CN101850087A - Medicinal composition used for alleviating pains and preparation method and application thereof - Google Patents
Medicinal composition used for alleviating pains and preparation method and application thereof Download PDFInfo
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Abstract
The invention belongs to the field of medicaments, and particularly relates to a medicinal composition used for alleviating pains and a preparation method and application thereof. The invention provides a brand-new medicinal composition used for alleviating the pains. The medicinal composition is prepared from the following raw medicinal materials in part by weight: 5 to 9 parts of rhizoma corydalis, 3 to 5 parts of hiraute shiny bugleweed herb, 3 to 5 parts of pyrite, 2 to 5 parts of henbane seed, 3 to 5 parts of dragon's blood, 5 to 7 parts of frankincense, 5 to 7 parts of myrrh, 3 to 5 parts of zedoary, 3 to 5 parts of common burreed rhizome, 5 to 7 parts of safflower, 5 to 9 parts of Chinese angelica, 3 to 7 parts of rhubarb, and 3 to 7 parts of combined spicebush root. For external use, the medicinal composition can be used for treating various pains caused by acute soft tissue sprain and contusion, chronic appendicitis, traumatic hematoma, hyperosteogeny of cervical vertebra and lumbar vertebrae, protrusion of intervertebral disc, scapulohumeral periarthritis, ischiatitis, cancerous protuberances, dysmenorrhea, healing after fracture and the like, and has an obvious effect of alleviating the pains.
Description
Technical field
The invention belongs to field of medicaments, be specifically related to be used for analgesic pharmaceutical composition and its production and use.
Background technology
The pain a kind of offending reaction that to be body produce damaged tissue or potential damage is a kind of complex physical mental activity, is one of modal symptom clinically.It comprises that noxious stimulation acts on the caused pain of body and feels, and body is to the pain reaction (somatic movement reaction and/or internal organs vegetative reaction often are attended by intensive emotion color) of noxious stimulation.The pain sensation can be used as a kind of warning that body comes to harm, and causes the protective reaction of body series of defence.But then, pain also has its limitation (when pain occurring as cancer etc., coming too late) as reporting to the police.And some secular having an intense pain has become a kind of insufferable torment to body.Therefore, the analgesia pain relieving is the vital task that the medical personnel faces.
Analgesic commonly used at present mainly contains following a few class: the first kind is the non-steroidal analgesic, represents medicine that aspirin and ibuprofen etc. are arranged; This type of medicine has the possibility of the gastrorrhagia of causing, so there is the patient of serious gastropathy to be not suitable for using.Second class is to be the maincenter analgesic of representative with the tramadol; This type of medicine stimulates less for gastrointestinal, and does not have addiction, can select for use for the patient that can't tolerate non-steroidal drug, but its analgesic effect is stronger, can only be as two wires choice of drug.The 3rd class is an opium analgesics, as dolantin, morphine etc.; This type of medicine analgesic activity is powerful, and extremely strong addiction is arranged, and therefore only is used for the bullate patient's pain relieving of advanced carcinoma.
Also there is at present the method for a lot of employing tcm treatment according to syndrome differentiation to be used for pain relieving analgesic report, as a kind of externally applied anticancer analgesic ointment of Chinese patent application (publication number CN1375305A), be furnished with Radix Aconiti, Radix Aconiti Kusnezoffii, Spica Prunellae, punt-pole, Semen Hyoscyami, Rhizoma Corydalis, Semen Momordicae, Radix Tripterygii Wilfordii, Semen Strychni, Rhizoma Arisaematis, Daphne giraldii Nitsche, toad clam, Rhizoma Paridis, Resina garciniae, Resina Ferulae, Borneolum Syntheticum, vegetable oil in its component, drying pulverizing, high-temp extracting, mixing boil and form; This medicine has effects such as pain relieving is rapid-action, pain relieving longer duration, anti-inflammation detumescence.Be applicable to various in, pain diseases such as cancer pain at late stage and angina pectoris, cyclomastopathy, hyperosteogeny, tooth swelling around the eyes pain, innominate toxic swelling.
Summary of the invention
Technical problem solved by the invention provides a kind of brand-new medicinal composition and is used for pain relieving.
Pharmaceutical composition of the present invention is to be prepared from by following materials of weight proportions medicine: Rhizoma Corydalis 5-9 part, Herba Lycopi 3-5 part, Pyritum 3-5 part, Semen Hyoscyami 2-5 part, Sanguis Draxonis 3-5 part, Olibanum 5-7 part, Myrrha 5-7 part, Rhizoma Curcumae 3-5 part, rhizoma sparganic 3-5 part, Flos Carthami 5-7 part, Radix Angelicae Sinensis 5-9 part, Radix Et Rhizoma Rhei 3-7 part, Radix Linderae 3-7 part.
Further preferred: 6 parts of Rhizoma Corydalis, 4 parts of Herba Lycopi, 3 parts of Pyritums, 2 parts of Semen Hyoscyamis, 4 parts of Sanguis Draxonis, 7 parts of Olibanums, 7 parts of Myrrhas, 5 parts of Rhizoma Curcumae, 5 parts of rhizoma sparganic, 6 parts on Flos Carthami, 7 parts of Radix Angelicae Sinensis, 6 parts of Radix Et Rhizoma Rhei, 3 parts of the Radixs Linderae.
External pharmaceutical composition of the present invention can be used for treating various pain, as the acute soft tissue bruise, and chronic strain, wound hematoma, neck, lumbar vertebra hyperosteogeny disease, intervertebral disc prolapse, scapulohumeral periarthritis, sciatic neuritis, cancerous protuberance, dysmenorrhea, fracture back healing etc., relieving pain.
The present invention also provides this preparation of drug combination method.
A, weighting raw materials: Rhizoma Corydalis 5-9 part, Herba Lycopi 3-5 part, Pyritum 3-5 part, Semen Hyoscyami 2-5 part, Sanguis Draxonis 3-5 part, Olibanum 5-7 part, Myrrha 5-7 part, Rhizoma Curcumae 3-5 part, rhizoma sparganic 3-5 part, Flos Carthami 5-7 part, Radix Angelicae Sinensis 5-9 part, Radix Et Rhizoma Rhei 3-7 part, Radix Linderae 3-7 part;
Or weighting raw materials: Rhizoma Corydalis 5-9 part, Daphne giraldii Nitsche 3-7 part, Herba Aristolochiae Mollissimae 3-5 part, Semen Hyoscyami 2-5 part, Herba Lycopodii 3-5 part, Fructus Chaenomelis 3-5 part, Herba Lycopi 3-5 part, Pyritum 3-5 part, Lignum Sappan 5-7 part, Sanguis Draxonis 3-5 part, Rhizoma Curcumae Longae 5-7 part, Olibanum 5-7 part, Myrrha 5-7 part, rhizoma sparganic 3-5 part, Flos Carthami 5-7 part, Semen Persicae 5-7 part, Radix Angelicae Sinensis 5-9 part, Radix Et Rhizoma Rhei 3-7 part, Rhizoma Curcumae 3-5 part, Radix Linderae 3-7 part;
B, Olibanum, Myrrha are ground into fine powder, with Pyritum facing-up, the mixing that sieves, powder is standby; After all the other crude drug are pulverized or are cut off, fried withered with edible oil with placing in the pot, remove slag, filter, refining is to dripping into pearl; Get Plumbum preparatium, the ratio that adds 150-210g Plumbum preparatium in every 500g edible oil adds in the edible oil, stirs evenly, and receives cream, and cream is soaked in the water; Get cream,, add above-mentioned standby powder, stir evenly, share on cloth, that is, make plaster with the slow fire fusing.
Or Olibanum, Myrrha be ground into fine powder, with Pyritum facing-up, the mixing that sieves, powder is standby; All the other crude drug waters decoct, and filter, and get decocting liquid; The water intaking decocting liquid adds acceptable accessories and above-mentioned standby powder according to a conventional method, makes external preparation.
This method adopts reasonable method extraction main active wherein according to the characteristic of crude drug, makes therapeutic effect more stable, controlled.
The specific embodiment
Below by specific description of embodiments of the present invention the explanation but do not limit the present invention.
Pharmaceutical composition of the present invention is to be prepared from by following materials of weight proportions medicine: Rhizoma Corydalis 5-9 part, Herba Lycopi 3-5 part, Pyritum 3-5 part, Semen Hyoscyami 2-5 part, Sanguis Draxonis 3-5 part, Olibanum 5-7 part, Myrrha 5-7 part, Rhizoma Curcumae 3-5 part, rhizoma sparganic 3-5 part, Flos Carthami 5-7 part, Radix Angelicae Sinensis 5-9 part, Radix Et Rhizoma Rhei 3-7 part, Radix Linderae 3-7 part.Active component floats in this amount ranges and all can realize analgesia, aim of alleviating pain.
Find that through inventor's long-term practice 6 parts of Rhizoma Corydalis, 4 parts of Herba Lycopi, 3 parts of Pyritums, 2 parts of Semen Hyoscyamis, 4 parts of Sanguis Draxonis, 7 parts of Olibanums, 7 parts of Myrrhas, 5 parts of Rhizoma Curcumae, 5 parts of rhizoma sparganic, 6 parts on Flos Carthami, 7 parts of Radix Angelicae Sinensis, 6 parts of Radix Et Rhizoma Rhei, 3 parts of effects of the Radix Linderae are clearer and more definite, more stable.
Further preferred, in order to strengthen, stablize curative effect, crude drug also contains Daphne giraldii Nitsche, Herba Aristolochiae Mollissimae, Herba Lycopodii, Fructus Chaenomelis, Lignum Sappan, Rhizoma Curcumae Longae, Semen Persicae, and the crude drug weight proportion is as follows:
Rhizoma Corydalis 5-9 part, Daphne giraldii Nitsche 3-7 part, Herba Aristolochiae Mollissimae 3-5 part, Semen Hyoscyami 2-5 part, Herba Lycopodii 3-5 part, Fructus Chaenomelis 3-5 part, Herba Lycopi 3-5 part, Pyritum 3-5 part, Lignum Sappan 5-7 part, Sanguis Draxonis 3-5 part, Rhizoma Curcumae Longae 5-7 part, Olibanum 5-7 part, Myrrha 5-7 part, rhizoma sparganic 3-5 part, Flos Carthami 5-7 part, Semen Persicae 5-7 part, Radix Angelicae Sinensis 5-9 part, Radix Et Rhizoma Rhei 3-7 part, Rhizoma Curcumae 3-5 part, Radix Linderae 3-7 part.
Further preferred, the above-mentioned raw materials medicine adopts following materials of weight proportions medicine clearer and more definite, more stable: 6 parts of Rhizoma Corydalis, 3 parts of Daphne giraldii Nitsche, 4 parts of Herba Aristolochiae Mollissimaes, 2 parts of Semen Hyoscyamis, 3 parts of Herba Lycopodiis, 3 parts of Fructus Chaenomeliss, 4 parts of Herba Lycopi, 3 parts of Pyritums, 5 parts of Lignum Sappans, 4 parts of Sanguis Draxonis, 5 parts in Rhizoma Curcumae Longae, 7 parts of Olibanums, 7 parts of Myrrhas, 5 parts of rhizoma sparganic, 6 parts on Flos Carthami, 7 parts in Semen Persicae, 7 parts of Radix Angelicae Sinensis, 6 parts of Radix Et Rhizoma Rhei, 5 parts of Rhizoma Curcumae, 3 parts of the Radixs Linderae.
For the ease of using, can on the basis of crude drug, add acceptable accessories and make external preparation commonly used.As ointment, plaster.Plaster can be made into diachylon, rubber plaster, cataplasma or transdermal patch.
External pharmaceutical composition of the present invention can be used for treating various pain, as the acute soft tissue bruise, and chronic strain, wound hematoma, neck, lumbar vertebra hyperosteogeny disease, intervertebral disc prolapse, scapulohumeral periarthritis, sciatic neuritis, cancerous protuberance, dysmenorrhea, fracture back healing etc., relieving pain.
Below beneficial effect by clinical statistics proof pharmaceutical composition of the present invention.
It is clinical that the inventor adopts pharmaceutical composition of the present invention to be applied to, and specifically is to be made into plaster to use, and the plaster preparation method is as follows:
1, with the weight ratio weighting raw materials of 6 parts of Rhizoma Corydalis, 4 parts of Herba Lycopi, 3 parts of Pyritums, 2 parts of Semen Hyoscyamis, 4 parts of Sanguis Draxonis, 7 parts of Olibanums, 7 parts of Myrrhas, 5 parts of Rhizoma Curcumae, 5 parts of rhizoma sparganic, 6 parts on Flos Carthami, 7 parts of Radix Angelicae Sinensis, 6 parts of Radix Et Rhizoma Rhei, 3 parts of the Radixs Linderae, Olibanum, Myrrha are ground into fine powder, with the Pyritum facing-up, the mixing that sieves, standby; After all the other crude drug are pulverized or are cut off, fried withered with edible oil (Oleum Sesami) with placing in the pot, remove slag, filter, refining is to dripping into pearl; Get Plumbum preparatium, the ratio that adds 200g Plumbum preparatium in every 500g edible oil adds in the oil, stirs evenly, and receives cream, and cream is soaked in the water; Get cream,, add standby powder, stir evenly, share on cloth, that is, make plaster A with the slow fire fusing.
2, with the weight ratio weighting raw materials of 6 parts of Rhizoma Corydalis, 3 parts of Daphne giraldii Nitsche, 4 parts of Herba Aristolochiae Mollissimaes, 2 parts of Semen Hyoscyamis, 3 parts of Herba Lycopodiis, 3 parts of Fructus Chaenomeliss, 4 parts of Herba Lycopi, 3 parts of Pyritums, 5 parts of Lignum Sappans, 4 parts of Sanguis Draxonis, 5 parts in Rhizoma Curcumae Longae, 7 parts of Olibanums, 7 parts of Myrrhas, 5 parts of rhizoma sparganic, 6 parts on Flos Carthami, 7 parts in Semen Persicae, 7 parts of Radix Angelicae Sinensis, 6 parts of Radix Et Rhizoma Rhei, 5 parts of Rhizoma Curcumae, 3 parts of the Radixs Linderae, Olibanum, Myrrha are ground into fine powder, with the Pyritum facing-up, the mixing that sieves, standby; After all the other crude drug are pulverized or are cut off, fried withered with edible oil (Oleum Sesami) with placing in the pot, remove slag, filter, refining is to dripping into pearl; Get Plumbum preparatium, the ratio that adds 200g Plumbum preparatium in every 500g edible oil adds in the oil, stirs evenly, and receives cream, and cream is soaked in the water; Get cream,, add standby powder, stir evenly, share on cloth, that is, make plaster B with the slow fire fusing.
Use plaster A and B and be used for analgesia, pain relieving, during use, plaster after bakingization, directly is affixed on pain spot (locating), the analgesic effect statistical data sees Table 1-9:
Table 1
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Table 3
Table 4
Table 5
Table 6
Table 7
Table 8
Table 9
Claims (10)
1. be used for the analgesic pharmaceutical composition, it is characterized in that: it is to be prepared from by following materials of weight proportions medicine:
Rhizoma Corydalis 5-9 part, Herba Lycopi 3-5 part, Pyritum 3-5 part, Semen Hyoscyami 2-5 part, Sanguis Draxonis 3-5 part, Olibanum 5-7 part, Myrrha 5-7 part, Rhizoma Curcumae 3-5 part, rhizoma sparganic 3-5 part, Flos Carthami 5-7 part, Radix Angelicae Sinensis 5-9 part, Radix Et Rhizoma Rhei 3-7 part, Radix Linderae 3-7 part.
2. the analgesic pharmaceutical composition that is used for according to claim 1 is characterized in that: it is to be prepared from by following materials of weight proportions medicine:
6 parts of Rhizoma Corydalis, 4 parts of Herba Lycopi, 3 parts of Pyritums, 2 parts of Semen Hyoscyamis, 4 parts of Sanguis Draxonis, 7 parts of Olibanums, 7 parts of Myrrhas, 5 parts of Rhizoma Curcumae, 5 parts of rhizoma sparganic, 6 parts on Flos Carthami, 7 parts of Radix Angelicae Sinensis, 6 parts of Radix Et Rhizoma Rhei, 3 parts of the Radixs Linderae.
3. the analgesic pharmaceutical composition that is used for according to claim 1, it is characterized in that: it is to be crude drug with Rhizoma Corydalis, Herba Lycopi, Pyritum, Semen Hyoscyami, Sanguis Draxonis, Olibanum, Myrrha, Rhizoma Curcumae, rhizoma sparganic, Flos Carthami, Radix Angelicae Sinensis, Radix Et Rhizoma Rhei, the Radix Linderae, adds the medicament that acceptable accessories is prepared from.
4. the analgesic pharmaceutical composition that is used for according to claim 1, it is characterized in that: crude drug also contains Daphne giraldii Nitsche, Herba Aristolochiae Mollissimae, Herba Lycopodii, Fructus Chaenomelis, Lignum Sappan, Rhizoma Curcumae Longae, Semen Persicae, and the crude drug weight proportion is as follows:
Rhizoma Corydalis 5-9 part, Daphne giraldii Nitsche 3-7 part, Herba Aristolochiae Mollissimae 3-5 part, Semen Hyoscyami 2-5 part, Herba Lycopodii 3-5 part, Fructus Chaenomelis 3-5 part, Herba Lycopi 3-5 part, Pyritum 3-5 part, Lignum Sappan 5-7 part, Sanguis Draxonis 3-5 part, Rhizoma Curcumae Longae 5-7 part, Olibanum 5-7 part, Myrrha 5-7 part, rhizoma sparganic 3-5 part, Flos Carthami 5-7 part, Semen Persicae 5-7 part, Radix Angelicae Sinensis 5-9 part, Radix Et Rhizoma Rhei 3-7 part, Rhizoma Curcumae 3-5 part, Radix Linderae 3-7 part.
5. the analgesic pharmaceutical composition that is used for according to claim 4 is characterized in that: it is to be prepared from by following materials of weight proportions medicine:
6 parts of Rhizoma Corydalis, 3 parts of Daphne giraldii Nitsche, 4 parts of Herba Aristolochiae Mollissimaes, 2 parts of Semen Hyoscyamis, 3 parts of Herba Lycopodiis, 3 parts of Fructus Chaenomeliss, 4 parts of Herba Lycopi, 3 parts of Pyritums, 5 parts of Lignum Sappans, 4 parts of Sanguis Draxonis, 5 parts in Rhizoma Curcumae Longae, 7 parts of Olibanums, 7 parts of Myrrhas, 5 parts of rhizoma sparganic, 6 parts on Flos Carthami, 7 parts in Semen Persicae, 7 parts of Radix Angelicae Sinensis, 6 parts of Radix Et Rhizoma Rhei, 5 parts of Rhizoma Curcumae, 3 parts of the Radixs Linderae.
6. the analgesic pharmaceutical composition that is used for according to claim 4, it is characterized in that: it is to be crude drug with Daphne giraldii Nitsche, Rhizoma Corydalis, Herba Aristolochiae Mollissimae, Semen Hyoscyami, Herba Lycopodii, Fructus Chaenomelis, Herba Lycopi, Pyritum, Lignum Sappan, Sanguis Draxonis, Rhizoma Curcumae Longae, Olibanum, Myrrha, rhizoma sparganic, Flos Carthami, Semen Persicae, Radix Angelicae Sinensis, Radix Et Rhizoma Rhei, Rhizoma Curcumae, the Radix Linderae, adds the medicament that acceptable accessories is prepared from.
7. according to claim 3 or the 6 described analgesic pharmaceutical compositions that are used for, it is characterized in that: described medicament is an external preparation.
8. one kind is used for analgesic preparation of drug combination method, it is characterized in that its step is as follows:
A, weighting raw materials: Rhizoma Corydalis 5-9 part, Herba Lycopi 3-5 part, Pyritum 3-5 part, Semen Hyoscyami 2-5 part, Sanguis Draxonis 3-5 part, Olibanum 5-7 part, Myrrha 5-7 part, Rhizoma Curcumae 3-5 part, rhizoma sparganic 3-5 part, Flos Carthami 5-7 part, Radix Angelicae Sinensis 5-9 part, Radix Et Rhizoma Rhei 3-7 part, Radix Linderae 3-7 part;
Or weighting raw materials: Rhizoma Corydalis 5-9 part, Daphne giraldii Nitsche 3-7 part, Herba Aristolochiae Mollissimae 3-5 part, Semen Hyoscyami 2-5 part, Herba Lycopodii 3-5 part, Fructus Chaenomelis 3-5 part, Herba Lycopi 3-5 part, Pyritum 3-5 part, Lignum Sappan 5-7 part, Sanguis Draxonis 3-5 part, Rhizoma Curcumae Longae 5-7 part, Olibanum 5-7 part, Myrrha 5-7 part, rhizoma sparganic 3-5 part, Flos Carthami 5-7 part, Semen Persicae 5-7 part, Radix Angelicae Sinensis 5-9 part, Radix Et Rhizoma Rhei 3-7 part, Rhizoma Curcumae 3-5 part, Radix Linderae 3-7 part;
B, Olibanum, Myrrha are ground into fine powder, with Pyritum facing-up, the mixing that sieves, standby;
After C, all the other crude drug are pulverized or are cut off, fried withered with edible oil with placing in the pot, remove slag, filter, refining is to dripping into pearl;
D, get Plumbum preparatium, the ratio that adds 150-210g Plumbum preparatium in every 500g edible oil adds in the edible oil, stirs evenly, and receives cream, and cream is soaked in the water;
E, get cream,, add the standby powder of step B, stir evenly, share on cloth, that is, make plaster with the slow fire fusing.
9. one kind is used for analgesic preparation of drug combination method, it is characterized in that its step is as follows:
A, weighting raw materials: Rhizoma Corydalis 5-9 part, Herba Lycopi 3-5 part, Pyritum 3-5 part, Semen Hyoscyami 2-5 part, Sanguis Draxonis 3-5 part, Olibanum 5-7 part, Myrrha 5-7 part, Rhizoma Curcumae 3-5 part, rhizoma sparganic 3-5 part, Flos Carthami 5-7 part, Radix Angelicae Sinensis 5-9 part, Radix Et Rhizoma Rhei 3-7 part, Radix Linderae 3-7 part;
Or weighting raw materials: Rhizoma Corydalis 5-9 part, Daphne giraldii Nitsche 3-7 part, Herba Aristolochiae Mollissimae 3-5 part, Semen Hyoscyami 2-5 part, Herba Lycopodii 3-5 part, Fructus Chaenomelis 3-5 part, Herba Lycopi 3-5 part, Pyritum 3-5 part, Lignum Sappan 5-7 part, Sanguis Draxonis 3-5 part, Rhizoma Curcumae Longae 5-7 part, Olibanum 5-7 part, Myrrha 5-7 part, rhizoma sparganic 3-5 part, Flos Carthami 5-7 part, Semen Persicae 5-7 part, Radix Angelicae Sinensis 5-9 part, Radix Et Rhizoma Rhei 3-7 part, Rhizoma Curcumae 3-5 part, Radix Linderae 3-7 part;
B, Olibanum, Myrrha are ground into fine powder, with Pyritum facing-up, the mixing that sieves, powder is standby;
C, all the other crude drug waters decoct, and filter, and get decocting liquid;
D, water intaking decocting liquid add acceptable accessories and the standby powder of step B according to a conventional method, make external preparation.
10. each described pharmaceutical composition of claim 1-7 is at preparation treatment acute soft tissue bruise, and chronic strain is sprained and swollen and ache, root cervical spondylosis, prolapse of lumbar intervertebral disc, scapulohumeral periarthritis, sciatica, cancerous protuberance, dysmenorrhea, pains such as fracture back.
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| CN102205091A (en) * | 2011-05-17 | 2011-10-05 | 成都神黄医药科技开发有限公司 | Pharmaceutical composition for treating pain syndrome or arthralgia syndrome and preparation method and application thereof |
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| CN102205091A (en) * | 2011-05-17 | 2011-10-05 | 成都神黄医药科技开发有限公司 | Pharmaceutical composition for treating pain syndrome or arthralgia syndrome and preparation method and application thereof |
| CN102205091B (en) * | 2011-05-17 | 2012-09-19 | 成都神黄医药科技开发有限公司 | Pharmaceutical composition for treating pain syndrome or arthralgia syndrome and preparation method and application thereof |
| CN102552809A (en) * | 2012-01-16 | 2012-07-11 | 王道远 | Externally-used medical liquor for clearing and activating channels and collaterals |
| CN102552809B (en) * | 2012-01-16 | 2013-11-20 | 王道远 | Externally-used medical liquor for clearing and activating channels and collaterals |
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| CN102579978B (en) * | 2012-02-28 | 2013-11-27 | 矫俊东 | External traditional Chinese medicine composition for treating scapulohumeral periarthritis |
| CN102940754A (en) * | 2012-12-11 | 2013-02-27 | 南京中医药大学 | Rhizoma cyperi four-drug decoction transdermal patch and preparation method thereof |
| CN104306563A (en) * | 2014-09-27 | 2015-01-28 | 李保集 | A medicine for treating primary sciatica and a preparing method thereof |
| CN105056116A (en) * | 2015-08-05 | 2015-11-18 | 肖庆义 | Traditional Chinese medicine composition for treating lumbar disc protrusion and preparation method thereof |
| CN105560610A (en) * | 2016-01-25 | 2016-05-11 | 彭效民 | Traditional Chinese medicine for treating bone fracture and preparation method |
| CN107281444A (en) * | 2017-06-23 | 2017-10-24 | 南充市中医医院 | A kind of pharmaceutical composition of analgesic and its production and use |
| CN107281444B (en) * | 2017-06-23 | 2021-03-02 | 南充市中医医院 | Analgesic pharmaceutical composition and preparation method and application thereof |
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