CN103083551B

CN103083551B - Traditional Chinese medicine composition for treating infantile suppurative tonsillitis

Info

Publication number: CN103083551B
Application number: CN201310048057.4A
Authority: CN
Inventors: 尹桂华
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-01-24
Filing date: 2013-01-24
Publication date: 2014-01-29
Anticipated expiration: 2033-01-24
Also published as: CN103083551A

Abstract

The invention discloses a traditional Chinese medicine composition for treating infantile suppurative tonsillitis. The disease belongs to the domains of wind heat, acute tonsillitis and the like in traditional Chinese medicine, and is caused by exogenous wind heat pathogenic toxin, obstruction of upper heater, and attack at the throat. Therefore, the traditional Chinese medicines with the effects of clearing heat and removing toxicity, and reducing swelling and removing pus, for example, common calanthe herb, globeflower, aster ageratoides, java speedwell, obcordate raspberry root, kopsia, kerr treebine root and stem, radices trichosanthis, caudate sweetleaf leaf, mint, golden cypress, folium mori, Yunnan cowpea root and liquorice are selected to prepare into decoction. The total effective rate can be up to 95% by a clinical test; pars lymph gland extinction time, antiadoncus extinction time, average hospitalization days and average defervescence time are superior to those of a control group; and clinical popularization and application are deserved.

Description

A kind of Chinese medicine composition for the treatment of children's's suppurative tonsillitis

Technical field

The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine composition of the children's's for the treatment of suppurative tonsillitis.

Background technology

Acute suppurative tonsillitis is as one of comparatively common infectious disease of department of pediatrics, and therefore the feature such as have that morbidity is anxious, the state of an illness is heavy and complication is many has produced very big interference to infant growth promoter etc.Large quantity research is observed and is shown that acute suppurative tonsillitis infection pathogen mostly is Hemolytic streptococcus, so heating, pharyngalgia, antiadoncus etc. usually appear in this type of infant clinically.And take anti-inflammation as main for the treatment of this disease, especially better with penicillin effect, yet along with social development and abuse of antibiotics, clinical observation finds how this type of infant has produced drug resistance, so simple treatment is often difficult to reach ideal effect and this disease very easily recurs, applicant proves through clinical observation for many years, utilizes Children Treated with Chinese Traditional Drugs suppurative tonsillitis to have stable curative effect, the advantage that side effect is little.

Summary of the invention

The Chinese medicine composition that the object of this invention is to provide a kind of children's's for the treatment of suppurative tonsillitis.Primary disease belongs to the categories such as Chinese medicine wind heat, tonsillitis, because of the evil poison of affection due to external wind and heat, stops up in the part of the body cavity above the diaphragm housing the heart and lungs, attacks and rushes due to throat.

The object of the invention is to be achieved through the following technical solutions, the Chinese medicine composition of this treatment children's suppurative tonsillitis is made by the Chinese medicine of following weight portion: Herba seu Radix Calanthes 3-7 part, Flos Trollii 4-8 part, Herba Asteris Ageratoidis 5-9 part, Herba Veronicae javanicae 4-7 part, Radix Rubi obcordati 6-9 part, Fructus Seu Folium Kopsiae Officinalis 5-10 part, Radix Cissi Kerrii 2-5 part, Radix Trichosanthis 9-15 part, Folium Symplocoris Caudatae 1-5 part, Herba Menthae 7-10 part, Cortex Phellodendri 8-15 part, Folium Mori 5-15 part, Radix Vignae yunnanensis 10-20 part, Radix Glycyrrhizae 3-6 part.

Preferably, 5 parts of Herba seu Radix Calanthess, 6 parts of Flos Trolliis, 7 parts of Herba Asteris Ageratoidis, 5 parts of Herba Veronicae javanicaes, 7 parts of Radix Rubi obcordatis, 7 parts of Fructus Seu Folium Kopsiae Officinalis, 4 parts of Radix Cissi Kerrii, 12 parts of Radix Trichosanthis, Folium Symplocoris Caudatae 3,8 parts of Herba Menthaes, 12 parts of Cortex Phellodendris, 10 parts, Folium Mori, 15 parts of Radix Vignae yunnanensis, 4 parts, Radix Glycyrrhizae.

Preparation method is made decoction by above-mentioned Chinese medicine according to traditional preparation method.

In side: Herba seu Radix Calanthes, Flos Trollii, Radix Vignae yunnanensis heat-clearing and toxic substances removing; Herba Asteris Ageratoidis, Herba Veronicae javanicae, Radix Rubi obcordati, Radix Cissi Kerrii removing toxic substances and promoting subsidence of swelling, dispelling wind to relieve the exterior syndrome, cooling blood for hemostasis; Fructus Seu Folium Kopsiae Officinalis anti-inflammatory analgetic, channels sootheing and network vessel quickening; Radix Trichosanthis, Folium Symplocoris Caudatae clearing away heat and promoting production of body fluid, detumescence and apocenosis; Herba Menthae dispelling wind and heat pathogens, the clear sharp head, rash sore-throat relieving; Cortex Phellodendri heat clearing and damp drying, eliminating fire and detoxication, brings down a fever except steaming; Folium Mori dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness; Radix Glycyrrhizae relieving spasm to stop pain, invigorating the spleen and replenishing QI, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.

Clinical data

1, the selected case of physical data is my institute's department of pediatrics Hospitalized Children, diagnosis all meets < < diagnostics basis > > relevant criterion, totally 120 examples, man's 56 examples, female's 64 examples, age 3-10 year, 7 years old mean age, 38 ℃ of-39.0 ℃ of 88 examples of body temperature, 39.1 ℃ of-40.0 ℃ of 24 examples, 40.0 ℃ of 8 above examples, the enlargement of the equal I-III degree of tonsil, congested, there is yellow purulent secretion on surface, there are yellow point-like exudate 48 examples in right side wherein, there are white membranaceous secretions 52 examples in left side, bilateral has secretions 20 examples, tell pharyngalgia, dysphagia 86 examples, all there is heating, fear of cold, without shiver with cold, without expectorant, all infants all have lower jaw lymphadenectasis, Semen Viciae fabae or Semen Glycines size, tenderness is obvious, movable good, blood routine examination: numeration of leukocyte (0.86-1.42) * 10 ²/ L, neutrophilic granulocyte 0.68-0.76, there is shift to left phenomenon, red tongue with yellow fur, floating and rapid pulse, is divided into each 60 examples for the treatment of group and matched group at random, and two groups of infants are in aspect comparisons such as age, sex, tonsil situations, difference not statistically significant (P > 0.05), has comparability.

2, Therapeutic Method treatment group infant is taken Chinese medicine composition of the present invention, get Herba seu Radix Calanthes 5g, Flos Trollii 6g, Herba Asteris Ageratoidis 7g, Herba Veronicae javanicae 5g, Radix Rubi obcordati 7g, Fructus Seu Folium Kopsiae Officinalis 7g, Radix Cissi Kerrii 4g, Radix Trichosanthis 12g, Folium Symplocoris Caudatae 3g, Herba Menthae 8g, Cortex Phellodendri 12g, Folium Mori 10g, Radix Vignae yunnanensis 15g, Radix Glycyrrhizae 4g, decocting becomes decoction, 1 dose of every day, early, evening 2 sub-services; Matched group routine gives cefotaxime 100-200mg/kg/d and adds 5% glucose injection 100-250ml, intravenous drip, once a day; Two groups equal 5 days be a course for the treatment of, treat and add up curative effect two courses for the treatment of.

3, the < < traditional Chinese medical science disease Standardization of diagnosis and curative effect > > that criterion of therapeutical effect is promulgated with reference to Department of Medical Administration of State Administration of Traditional Chinese Medicine in June, 1994 carries out.Cure: body temperature is normal, and hemogram is normal, pharyngeal transference cure, tonsil is not congested, no pus point.Take a turn for the better: still have low grade fever, hemogram approaches normal, and pharyngeal symptom alleviates, and tonsil pus point is eliminated.Do not heal: sings and symptoms is not improved.

4, all cases of therapeutic outcome (1) are all cured and are left hospital, two groups of volume submental lymph nodes extinction times, and antiadoncus extinction time, average hospital days and average fever time comparison, in Table 1.Treatment group volume submental lymph nodes extinction time, antiadoncus extinction time, average hospital days are compared with matched group, difference is very significant (P < 0.01), treatment group is obviously better than matched group, the equal fever time for the treatment of group and matched group comparison, no significant difference (P > 0.05).

Curative effect comparison after two courses for the treatment of of table 1 liang group treatment

With matched group comparison, * P < 0.01, Δ P > 0.05

(2) two groups treatment two courses for the treatment of after curative effect comparison, in Table 2.

Table 2 liang group treatment curative effect comparative example (%) after two weeks

With matched group comparison, P < 0.05.

As can be seen from Table 1, treatment group cure rate is 75.00%, and matched group is 38.33%, has significant difference (P < 0.01); Treatment group total effective rate is 95.00%, and matched group is 80.00% also to have comparability (P < 0.05).

The specific embodiment

Embodiment mono-: take Herba seu Radix Calanthes 5g, Flos Trollii 6g, Herba Asteris Ageratoidis 7g, Herba Veronicae javanicae 5g, Radix Rubi obcordati 7g, Fructus Seu Folium Kopsiae Officinalis 7g, Radix Cissi Kerrii 4g, Radix Trichosanthis 12g, Folium Symplocoris Caudatae 3g, Herba Menthae 8g, Cortex Phellodendri 12g, Folium Mori 10g, Radix Vignae yunnanensis 15g, Radix Glycyrrhizae 4g.Medicine-feeding is made to decoction according to traditional preparation method

Embodiment bis-: take Herba seu Radix Calanthes 3g, Flos Trollii 8g, Herba Asteris Ageratoidis 9g, Herba Veronicae javanicae 4g, Radix Rubi obcordati 6g, Fructus Seu Folium Kopsiae Officinalis 10g, Radix Cissi Kerrii 2g, Radix Trichosanthis 9g, Folium Symplocoris Caudatae 5g, Herba Menthae 7g, Cortex Phellodendri 8g, Folium Mori 15g, Radix Vignae yunnanensis 10g, Radix Glycyrrhizae 6g.Medicine-feeding is made to decoction according to traditional preparation method

Embodiment tri-: take Herba seu Radix Calanthes 7g, Flos Trollii 4g, Herba Asteris Ageratoidis 5g, Herba Veronicae javanicae 7g, Radix Rubi obcordati 9g, Fructus Seu Folium Kopsiae Officinalis 5g, Radix Cissi Kerrii 5g, Radix Trichosanthis 15g, Folium Symplocoris Caudatae 1g, Herba Menthae 10g, Cortex Phellodendri 15g, Folium Mori 5g, Radix Vignae yunnanensis 20g, Radix Glycyrrhizae 3g.Medicine-feeding is made to decoction according to traditional preparation method.

Claims

1. treat a Chinese medicine composition for children's's suppurative tonsillitis, it is characterized in that this Chinese medicine composition made by the Chinese medicine of following weight portion: Herba seu Radix Calanthes 3-7 part, Flos Trollii 4-8 part, Herba Asteris Ageratoidis 5-9 part, Herba Veronicae javanicae 4-7 part, Radix Rubi obcordati 6-9 part, Fructus Seu Folium Kopsiae Officinalis 5-10 part, Radix Cissi Kerrii 2-5 part, Radix Trichosanthis 9-15 part, Folium Symplocoris Caudatae 1-5 part, Herba Menthae 7-10 part, Cortex Phellodendri 8-15 part, Folium Mori 5-15 part, Radix Vignae yunnanensis 10-20 part, Radix Glycyrrhizae 3-6 part.

2. a kind of Chinese medicine composition for the treatment of children's's suppurative tonsillitis according to claim 1, is characterized in that this Chinese medicine composition made by the Chinese medicine of following weight portion: 5 parts of Herba seu Radix Calanthess, 6 parts of Flos Trolliis, 7 parts of Herba Asteris Ageratoidis, 5 parts of Herba Veronicae javanicaes, 7 parts of Radix Rubi obcordatis, 7 parts of Fructus Seu Folium Kopsiae Officinalis, 4 parts of Radix Cissi Kerrii, 12 parts of Radix Trichosanthis, Folium Symplocoris Caudatae 3,8 parts of Herba Menthaes, 12 parts of Cortex Phellodendris, 10 parts, Folium Mori, 15 parts of Radix Vignae yunnanensis, 4 parts, Radix Glycyrrhizae.