CN101862347A - Disinfectant - Google Patents

Abstract

The invention relates to disinfectant comprising the following components by weight percent: 0.1 to 1.0 percent of iodine, 0.4 to 4.0 percent of polyvinylpyrrolidone, 0.03 to 0.3 percent of potassium iodide, 0.02 to 0.2 percent of sodium dodecyl benzene sulfonate and 94.50 to 99.45 percent of purified water. The invention is a disinfectant which has strong sterilization efficacy, high safety, good stability and low corrosiveness and irritability, can be used for the disinfection of the skin, mucous membranes and wounds and has low effective iodine content.

Description

Disinfectant solution

[technical field]

The present invention relates to contain medicinal preparation, iodine and the chemical compound thereof of inorganic effective ingredient, refer to a kind of disinfectant solution especially.

[background technology]

Most popular detoxicating liquid is to contain iodic disinfecting liquid on the China market at present, with iodine tincture is many, as everyone knows, iodine belongs to halogen family, it has dual character, resemble a double-edged sword: it has the total strong oxidation characteristic of halogen on the one hand, and bacterial virus is had the powerful ability of killing, and belongs to the high-effective disinfecting element.It has intensive corrosivity and zest again on the other hand, can only be used for skin degerming, can not be used for mucosa and wound disinfection, if handle badly, will damage human body or animal body.All the time, people have no idea an optimal state is handled in the dual character of iodine, that is: fungicidal effectiveness and safety all reach maximization.And the available iodine content of general iodine tincture is all more than 2%, and this consumption for iodine resource more and more in short supply is very inappropriate.

[summary of the invention]

The object of the present invention is to provide that a kind of fungicidal effectiveness is strong, safe, good stability, and corrosivity and zest is low, can be used for skin, mucosa and wound disinfection and the low disinfectant solution of available iodine content.

The technical solution adopted for the present invention to solve the technical problems is: a kind of disinfectant solution is characterized in that; Component is as follows by weight percentage:

1) iodine 0.1%～1.0%;

2) polyvinylpyrrolidone 0.4%～4.0%;

3) potassium iodide: 0.03%～0.3%;

4) dodecylbenzene sodium sulfonate 0.02%～0.2%;

5) purified water 94.50%～99.45%.

This component activates the iodine molecule that does not possess bactericidal activity substantially and is effective sterilization factors, so both improved fungicidal effectiveness greatly, avoided the waste of I again, be that a kind of fungicidal effectiveness is strong, safe, good stability, and corrosivity and zest is low, can be used for skin, mucosa and wound disinfection and the low disinfectant solution of available iodine content.The shortcoming of can also overcome general iodic disinfecting liquid Huang, gluing, steeping.

[specific embodiment]

Embodiment one:

1) iodine 0.1%:

2) polyvinylpyrrolidone 0.4%;

3) potassium iodide: 0.03%;

4) dodecylbenzene sodium sulfonate 0.02%;

5) purified water 99.45%.

Above-mentioned component is mixed abundant stirring the in back make medicinal liquid, laboratory test acts on 7 parts of clocks, is 99.94 to the escherichia coli killing rate; To the Candida albicans killing rate is 99.99; Killing rate to golden yellow grape grape coccus is 99.95; 1 minute action time, the killing rate of adversary's skin surface natural bacteria is 99.76.Its bactericidal effect is better than 2% iodine tincture, is applied to skin, mucosa and wound, finds no discomfort.

Embodiment two:

1) iodine 0.5%;

2) polyvinylpyrrolidone 2.0%;

3) potassium iodide: 0.15%;

4) dodecylbenzene sodium sulfonate 0.1%;

5) purified water 97.25%.

Above-mentioned component is mixed abundant stirring the in back make medicinal liquid, laboratory test acts on 7 parts of clocks, is 99.93 to the escherichia coli killing rate; To the Candida albicans killing rate is 99.95; Killing rate to golden yellow grape grape coccus is 99.97; 1 minute action time, the killing rate of adversary's skin surface natural bacteria is 99.75.Its bactericidal effect is better than 2% iodine tincture, is applied to skin, mucosa and wound, finds no discomfort.

Preferred embodiment three:

1) iodine 1.0%;

2) polyvinylpyrrolidone 4.0%;

3) potassium iodide: 0.3%;

4) dodecylbenzene sodium sulfonate 0.2%;

5) purified water 94.5%.

Above-mentioned component is mixed abundant stirring the in back make medicinal liquid, laboratory test acts on 7 parts of clocks, is 99.95 to the escherichia coli killing rate; To the Candida albicans killing rate is 99.99; Killing rate to golden yellow grape grape coccus is 99.96; 1 minute action time, the killing rate of adversary's skin surface natural bacteria is 99.77.Its bactericidal effect is better than 2% iodine tincture, is applied to skin, mucosa and wound, finds no discomfort.

Above embodiment carries out the acute oral test, per os LD to female male SD kind rat ₅₀＞5000mg/kgBW belongs to actual nontoxic level.Subacute toxicity test is not seen illeffects greater than 1000mg/kgBW; Do not see the toxic main target organ of rat subacute (30d) per os.

Claims (2)

1. disinfectant solution is characterized in that component is as follows by weight percentage:

1) iodine 0.1%～1.0%;

2) polyvinylpyrrolidone 0.4%～4.0%;

3) potassium iodide: 0.03%～0.3%;

4) dodecylbenzene sodium sulfonate 0.02%～0.2%;

5) purified water 94.50%～99.45%.

2. according to the disinfectant solution of claim 1, it is characterized in that component is as follows by weight percentage:

1) iodine 0.5%;

2) polyvinylpyrrolidone 2.0%;

3) potassium iodide: 0.15%;

4) dodecylbenzene sodium sulfonate 0.1%;

5) purified water 97.25%.