CN101848909A - 可用作蛋白激酶抑制剂的吡咯并[3,2-c]吡啶 - Google Patents
可用作蛋白激酶抑制剂的吡咯并[3,2-c]吡啶 Download PDFInfo
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| PCT/US2007/003767 WO2007095223A2 (en) | 2006-02-14 | 2007-02-12 | Pyrrolo(3,2-c) pyridines useful as inhibitors of protein kinases |
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| CN101848909A true CN101848909A (zh) | 2010-09-29 |
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| JP (1) | JP2009528991A (enExample) |
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| WO (1) | WO2007095223A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109071455A (zh) * | 2016-03-11 | 2018-12-21 | 科尔沃斯制药股份有限公司 | 用于调节布鲁顿酪氨酸激酶的化合物及方法 |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1831225A2 (en) | 2004-11-19 | 2007-09-12 | The Regents of the University of California | Anti-inflammatory pyrazolopyrimidines |
| CN102532134A (zh) | 2006-01-17 | 2012-07-04 | 沃泰克斯药物股份有限公司 | 适用作詹纳斯激酶抑制剂的吖吲哚类 |
| KR20090017498A (ko) | 2006-04-04 | 2009-02-18 | 더 리젠트스 오브 더 유니이버시티 오브 캘리포니아 | Pi3 키나제 길항물질 |
| EP2124951B1 (en) | 2006-12-21 | 2014-05-21 | Vertex Pharmaceuticals Inc. | 5-cyan0-4- (pyrrolo[2, 3b]pyridine-3-yl) -pyrimidine derivatives useful as protein kinase inhibitors |
| WO2009046448A1 (en) | 2007-10-04 | 2009-04-09 | Intellikine, Inc. | Chemical entities and therapeutic uses thereof |
| WO2009145814A2 (en) * | 2008-03-10 | 2009-12-03 | Vertex Pharmaceuticals Incorporated | Pyrimidines and pyridines useful as inhibitors of protein kinases |
| EP2252293B1 (en) * | 2008-03-14 | 2018-06-27 | Intellikine, LLC | Kinase inhibitors and methods of use |
| US8993580B2 (en) | 2008-03-14 | 2015-03-31 | Intellikine Llc | Benzothiazole kinase inhibitors and methods of use |
| US20110224223A1 (en) | 2008-07-08 | 2011-09-15 | The Regents Of The University Of California, A California Corporation | MTOR Modulators and Uses Thereof |
| BRPI0915231A2 (pt) | 2008-07-08 | 2018-06-12 | Intellikine Inc | compostos inibidores de quinase e métodos de uso |
| KR101903354B1 (ko) | 2009-06-17 | 2018-10-04 | 버텍스 파마슈티칼스 인코포레이티드 | 인플루엔자 바이러스 복제의 억제제 |
| WO2011047384A2 (en) | 2009-10-16 | 2011-04-21 | The Regents Of The University Of California | Methods of inhibiting ire1 |
| KR101173678B1 (ko) | 2010-10-20 | 2012-08-13 | 한국과학기술연구원 | 피롤로[3,2-c]피리딘 유도체 및 그의 제조 방법 |
| EP2651940A1 (en) | 2010-12-16 | 2013-10-23 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
| UA118010C2 (uk) | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
| WO2013077921A2 (en) | 2011-09-02 | 2013-05-30 | The Regents Of The University Of California | Substituted pyrazolo[3,4-d]pyrimidines and uses thereof |
| KR20150061651A (ko) | 2012-09-26 | 2015-06-04 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | Ire1의 조절 |
| TW201536293A (zh) | 2013-07-18 | 2015-10-01 | Taiho Pharmaceutical Co Ltd | 對fgfr抑制劑具耐受性之癌的治療藥 |
| EP3023100B1 (en) | 2013-07-18 | 2019-03-13 | Taiho Pharmaceutical Co., Ltd. | Antitumor drug for intermittent administration of fgfr inhibitor |
| DK3068776T3 (da) | 2013-11-13 | 2019-07-29 | Vertex Pharma | Inhibitorer af replikation af influenzavira |
| ES2684755T3 (es) | 2013-11-13 | 2018-10-04 | Vertex Pharmaceuticals Incorporated | Métodos para preparar inhibidores de la replicación de virus de la gripe |
| AU2015296210B2 (en) * | 2014-07-31 | 2019-08-15 | Merck Patent Gmbh | Indolizine derivatives which are applicable to neurodegenerative diseases |
| WO2016183120A1 (en) | 2015-05-13 | 2016-11-17 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
| WO2016183116A1 (en) | 2015-05-13 | 2016-11-17 | Vertex Pharmaceuticals Incorporated | Methods of preparing inhibitors of influenza viruses replication |
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| WO2000039108A1 (en) * | 1998-12-23 | 2000-07-06 | Du Pont Pharmaceuticals Company | Thrombin or factor xa inhibitors |
| CN1279682A (zh) * | 1997-10-20 | 2001-01-10 | 霍夫曼-拉罗奇有限公司 | 双环激酶抑制剂 |
| US20050239820A1 (en) * | 2004-04-26 | 2005-10-27 | Borzilleri Robert M | Bicyclic heterocycles as kinase inhibitors |
| WO2006004984A1 (en) * | 2004-06-30 | 2006-01-12 | Vertex Pharmaceuticals Incorporated | Azaindoles useful as inhibitors of protein kinases |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4326024B2 (ja) * | 1996-03-15 | 2009-09-02 | ノバルティス アクチエンゲゼルシャフト | 新規なN―7―ヘテロサイクリル―ピロロ[2,3―d]ピリミジンおよびこれらの使用 |
| DE69928414T2 (de) * | 1998-09-18 | 2006-08-03 | Abbott Gmbh & Co. Kg | 4-aminopyrrolopyrimidine als kinaseinhibitoren |
| TR200101186T2 (tr) * | 1998-09-18 | 2001-10-22 | Basf Aktiengesellschaft | Protein kinaz engelleyiciler olarak pyrrolopyrimidin'ler |
| US20040235867A1 (en) * | 2001-07-24 | 2004-11-25 | Bilodeau Mark T. | Tyrosine kinase inhibitors |
| US20050026944A1 (en) * | 2003-07-24 | 2005-02-03 | Patrick Betschmann | Thienopyridine and furopyridine kinase inhibitors |
| ATE524467T1 (de) * | 2005-04-25 | 2011-09-15 | Merck Patent Gmbh | Neuartige aza-heterozyklen als kinase-inhibitoren |
-
2007
- 2007-02-12 AU AU2007215161A patent/AU2007215161A1/en not_active Abandoned
- 2007-02-12 JP JP2008555308A patent/JP2009528991A/ja active Pending
- 2007-02-12 EP EP07750595A patent/EP2004645A2/en not_active Withdrawn
- 2007-02-12 US US11/705,556 patent/US7659283B2/en not_active Expired - Fee Related
- 2007-02-12 WO PCT/US2007/003767 patent/WO2007095223A2/en not_active Ceased
- 2007-02-12 CA CA002641254A patent/CA2641254A1/en not_active Abandoned
- 2007-02-12 CN CN200780012623A patent/CN101848909A/zh active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1279682A (zh) * | 1997-10-20 | 2001-01-10 | 霍夫曼-拉罗奇有限公司 | 双环激酶抑制剂 |
| WO2000039108A1 (en) * | 1998-12-23 | 2000-07-06 | Du Pont Pharmaceuticals Company | Thrombin or factor xa inhibitors |
| US20050239820A1 (en) * | 2004-04-26 | 2005-10-27 | Borzilleri Robert M | Bicyclic heterocycles as kinase inhibitors |
| WO2006004984A1 (en) * | 2004-06-30 | 2006-01-12 | Vertex Pharmaceuticals Incorporated | Azaindoles useful as inhibitors of protein kinases |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109071455A (zh) * | 2016-03-11 | 2018-12-21 | 科尔沃斯制药股份有限公司 | 用于调节布鲁顿酪氨酸激酶的化合物及方法 |
| CN109071455B (zh) * | 2016-03-11 | 2022-08-02 | 嘉兴和剂药业有限公司 | 用于调节布鲁顿酪氨酸激酶的化合物及方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2007215161A1 (en) | 2007-08-23 |
| US7659283B2 (en) | 2010-02-09 |
| JP2009528991A (ja) | 2009-08-13 |
| WO2007095223A3 (en) | 2010-06-24 |
| WO2007095223A2 (en) | 2007-08-23 |
| CA2641254A1 (en) | 2007-08-23 |
| EP2004645A2 (en) | 2008-12-24 |
| US20070213327A1 (en) | 2007-09-13 |
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