tuberculosis lump began to diminish in 4-7 days, low grade fever disappears, the complete obiteration of 10-20 days tuberculosis lumps, but still have sick cell not remove fully, continue and obeyed 25 days, rehabilitation, no longer recurrence, lymphoid tuberculosis ulceration person, every day one ball, every ball 0.6g, 60 days is the full course of treatment, takes medicine 2 days, and person's low grade fever alleviates the low grade fever, effusive routed liquid also begins to reduce, and the open sore part no longer flowed out routed liquid in 10-15 days, and the open sore part also diminishes many, and begin the raw meat that heals, incrustation was fallen the crust recovery from illness, was continued to take medicine 15 days again in 35-45 days, consolidate curative effect, do not recur after healing.Above patient has only example drug withdrawal midway, not treatment again, recurrence after a year, 4 examples are not cured, but evident in efficacy, and the ulceration wound healing no longer heals to the beans size, all there is not the untoward reaction of appearance, this medicine taboo: be not taken by pregnant women the anti-Radix Glycyrrhizae of Radix Kansui, the anti-Aconitum carmichjaelii Debx. of Bulbus Fritillariae Cirrhosae.

Six, conclusion

In sum, the present invention is scrofulous effective, the safe medicine pill of treatment, and total effective rate reaches more than 98%, ingredient is stable, the bioavailability height, and drug safety is convenient, clinical meaning is outstanding, and it is applied is of value to the healthy of people, and economic and social benefit is remarkable.

Claims

1. treat scrofulous medicine pill for one kind, it is characterized in that, by the Radix Kansui with weight ratio: Herba Taraxaci: Fructus Forsythiae: Bulbus Fritillariae Cirrhosae is 50: 2: 0.5: 0.5 makes as material medicine, with Radix Kansui, Herba Taraxaci, Fructus Forsythiae, Bulbus Fritillariae Cirrhosae mixing, add material medicine weight and 7-8 times of water gaging, decocted 3-4 hour, filter, get filtrate, be concentrated into rod and provoke the thick paste that falls in the form of sheets, cool pill.

2. the scrofulous medicine pill of treatment according to claim 1, it is characterized in that, make as material medicine, with Radix Kansui, Herba Taraxaci, Fructus Forsythiae, Bulbus Fritillariae Cirrhosae mixing by Radix Kansui 25kg, Herba Taraxaci 1kg, Fructus Forsythiae 0.25kg, Bulbus Fritillariae Cirrhosae 0.25kg, add 200kg water, decocted 3 hours, and filtered, get filtrate, be concentrated into rod and provoke the thick paste that falls in the form of sheets, cool pill, every ball 0.6g.

3. the scrofulous medicine pill of treatment according to claim 1, it is characterized in that, make as material medicine, with Radix Kansui, Herba Taraxaci, Fructus Forsythiae, Bulbus Fritillariae Cirrhosae mixing by Radix Kansui 50kg, Herba Taraxaci 2kg, Fructus Forsythiae 0.5kg, Bulbus Fritillariae Cirrhosae 0.5kg, add 424kg water, decocted 4 hours, and filtered, get filtrate, be concentrated into rod and provoke the thick paste that falls in the form of sheets, cool pill, every ball 0.6g.

4. the scrofulous medicine pill of treatment according to claim 1, it is characterized in that, make as material medicine, with Radix Kansui, Herba Taraxaci, Fructus Forsythiae, Bulbus Fritillariae Cirrhosae mixing by Radix Kansui 37.5kg, Herba Taraxaci 1.5kg, Fructus Forsythiae 0.375kg, Bulbus Fritillariae Cirrhosae 0.375kg, add 300kg water, decocted 3.5 hours, and filtered, get filtrate, be concentrated into rod and provoke the thick paste that falls in the form of sheets, cool pill, every ball 0.6g.