CN101869110B - Composite for restating viruses of plants and application thereof - Google Patents
Composite for restating viruses of plants and application thereof Download PDFInfo
- Publication number
- CN101869110B CN101869110B CN 201010226509 CN201010226509A CN101869110B CN 101869110 B CN101869110 B CN 101869110B CN 201010226509 CN201010226509 CN 201010226509 CN 201010226509 A CN201010226509 A CN 201010226509A CN 101869110 B CN101869110 B CN 101869110B
- Authority
- CN
- China
- Prior art keywords
- ribavirin
- fucoidin
- composition
- virus
- sodium sulfate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 241000700605 Viruses Species 0.000 title claims abstract description 40
- 239000002131 composite material Substances 0.000 title abstract 6
- IWUCXVSUMQZMFG-AFCXAGJDSA-N Ribavirin Chemical compound N1=C(C(=O)N)N=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 IWUCXVSUMQZMFG-AFCXAGJDSA-N 0.000 claims abstract description 49
- 229960000329 ribavirin Drugs 0.000 claims abstract description 48
- HZCAHMRRMINHDJ-DBRKOABJSA-N ribavirin Natural products O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1N=CN=C1 HZCAHMRRMINHDJ-DBRKOABJSA-N 0.000 claims abstract description 48
- 201000010099 disease Diseases 0.000 claims abstract description 17
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 17
- 239000000843 powder Substances 0.000 claims abstract description 11
- 235000007688 Lycopersicon esculentum Nutrition 0.000 claims abstract description 8
- 240000003768 Solanum lycopersicum Species 0.000 claims abstract description 8
- 241000208125 Nicotiana Species 0.000 claims abstract description 7
- 235000002637 Nicotiana tabacum Nutrition 0.000 claims abstract description 7
- 239000007921 spray Substances 0.000 claims abstract description 5
- 239000000203 mixture Substances 0.000 claims description 39
- RCEAADKTGXTDOA-UHFFFAOYSA-N OS(O)(=O)=O.CCCCCCCCCCCC[Na] Chemical compound OS(O)(=O)=O.CCCCCCCCCCCC[Na] RCEAADKTGXTDOA-UHFFFAOYSA-N 0.000 claims description 22
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
- 239000005995 Aluminium silicate Substances 0.000 claims description 10
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 10
- 235000012211 aluminium silicate Nutrition 0.000 claims description 10
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 claims description 10
- 230000002507 anti-phytoviral effect Effects 0.000 claims description 6
- 238000009736 wetting Methods 0.000 claims description 5
- 239000004480 active ingredient Substances 0.000 claims description 2
- 241000196324 Embryophyta Species 0.000 abstract description 9
- 238000000034 method Methods 0.000 abstract description 7
- 230000000694 effects Effects 0.000 abstract description 6
- 238000002156 mixing Methods 0.000 abstract description 5
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 230000000361 pesticidal effect Effects 0.000 abstract 1
- 239000004563 wettable powder Substances 0.000 abstract 1
- 241000723873 Tobacco mosaic virus Species 0.000 description 9
- 241000724252 Cucumber mosaic virus Species 0.000 description 7
- 230000003612 virological effect Effects 0.000 description 7
- 239000002904 solvent Substances 0.000 description 6
- GQPLMRYTRLFLPF-UHFFFAOYSA-N Nitrous Oxide Chemical compound [O-][N+]#N GQPLMRYTRLFLPF-UHFFFAOYSA-N 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 5
- 230000000052 comparative effect Effects 0.000 description 4
- 241000709992 Potato virus X Species 0.000 description 2
- 230000000840 anti-viral effect Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 238000005457 optimization Methods 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- -1 polysaccharide sulfate Chemical class 0.000 description 2
- AUHDWARTFSKSAC-HEIFUQTGSA-N (2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-(6-oxo-1H-purin-9-yl)oxolane-2-carboxylic acid Chemical compound [C@]1([C@H](O)[C@H](O)[C@@H](CO)O1)(N1C=NC=2C(O)=NC=NC12)C(=O)O AUHDWARTFSKSAC-HEIFUQTGSA-N 0.000 description 1
- DBTMGCOVALSLOR-DEVYUCJPSA-N (2s,3r,4s,5r,6r)-4-[(2s,3r,4s,5r,6r)-3,5-dihydroxy-6-(hydroxymethyl)-4-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)oxane-2,3,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](CO)O[C@H](O)[C@@H]2O)O)O[C@H](CO)[C@H]1O DBTMGCOVALSLOR-DEVYUCJPSA-N 0.000 description 1
- 241000195493 Cryptophyta Species 0.000 description 1
- 101710088194 Dehydrogenase Proteins 0.000 description 1
- 208000007514 Herpes zoster Diseases 0.000 description 1
- 208000000440 Herpetic Stomatitis Diseases 0.000 description 1
- GRSZFWQUAKGDAV-UHFFFAOYSA-N Inosinic acid Natural products OC1C(O)C(COP(O)(O)=O)OC1N1C(NC=NC2=O)=C2N=C1 GRSZFWQUAKGDAV-UHFFFAOYSA-N 0.000 description 1
- 102000014150 Interferons Human genes 0.000 description 1
- 108010050904 Interferons Proteins 0.000 description 1
- 229920001543 Laminarin Polymers 0.000 description 1
- 239000005717 Laminarin Substances 0.000 description 1
- 201000005505 Measles Diseases 0.000 description 1
- 206010067152 Oral herpes Diseases 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 208000002606 Paramyxoviridae Infections Diseases 0.000 description 1
- 206010034038 Parotitis Diseases 0.000 description 1
- 206010035664 Pneumonia Diseases 0.000 description 1
- 241000015177 Saccharina japonica Species 0.000 description 1
- 210000001744 T-lymphocyte Anatomy 0.000 description 1
- 208000036142 Viral infection Diseases 0.000 description 1
- ABUGVBRDFWGJRD-CHOYNLESSA-N [9-[(2r,3r,4s,5r)-3,4-dihydroxy-5-methyloxolan-2-yl]-2-(2,4-dinitrophenyl)sulfanylpurin-6-yl] [hydroxy(phosphonooxy)phosphoryl] hydrogen phosphate Chemical compound O[C@@H]1[C@H](O)[C@@H](C)O[C@H]1N1C2=NC(SC=3C(=CC(=CC=3)[N+]([O-])=O)[N+]([O-])=O)=NC(OP(O)(=O)OP(O)(=O)OP(O)(O)=O)=C2N=C1 ABUGVBRDFWGJRD-CHOYNLESSA-N 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 239000003443 antiviral agent Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 241001493065 dsRNA viruses Species 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 206010016165 failure to thrive Diseases 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- RQFCJASXJCIDSX-UUOKFMHZSA-N guanosine 5'-monophosphate Chemical compound C1=2NC(N)=NC(=O)C=2N=CN1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O RQFCJASXJCIDSX-UUOKFMHZSA-N 0.000 description 1
- 235000013928 guanylic acid Nutrition 0.000 description 1
- 239000004226 guanylic acid Substances 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 231100000283 hepatitis Toxicity 0.000 description 1
- 230000007236 host immunity Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 239000002955 immunomodulating agent Substances 0.000 description 1
- 229940121354 immunomodulator Drugs 0.000 description 1
- 230000002584 immunomodulator Effects 0.000 description 1
- 206010022000 influenza Diseases 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 235000013902 inosinic acid Nutrition 0.000 description 1
- 239000004245 inosinic acid Substances 0.000 description 1
- 229940028843 inosinic acid Drugs 0.000 description 1
- 229940079322 interferon Drugs 0.000 description 1
- 206010023332 keratitis Diseases 0.000 description 1
- 210000002540 macrophage Anatomy 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 230000008635 plant growth Effects 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 241000701161 unidentified adenovirus Species 0.000 description 1
- 229940100050 virazole Drugs 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a composite for resisting viruses of plants. In the composite, fucoidin and ribavirin are used as effective constituents, wherein the content of fucoidin is 0.5-5wt%, and the content of ribavirin is 0.5-5wt%. The invention also discloses the application of the composite in preventing tomato virus diseases and tobacco virus diseases. In the composite, through the blending of the fucoidin and ribavirin, the pesticide effect is remarkably improved, and the control efficiency of the compound is good. In addition, the composite can be aqueous solution agent, soluble powder and wettable powder, and is convenient to spray and use. By adopting the method of the invention, the effect of preventing the viruses of plants is more remarkable.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition and application thereof of anti-plant viral disease, particularly a kind of fucoidin is mixed for the composition of Antiphytoviral and the application of said composition mutually with ribavirin.
Background technology
Fucoidin is the polysaccharide that extracts from large edible algae sea-tangle (Laminaria japonica), main component is fucosan (Focoidan), be the polymer of d-L-fucose-4-sulfuric ester, claim again algal polysaccharide sulfate, laminarin.Fucoidin is a kind of host's macrophage, T cell to be had direct acting immunomodulator, it have antiviral, regulate the host immunity function and stimulate the functions such as interferon formation.
(Ribavirin has another name called virazole to ribavirin, Ribavirin, ribavirin, the happy star of prestige, Ribavirin, Ribavirin, Ribavirin), be broad-spectrum antiviral drug, can suppress inosinicacid-5-phosphate dehydrogenase, the blocking-up inosinicacid is converted into guanylic acid, thereby the RNA and the DNA that suppress virus are synthetic, all have inhibition to copy effect to dna virus and RNA virus.Be used for preventing and treating influenza, parainfluenza, Type A. B. C hepatitis, measles, parotitis, varicella, herpe simplex, herpes zoster, viral eye keratitis, herpetic stomatitis, children's's adenovirus pneumonia, may also have antitumor action.Also can be used for Control of Plant Virus Disease.
The cosmopolitian plant viral species has reached 909 kinds at present, and China has reported kind more than 100.Most economic crops all because of the harm that is subject to virus disease so that plant part or whole growth failures seriously hinder plant growth, affect quality and reduction output, it is withered, mottled and rotten that common sympton has.The plant virus kind is many, endangers wide control difficulty.
The inventor has developed the fucoidin aqua product, and is used for preventing and treating the viroses of plant, but single use fucoidin dosage when low drug effect also lower, cost was too high when using dosage was excessive.Single use ribavirin is also lower because of control efficiency.
Summary of the invention
The present invention is in order to overcome above-mentioned deficiency, provide a kind of fucoidin and ribavirin to be mixed for the composition of anti-plant viral disease, the said composition cost is low, and the Antiphytoviral effect is remarkable, has improved the effect of fucoidin and ribavirin anti-plant viral disease.
The present invention also provides the application in control tomato virus disease or tobacco virus of this anti-plant virus composition.
The present invention is achieved by the following measures:
Innovative point of the present invention is fucoidin and ribavirin be mixed and makes the composition pesticide of anti-plant viral disease, via plant immunity can be induced and strengthen to said composition, thereby suppress infecting of virus, reach effect antiviral and volume increase, more remarkable than these two kinds of ingredients for preventing and treating effects of independent usefulness.The inventor has drawn the technical scheme that following fucoidin and ribavirin are mixed through great many of experiments and application:
A kind of anti-plant virus composition is characterized in that: take fucoidin and ribavirin as active ingredient, wherein, the content of fucoidin is 0.5-5wt%, and the content of ribavirin is 0.5-5wt%.
Above-mentioned anti-plant virus composition can be aqua, comprises the component of following percetage by weight:
Fucoidin 0.5-5%
Ribavirin 0.5-5%
Lauryl sodium sulfate 3%
Water surplus.
Above-mentioned anti-plant virus composition also can be soluble powder or wetting powder, comprises the component of following percetage by weight:
Fucoidin 0.5-5%
Ribavirin 0.5-5%
Lauryl sodium sulfate 3%
White carbon 5-6%
NNO 5-10％
The kaolin surplus.
When above-mentioned anti-plant virus composition was aqua, its optimization formula was (percetage by weight):
Fucoidin 2-3%
Ribavirin 2-3%
Lauryl sodium sulfate 3%
Water surplus.
When above-mentioned anti-plant virus composition was soluble powder or wetting powder, its optimization formula was (percetage by weight):
Fucoidin 2-3%
Ribavirin 2-3%
Lauryl sodium sulfate 3%
White carbon 6%
NNO 8％
The kaolin surplus.
In the above-mentioned anti-plant virus composition, the mass ratio of fucoidin and ribavirin is 1: 5～5: 1.
In the above-mentioned Antiphytoviral composition, the mass ratio of fucoidin and ribavirin is preferably 1: 1.
The application of above-mentioned Antiphytoviral composition in control tomato virus disease or tobacco virus is characterized in that: with said composition dilute with water 500-1000 doubly, be sprayed on the crop at the virus disease initial stage of origination.
In the above-mentioned application, it is characterized in that said composition between crop sprays twice, twice interval 7-10 days.
The preparation method of this composition:
Aqua: first water dissolving ribavirin, add the female medicine mixing of fucoidin, adding lauryl sodium sulfate dissolving and mixing namely becomes aqua again.
Soluble powder or wetting powder: fucoidin, ribavirin, lauryl sodium sulfate, white carbon, NNO and kaolin are mixed by proportioning.Wherein, as diffusant, kaolin is as auxiliary material as wetting agent, NNO for white carbon, and fucoidin, ribavirin and lauryl sodium sulfate are effective ingredient.After each component mixes, they are crushed to the 300-400 order, namely get the present composition.
Beneficial effect:
1, composition of the present invention has significantly improved drug effect by being mixed of fucoidin and ribavirin, and control efficiency is good, and the present invention is aqua, soluble powder, wetting powder, is convenient to spray, and is easy to use.
2, adopt method prevention and treatment effect on plant viral diseases of the present invention more remarkable.
Embodiment
The present invention will be described in detail below by specific embodiment, and following explanation only is exemplary, does not limit the invention.If no special instructions, following percentage is percetage by weight.
Example 1
Component and content: fucoidin 1%, ribavirin 1%, lauryl sodium sulfate 3%, water 95% (solvent).
Method for making: first water dissolving ribavirin, then add the female medicine mixing of fucoidin, adding lauryl sodium sulfate dissolving and mixing namely becomes aqua again.
Example 2
Component and content: fucoidin 2%, ribavirin 3%, lauryl sodium sulfate 3%, water 92% (solvent).
The preparation method is with embodiment 1.
Example 3
Component and content: fucoidin 0.5%, ribavirin 2.5%, lauryl sodium sulfate 3%, water 94% (solvent).
The preparation method is with embodiment 1.
Example 4
Component and content: fucoidin 5%, ribavirin 1%, lauryl sodium sulfate 3%, water 91% (solvent).
The preparation method is with embodiment 1.
Example 5
Component and content: fucoidin 1%, ribavirin 5%, lauryl sodium sulfate 3%, white carbon 6%, NNO5%, kaolin surplus.
Method for making: fucoidin, ribavirin, lauryl sodium sulfate, white carbon, NNO and kaolin are mixed by proportioning, be crushed to the 300-400 order, namely get the present composition.
Example 6
Component and content: fucoidin 2%, ribavirin 0.5%, lauryl sodium sulfate 3%, white carbon 5%, NNO10%, kaolin surplus.
Method for making is with embodiment 5.
Example 7
Component and content: fucoidin 3%, ribavirin 2%, lauryl sodium sulfate 3%, white carbon 6%, NNO8%, kaolin surplus.
The preparation method is with embodiment 5.
Comparative Examples 1
Compare with embodiment 1, component is: fucoidin 2%, lauryl sodium sulfate 3%, water 95% (solvent).
Comparative Examples 2
Compare with embodiment 1, component is: ribavirin 2%, lauryl sodium sulfate 3%, water 95% (solvent).
The using method of the composition that above-described embodiment and Comparative Examples make is as follows: with 500 times and 1000 times of the above-mentioned composition difference dilute with waters that makes, spray at tomato virus disease or tobacco virus their early stage, sprayed once after 7-10 days again.
The virus of harm tobacco is mainly tobacco mosaic virus (TMV), also is Tomato mosaic virus (TOMV).The virus of harm tomato mainly contains Tomato mosaic virus (TOMV), cucumber mosaic virus (CMV), potato virus X (PVY), and the below describes take tobacco mosaic virus (TMV) and cucumber mosaic virus (CMV) as the control efficiency of example to the present composition.
Table 1 pair tobacco virus (TMV) control efficiency
Table 2 pair tomato virus disease (CMV) control efficiency
* the data heel with different letters, the expression variance analysis is at F
0.05Significant difference on the level.(DMRT method).
The present composition is also close with cucumber mosaic virus (CMV) to the control efficiency of potato virus X (PVY).
As can be seen from the above table, the control efficiency that fucoidin and ribavirin are used with is good, can find out with the contrast of Comparative Examples 1 and 2 that from embodiment 1 composition of the present invention is more remarkable to the control efficiency of tomato virus disease than using separately fucoidin or the ribavirin of identical dose.
Claims (9)
1. anti-plant virus composition is characterized in that: take fucoidin and ribavirin as active ingredient, wherein, the content of fucoidin is 0.5-5wt%, and the content of ribavirin is 0.5-5wt%.
2. anti-plant virus composition according to claim 1, it is characterized in that: said composition is aqua, comprises the component of following percetage by weight:
Fucoidin 0.5-5%
Ribavirin 0.5-5%
Lauryl sodium sulfate 3%
Water surplus.
3. anti-plant virus composition according to claim 1, it is characterized in that: said composition is soluble powder or wetting powder, comprises the component of following percetage by weight:
Fucoidin 0.5-5%
Ribavirin 0.5-5%
Lauryl sodium sulfate 3%
White carbon 5-6%
NNO 5-10%
The kaolin surplus.
4. anti-plant virus composition according to claim 2 is characterized in that comprising the component of following percetage by weight:
Fucoidin 2-3%
Ribavirin 2-3%
Lauryl sodium sulfate 3%
Water surplus.
5. anti-plant virus composition according to claim 3 is characterized in that comprising the component of following percetage by weight:
Fucoidin 2-3%
Ribavirin 2-3%
Lauryl sodium sulfate 3%
White carbon 6%
NNO 8%
The kaolin surplus.
6. each described anti-plant virus composition according to claim 1-3 is characterized in that: the mass ratio of fucoidin and ribavirin is 1:5 ~ 5:1.
7. Antiphytoviral composition according to claim 6, it is characterized in that: the mass ratio of fucoidin and ribavirin is 1:1.
8. the application of each described Antiphytoviral composition in control tomato virus disease or tobacco virus among the claim 1-5 is characterized in that: with said composition dilute with water 500-1000 doubly, be sprayed on the crop at the virus disease initial stage of origination.
9. application according to claim 8 is characterized in that: said composition between crop sprays twice, twice interval 7-10 days.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201010226509 CN101869110B (en) | 2010-07-14 | 2010-07-14 | Composite for restating viruses of plants and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201010226509 CN101869110B (en) | 2010-07-14 | 2010-07-14 | Composite for restating viruses of plants and application thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101869110A CN101869110A (en) | 2010-10-27 |
| CN101869110B true CN101869110B (en) | 2013-03-13 |
Family
ID=42994343
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201010226509 Active CN101869110B (en) | 2010-07-14 | 2010-07-14 | Composite for restating viruses of plants and application thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101869110B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103960239B (en) * | 2014-04-24 | 2015-12-30 | 山东圣鹏科技股份有限公司 | A kind of anti-plant virus composition and application thereof |
| CN113767916B (en) * | 2021-11-10 | 2022-03-01 | 山东科大创业生物有限公司 | Composition for resisting plant virus diseases and preparation method and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1327740A (en) * | 2000-06-14 | 2001-12-26 | 西安海浪化工有限公司 | Inhibitor for preventing and eliminating plant viruses |
| CN1344565A (en) * | 2001-10-19 | 2002-04-17 | 汤洁 | Fucoidin ester as antiviral immunoregulator and its prepn |
| WO2009027057A1 (en) * | 2007-08-24 | 2009-03-05 | Marinomed Biotechnologie Gmbh | Antiviral composition comprising a sulfated polysaccharide |
-
2010
- 2010-07-14 CN CN 201010226509 patent/CN101869110B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1327740A (en) * | 2000-06-14 | 2001-12-26 | 西安海浪化工有限公司 | Inhibitor for preventing and eliminating plant viruses |
| CN1344565A (en) * | 2001-10-19 | 2002-04-17 | 汤洁 | Fucoidin ester as antiviral immunoregulator and its prepn |
| WO2009027057A1 (en) * | 2007-08-24 | 2009-03-05 | Marinomed Biotechnologie Gmbh | Antiviral composition comprising a sulfated polysaccharide |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101869110A (en) | 2010-10-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102047883B (en) | Plant virus disease-resistant composition containing lentinan and brassinolide and application thereof | |
| CN102349538B (en) | Anti-plant virus pesticide composition | |
| CN103719088B (en) | A kind of biogenic pesticide composition and application thereof preventing and treating the viroses of plant | |
| CN101869111B (en) | Composition comprising lentinan and ribavirin for resisting plant virus diseases and application thereof | |
| CN103875671A (en) | Bactericidal composition | |
| CN109938027A (en) | A kind of composition pesticide of anti-plant viral disease and its preparation method and application | |
| CN103651382A (en) | Insecticidal composition containing chitosan oligosaccharide and applications | |
| CN101878761B (en) | Anti-plant viral disease combination containing fucoidin and application thereof | |
| CN101869110B (en) | Composite for restating viruses of plants and application thereof | |
| CN104488925A (en) | Pesticide composition containing sterol and flonicamid | |
| CN103960239B (en) | A kind of anti-plant virus composition and application thereof | |
| CN102823594B (en) | Plant virus disease resistance composition comprising diethyl aminoethyl hexanoate and lentinan | |
| CN102217638B (en) | Pesticide composition for preventing and treating plant virus diseases | |
| CN109362734A (en) | Antiphytoviral composition and its application in plant virus resistance | |
| CN104938491A (en) | Pesticide combination for preventing corn top rot | |
| CN109169666A (en) | A kind of composition pesticide containing propionylbrassinolide and amino-oligosaccharide | |
| CN103636668B (en) | Sterilization composition containing Dufulin and orysastrobin | |
| CN107646860A (en) | A kind of anti-plant virus composition containing lentinan | |
| CN103598197A (en) | Plant virus disease control medicament | |
| CN106857582A (en) | A kind of composition pesticide containing tetramycin | |
| CN113100247A (en) | Plant immunity inducing and resisting agent for preventing and controlling areca-nut yellowing disease and using method thereof | |
| CN103636670B (en) | Sterilization composition containing Dufulin and enestroburin | |
| CN104206383B (en) | Anti-plant virus composition and application thereof | |
| CN103960296A (en) | Plant virus disease resisting composition and application thereof | |
| CN104782660A (en) | Drug composition resisting plant viruses, and preparation and application of drug composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CP03 | Change of name, title or address | ||
| CP03 | Change of name, title or address |
Address after: 272063 resident of yutun Town, Rencheng District, Jining City, Shandong Province (yutun Industrial Park) Patentee after: SHANDONG SHENGPENG TECHNOLOGY CO.,LTD. Address before: 272063 resident of yutun Town, Rencheng District, Jining City, Shandong Province Patentee before: SHANDONG SHENGPENG PESTICIDE Co.,Ltd. |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: An anti plant virus disease composition and its application Effective date of registration: 20221114 Granted publication date: 20130313 Pledgee: Jining Rushang Village Bank Co.,Ltd. Liying sub branch Pledgor: SHANDONG SHENGPENG TECHNOLOGY CO.,LTD. Registration number: Y2022980022002 |
|
| PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
| PC01 | Cancellation of the registration of the contract for pledge of patent right |
Granted publication date: 20130313 Pledgee: Jining Rushang Village Bank Co.,Ltd. Liying sub branch Pledgor: SHANDONG SHENGPENG TECHNOLOGY CO.,LTD. Registration number: Y2022980022002 |