CN102772648B - Traditional Chinese medicine composition for curing oral ulcer - Google Patents

Abstract

The invention discloses a traditional Chinese medicine composition for curing oral ulcer, in particular to a traditional Chinese medicine preparation. The traditional Chinese medicine composition for curing oral ulcer is high in curative rate, rapid in curative effect and relapse-free. Oral ulcer is clinically and mainly pathologically characterized in that local mucosa epitheliums of oral cavities are dissolved, ruptured and shed so that nonspecific ulcer is formed. Therefore, the traditional Chinese medicine composition for curing oral ulcer is prepared into powder and selectively comprises hopleaf ampelopsis root-bark, purple loosestrife, honeysuckle, vietnamese sophora roots, purple actinidia, myrrh, natural indigo, gypsum, amur corktree bark, gardenia, cochinchnese asparagus roots, dwarf lilyturf roots, figwort roots, artificial bezoar, borax and musk which are capable of clearing heat, removing toxicity, diminishing inflammation, relieving pain, removing slough, promoting growth of tissue regeneration and enhancing immunity. According to clinical tests, the total effective rate reaches 98.6%, the curative effect is better than that of comparison groups, the traditional Chinese medicine composition for curing oral ulcer is rapid in curative effect and relapse-free, and the problem of high relapse rate of oral ulcer is well solved.

Description

A kind of Chinese medicine composition for the treatment of oral ulcer

Technical field

The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine preparation for the treatment of oral ulcer.

Background technology

Oral ulcer is a kind of stomatocace infringement of outbreak repeatedly, and the cause of disease is still not clear, is common oral disease clinically.Be the superficial ulcer occurring on oral mucosa, large I is from the grain of rice to Semen Glycines size, circular or oval, and ulcer surface is recessed, congested around, can cause pain because of irritable food, is apt to occur in the edge of oral mucosa and tongue,

Better to send out without keratinization or the poor position of keratinization, as positions such as Mucosa of lip, the tip of the tongue, lingual margin, tongue abdomen, soft palate and tonsils, relevant with factors such as infection, digestive functional disturbance, endocrine regulation, Nervous and Mental Factors, inherited genetic factors, trace element deficiency and wounds.Although a lot of to the Therapeutic Method of oral ulcer, be all symptomatic treatment substantially, alleviate slowly and easily recurrence.Popular method mainly contains gentamycin therapy, vitamin E therapy, YUNNAN BAIYAO therapy, BINGPENG SAN therapy etc. at present, but all has limitation separately.With regard to primary disease, its recurrent is an insoluble problem.

Summary of the invention

The object of this invention is to provide a kind of cure rate high, curative effect is fast, the Chinese medicine preparation of the treatment oral ulcer not recurring.The dialectical genus the liver failing to maintain the normal flow of QI of tcm clinical practice, flaming up of liver-fire.Clinical with the dissolving of oral cavity partial mucous epithelium, ulceration, come off, and form non-specific ulcer be main pathology.Chinese traditional treatment is taking heat-clearing and toxic substances removing, anti-inflammatory analgetic, putrefaction-removing granulation-promoting, raising immunity as the rule for the treatment of.

The object of the invention is to be achieved through the following technical solutions, the Chinese medicine composition of this treatment oral ulcer is made up of the Chinese medicine of following weight portion: Cortex Ampelopsis Humulifoliae Radicis 25-30 part, Herba Lythri Salicariae 15-20 part, Flos Lonicerae 10-15 part, Radix Vignae yunnanensis 7-12 part, Radix seu Fructus Actinidiae Purpureae 8-12 part, Myrrha 7-13 part, Indigo Naturalis 4-8 part, Gypsum Fibrosum 3-5 part, Cortex Phellodendri 3-7 part, Fructus Gardeniae 8-12 part, Radix Asparagi door 12-16 part, Radix Ophiopogonis door 12-16 part, Radix Scrophulariae 12-17 part, artificial Calculus Bovis 3-5 part, Borax 1-3 part, Moschus 0.3-0.5 part.

Preferably, 27 parts of Cortex Ampelopsis Humulifoliae Radiciss, 17 parts of Herba Lythri Salicariae, 12 parts of Flos Loniceraes, 10 parts of Radix Vignae yunnanensis, 10 parts of Radix seu Fructus Actinidiae Purpureaes, 10 parts of Myrrhas, 6 parts of Indigo Naturaliss, 4 parts, Gypsum Fibrosum, 5 parts of Cortex Phellodendris, 10 parts of Fructus Gardeniaes, 15 parts, Radix Asparagi door, Radix Ophiopogonis 15 parts, door, 15 parts of Radix Scrophulariaes, 4 parts of artificial Calculus Boviss, 2 parts of Boraxs, 0.4 part, Moschus.

By traditional Chinese medicinal powder preparation method, above-mentioned raw material of Chinese medicine is clayed into power, cross 200 mesh sieves, can make Chinese powder medicine, capsule, pill etc.

Effect of each crude drug:

Cortex Ampelopsis Humulifoliae Radicis promoting blood circulation to remove blood stasis, eliminating inflammation and expelling toxin, granulation promoting long bone, except wind damp eliminating; Herba Lythri Salicariae heat clearing away poison, removing heat from blood, convergence, controls ulcer; Flos Lonicerae heat-clearing and toxic substances removing, anti-inflammation; Indigo Naturalis clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body; Gypsum Fibrosum expelling pathogenic factors from muscles for clearing heat, pathogenic fire purging relieving restlessness; Cortex Phellodendri, Fructus Gardeniae heat clearing and damp drying, eliminating fire and detoxication; Radix Asparagi door lung heat clearing pathogenic fire reducing is nourshing Yin and drynsessmoistening prescription; Radix Ophiopogonis door nourishing YIN and moistening the lung, the relieving restlessness that clears away heart-fire, reinforcing stomach reg fluid; Radix Vignae yunnanensis reducing swelling and alleviating pain, sore-throat relieving; Radix seu Fructus Actinidiae Purpureae clearing away heat-damp and promoting diuresis, tonify deficiency benefit is damaged; The Myrrha blood blood stasis removing that falls apart, subduing swelling and relieving pain; Radix Scrophulariae clearing away heat and cooling blood, pathogenic fire purging YIN nourishing; Artificial Calculus Bovis's removing heat from the heart to restore the consciousness, endogenous wind stopping removing toxic substances; The Moschus refreshment of having one's ideas straightened out, promoting blood circulation to restore menstrual flow; Borax detumescence is anticorrosion, removing heat from the lung and dissipating phlegm.

Clinical data

1, physical data is selected in April, 2010～2011 year medical oral ulcer patient's 140 examples in the court in January, all meets " oral medicine " diagnostic criteria.It is divided into treatment group and matched group at random, treatment group 72 examples, male 40 examples, female's 32 examples, 1.5～50 years old age; Matched group 68 examples, male 39 examples, female's 29 examples, 2～49 years old age.Patient's course of disease is different in size, the shortest 3 days, the longest 5 years.Two groups of patient's physical data are compared, and difference not statistically significant (P>0.05), has comparability.

The oral Chinese powder medicine of the present invention of Therapeutic Method treatment group, each 10g, warm water is taken after mixing it with water, every day 3 times; Matched group oral vitamin B220mg, 2 of buccal cydiodines, every day 3 times, two groups of equal 7d are 1 course for the treatment of.

Criterion of therapeutical effect is effective: ulcer healing or obviously dwindle, and pain obviously alleviates or disappears, and stimulates to external world sensitivity to reduce; Effective: ulcer is dwindled, pain relief; Invalid: before and after treatment, non-evident sympton improves.

Curative effect is evaluated in therapeutic outcome treatment after two courses for the treatment of: treatment group 72 examples, wherein effective 45 examples (62.5%), 26 examples that take a turn for the better (36.1%), invalid 1 example (1.4%), total effective rate 98.6%.Matched group 68 examples, wherein effective 27 examples (39.7%), 26 examples that take a turn for the better (38.2%), invalid 15 examples (22.1%), total effective rate 77.9%.Two groups of obvious effective rates and total effective rate are learned processing (P<0.01) by statistics, and difference has significant.

Find by clinical trial, the curative effect for the treatment of group is not only better than matched group, and curative effect is fast, and relapse rate is low.Treat after 5 days effective 21 examples for the treatment of group, effective 9 examples of matched group; Treat after 10 days effective 42 examples for the treatment of group, effective 16 examples of matched group.Treatment follow-up investigation later six months is found, none recurrence for the treatment of group, and matched group recurs 15 examples.

Model case

Case one: patient Ma Limei, female, 45 years old.Xu Jiahu town, Yishui County in Shandong Province Yuan Li people from village, suffers from oral ulcer more than 4 years, and outbreak repeatedly, can not take food when serious, once takes a lot of medicines all invalid, after examining, takes Chinese powder medicine of the present invention 10 days, oral ulcer recovery from illness, and 1 year without recurrence.

Case two: patient Zhang Zhi China, man, 32 years old, Yishui County in Shandong Province Yao family shop town Bei She people from village, suffer from oral ulcer 6 years, through the whole bag of tricks treatment, oral ulcer is outbreak repeatedly still, take 2 courses for the treatment of of Chinese powder medicine of the present invention, oral ulcer recovery from illness, follows up a case by regular visits to after 1 year without recurrence.

Detailed description of the invention

Embodiment mono-: take Cortex Ampelopsis Humulifoliae Radicis 27g, Herba Lythri Salicariae 17g, Flos Lonicerae 12g, Radix Vignae yunnanensis 10g, Radix seu Fructus Actinidiae Purpureae 10g, Myrrha 10g, Indigo Naturalis 6g, Gypsum Fibrosum 4g, Cortex Phellodendri 5g, Fructus Gardeniae 10g, Radix Asparagi door 15g, Radix Ophiopogonis door 15g, Radix Scrophulariae 15g, artificial Calculus Bovis 4g, Borax 2g, Moschus 0.4g; above-mentioned raw material of Chinese medicine is clayed into power; cross 200 mesh sieves; pack in bag; every bag of 10g; patient's warm water is taken after mixing it with water, and each 1 bag, every day 3 times.

Embodiment bis-: take Cortex Ampelopsis Humulifoliae Radicis 25g, Herba Lythri Salicariae 20g, Flos Lonicerae 10g, Radix Vignae yunnanensis 12g, Radix seu Fructus Actinidiae Purpureae 8g, Myrrha 13g, Indigo Naturalis 4g, Gypsum Fibrosum 5g, Cortex Phellodendri 7g, Fructus Gardeniae 12g, Radix Asparagi door 12g, Radix Ophiopogonis door 16g, Radix Scrophulariae 12g, artificial Calculus Bovis 3g, Borax 3g, Moschus 0.3g; above-mentioned raw material of Chinese medicine is clayed into power; cross 200 mesh sieves; pack in bag; every bag of 10g; patient's warm water is taken after mixing it with water, and each 1 bag, every day 3 times.

Embodiment tri-: take Cortex Ampelopsis Humulifoliae Radicis 30g, Herba Lythri Salicariae 15g, Flos Lonicerae 15g, Radix Vignae yunnanensis 7g, Radix seu Fructus Actinidiae Purpureae 12g, Myrrha 7g, Indigo Naturalis 8g, Gypsum Fibrosum 3g, Cortex Phellodendri 3g, Fructus Gardeniae 8g, Radix Asparagi door 16g, Radix Ophiopogonis door 12g, Radix Scrophulariae 17g, artificial Calculus Bovis 5g, Borax 1g, Moschus 0.5g; above-mentioned raw material of Chinese medicine is clayed into power; cross 200 mesh sieves; pack in bag; every bag of 10g; patient's warm water is taken after mixing it with water, and each 1 bag, every day 3 times.

Claims (1)

1. treat a Chinese medicine composition for oral ulcer, it is characterized in that this Chinese medicine composition is made up of the Chinese medicine of following weight portion: Cortex Ampelopsis Humulifoliae Radicis 25-30 part, Herba Lythri Salicariae 15-20 part, Flos Lonicerae 10-15 part, Radix Vignae yunnanensis 7-12 part, Radix seu Fructus Actinidiae Purpureae 8-12 part, Myrrha 7-13 part, Indigo Naturalis 4-8 part, Gypsum Fibrosum 3-5 part, Cortex Phellodendri 3-7 part, Fructus Gardeniae 8-12 part, Radix Asparagi door 12-16 part, Radix Ophiopogonis door 12-16 part, Radix Scrophulariae 12-17 part, artificial Calculus Bovis 3-5 part, Borax 1-3 part, Moschus 0.3-0.5 part.