CN101835486B - 用于治疗创伤的药物组合物以及相关方法 - Google Patents

用于治疗创伤的药物组合物以及相关方法 Download PDF

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Publication number
CN101835486B
CN101835486B CN2008801012390A CN200880101239A CN101835486B CN 101835486 B CN101835486 B CN 101835486B CN 2008801012390 A CN2008801012390 A CN 2008801012390A CN 200880101239 A CN200880101239 A CN 200880101239A CN 101835486 B CN101835486 B CN 101835486B
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seq
insulin
pkc
compositions
arg
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Expired - Fee Related
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CN2008801012390A
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Chinese (zh)
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CN101835486A (zh
Inventor
T·滕宁鲍姆
L·布赖曼-维克斯曼
I·索罗莫尼克
O·莱维-哈查姆
E·布雷纳
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Healor Ltd
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Healor Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN2008801012390A 2007-07-30 2008-07-30 用于治疗创伤的药物组合物以及相关方法 Expired - Fee Related CN101835486B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US96270607P 2007-07-30 2007-07-30
US60/962,706 2007-07-30
US60/962706 2007-07-30
PCT/IL2008/001049 WO2009016629A2 (en) 2007-07-30 2008-07-30 Pharmaceutical composition for treating wounds and related methods

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN2012102198145A Division CN102755649A (zh) 2007-07-30 2008-07-30 药物组合物及相关方法

Publications (2)

Publication Number Publication Date
CN101835486A CN101835486A (zh) 2010-09-15
CN101835486B true CN101835486B (zh) 2012-12-12

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CN2008801012390A Expired - Fee Related CN101835486B (zh) 2007-07-30 2008-07-30 用于治疗创伤的药物组合物以及相关方法
CN2012102198145A Pending CN102755649A (zh) 2007-07-30 2008-07-30 药物组合物及相关方法

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US (3) US20100310542A1 (enExample)
EP (2) EP2653166A3 (enExample)
JP (3) JP5411857B2 (enExample)
KR (2) KR20100040912A (enExample)
CN (2) CN101835486B (enExample)
AU (1) AU2008281374B2 (enExample)
CA (1) CA2694927A1 (enExample)
NZ (1) NZ582556A (enExample)
RU (2) RU2502520C2 (enExample)
WO (1) WO2009016629A2 (enExample)

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ES2375565T3 (es) 2003-08-07 2012-03-02 Healor Ltd. Composiciones farmacéuticas y métodos para acelerar la cicatrización de heridas.
WO2007026356A2 (en) * 2005-08-29 2007-03-08 Healor Ltd. Methods and compositions for prevention and treatment of diabetic and aged skin
WO2011011808A1 (en) * 2009-07-30 2011-02-03 Roman Buga A cosmetic composition comprising sodium chloride in combination with one or more of protein, collagen, gelatin or amino acid
US8889615B2 (en) 2009-12-31 2014-11-18 New York University Methods for promoting epithelialization and healing of chronic wounds
EP2599494A1 (en) 2010-01-11 2013-06-05 Healor Ltd. PKC inhibitors for the treatment of inflammatory disease or disorder
CN104758921A (zh) * 2010-11-08 2015-07-08 希尔洛有限公司 缓冲的眼用组合物以及使用其的方法
US10342891B2 (en) * 2013-09-19 2019-07-09 Medline Industries, Inc. Wound dressing containing saccharide and collagen
BR112016017444A2 (pt) * 2014-01-29 2017-10-10 Inst Nat Sante Rech Med molécula e método
EP3421485A1 (en) 2017-06-30 2019-01-02 Université de Strasbourg Peptides for treatment and prevention of hyperglycaemia
RU2766292C1 (ru) * 2021-08-05 2022-03-14 Федеральное государственное унитарное предприятие "Санкт-Петербургский научно-исследовательский институт вакцин и сывороток и предприятие по производству бактерийных препаратов" Федерального медико-биологического агентства (ФГУП СПбНИИВС ФМБА России) Состав вакцины против covid-19

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US20140227243A1 (en) 2014-08-14
KR20130121678A (ko) 2013-11-06
US20130336952A1 (en) 2013-12-19
JP2013144697A (ja) 2013-07-25
JP5411857B2 (ja) 2014-02-12
JP2010535194A (ja) 2010-11-18
AU2008281374B2 (en) 2012-05-31
RU2502520C2 (ru) 2013-12-27
WO2009016629A2 (en) 2009-02-05
NZ582556A (en) 2013-02-22
RU2010106661A (ru) 2011-09-10
RU2013142159A (ru) 2015-03-27
EP2653166A2 (en) 2013-10-23
WO2009016629A3 (en) 2009-05-22
KR20100040912A (ko) 2010-04-21
CN101835486A (zh) 2010-09-15
EP2185184A2 (en) 2010-05-19
US20100310542A1 (en) 2010-12-09
HK1148467A1 (en) 2011-09-09
EP2653166A3 (en) 2014-08-27
CN102755649A (zh) 2012-10-31
CA2694927A1 (en) 2009-02-05
JP2014024862A (ja) 2014-02-06
AU2008281374A1 (en) 2009-02-05

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