CN101850058B - Chinese medicament for preventing and treating agrypnia, memory loss and alzheimers disease and method - Google Patents

Chinese medicament for preventing and treating agrypnia, memory loss and alzheimers disease and method Download PDF

Info

Publication number
CN101850058B
CN101850058B CN2010101802016A CN201010180201A CN101850058B CN 101850058 B CN101850058 B CN 101850058B CN 2010101802016 A CN2010101802016 A CN 2010101802016A CN 201010180201 A CN201010180201 A CN 201010180201A CN 101850058 B CN101850058 B CN 101850058B
Authority
CN
China
Prior art keywords
grams
radix
raw materials
insomnia
fine powder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2010101802016A
Other languages
Chinese (zh)
Other versions
CN101850058A (en
Inventor
颜色清
许燕妮
郑胜荣
林丽斌
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GUANGDONG YIHE PHARMACEUTICAL CO Ltd
Original Assignee
GUANGDONG YIHE PHARMACEUTICAL CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GUANGDONG YIHE PHARMACEUTICAL CO Ltd filed Critical GUANGDONG YIHE PHARMACEUTICAL CO Ltd
Priority to CN2010101802016A priority Critical patent/CN101850058B/en
Publication of CN101850058A publication Critical patent/CN101850058A/en
Application granted granted Critical
Publication of CN101850058B publication Critical patent/CN101850058B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a Chinese medicament for preventing and treating agrypnia, memory loss and alzheimers disease, which is prepared from the following components: 10 to 20 grams of sun-dried ginseng, 30 to 40 grams of spina data seed, 20 to 30 grams of shizandra berry, 20 to 30 grams of szechuan lovage rhizome, 30 to 40 grams of dwarf lilyturf tuber, 20 to 30 grams of thinleaf milkwort root-bark, 40 to 50 grams of root poria, 40 to 50 grams of grassleaf sweelflag rhizome, 40 to 50 grams of white paeony root, 40 to 50 grams of prepared rehmannia root, 10 to 20 grams of liquoric root, 20 to 30 grams of platycladi seed, 50 to 60 grams of oyster shell, 30 to 40 grams of silktree albizzia bark, 40 to 50 grams of dragon bone, 40 to 50 grams of tortoise plastron and 40 to 50 grams of radix astragali. The Chinese medicament is prepared by the following steps of: weighing the Chinese medicinal raw materials in proportion, drying the raw materials, partially grinding the raw materials into powder and then performing alcohol extraction, water extraction, concentration, combination, stirring, drying and uniform mixing. The Chinese medicament adopts natural Chinese medicinal herbs as the raw materials, and has the characteristics of innocuity to human bodies, no side effect, no need of decoction, convenient treatment and carrying, and effective rate of over 93 percent.

Description

The Chinese medicine and the method for a kind of prevention and Cure for insomnia, forgetful, senile dementia
Technical field
The present invention relates to a kind of Chinese medicine preparation, relate in particular to the Chinese medicine and the method for a kind of Cure for insomnia, forgetful senile dementia, belong to technical field of Chinese medicines.
Background technology
Sleep is that body restores, integrates and consolidate the important step of memory as the necessary process of life, is able-bodied important leverage.Say that in a sense sleep is more precious, more important than food.
In recent years, the people who suffers from insomnia forgetfulness disease increases day by day, and the method for reply insomnia forgetfulness disease then lacks relatively.In order to give oneself ideal sleep and good memory; People have also paid close attention to the diet and the healthy lifestyles of science gradually; But with the quickening pace of modern life, the increase of life stress, and the forming of night life, bad life habits such as drink causes much human that sleep disorder has just been arranged unconsciously; Insomnia, forgetful situation occur, had a strong impact on quality of life and physical and mental health.
Sleep disorder is the modal performance of insomnia; Cardinal symptom for do not have enough sleep, difficulty falling asleep, early awakening, dreaminess; And to the existing influence of hotlist on daytime; For example feel fatigue, irritated, lose one's temper, absent minded and poor memory etc., insomniac's learning capacity and work efficiency are significantly reduced, also be prone to cause the generation of other sudden hurt accidents and the generation of various diseases.
Amnesia medically is being called " temporary dysmnesia ", is amnemonic a kind of, is because the hypomnesis that blood supply in brain is not enough, the cerebral nerve reflection function lowly causes, forgetful a kind of disease when anything crops up.Memory is existing cause effect relation with sleep aspect certain: the people is under sleep state, and the brain oxygen-supplying amount increases relatively, helps the enhancing of memory function; Competent sleep can make the people resourceful, and learning capacity improves.So good sleep can make amnesia obtain very big improvement, but with the quickening pace of modern life, the much human sleep state is bad now, has just suffered from insomnia forgetfulness disease at leisure, unconsciously.Insomnia forgetfulness disease has become one of present epidemic disease, though unlike disease entail dangers to life such as diabetes, hypertension, bring serious harmful effect also can for people's life.Therefore, pay close attention to, be familiar with, improve insomnia forgetfulness disease and can not be ignored, need to be resolved hurrily.
So-called senile dementia; Claim again Alzheimer (Alzheimer ' s disease; AD) be a kind of PDCD that occurs in geratic period and presenium; It shows as persistence higher nerve functional activity obstacle, is not having aspect obstacles such as the judgement of memory thinking analysis, visual space identification, emotion under the state of disturbance of consciousness.Its characteristic pathological change is the cerebral cortex atrophy, and with amyloid-beta (β-amyloid, β-AP) deposit; Neurofibrillary tangles (neurofibrillary tangles, NFT), mass memory property neuron number reduces; And senile plaque (senileplaque, formation SP).It shows as amnesia at first, engenders dystropy, finally loses viability.
Senile dementia brings heavy financial burden not only for society and patient family, and patient's relatives are also caused immense pressure in life and the misery on the soul.At present, China more than 60 years old aging population be about 1.5 hundred million, account for total population about 10%.According to statistics, China's care of patients with senile dementia has surpassed 5,000,000 people, rank first in the world, but the prescription on individual diagnosis rate is merely 22.8%, less than developed country half, has become after cardiovascular and cerebrovascular disease and malignant tumor, threatens the third-largest killer of human health.If the mankind can not find effective medicine and Therapeutic Method, the whole world estimates have 100,000,000 people to suffer from senile dementia after 50 years, and senile dementia will become the epidemic diseases of human society.
Summary of the invention
The purpose of this invention is to provide safer, effective novel drugs and Therapeutic Method such as a kind of prevention and Cure for insomnia, forgetful, vertigo and tinnitus, senile dementia, will bring more Gospel for the patient.
In order to address the above problem, the technical scheme that the present invention adopted is:
A kind of treatment senile dementia; The collection benefiting QI and nourishing blood; Kidney calming; In the Chinese medicine of one, it is processed by following Chinese medicine raw materials by weight proportion the merit
Figure DEST_PATH_GSB00000764163200021
of Fructus Alpiniae Oxyphyllae of calming the nerves.
Figure DEST_PATH_GSB00000764163200022
Another object of the present invention provides the method for the Chinese medicine that is used to prepare above-mentioned prevention and Cure for insomnia, forgetful, senile dementia, comprises the steps:
(1) getting Radix Ginseng 5~10g, the Radix Paeoniae Alba 20~25g and Poria cum Radix Pini 20~25g powder becomes fine powder subsequent use;
(2) take by weighing Radix Ginseng 5~10g, Semen Ziziphi Spinosae 30~40g, Fructus Schisandrae Chinensis 20~30g, Rhizoma Chuanxiong 20~30g, Radix Ophiopogonis 30~40g, Radix Polygalae 20~30g, Poria cum Radix Pini 20~25g, Rhizoma Acori Graminei 40~50g, the Radix Paeoniae Alba 20~25g, Radix Rehmanniae Preparata 40~50g, Radix Glycyrrhizae 10~20g, Semen Platycladi 20~30g, Concha Ostreae 50~60g, Cortex Albiziae 30~40g, Os Draconis 40~50g, Carapax et Plastrum Testudinis 40~50g and the Radix Astragali 40~50g; Ethanol extraction with 70~80% 2 times; Merge extracted twice liquid; And recovery ethanol, it is that 1.10~1.30 thick paste is subsequent use that extracting solution is concentrated into relative density;
(3) the filtering residue water of step (2) being crossed with ethanol extraction decocts 2 times, merges decocting liquid twice, and decocting liquid is concentrated into relative density is 1.20~1.25 thick paste; Add the fine powder of step (1) preparation and the thick paste of step (2) preparation, mixing, oven dry; Powder becomes fine powder again; Then fine powder is granulated drying, mixing.
The present invention has following advantage:
1, the present invention selects for use natural Chinese medicinal herb to be raw material, and is harmless to human non-toxic, has no side effect.
2, the present invention need not decoct, and treats easy to carryly, and effective percentage reaches more than 93%.
3, prescription of the present invention meets theory of Chinese medical science, and the traditional Chinese medical science thinks, the people is prone to insomnia, forgetful, senile dementia, is with insufficiency of vital energy and blood, due to the disarmony between the heart and kidney.Forgetful and dull-witted its sick position is at brain, main sick at kidney, and is closely related with liver, spleen.Prevention and Cure for insomnia, forgetful, senile dementia should be nourished blood with benefit, kidney calming, and the Fructus Alpiniae Oxyphyllae of calming the nerves, accent reach to seek to defend and are the rule of treatment.Therefore, obey the present invention for a long time and can make us making light of one's life by commiting suicide not old, the sliding pool of human body is fair and clear, energetic, safeguards the intravital ecological balance of people, reaches the purpose of disease-relieving and physique enhancing.
Compare with prior art, the present invention adopts Chinese herbal medicine as raw material, and is with low cost, and curative effect is fast, and persistent has no side effect.
The traditional Chinese medical science thinks, the people is prone to insomnia, forgetful, senile dementia, is because of due to insufficiency of vital energy and blood, the disarmony between the heart and kidney.And think forgetful and dull-witted its disease at brain, and main sick at kidney, closely related with liver, spleen.The Chinese medicine mechanism that the present invention treats above disease is:
The function of Radix Ginseng cures mainly: sweet, little hardship, flat, return spleen, lung, heart channel.Strongly invigorating primordial QI, QI invigorating and blood producing helps intensive culture refreshing, happy Fructus Alpiniae Oxyphyllae.Radix Ginseng has the effects such as immunity, nervous system regulation and excited hemopoietic system function of good defying age, resisting fatigue, raising human body; Can improve the microcirculation of middle-aged and elderly people; Improve memory, learning capacity; Be usually used in treating all types of senile dementias, be particularly useful for heart spleen qi-blood deficiency syndrome, and benefit is arranged and not dry effect with Radix Ginseng.
The function of Semen Ziziphi Spinosae cures mainly: sweet, sour, flat, return liver, gallbladder, heart channel.Tonifying liver, mind calming, arresting sweating, promote the production of body fluid.Be used for restlessness of asrhenia type and insomnia, palpitation with fear dreaminess, have sedative-hypnotic effect.
The function of Fructus Schisandrae Chinensis cures mainly: sour, sweet, warm, return lung, heart kidney channel.Have that convergence is astringent or styptic treatment for spontaneous sweating, benefit institute promotes the production of body fluid, kidney calming.Be used for palpitation and insomnia, and Fructus Schisandrae Chinensis contains the antioxidant composition, can be active with the SOD in its hetero-organization through improving blood, strengthen the human body oxidation resistance, reach the defying age purpose.
The function of Rhizoma Chuanxiong cures mainly: hot, warm.Return liver, gallbladder, pericardium channel.Blood-activating and qi-promoting, the up head, following regulating menstruation water, middle relieving stagnation, its active ingredient ligustrazine and Chen Wei acid have certain calmness, inhibitory action to the central nervous system.The also expansible cerebrovascular of Rhizoma Chuanxiong improves the vascular perfusion of brain, the formation of anticoagulant and thrombosis; Externally peripheral vessels has direct dilating effect; Can bring high blood pressure down enduringly, be usually used in treating various types of senile dementias, the person is especially suitable to qi depression to blood stasis, retardance brain network.
The function of Radix Ophiopogonis cures mainly: sweet, little hardship, be slightly cold GUIXIN, lung, stomach warp.Still effectively nourish analeptic Radix Ophiopogonis, but clearing lung and nourishing yin, reinforcing stomach reg fluid, relieving restlessness mind calming, Fructus Alpiniae Oxyphyllae tonify deficiency.Be usually used in treating senile dementia, it is thirsty to have dry tongue concurrently, irritability, and cough caused by dryness expectorant is glutinous, the dryness of the intestine constipation, memory is degradation disease down.
The function of Radix Polygalae cures mainly: bitter, hot, warm, and GUIXIN, kidney, lung meridian.The wholwe-hearted kidney of its merit, so but the relieving palpitation spasmolytic, the peace that exorcises evil spirits dream, strong will benefit is smart, control forgetful, suitable treatment senile dementia turbid phlegm blocking the clear orifices disease.
Poria cum Radix Pini's function cures mainly: sweet, light, flat.GUIXIN, spleen channel.Have mind calming, the sharp scorching effect of calming the nerves.Governance guilty fright, forgetfulness, insomnia, panic moan with pain, difficult urination.Its benefit warm in nature, drugs with tonic function being used for the debility.For mental derangement, labor is timid forgetful, the suitable replenishing vital QI with drugs of warm nature mind.
The function of Rhizoma Acori Graminei cures mainly: hot, bitter, warm, and GUIXIN, stomach warp.The removing dampness appetizing, the eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae, removing dampness appetizing.Cure mainly the coma epilepsy, forgetful insomnia, Hiccough and deaf; The gastral cavity painful abdominal mass is not hungry etc., and effects such as the memory ability of improvement, blood vessel dilating, blood pressure lowering are arranged, and its effective ingredient α-asaricin has antiepileptic action; Be usually used in treating senile dementia, to close brain network disease especially suitable in turbid resistance to expectorant.
The function of the Radix Paeoniae Alba cures mainly: bitter, acid is slightly cold.Return liver, spleen channel.Has the suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, yin fluid astringing, hidroschesis effect.Control dizzy, the hypochondriac pain of headache, stomachache, limb pain twin, blood deficiency and yellow complexion, spontaneous perspiration, night sweat etc.
The function of Radix Rehmanniae Preparata cures mainly: its tepor.Return liver, kidney channel.Have nourishing YIN and supplementing blood, the smart town of benefit marrow effect.Be used for liver, deficiency of the kidney yin, soreness of the waist and knees, interior steaming hectic fever, the night sweat seminal emission, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, dizzy, tinnitus, early whitening of beard and hair, insomnia and dreamful sleep etc.
The function of Concha Ostreae cures mainly: salty, be slightly cold.Return liver, gallbladder, kidney channel.Tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving.Be used for the palpitation with fear insomnia, vertigo and tinnitus, scrofula sucutaneous nodule , mass in the abdomen mass in the abdomen.The Concha Ostreae (calcined) convergence is astringent or styptic treatment for spontaneous sweating.Be used for spontaneous sweating, emission and spermatorrhea, bleeding not during menses, stomachache acid regurgitation.
The function of Semen Platycladi cures mainly: sweet, flat.GUIXIN, kidney, large intestine channel.Tranquilizing by nourishing the heart, loosening bowel to relieve constipation, hidroschesis.Be used for deficiency of YIN-blood, fidgets due to deficiency insomnia, severe palpitation, dryness of the intestine constipation, night sweat due to yin deficiency.
The function of Cortex Albiziae cures mainly: sweet, flat.GUIXIN, liver, lung meridian.Resolving stagnation for tranquilization, promoting blood circulation and detumescence.Be used for irritability, melancholy insomnia.
The function of Carapax Et Plastrum Testudinis cures mainly: salty, sweet, be slightly cold.Return liver, kidney, heart channel.Nourishing YIN for suppressing the hyperactive YANG, kidney tonifying bone strengthening, the reinforcing the heart of nourishing blood.Be used for hectic fever due to deficiency of YIN, hectic fever due to YIN-deficiency night sweat is had a dizzy spell, and the muscles and bones flaccidity is soft, and it is forgetful to have a guilty conscience.
The function of Os Draconis cures mainly: sweet, puckery, flat.GUIXIN, liver, kidney, large intestine channel.Tranquillizing the mind by relieving convulsion, the arresting sweating controlling nocturnal emission with astringent drugs; Be used for palpitation and being susceptible to fright, insomnia and dreamful sleep, spontaneous sweating.
The function of the Radix Astragali cures mainly: sweet, and temperature.Return lung, spleen channel.Tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema promotes the production of body fluid and nourishes blood, the stagnant blood stasis dispelling of row, expelling pus and toxin by strengthening QI, expelling pus and promoting granulation.It is weak to be used for the deficiency of vital energy, anorexia and loose stool, and sinking of QI of middle-JIAO, the chronic diarrhea proctoptosis, the exterior deficiency spontaneous perspiration, deficiency of vital energy edema, interior-heat is quenched one's thirst, the blood deficiency dull yellowish colored skin, hemiplegia, arthralgia pain Chinese medicine research in numb modern age can also be treated senile dementia.
The function of Radix Glycyrrhizae cures mainly: sweet, flat.GUIXIN, lung, spleen, stomach warp.It has invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Cure mainly the anxious pain of weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, extremity contraction, cushion toxicity, strong etc.
The specific embodiment
Through embodiment the present invention is explained further details below, these embodiment only are used for explaining the present invention, do not limit the scope of the invention.
Embodiment 1
A kind of treatment senile dementia, the collection benefiting QI and nourishing blood, kidney calming, the power amplifier of the Fructus Alpiniae Oxyphyllae of calming the nerves is in the Chinese medicine of one, and it is processed by following Chinese medicine raw materials by weight proportion.
Figure DEST_PATH_GSB00000764163200011
Embodiment 2
A kind of treatment senile dementia; The collection benefiting QI and nourishing blood; Kidney calming; In the Chinese medicine of one, it is processed by following Chinese medicine raw materials by weight proportion the merit of Fructus Alpiniae Oxyphyllae of calming the nerves.
Figure DEST_PATH_GSB00000764163200013
Embodiment 3
A kind of treatment senile dementia; The collection benefiting QI and nourishing blood; Kidney calming; In the Chinese medicine of one, it is processed by following Chinese medicine raw materials by weight proportion the merit of Fructus Alpiniae Oxyphyllae of calming the nerves.
Figure DEST_PATH_GSB00000764163200015
Embodiment 4
(1) getting Radix Ginseng 5g, Radix Paeoniae Alba 25g and Poria cum Radix Pini 25g powder becomes fine powder subsequent use;
(2) take by weighing Radix Ginseng 5g, Semen Ziziphi Spinosae 40g, Fructus Schisandrae Chinensis 30g, Rhizoma Chuanxiong 30g, Radix Ophiopogonis 40g, Radix Polygalae 30g, Poria cum Radix Pini 25g, Rhizoma Acori Graminei 50g, Radix Paeoniae Alba 25g, Radix Rehmanniae Preparata 50g, Radix Glycyrrhizae 20g, Semen Platycladi 30g, Concha Ostreae 60g, Cortex Albiziae 40g, Os Draconis 50g, Carapax et Plastrum Testudinis 50g and Radix Astragali 50g; Ethanol extraction with 70~80% 2 times; Merge extracted twice liquid; And recovery ethanol, it is that 1.10 thick paste is subsequent use that extracting solution is concentrated into relative density;
(3) the filtering residue water of step (2) being crossed with ethanol extraction decocts 2 times, merges decocting liquid twice, and decocting liquid is concentrated into relative density is 1.20 thick paste, the thick paste that the fine powder that adds step (1) preparation and step (2) prepare; Mixing, oven dry, powder becomes fine powder again; Then fine powder is granulated drying, mixing.
Embodiment 5
(1) getting Radix Ginseng 10g, Radix Paeoniae Alba 20g and Poria cum Radix Pini 20g powder becomes fine powder subsequent use;
(2) take by weighing Radix Ginseng 10g, Semen Ziziphi Spinosae 30g, Fructus Schisandrae Chinensis 20g, Rhizoma Chuanxiong 20g, Radix Ophiopogonis 30g, Radix Polygalae 20g, Poria cum Radix Pini 20g, Rhizoma Acori Graminei 40g, Radix Paeoniae Alba 20g, Radix Rehmanniae Preparata 40g, Radix Glycyrrhizae 10g, Semen Platycladi 20g, Concha Ostreae 50g, Cortex Albiziae 30g, Os Draconis 40g, Carapax et Plastrum Testudinis 40g and Radix Astragali 40g; Ethanol extraction with 70~80% 2 times; Merge extracted twice liquid; And recovery ethanol, it is that 1.30 thick paste is subsequent use that extracting solution is concentrated into relative density;
(3) the filtering residue water of step (2) being crossed with ethanol extraction decocts 2 times, merges decocting liquid twice, and decocting liquid is concentrated into relative density is 1.25 thick paste, the thick paste that the fine powder that adds step (1) preparation and step (2) prepare; Mixing, oven dry, powder becomes fine powder again; Then fine powder is granulated drying, mixing.
Embodiment 6
(1) getting Radix Ginseng 8g, Radix Paeoniae Alba 23g and Poria cum Radix Pini 22g powder becomes fine powder subsequent use;
(2) take by weighing Radix Ginseng 8g, Semen Ziziphi Spinosae 35g, Fructus Schisandrae Chinensis 25g, Rhizoma Chuanxiong 25g, Radix Ophiopogonis 35g, Radix Polygalae 25g, Poria cum Radix Pini 23g, Rhizoma Acori Graminei 45g, Radix Paeoniae Alba 22g, Radix Rehmanniae Preparata 45g, Radix Glycyrrhizae 15g, Semen Platycladi 25g, Concha Ostreae 55g, Cortex Albiziae 35g, Os Draconis 45g, Carapax et Plastrum Testudinis 45g and Radix Astragali 45g; Ethanol extraction with 70~80% 2 times; Merge extracted twice liquid; And recovery ethanol, it is that 1.20 thick paste is subsequent use that extracting solution is concentrated into relative density;
(3) the filtering residue water of step (2) being crossed with ethanol extraction decocts 2 times, merges decocting liquid twice, and decocting liquid is concentrated into relative density is 1.25 thick paste, the thick paste that the fine powder that adds step (1) preparation and step (2) prepare; Mixing, oven dry, powder becomes fine powder again; Then fine powder is granulated drying, mixing.
Embodiment 7
In order to prove this Chinese patent medicine pharmacological effect, carried out contrast test mice and rat.
1, sedation: irritate stomach with said preparation, can obviously reduce the spontaneous activity in mice number of times, prolong pentobarbital sodium induced mice length of one's sleep.
2, improve memory effect (strengthening the ability of learning and memory effect): can improve the memory of scopolamine induced mice memory acquisition disturbance and sodium nitrite induced mice and consolidate obstacle.
3, dementia effect: can reduce alzheimer disease rat swimming labyrinth required time due to the amyloid-beta matter, reduce swimming labyrinth errors number, rising rat cerebral tissue is from the activity of the binding capacity and the Acetylcholinesterase of receptor.
Embodiment 8
In order to show therapeutic effect of the present invention, as follows with the clinical efficacy situation statistics of diseases such as various forgetful, the insomnias of Chinese patent drugs for treatment 100 examples of the present invention, senile dementia:
One, case is selected
Two, Therapeutic Method
Patient for insomnia, forgetful, senile dementia gives Chinese patent medicine of the present invention and takes, severe patient every day 3 times, each 2~4; The lighter every day 2 times, each 1~2 insomnia, was a course of treatment in forgetful per 30 days, serve on 2 courses of treatment.Dementia patient serve on 3~4 courses of treatment.
Three, treatment standard
Produce effects: clinical symptom disappearance, functional rehabilitation is normal, drug withdrawal more than 1 year insomniac person normally sleeping, forgetful recovery is normal, senile dementia person disease is not seen and is increased the weight of.
Effectively: clinical symptom relief, stable disease is observed person more than month.
Invalid: clinical symptoms does not have obvious improvement.
Four, curative effect statistics
Disease Case load Produce effects Effectively Invalid Effective percentage (%)
Insomnia 30 18 11 1 96.7
Improve memory, strengthen the ability of learning and memory effect 35 19 14 2 94.3
Senile dementia 30 7 20 3 93.3
Visible by above-mentioned clinical data, Chinese patent medicine of the present invention all has better curative effect to various types of insomnias, forgetful, dementia.
Case one: Lee * *, the woman, 48 years old, because work family pressure is big, normal insomnia leaned on sleeping pill to fall asleep, often vertigo and tinnitus, dreaminess, hyperhidrosis.Introduce through kith and kin, take Chinese medicine preparation of the present invention and take effect after 1 week, sleeping naturally after continuing to take medicine one month, above transference cure.
Case two: the man, 52 years old, since the tense working environment, the palpitation with fear that occurs having a guilty conscience, dysuria, mental derangement, the muscles and bones flaccidity is soft.After Chinese medicine preparation one wheat harvesting period of the present invention is taken in friend's introduction, all transference cures, at present, energetic, health is ditto become quite a different person.
Case three: the woman, 76 years old, senile dementia, disease sees that dry tongue is thirsty, irritability, the dryness of the intestine constipation, cough caused by dryness expectorant is glutinous, and it is dizzy to have a headache, early whitening of beard and hair, spontaneous sweating, melancholy insomnia.Once treatment in hospital, the situation commentaries on classics of not getting better.Take Chinese medicine preparation of the present invention after three months through kith and kin's introduction, various diseases disappear basically, adhere to taking medicine and have a surplus in 1 year, and are healthy, good.
In sum, our compatibility is rigorous, treating both the principal and secondary aspects of a disease, and the collection benefiting QI and nourishing blood, kidney calming, the effect of the Fructus Alpiniae Oxyphyllae of calming the nerves can make QI movement being in harmonious way in one, the traffic of heart kidney, QI and blood is full.To because of insufficiency of vital energy and blood, disarmony between the heart and kidney, the dysphoria that qi depression to blood stasis causes, insomnia and dreamful sleep, palpitation and amnesia, absentminded, vertigo and tinnitus, early whitening of beard and hair, diseases such as senile dementia are that the medicine card is congenial, it is special to imitate work power.Especially we are after being refined into capsule with the modern science and technology extraction, and curative effect is more remarkable.

Claims (2)

1. the Chinese medicine of prevention and Cure for insomnia, forgetful, senile dementia, it is characterized in that: it is to be processed by following Chinese medicine raw materials by weight proportion:
Radix Ginseng 10~20g, Semen Ziziphi Spinosae 30~40g, Fructus Schisandrae Chinensis 20~30g, Rhizoma Chuanxiong 20~30g; Radix Ophiopogonis 30~40g, Radix Polygalae 20~30g, Poria cum Radix Pini 40~50g, Rhizoma Acori Graminei 40~50g; The Radix Paeoniae Alba 40~50g, Radix Rehmanniae Preparata 40~50g, Radix Glycyrrhizae 10~20g, Semen Platycladi 20~30g; Concha Ostreae 50~60g, Cortex Albiziae 30~40g, Os Draconis 40~50g, Carapax et Plastrum Testudinis 40~50g and the Radix Astragali 40~50g.
2. a method that is used to prepare the Chinese medicine of the described prevention of claim 1 and Cure for insomnia, forgetful, senile dementia is characterized in that: comprise the steps:
(1) getting Radix Ginseng 5~10g, the Radix Paeoniae Alba 20~25g and Poria cum Radix Pini 20~25g powder becomes fine powder subsequent use;
(2) take by weighing Radix Ginseng 5~10g, Semen Ziziphi Spinosae 30~40g, Fructus Schisandrae Chinensis 20~30g, Rhizoma Chuanxiong 20~30g, Radix Ophiopogonis 30~40g, Radix Polygalae 20~30g, Poria cum Radix Pini 20~25g, Rhizoma Acori Graminei 40~50g, the Radix Paeoniae Alba 20~25g, Radix Rehmanniae Preparata 40~50g, Radix Glycyrrhizae 10~20g, Semen Platycladi 20~30g, Concha Ostreae 50~60g, Cortex Albiziae 30~40g, Os Draconis 40~50g, Carapax et Plastrum Testudinis 40~50g and the Radix Astragali 40~50g; Ethanol extraction with 70~80% 2 times; Merge extracted twice liquid; And recovery ethanol, it is that 1.10~1.30 thick paste is subsequent use that extracting solution is concentrated into relative density;
(3) the filtering residue water of step (2) being crossed with ethanol extraction decocts 2 times, merges decocting liquid twice, and decocting liquid is concentrated into relative density is 1.20~1.25 thick paste; Add the fine powder of step (1) preparation and the thick paste of step (2) preparation, mixing, oven dry; Powder becomes fine powder again; Then fine powder is granulated drying, mixing.
CN2010101802016A 2010-05-17 2010-05-17 Chinese medicament for preventing and treating agrypnia, memory loss and alzheimers disease and method Expired - Fee Related CN101850058B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2010101802016A CN101850058B (en) 2010-05-17 2010-05-17 Chinese medicament for preventing and treating agrypnia, memory loss and alzheimers disease and method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2010101802016A CN101850058B (en) 2010-05-17 2010-05-17 Chinese medicament for preventing and treating agrypnia, memory loss and alzheimers disease and method

Publications (2)

Publication Number Publication Date
CN101850058A CN101850058A (en) 2010-10-06
CN101850058B true CN101850058B (en) 2012-08-15

Family

ID=42801848

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2010101802016A Expired - Fee Related CN101850058B (en) 2010-05-17 2010-05-17 Chinese medicament for preventing and treating agrypnia, memory loss and alzheimers disease and method

Country Status (1)

Country Link
CN (1) CN101850058B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103007146B (en) * 2012-03-29 2014-12-31 叶国生 Healthcare nutrition powder for enhancing memory ability
CN102669659A (en) * 2012-04-27 2012-09-19 无限极(中国)有限公司 Health-care food with sleep improving function
CN102784357B (en) * 2012-08-01 2013-09-04 许凤华 Method for preparing traditional Chinese medicine for treating insomnia caused by addiction to strong tea
CN103041157B (en) * 2013-01-22 2014-12-17 赵永红 Brain-strengthening and intelligence-promoting pills and preparation method thereof
CN103721038A (en) * 2013-11-25 2014-04-16 青岛盛嘉信息科技有限公司 Traditional Chinese medicine composition for preventing and treating insomnia and amnesia
CN103933330A (en) * 2014-03-31 2014-07-23 李友军 Insomnia-resistant traditional Chinese medicine composition
CN104189358A (en) * 2014-08-19 2014-12-10 李新民 Formula for treating senile dementia
CN104825836A (en) * 2015-04-28 2015-08-12 广西大学 Traditional Chinese medicine preparation for treating senile dementia
CN105168792A (en) * 2015-10-27 2015-12-23 刘斌 Brain-boosting nerve-soothing medicine
CN105687697A (en) * 2016-02-05 2016-06-22 韩俊峰 Compound traditional Chinese medicine decoction for treating insomnia and depression
CN106177046A (en) * 2016-08-29 2016-12-07 杨添福 A kind of nervus cognition disorder medicine based on the exploitation of Pu Lining potassium and preparation method thereof
CN108295165A (en) * 2018-03-27 2018-07-20 贵州康珠药业有限公司 It is a kind of to be used to improve plaster, plaster of memory and preparation method thereof
CN112076296A (en) * 2020-09-11 2020-12-15 辽宁中医药大学附属医院 Foot bath medicine composition for treating senile insomnia and preparation method thereof
CN113599438A (en) * 2021-09-07 2021-11-05 黑龙江省济仁药业有限公司 Traditional Chinese medicine composition for treating children amnesia and preparation method and application thereof
CN114848678B (en) * 2022-04-29 2023-07-07 广州中医药大学第一附属医院 Application of tortoise plastron in preparing medicine for treating cerebral senility
CN116392569A (en) * 2023-04-17 2023-07-07 天津市武清区爱康中医医院 Traditional Chinese medicine preparation for enhancing memory and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1698671A (en) * 2004-05-21 2005-11-23 吴占亨 Oral liquid for replenishing the heart and soothing the nerves
CN101130007A (en) * 2007-09-14 2008-02-27 尹克华 Traditional Chinese medicine for treating neurasthenia aypnia
CN101653553A (en) * 2009-08-10 2010-02-24 黄山 Particle for benefiting the heart and calming nerves

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1698671A (en) * 2004-05-21 2005-11-23 吴占亨 Oral liquid for replenishing the heart and soothing the nerves
CN101130007A (en) * 2007-09-14 2008-02-27 尹克华 Traditional Chinese medicine for treating neurasthenia aypnia
CN101653553A (en) * 2009-08-10 2010-02-24 黄山 Particle for benefiting the heart and calming nerves

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘占国等.方到病除:独特秘方治病绝招.《方到病除:独特秘方治病绝招》.中国医药科技出版社,1998,(第2版),第102-103页. *
李增强.古今中外名人养生秘诀录.《古今中外名人养生秘诀录》.广西民族出版社,1996,(第1版),第137页. *

Also Published As

Publication number Publication date
CN101850058A (en) 2010-10-06

Similar Documents

Publication Publication Date Title
CN101850058B (en) Chinese medicament for preventing and treating agrypnia, memory loss and alzheimers disease and method
CN102078520B (en) Chinese medicinal preparation for treating nervous headache and preparation method thereof
CN104435775A (en) Chinese medicinal health-care spirit and preparation method thereof
CN103041264B (en) Kudzuvine root brain-boosting and intelligence-boosting oral solution with function of preventing vascular dementia and preparation method thereof
CN103520621B (en) A kind of Chinese medicine composition for the treatment of senile cataract and preparation method thereof
CN103083505A (en) Liver-soothing and qi-regulating traditional Chinese medicine composition used for treating depression, and preparation method thereof
CN102335330A (en) Traditional Chinese medicine composition for treating insomnia
CN104940740A (en) Traditional Chinese medicine composition for treating polycystic ovarian syndrome and preparation method thereof
CN103127472A (en) Traditional Chinese medicine compound for refractory insomnia
CN105999113B (en) A kind of Chinese medicine composition and preparation method thereof for treating intractable aypnia
CN104107309A (en) Kidney-tonifying healthy soup
CN104173957A (en) Anti-senile life-prolonging plaster
CN101195003B (en) Proprietary Chinese medicine for treating apoplexy and sequela
CN104524479B (en) A kind of Chinese medicine composition for treating premenstrual syndrome and preparation method thereof
CN104042981A (en) Medicament for treating postnatal constipation and preparation method thereof
CN203252935U (en) Anti-senile and life-prolonging plaster
CN105232999A (en) Traditional Chinese medicine composition for tonifying qi, activating blood and controlling nocturnal emission
CN104940613A (en) Traditional Chinese medicine pills for treating vestibular neuritis and preparation method
CN104758534A (en) Medicine for treating osteoporosis and preparing method thereof
CN102793826B (en) Traditional Chinese medicine for treating hypertension early-stage kidney damage and preparation method thereof
CN100400090C (en) Medicine composition for treating myasthenia gravis and prepn. method therefor
CN104383450B (en) It is a kind of to treat the dark yellow traditional Chinese medicine pill of skin
CN104825846A (en) Traditional Chinese medicinal composition for treating facial neuritis
CN104069402A (en) Traditional Chinese medicine composition for treating alopecia and poliosis as well as preparation method and application thereof
CN104223062A (en) Health cortex lycii oral solution with blood pressure and blood sugar reducing effects and preparation method of health cortex lycii oral solution

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20120815

Termination date: 20150517

EXPY Termination of patent right or utility model