CN101856420A - Medicament for removing stains and preparation method thereof - Google Patents

Abstract

The invention relates to capsules or pasty juice for removing stains, which are/is prepared from Chinese medicinal herbs. The capsules or the pasty juice are/is prepared by the following steps of: mixing Chinese angelica, Szechuan lovage rhizome, red paeony root, rehmannia root, peach seed, safflower, two-tooth achyranthes root, bupleurum root, immature bitter orange, liquorice root and mulberry leaves uniformly, then putting the mixture into a container, decocting the mixture by adding clean water, and extracting filtrate; adding maltose into the extract, and mixing and stirring the maltose and the extract uniformly to obtain the pasty juice; or drying the pasty juice, then crushing the dried product into fine powder, sterilizing the fine powder, and preparing a capsule product. The capsules or the pasty juice have/has the characteristics of soothing liver-qi stagnation, regulating incretion and effectively removing the stains.

Description

Medicine of a kind of dispelling stain and preparation method thereof

Technical field

The present invention relates to a kind of medicine, being specifically related to a kind of is the medicine of the dispelling stain of feedstock production with Chinese medicine.The invention still further relates to the preparation method of this medicine.

Background technology

Mottle comprises freckle, black speck, chloasma and senile plaque etc., belongs to pigment obstacle dermatoses.Freckle: the autosomal dominant inheritance, AD dermatoses, occur when often young, be more common in exposure portion such as teenager face, neck, the back of the hand, be filbert or dark brown speckle, be dispersed in symmetrical distribution more, have genetic predisposition; Spring and summer increases the weight of, the autumn and winter shoal.Chloasma: be a kind of posteriority limitation hyperpigmentation disease, be common skin disease the most in a kind of women crowd, conceived the 2nd～5 month women especially is to claim butterfly spot, cyasma, chloasma hepaticum etc., these are several to be with a kind of disease, names according to differences such as form, age bracket features.A common ground of these diseases is endocrine regulations, and drainage difficulty is subjected to infection of bacterial virus or the dermatosis that the toxin calmness causes.Modern Chinese and western medicine provides multiple medicine to above disease, have for oral administration, washout or freezing, operative treatments such as laser, but the overwhelming majority takes effect slowly, costs an arm and a leg, and easily recurrence can not effectively be treated the various skin disease while, do not satisfy patient's demand.

Summary of the invention

The objective of the invention is to bring into play traditional Chinese medical science combination drug, a kind of dispersing the stagnated live-QI to relieve the stagnation of QI is provided, endocrine regulation, instant effect has no side effect, few recurrence, the medicine of low-cost dispelling stain.

Another goal of the invention of the present invention provides the preparation method of this medicine.

Based on above-mentioned Therapeutic Principle, medicine of the present invention is to be crude drug with following parts of medicines by weight:

Radix Angelicae Sinensis 10～20, Rhizoma Chuanxiong 10～20, Radix Paeoniae Rubra 10～20, the Radix Rehmanniae 10～20, Semen Persicae 10～15, Flos Carthami 10～20, Radix Achyranthis Bidentatae 10～15, Radix Bupleuri 10～15, Fructus Aurantii Immaturus 10～20, Radix Glycyrrhizae 10～20, Folium Mori 15～30, maltose 30～50.

Said medicine can be made any dosage form on the pharmaceutics, as decoction, tablet, pill, powder, capsule, cream juice;

The preferred dosage form of the present invention is capsule, cream juice.

Concrete preparation method comprises that the following step poly-:

1) with Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, the Radix Rehmanniae, Semen Persicae, Flos Carthami, Radix Achyranthis Bidentatae, Radix Bupleuri, Fructus Aurantii Immaturus, Radix Glycyrrhizae, Folium Mori, behind above-mentioned parts by weight mix homogeneously, place in the container, the clear water that adds 3～8 times decocts 0.5～3 hour extraction filtrate;

2) maltose with 30～50 parts by weight adds in the filtrate of extracting, and mixing and stirring makes cream juice.

The present invention is further, 1) with Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, the Radix Rehmanniae, Semen Persicae, Flos Carthami, Radix Achyranthis Bidentatae, Radix Bupleuri, Fructus Aurantii Immaturus, Radix Glycyrrhizae, Folium Mori, behind above-mentioned parts by weight mix homogeneously, place in the container, the clear water that adds 3～8 times decocts 0.5～3 hour extraction filtrate;

2) maltose with 30～50 parts by weight adds in the filtrate of extracting, and mixing and stirring is made cream juice;

3) with cream juice drying, be ground into 100～120 purpose fine powders then, sterilization is made capsule product.

The present invention has dispersing the stagnated live-QI to relieve the stagnation of QI, endocrine regulation, and instant effect has no side effect, few recurrence, advantages such as low price.

In the prescription of the present invention, Radix Angelicae Sinensis: property Gan Xinwen, return liver heart spleen channel, have and enrich blood, invigorate blood circulation pain relieving, the effect of profit field; Rhizoma Chuanxiong: Xin Wen has blood-activating and qi-promoting, wind-expelling pain-stopping; Radix Paeoniae Rubra: bitter, be slightly cold clearing away heat and cooling blood, stasis-dispelling and pain-killing; The Radix Rehmanniae: be used for consumption of YIN caused by febrile disease, the crimson tongue excessive thirst is sent out the speckle dermexanthesis, spits blood, and epistaxis, laryngopharynx swelling and pain, clearing away heat and cooling blood, yin nourishing is promoted the production of body fluid.Semen Persicae: bitter, flat have a blood circulation promoting and blood stasis dispelling, the effect of loosening bowel to relieve constipation; Flos Carthami: have blood circulation promoting and blood stasis dispelling, the effect of stimulating the menstrual flow, it is dark to be used for the macule color; Radix Achyranthis Bidentatae: invigorating the liver and kidney; Bone and muscle strengthening; Promoting blood circulation to restore menstrual flow; Radix Bupleuri: bitter, hot, be slightly cold reducing fever by reconciliation, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy; Fructus Aurantii Immaturus: bitter, hot, be slightly cold, the dispelling the stagnated QI removing food stagnancy reduces phlegm except that painful abdominal mass; Radix Glycyrrhizae: sweet, flat, have invigorating the spleen and replenishing QI, nourishing the lung to arrest cough, relieving spasm to stop pain relaxes the effect of the property of medicine; Folium Mori: sweet, bitter, cold.Dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, above each the medicine compatibility of liver heat removing and eyesight improving forms, and has dispersing the stagnated live-QI to relieve the stagnation of QI, endocrine regulation, the effect of speckle dispelling repercussive.Be used for anemopyretic cold, lung-heat type cough, dizziness headache, conjunctival congestion is dim-sighted

The present invention enriches blood with it and invigorates blood circulation, and the stasis-resolving spot-removing effect is a purpose, uses Radix Angelicae Sinensis in a large number, Flos Carthami, and outstanding enriching blood invigorated blood circulation and with the Radix Bupleuri soothing liver-QI for relieving depression, the elevate a turnable ladder yang-energy strengthens the purpose of drug effect.

For showing the present invention to because of QI and blood deficiency, the therapeutic effect of male sexual dysfunction that the endocrine disturbance causes, the clinical use final report of the present invention following table finding:

Table one: the comparison of short term effect between treatment group and matched group

Annotate: the treatment group: because of QI and blood deficiency, the endocrine disturbance causes female color spot disease treatment group

Matched group: the group of not using treatment by Chinese herbs

Table two: toxic reaction compares (WHO) between treatment group and matched group

The specific embodiment

Embodiment 1:

Take by weighing raw material by following proportioning:

Radix Angelicae Sinensis 10g, Rhizoma Chuanxiong 10g, Radix Paeoniae Rubra 10g, Radix Rehmanniae 10g, Semen Persicae 10g, Flos Carthami 10g, Radix Achyranthis Bidentatae 10g, Radix Bupleuri 10g, Fructus Aurantii Immaturus 10g, Radix Glycyrrhizae 10g, Folium Mori 15g, maltose 30g.

Concrete preparation method comprises that the following step poly-:

1) with Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, the Radix Rehmanniae, Semen Persicae, Flos Carthami, Radix Achyranthis Bidentatae, Radix Bupleuri, Fructus Aurantii Immaturus, Radix Glycyrrhizae, Folium Mori, behind above-mentioned parts by weight mix homogeneously, place in the container, the clear water that adds 3 times decocts 1 hour extraction filtrate;

2) maltose with 30g adds in the filtrate of extracting, and mixing and stirring makes cream juice.

Embodiment 2:

Take by weighing raw material by following proportioning:

Radix Angelicae Sinensis 20g, Rhizoma Chuanxiong 20g, Radix Paeoniae Rubra 20g, Radix Rehmanniae 20g, Semen Persicae 15g, Flos Carthami 20g, Radix Achyranthis Bidentatae 15g, Radix Bupleuri 15g, Fructus Aurantii Immaturus 20g, Radix Glycyrrhizae 20g, Folium Mori 30g, maltose 50g.

Concrete preparation method comprises that the following step poly-:

1) with Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, the Radix Rehmanniae, Semen Persicae, Flos Carthami, Radix Achyranthis Bidentatae, Radix Bupleuri, Fructus Aurantii Immaturus, Radix Glycyrrhizae, Folium Mori, behind the mix homogeneously, place in the container, the clear water that adds 8 times decocts 3 hours extraction filtrate;

2) maltose with 50g adds in the filtrate of extracting, and mixing and stirring makes cream juice;

3) with cream juice drying, be ground into 110 purpose fine powders then, sterilization is made capsule product.

Claims (6)

1. the medicine of a dispelling stain is characterized in that with following parts of medicines by weight be crude drug:

Radix Angelicae Sinensis 10～20, Rhizoma Chuanxiong 10～20, Radix Paeoniae Rubra 10～20, the Radix Rehmanniae 10～20, Semen Persicae 10～15, Flos Carthami 10～20, Radix Achyranthis Bidentatae 10～15, Radix Bupleuri 10～15, Fructus Aurantii Immaturus 10～20, Radix Glycyrrhizae 10～20, Folium Mori 15～30, maltose 30～50.

2. the medicine of a kind of dispelling stain according to claim 1, it is characterized in that: described medicament is a said dosage form on any pharmaceutics.

3. the medicine of a kind of dispelling stain according to claim 1, it is characterized in that: described medicament is a cream juice.

4. the medicine of a kind of dispelling stain according to claim 1, it is characterized in that: described medicament is a capsule.

5. the preparation method of the medicine of a kind of dispelling stain according to claim 3 is characterized in that: may further comprise the steps:

1) with Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, the Radix Rehmanniae, Semen Persicae, Flos Carthami, Radix Achyranthis Bidentatae, Radix Bupleuri, Fructus Aurantii Immaturus, Radix Glycyrrhizae, Folium Mori, behind above-mentioned parts by weight mix homogeneously, place in the container, the clear water that adds 3～8 times decocts 0.5～3 hour extraction filtrate;

2) maltose with 30～50 parts by weight adds in the filtrate of extracting, and mixing and stirring makes cream juice.

6. the preparation method of the medicine of a kind of dispelling stain according to claim 4 is characterized in that: may further comprise the steps:

1) with Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, the Radix Rehmanniae, Semen Persicae, Flos Carthami, Radix Achyranthis Bidentatae, Radix Bupleuri, Fructus Aurantii Immaturus, Radix Glycyrrhizae, Folium Mori, behind above-mentioned parts by weight mix homogeneously, place in the container, the clear water that adds 3～8 times decocts 0.5～3 hour extraction filtrate;

2) maltose with 30～50 parts by weight adds in the filtrate of extracting, and mixing and stirring is made cream juice;

3) with cream juice drying, be ground into 100～120 purpose fine powders then, sterilization is made capsule product.