CN101836653A - Pesticide composition containing amino-oligosaccharide and thiophanate methyl and use method and application thereof - Google Patents
Pesticide composition containing amino-oligosaccharide and thiophanate methyl and use method and application thereof Download PDFInfo
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- CN101836653A CN101836653A CN201010186910A CN201010186910A CN101836653A CN 101836653 A CN101836653 A CN 101836653A CN 201010186910 A CN201010186910 A CN 201010186910A CN 201010186910 A CN201010186910 A CN 201010186910A CN 101836653 A CN101836653 A CN 101836653A
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- oligosaccharide
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Abstract
The invention belongs to the field of pesticides, and relates to a sterilization composition taking amino-oligosaccharide and thiophanate methyl as main active ingredient components, and a use method and application thereof. The composition comprises at least two active ingredients with dosage producing synergistic activity, and appropriate excipients, and is characterized in that the component I is the amino-oligosaccharide, and the component II is the thiophanate methyl. The ratio of weight parts of the amino-oligosaccharide and the thiophanate methyl is 20:1-1:50 in the invention. The preferred scheme is that the ratio of weight parts of the amino-oligosaccharide and the thiophanate methyl is 20:1-1:50. The composition and appropriate excipients are made into any agriculturally available formulation. The preferred formulation is a suspending agent, water dispersible granules and wettable powder. The use method of the invention is that the component I and the component II can be used for treating positions which produce diseases or disease danger in any order or simultaneously. The sterilization composition is used for controlling diseases of fruit, cereal, fruits, vegetables, beans, oil crops and ornamental crops and other crops.
Description
Technical field
The invention belongs to pesticide field, relate to bactericidal composition and using method and application that a kind of main active is amino-oligosaccharide and thiophanate-methyl.
Background technology
The physicochemical property of thiophanate-methyl is as follows:
Chemical name: 1,2-two (3-methoxycarbonyl group-2-ghiourea group) benzene
English name: Thiophanate-Methyl
CAS number: 23564-05-8
Structural formula:
Molecular formula is C
12H
14N
4O
4S
2, molecular weight is 342.4
Thiophanate-methyl belongs to benzimidazole, claims thiophanate methyl, first holder again, is a kind of broad spectrum activity systemic fungicide, can prevent and treat the various crop disease, has interior suction, prevention and therapeutic action.It is converted into carbendazim in plant corpus, the formation of Spindle influences cell division in the mitosis of interference bacterium.Have to top property conduction function, multiple diseases is had prevention and therapeutic action.Tetranychid and pathogenic nematode there is inhibitory action.
According to China's pesticide toxicity grading criteria, thiophanate-methyl belongs to the low toxicity bactericide.Rat acute per os LD
50Be 7500mg/kg (hero) and 6640mg/kg (female).Rat and chmice acute are through skin LD
50＞10000mg/kg.Under experimental condition, do not see mutagenesis, teratogenesis and carcinogenic phenomenon.Rat three-generation test of reproduction no abnormality seen.Thiophanate-methyl is to toxicity in fish, carp LC
50Be 11mg/L (48h), trout LC
50Be 8.8mg/L.To the honeybee low toxicity.Low to birds toxicity.
The pure product of thiophanate-methyl are colourless crystallization, and former powder (content about 93%) is little yellow crystal.Proportion 1.5 (20 ℃), 172 ℃ of fusing points (decomposition), vapour pressure 7.12 * 10
-8MmHg (25 ℃).Water-soluble hardly, dissolve in organic solvents such as acetone, methyl alcohol, ethanol, chloroform.Acid, alkali are stablized.
Methyl is dredged the bacterium spirit has the better prevention effect to the multiple diseases on cereal class, greengrocery, the fruit tree.Especially prevent and treat stinking smut, head blight, rice blast, banded sclerotial blight, sclerotinia rot of colza, sweet potato black rot, cercospora leaf spot of sugar beet, and disease such as cotton, vegetables, flowers.
Thiophanate-methyl has good crop safety and outstanding Environmental compatibility.The formulation products of domestic registration is 50%, 70% wetting powder, 40%, 50% colloidal suspending agent, 36% suspending agent is mainly used in economic crops diseases such as control cereal class, fruit tree, vegetables, because resistance improves, the control efficiency and the application of methyl sulfur bacterium have been had a strong impact in recent years.
Amino-oligosaccharide (oligosaccharins), chemical name: β-1,4-oligomerization-gucosamine, molecular formula: (C
6H
11O
4N) n (n 〉=2), be also referred to as oligosaccharide, shell oligosaccharide, chitosan oligomer, chitan, agricultural chitosan oligosaccharide, it is natural chitinous catabolite, a kind of bactericide that the microorganism belonging to genus metabolism is extracted with resistant effect, pathogen growth there is inhibitory action, but the disease resistance of amino-oligosaccharide inducing plant, multiple fungi, bacterium and virus are produced immunity and killing action, diseases such as wheat mosaic, cotton verticillium wilt, rice blast, tomato late blight are had good preventive and therapeutic effect; Simultaneously, amino-oligosaccharide has to a certain degree direct repression to the pathogen of various plants; In addition, amino-oligosaccharide itself contains abundant C, and N can be utilized by microbial decomposition and as the nutrient of plant growing; Amino-oligosaccharide can change soil microflora, and the promotion beneficial microorganism is grown and suppressed some phytopathogens; But the growth of amino-oligosaccharide stimulating plant makes crops and fruit and vegetable volume increase good harvest.
Amino-oligosaccharide is used characteristics such as have trace (PPM level), efficient, low-cost, nuisanceless on agricultural, significant to China's agricultural sustainability development.
The formulation that amino-oligosaccharide is stepped at present is 0.5%, 1%, 2% aqua.Amino-oligosaccharide exist in actual use the preventive effect effect slowly, to defectives such as the diseases control of having contaminated are not ideal enough.
Summary of the invention
The objective of the invention is to find a kind of control spectrum wide, effect is remarkable, and cost is low, the bactericide good with Environmental compatibility.
Another object of the present invention provides the using method and the purposes of this bactericidal composition.
The object of the invention realizes by following approach:
Bactericidal composition of the present invention comprises at least two kinds of active ingredient components of the dosage that can produce synergistic activity, and proper supplementary material, it is characterized in that components I is an amino-oligosaccharide, and composition is a thiophanate-methyl.
The ratio of weight and number of amino-oligosaccharide and thiophanate-methyl is 20 among the present invention: 1-1: 50.Preferred version is: the ratio of weight and number of amino-oligosaccharide and thiophanate-methyl is 1: 1-1: 25.
The inventor finds, two kinds of components of amino-oligosaccharide and thiophanate-methyl are mixed the back aspect prevention and controlling plant diseases, because amino-oligosaccharide has different mechanism of action with thiophanate-methyl, not only show the additive property effect, enlarge the prevention and treatment range of disease, and had certain synergistic function, reduced dosage, reduce use cost, slowed down the generation of resistance.
The present composition can adopt prior art, according to controlling object, environmental condition, prevent and treat method, factors such as control cost etc., will contain amino-oligosaccharide and thiophanate-methyl and make available any formulation on the agricultural with suitable auxiliary material.Preferred formulation is suspending agent, water dispersible granules, wetting powder.
Proper supplementary material is filler, surfactant or other additive available in preparation technique, can be solid or liquid, the mineral matter, solvent, dispersant, wetting agent, emulsifier, pH regulator agent, stabilizing agent, antifreezing agent, excipient, bleeding agent, binder, thickener, fertilizer, mineral salt of for example natural or regeneration and other are of value to the known substance of active component stable and drug effect performance in preparation, select different auxiliary materials to be mixed with corresponding dosage forms as required.
Surfactant can be nonionic, cation and/or the anion surfactant with well emulsify, dispersion and wetting characteristics, and described surfactant also can be understood as surfactant mixture.
The processing technology of the various preparations of the present composition adopts known method preparation, is method commonly used in the pesticidal preparations processing.
Using method of the present invention is for having produced components I in the described bactericidal composition and composition disease or the position that produces disease danger has been arranged with random order or processing simultaneously.
Composition of the present invention can provide with the form of mixture, and promptly each active component mixes in the composition finished product.Perhaps, each active component also can provide with the form of single agent in the composition, directly mixes in bucket or jar before using, and is diluted to required concentration then and uses, and also each active component list agent can be diluted respectively, is applied to the control position of crop separately.
Usually the amino-oligosaccharide and the thiophanate-methyl that contain 0.1-99%, especially 0.1-95% in the agrochemical composition, 99.9-1%, the especially solid of 99.9-5% or Auxiliary Liquid Material and 0-25%, the surfactant of 0.1-25% especially.
Though the preferred concentrate formulation of commercial product, the end user normally uses preparation dilution back.
Bactericidal composition of the present invention is applied to prevent and treat crop pests such as fruit tree, cereal class, melon and fruit class, greengrocery, beans, oil crop and ornamental crops.
Concrete embodiment
In order to understand the present invention better, describe the technology contents of invention below in detail with example, but embodiment of the present invention are not limited to these examples.
Embodiment 1
Take by weighing each component raw material according to following proportioning
60 parts of amino-oligosaccharides
3 parts of thiophanate-methyls
8 parts of calcium lignosulfonates
6 parts of octyl phenol polyglycol ethers
0.5 part of gum Arabic
22.5 parts of kaolin
With the said components mixing, through pulverizing the female powder of preparation, female powder and suitable quantity of water solution are mixed, carry out extruder grain then, dry, analytical control warehouse-in obtains the water dispersible granules of amino-oligosaccharide and thiophanate-methyl.
Embodiment 2
Take by weighing each component raw material according to following proportioning
0.5 part of amino-oligosaccharide
25 parts of thiophanate-methyls
6 parts of sodium lignin sulfonates
4 parts of nonyl phenol polyoxyethylene polyoxypropylene ethers
3 parts of xanthans
8 parts of glycerine
53.5 parts in water
Said components mixing, sand milling, analytical control warehouse-in are obtained the suspending agent of amino-oligosaccharide and thiophanate-methyl.
Embodiment 3
Take by weighing each component raw material according to following proportioning
25 parts of amino-oligosaccharides
25 parts of thiophanate-methyls
4 parts of dodecyldimethylammonium hydroxide inner salts
6 parts of perfluoroalkyl ethyoxyl ether alcohols
30 parts of white carbons
10 parts of potassium dihydrogen phosphates
With the said components mixing, process is crushed to suitable fineness, the wetting powder that obtains amino-oligosaccharide and thiophanate-methyl is put in analytical control in storage.
Embodiment 4
Take by weighing each component raw material according to following proportioning
60 parts of amino-oligosaccharides
6 parts of thiophanate-methyls
7 parts of sodium lignin sulfonates
3 parts of dispersing agent NNOs
2 parts of azones
8 parts in ammonium sulfate
13 parts of bentonites
1 part of low-substituted hydroxypropyl cellulose
With the said components mixing, through pulverizing the female powder of preparation, female powder and suitable quantity of water solution are mixed, carry out fluidized bed prilling then, drying, screening, analytical control warehouse-in obtain the water dispersible granules of amino-oligosaccharide and the thin bacterium spirit of methyl.
Embodiment 5
Take by weighing each component raw material according to following proportioning
3 parts of amino-oligosaccharides
75 parts of thiophanate-methyls
9 parts of dispersant D9
4 parts of dispersant D-425
1 part of polyvinylpyrrolidone
7 parts of white carbons
1 part of xanthans
With the said components mixing,, female powder and suitable quantity of water solution are mixed through pulverizing the female powder of preparation. carry out fluidized bed prilling then, drying, screening, analytical control warehouse-in obtain the water dispersible granules of amino-oligosaccharide and thiophanate-methyl.
Embodiment 6
Take by weighing each component raw material according to following proportioning
3 parts of amino-oligosaccharides
30 parts of thiophanate-methyls
7 parts of perfluoroalkyl ethyoxyl ether alcohols
4 parts of neopelexes
1 part of polyvinylpyrrolidone
38 parts of attapulgites
2 parts of hydroxypropyl celluloses
15 parts in urea
With the said components mixing, through pulverizing the female powder of preparation, female powder and suitable quantity of water solution are mixed, carry out fluidized bed prilling then, obtain the water dispersible granules of amino-oligosaccharide and thiophanate-methyl in dry, screening, analytical control warehouse-in.
Embodiment 7 present embodiments are the field efficacy Application Example.
Amino-oligosaccharide and thiophanate-methyl series proportioning control rice blast field control effectiveness test.
1 test is handled: this experimental pharmacy dosage is according to table 1, and the contrast medicament is respectively commercially available 0.5% amino-oligosaccharide aqua and 70% thiophanate-methyl wetting powder.Blank is tested with clear water.
2 test methods: the test region sprays medicine 5 times altogether in the time of infertility of paddy rice.
3 in test region and blank district (CK), more than 500 strains of picked at random paddy rice, writes down total strain number and the diseased plant number of every strain paddy rice.
4 drug effect computational methods
* 100% is counted in diseased plant rate (%)=diseased plant number/total strain of investigation
Control efficiency (%)=(blank district diseased plant rate-treatment region diseased plant rate)/blank district diseased plant rate * 100%
5 experimental results
Table 1 amino-oligosaccharide and thiophanate-methyl are to the field test results of rice blast
| Test medicine | Dosage (g/hm 2) | Investigate total strain number (individual) | Diseased plant number (individual) | Diseased plant rate (%) | Control efficiency (%) |
| 0.5% amino-oligosaccharide aqua | ??32 | ??510 | ??35 | ??6.86 | ??33.59 |
| 70% thiophanate-methyl wetting powder | ??106 | ??536 | ??28 | ??5.22 | ??49.47 |
| Embodiment 2 | ??101 | ??517 | ??8 | ??1.55 | ??84.99 |
| Embodiment 1 | ??95 | ??521 | ??12 | ??2.30 | ??77.73 |
| Embodiment 4 | ??103 | ??538 | ??11 | ??2.04 | ??80.25 |
| Embodiment 5 | ??92 | ??551 | ??7 | ??1.27 | ??87.70 |
| Embodiment 6 | ??90 | ??543 | ??6 | ??1.10 | ??89.35 |
| Embodiment 3 | ??97 | ??549 | ??10 | ??1.82 | ??82.38 |
| ??CK | ??- | ??552 | ??57 | ??10.33 | ??- |
By the result of the test of table 1 as can be seen, amino-oligosaccharide and the agent of thiophanate-methyl list are respectively 33.59% to the preventive effect of paddy rice powdery mildew, 49.47%, and amino-oligosaccharide of the present invention and thiophanate-methyl composition increase significantly on preventive effect, preventive effect is up to 89.35%, minimumly also reached 77.73%, particularly the weight ratio of amino-oligosaccharide and thiophanate-methyl is 1: 1-1: 25 (embodiment 2,3,5,6) time, preventive effect has reached 82.38%-89.35%, therefore amino-oligosaccharide of the present invention and thiophanate-methyl composition have the control spectrum extensively, effect is remarkable, cost is low, has reached its intended purposes.
Though more than described various embodiment of the present invention, should be appreciated that its purpose only is to illustrate, and do not have restricted.Those skilled in the art knows, not leaving under the spirit and scope of the present invention situation, also can make various changes in the form and details.Therefore, protection scope of the present invention is improper only to be confined to arbitrary embodiment described above, limits and should and be equal to according to claim.
Claims (7)
1. bactericidal composition, it comprises at least two kinds of active ingredient components of the dosage that can produce synergistic activity, and proper supplementary material, it is characterized in that components I is an amino-oligosaccharide, composition is a thiophanate-methyl.
2. bactericidal composition according to claim 1, the ratio of weight and number that it is characterized in that amino-oligosaccharide and thiophanate-methyl is 20: 1-1: 50.
3. bactericidal composition according to claim 2, the ratio of weight and number that it is characterized in that amino-oligosaccharide and thiophanate-methyl is 1: 1-1: 25.
4. according to claim 1,2 or 3 described bactericidal compositions, it is characterized in that amino-oligosaccharide and thiophanate-methyl and suitable auxiliary material make agricultural and go up available any formulation.
5. bactericidal composition according to claim 4 is characterized in that described formulation is suspending agent, water dispersible granules, wetting powder.
6. the method for preventing and treating and preventing plant disease is characterized in that components I in the described bactericidal composition of claim 1 and composition have been produced disease or the position that produces disease danger is arranged with random order or processing simultaneously.
7. the described bactericidal composition of claim 1, the application on crop pests such as control fruit tree, cereal class, melon and fruit class, greengrocery, beans, oil crop and ornamental crops.
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| CN201010186910A CN101836653A (en) | 2010-05-28 | 2010-05-28 | Pesticide composition containing amino-oligosaccharide and thiophanate methyl and use method and application thereof |
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Cited By (3)
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| CN103798260A (en) * | 2014-02-19 | 2014-05-21 | 罗晓丹 | Method for preventing and curing root-knot nematode by utilizing benfuracarb and amino-oligosaccharin |
| CN103798259A (en) * | 2014-02-19 | 2014-05-21 | 罗晓丹 | Nematicide containing benfuracarb and amino-oligosaccharin |
| CN107518060A (en) * | 2017-07-20 | 2017-12-29 | 江苏师范大学 | A kind of chitosan oligosaccharide preparation and its application in black spot preventing and treating after sweet potato is adopted |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103798260A (en) * | 2014-02-19 | 2014-05-21 | 罗晓丹 | Method for preventing and curing root-knot nematode by utilizing benfuracarb and amino-oligosaccharin |
| CN103798259A (en) * | 2014-02-19 | 2014-05-21 | 罗晓丹 | Nematicide containing benfuracarb and amino-oligosaccharin |
| CN103798260B (en) * | 2014-02-19 | 2015-06-03 | 河南科技学院 | Method for preventing and curing root-knot nematode by utilizing benfuracarb and amino-oligosaccharin |
| CN103798259B (en) * | 2014-02-19 | 2015-06-17 | 河南科技学院 | Nematicide containing benfuracarb and amino-oligosaccharin |
| CN107518060A (en) * | 2017-07-20 | 2017-12-29 | 江苏师范大学 | A kind of chitosan oligosaccharide preparation and its application in black spot preventing and treating after sweet potato is adopted |
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Application publication date: 20100922 |