CN107233358A - A kind of thimerosal - Google Patents
A kind of thimerosal Download PDFInfo
- Publication number
- CN107233358A CN107233358A CN201610510865.1A CN201610510865A CN107233358A CN 107233358 A CN107233358 A CN 107233358A CN 201610510865 A CN201610510865 A CN 201610510865A CN 107233358 A CN107233358 A CN 107233358A
- Authority
- CN
- China
- Prior art keywords
- purified water
- iodine
- thimerosal
- eleventh
- isopropanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/18—Iodine; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention discloses a kind of thimerosal, including dichloro cresols, potassium hydroxide, the eleventh of the twelve Earthly Branches dialdehyde, isopropanol, KI, iodine, neopelex and purified water, and be respectively 2 8%, 2 8%, 2 7%, 6 12%, 0.2 0.5%, 1 2%, 0.05 0.1% by its percentage by weight, remaining is purified water.The component is effective sterilization factors the iodine molecule activation for not possessing bactericidal activity substantially, so both substantially increase fungicidal effectiveness, it turn avoid the waste of I, it is that a kind of fungicidal effectiveness is strong, safe, stability is good, and corrosivity and excitant are low, can be used for skin, mucous membrane and wound disinfection and the low thimerosal of available iodine content.The shortcoming that general iodic disinfecting liquid is yellow, viscous, steep can also be overcome.
Description
Technical field
The present invention relates to the medicinal preparation containing inorganic active ingredient, iodine and its compound, espespecially a kind of thimerosal.
Background technology
Most popular detoxicating liquid is to contain iodic disinfecting liquid in current China market, is many using the tincture of iodine, it is well known that iodine belongs to halogen
Race, it has dual character, as a double-edged sword：On the one hand it has the shared Strong oxdiative characteristic of halogen, to bacterial disease
Poison has powerful killing ability, belongs to high-effective disinfecting element.On the other hand it has strong corrosivity and excitant again, only
Skin degerming can be used for, it is impossible to be used in mucous membrane and wound disinfection, if processing is bad, wound will be caused to human body or animal body
Evil.All the time, people have no idea the dual character of iodine processing to an optimal state, i.e.,：Fungicidal effectiveness and peace
Full property all reaches maximization.And the available iodine content of the general tincture of iodine, all more than 2%, this is for iodine resource more and more in short supply
Consumption be very inappropriate.
The content of the invention
It is an object of the invention to provide a kind of security is higher, the preferable thimerosal of stability.
The technical solution adopted by the present invention is：
A kind of thimerosal, its innovative point is：Including dichloro cresols, potassium hydroxide, the eleventh of the twelve Earthly Branches dialdehyde, isopropanol, KI, iodine, ten
Dialkyl benzene sulfonic acids sodium and purified water, and be respectively 2-8%, 2-8%, 2-7%, 6-12%, 0.2-0.5%, 1- by its percentage by weight
2%th, 0.05-0.1%, remaining is purified water.
Further, including dichloro cresols, potassium hydroxide, the eleventh of the twelve Earthly Branches dialdehyde, isopropanol, KI, iodine, DBSA
Sodium and purified water, and be respectively 3-7%, 4-6%, 3-6%, 6-10%, 0.2-0.4%, 1-2%, 0.06- by its percentage by weight
0.08%, remaining is purified water.
Further, including dichloro cresols, potassium hydroxide, the eleventh of the twelve Earthly Branches dialdehyde, isopropanol, KI, iodine, DBSA
Sodium and purified water, and be respectively 5%, 5%, 4%, 8%, 0.3%, 1.5%, 0.07% by its percentage by weight, remaining is purified water.
Beneficial effects of the present invention are as follows：
The component is effective sterilization factors the iodine molecule activation for not possessing bactericidal activity substantially, has so both substantially increased sterilization
Effect, turn avoid the waste of I, be that a kind of fungicidal effectiveness is strong, safe, stability is good, and corrosivity and excitant
It is low, skin, mucous membrane and wound disinfection and the low thimerosal of available iodine content can be used for.Can also overcome general iodic disinfecting liquid it is yellow,
Viscous, bubble shortcoming.
Embodiment
Embodiments of the present invention are illustrated by particular specific embodiment below, those skilled in the art can be by this explanation
Content disclosed by book understands other advantages and effect of the present invention easily.
Embodiment 1
A kind of thimerosal, including dichloro cresols, potassium hydroxide, the eleventh of the twelve Earthly Branches dialdehyde, isopropanol, KI, iodine, neopelex
And purified water, and be respectively 2-8%, 2%, 2%, 6%, 0.2%, 1%, 0.05% by its percentage by weight, remaining is purified water.
Embodiment 2
A kind of thimerosal, including dichloro cresols, potassium hydroxide, the eleventh of the twelve Earthly Branches dialdehyde, isopropanol, KI, iodine, neopelex
And purified water, and be respectively 8%, 8%, 7%, 12%, 0.5%, 2%, 0.1% by its percentage by weight, remaining is purified water.
Embodiment 3
A kind of thimerosal, including dichloro cresols, potassium hydroxide, the eleventh of the twelve Earthly Branches dialdehyde, isopropanol, KI, iodine, neopelex
And purified water, and be respectively 5%, 5%, 4%, 8%, 0.3%, 1.5%, 0.07% by its percentage by weight, remaining is purified water.
Described above is the preferred embodiment of the present invention, it is impossible to the interest field of the present invention is limited with this.It should refer to
Go out, for those skilled in the art, technical scheme is modified or equivalent substitution, all
Protection scope of the present invention is not departed from.
Claims (3)
1. a kind of thimerosal, it is characterised in that：Including dichloro cresols, potassium hydroxide, the eleventh of the twelve Earthly Branches dialdehyde, isopropanol, KI, iodine, ten
Dialkyl benzene sulfonic acids sodium and purified water, and be respectively 2-8%, 2-8%, 2-7%, 6-12%, 0.2-0.5%, 1- by its percentage by weight
2%th, 0.05-0.1%, remaining is purified water.
2. a kind of thimerosal according to claim 1, it is characterised in that：Including dichloro cresols, potassium hydroxide, the eleventh of the twelve Earthly Branches dialdehyde,
Isopropanol, KI, iodine, neopelex and purified water, and be respectively 3-7%, 4-6%, 3- by its percentage by weight
6%th, 6-10%, 0.2-0.4%, 1-2%, 0.06-0.08%, remaining is purified water.
3. a kind of thimerosal according to claim 1, it is characterised in that：Including dichloro cresols, potassium hydroxide, the eleventh of the twelve Earthly Branches dialdehyde,
Isopropanol, KI, iodine, neopelex and purified water, and by its percentage by weight be respectively 5%, 5%, 4%, 8%,
0.3%th, 1.5%, 0.07%, remaining is purified water.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610510865.1A CN107233358A (en) | 2016-07-04 | 2016-07-04 | A kind of thimerosal |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610510865.1A CN107233358A (en) | 2016-07-04 | 2016-07-04 | A kind of thimerosal |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107233358A true CN107233358A (en) | 2017-10-10 |
Family
ID=59983423
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610510865.1A Pending CN107233358A (en) | 2016-07-04 | 2016-07-04 | A kind of thimerosal |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107233358A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112023088A (en) * | 2020-09-29 | 2020-12-04 | 湖北君言医疗科技有限公司 | Disinfection process for processing medical transparent dressing |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101926369A (en) * | 2009-06-19 | 2010-12-29 | 王慧娟 | Disinfectant solution |
-
2016
- 2016-07-04 CN CN201610510865.1A patent/CN107233358A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101926369A (en) * | 2009-06-19 | 2010-12-29 | 王慧娟 | Disinfectant solution |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112023088A (en) * | 2020-09-29 | 2020-12-04 | 湖北君言医疗科技有限公司 | Disinfection process for processing medical transparent dressing |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO2008153077A1 (en) | Anti-norovirus agent, and composition comprising the same | |
| US5322856A (en) | Fortified glutaraldehyde chemical sterilant/disinfectant | |
| CN103891727A (en) | Preparation method of stable compound halogen organic disinfectant | |
| CN108653121A (en) | A kind of antibacterial type disinfecting liquid containing medicinal herb components | |
| KR101355702B1 (en) | Environment-friendly disinfectant composition | |
| CN107233358A (en) | A kind of thimerosal | |
| Sadiq et al. | Pharmaceutical Importance of Anti-Microbials | |
| US5252606A (en) | Fortified glutaraldehyde disinfectant | |
| CN101006782A (en) | Preparation method of a stable high potential chlorine-containing disinfection liquid | |
| CN103283722A (en) | Compound disinfectant for hospital and application thereof | |
| CN101897332A (en) | Compound formalin disinfectant | |
| BR0114318A (en) | Hard Surface Cleaning & Disinfectants | |
| EP2384623A1 (en) | Powder composition for the prevention and treatment of animal hoof diseases | |
| CN112370439A (en) | Preparation method of disinfectant | |
| CN101862347A (en) | Disinfectant | |
| CN103814896B (en) | Disinfectant and wet tissue prepared from same | |
| CN105010351A (en) | Compound disinfectant | |
| WO2013083612A1 (en) | Powder composition for the disinfection of ungulates' baths | |
| RU2165267C1 (en) | Method of combating aspergillosis when disinfecting cattle-breading rooms | |
| CN104970041A (en) | Disinfector | |
| CN109832293A (en) | A kind of medical bactericide | |
| CN109832298A (en) | A kind of medical sterilization formulation | |
| CN101743971A (en) | Compound disinfector of peroxyacetic acid and glutaric dialdehyde | |
| JP3519991B2 (en) | Method for producing neutral silver ionized water | |
| CN106577800A (en) | Efficient-decontaminating kitchen disinfection liquid |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20171010 |
|
| WD01 | Invention patent application deemed withdrawn after publication |