CN101810340A - Angelica keiskei soft capsule - Google Patents

Angelica keiskei soft capsule Download PDF

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Publication number
CN101810340A
CN101810340A CN201010154941A CN201010154941A CN101810340A CN 101810340 A CN101810340 A CN 101810340A CN 201010154941 A CN201010154941 A CN 201010154941A CN 201010154941 A CN201010154941 A CN 201010154941A CN 101810340 A CN101810340 A CN 101810340A
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China
Prior art keywords
angelica keiskei
soft capsule
parts
keiskei
powder
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Pending
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CN201010154941A
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Chinese (zh)
Inventor
陈显刚
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Individual
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Individual
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Priority to CN201010154941A priority Critical patent/CN101810340A/en
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  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses an angelica keiskei soft capsule. The contents of the soft capsule include the following raw materials in part by weight: 10 to 80 parts of angelica keiskei superfine powder or angelica keiskei water extract powder, 20 to 80 parts of corn oil or soybean oil, 2 to 15 parts of vitamin E and 0.1 to 8 parts of beeswax. Compared with the prior art, the angelica keiskei soft capsule perfectly maintains various extremely unique and rare natural substances such as chalcone, natural flavone, natural organic germanium, vitamin B12, growth factor NGF capable of enhancing the activity of the human nerve cells by 20 times and the like by using a superfine milling cell wall breaking technique and particularly crushing at the temperature of between 15 and 40 DEG C below zero, thereby greatly improving the utilization rate of the biological active material in the angelica keiskei; due to the adoption of the form of soft capsule, not only the uncomfortable smell of the angelica keiskei can be covered, but also oxygen can be prevented from entering so as to improve the stability of the active ingredient which is easy to become deteriorated when exposed to air; the active ingredient has a long storage period; and the soft capsule is convenient to take and easy to carry.

Description

A kind of angelica keiskei soft capsule
Technical field
The present invention relates to a kind of health products, be specifically related to a kind of angelica keiskei soft capsule.
Background technology
Angelica Keiskei (Angelica Keiskei Koidzumi), original producton location be on eight zhang islands, township of the famous good health and a long life of Japan, belongs to primary celery section herbaceos perennial.Because of its vitality is strong, growth is fast, the gesture of " today priming leaf, tomorrow long again sprouting " is arranged, so title " Angelica Keiskei " greatly.It is edible that its young stem and leaf can be done vegetables, but the herb hyoscine.Angelica Keiskei is described as " healthy food of 21 century ", is rich in several mineral materials, food fiber, protein, vitamin, chlorophyll, carrotene and 16 gynaminic acid that endemic element chalcone and cumarin and human body need.Find that according to the study Angelica Keiskei contains anti-human senility, thrombus, cancer, 26 kinds of diseases can be treated and prevent to hypoglycemic, blood pressure, courage and improve composition such as intestines and stomach function, wherein hypoglycemic, the blood pressure effect is the most obvious.
Existing processing to Angelica Keiskei is admired based on tea making or tea and is expected, people drink after angelica keiskei tea is soaked, though this processing mode also can reach the purpose of drawing active ingredient in the Angelica Keiskei, but because the immersion of tea needs hot water, and needing the operation of immersion together, this makes drinking of angelica keiskei tea be subjected to certain restriction.Drink for convenience, angelica keiskei tea beverage products thereby arise at the historic moment, but it carries and is not very convenient; In addition, the flavour of a drug of active component are denseer in the Angelica Keiskei, do not accepted by some consumers with the product of tea beverage form.
Soft capsule is a kind of novel form that grows up behind sheet, injection, system is with the quantitative pressure injection of oily medicine, drug solution or drug suspension, pastel even drug powder and be encapsulated in the glued membrane, form big or small, different seal capsule, available dropping preparation method or pressing preparation.Yet there are no the open report of angelica keiskei soft capsule.
Summary of the invention
The technical problem to be solved in the present invention provides a kind of angelica keiskei soft capsule, the reservation that this soft capsule is more intact active component in the Angelica Keiskei, be easy to absorb and easy to carry.
In order to solve the problems of the technologies described above, the present invention by the following technical solutions:
A kind of angelica keiskei soft capsule is characterized in that the content of this soft capsule is made by the following weight proportion raw material:
Angelica Keiskei ultra micro powder or Angelica Keiskei the water extracted immersing paste powder 10~80, corn oil or soybean oil 20~80, vitamin E 2~15, beeswax 0.1~8.
The weight proportion of preferred each raw material is:
Angelica Keiskei ultra micro powder or Angelica Keiskei the water extracted immersing paste powder 20~60, corn oil or soybean oil 30~70, vitamin E 2~10, beeswax 1~8.
The weight proportion of more preferred each raw material is:
Angelica Keiskei ultra micro powder or Angelica Keiskei the water extracted immersing paste powder 30~50, corn oil or soybean oil 40~60, vitamin E 5~10, beeswax 1~5.
In the above-mentioned prescription,
The granularity of Angelica Keiskei ultra micro powder and Angelica Keiskei the water extracted immersing paste powder all is to be advisable with 200~300 orders.
Described Angelica Keiskei the water extracted immersing paste powder is to get dried tomorrow of base of leaf and leaf, adds the water boiling and extraction 1~3 time of 3~10 times of raw material weights, extracts 0.5~3 hour at every turn, merges extract, concentrates, and pulverizes behind the vacuum spray drying to make.
Described Angelica Keiskei ultra micro powder is preferably pulverized under-15~-40 ℃ temperature conditions and is obtained.
The capsule shells of angelica keiskei soft capsule of the present invention is existing conventional soft capsule shell, and described soft capsule can prepare by existing conventional technology.
Compared with prior art, the invention has the advantages that:
1, adopts the method for ultramicro grinding breaking-wall cell, especially under-15~-40 ℃ temperature conditions, pulverize, intact reservation chalcone, natural flavone, natural organic germanium, cobalamin, dietary fiber, can strengthen multiple very unique famous and precious natural materials such as growth factor NGF of active 20 times of human neuronal cell line, thereby improve the availability of bioactivator in the Angelica Keiskei greatly;
No matter 2 is with Angelica Keiskei ultramicro grinding breaking-wall cell, still the mode of carrying with water extracts the active ingredient in the Angelica Keiskei, and what it finally all sealed places in the soft capsule, and the present invention both can cover the foreign odor of Angelica Keiskei itself by the form of soft capsule; Can prevent that again oxygen from entering, improve the stability of meeting the perishable active component of air in the Angelica Keiskei, and make active component have longer storage period;
3, taking convenience and being easy to carry about with one.
The specific embodiment
The invention will be further described with embodiment below, but the present invention is not limited to these embodiment.
Below umber among each embodiment be weight portion.
Embodiment 1
One, angelica keiskei soft capsule content prescription:
100 10 parts in purpose Angelica Keiskei ultra micro powder, 80 parts of corn oils, 10 parts of vitamin Es, 5 parts in beeswax.
Two, angelica keiskei soft capsule preparation method
Get dried tomorrow of base of leaf and leaf, under-20 ℃ of conditions, be crushed to 100 orders with micronizer, conventional sterilization; Angelica Keiskei ultra micro powder after the sterilization is mixed with corn oil, grind well, make Angelica Keiskei ultra micro powder be suspended in the corn oil uniformly through colloid mill; Technology glue routinely rolls the mold pressing method for making and prepares angelica keiskei soft capsule by existing.
But the soft capsule can of Sheng Chaning is size specifications such as every of content 450mg or 800mg as required.
Embodiment 2
One, angelica keiskei soft capsule content prescription:
300 60 parts in purpose Angelica Keiskei ultra micro powder, 20 parts of corn oils, 15 parts of vitamin Es, 1 part in beeswax.
Two, angelica keiskei soft capsule preparation method
Get dried tomorrow of base of leaf and leaf, under-45 ℃ of conditions, be crushed to 300 orders with micronizer, conventional sterilization; Angelica Keiskei ultra micro powder after the sterilization is mixed with corn oil, grind well, make Angelica Keiskei ultra micro powder be suspended in the corn oil uniformly through colloid mill; Technology glue routinely rolls the mold pressing method for making and prepares angelica keiskei soft capsule by existing again.
But the soft capsule can of Sheng Chaning is size specifications such as every of content 450mg or 800mg as required.
Embodiment 3
One, angelica keiskei soft capsule content prescription:
400 80 parts in order Angelica Keiskei ultra micro powder, 60 parts of soybean oils, 5 parts of vitamin Es, 0.1 part in beeswax.
Two, angelica keiskei soft capsule preparation method
Get dried tomorrow of base of leaf and leaf, under-15 ℃ of conditions, be crushed to 400 orders with micronizer, conventional sterilization; Angelica Keiskei ultra micro powder after the sterilization is mixed with soybean oil, grind well, make Angelica Keiskei ultra micro powder be suspended in the soybean oil uniformly through colloid mill; Technology glue routinely rolls the mold pressing method for making and prepares angelica keiskei soft capsule by existing again.
But the soft capsule can of Sheng Chaning is size specifications such as every of content 450mg or 800mg as required.
Embodiment 4
One, angelica keiskei soft capsule content prescription:
200 30 parts in purpose Angelica Keiskei ultra micro powder, 30 parts of soybean oils, 2 parts of vitamin Es, 8 parts in beeswax.
Two, angelica keiskei soft capsule preparation method
Get dried tomorrow of base of leaf and leaf, under-30 ℃ of conditions, be crushed to 200 orders with micronizer, conventional sterilization; Angelica Keiskei ultra micro powder after the sterilization is mixed with soybean oil, grind well, make Angelica Keiskei ultra micro powder be suspended in the soybean oil uniformly through colloid mill; Technology glue prepares angelica keiskei soft capsule by existing pressing more routinely.
But the soft capsule can of Sheng Chaning is size specifications such as every of content 450mg or 800mg as required.
Embodiment 5
One, angelica keiskei soft capsule content prescription:
250 45 parts in purpose Angelica Keiskei ultra micro powder, 70 parts of soybean oils, 8 parts of vitamin Es, 2 parts in beeswax.
Two, angelica keiskei soft capsule preparation method
Get dried tomorrow of base of leaf and leaf, under normal temperature, be crushed to 150 orders with micronizer, conventional sterilization; Angelica Keiskei ultra micro powder after the sterilization is mixed with soybean oil, grind well, make Angelica Keiskei ultra micro powder be suspended in the soybean oil uniformly through colloid mill; Technology glue routinely rolls the mold pressing method for making and prepares angelica keiskei soft capsule by existing again.
But the soft capsule can of Sheng Chaning is size specifications such as every of content 450mg or 800mg as required.
Embodiment 6
One, angelica keiskei soft capsule content prescription:
300 20 parts in purpose Angelica Keiskei the water extracted immersing paste powder, 40 parts of corn oils, 4 parts of vitamin Es, 0.5 part in beeswax.
Two, angelica keiskei soft capsule preparation method
Get dried tomorrow of base of leaf and leaf, add the water boiling and extraction 3 hours of 10 times of raw material weights, filter, extract is concentrated into medicinal extract, is crushed to 300 orders behind the vacuum spray drying, obtains Angelica Keiskei the water extracted immersing paste powder, conventional sterilization; Angelica Keiskei the water extracted immersing paste powder after the sterilization is mixed with corn oil, grind well, make Angelica Keiskei ultra micro powder be suspended in the corn oil uniformly through colloid mill; Technology glue routinely rolls the mold pressing method for making and prepares angelica keiskei soft capsule by existing again.
But the soft capsule can of Sheng Chaning is size specifications such as every of content 450mg or 800mg as required.
Embodiment 7
One, angelica keiskei soft capsule content prescription:
200 50 parts in purpose Angelica Keiskei the water extracted immersing paste powder, 75 parts of corn oils, 12 parts of vitamin Es, 6 parts in beeswax.
Two, angelica keiskei soft capsule preparation method
Get dried tomorrow of base of leaf and leaf, add water boiling and extraction 2 times, extract for the first time 2 hours (addition of water is 8 times of raw material weight), extract 1 hour (addition of water is 3 times of raw material weight) the 2nd time, filter, merge extract, be concentrated into 15 Baume degrees, be crushed to 200 orders behind the vacuum spray drying, obtain Angelica Keiskei the water extracted immersing paste powder, conventional sterilization; Angelica Keiskei the water extracted immersing paste powder after the sterilization is mixed with corn oil, grind well, make Angelica Keiskei ultra micro powder be suspended in the corn oil uniformly through colloid mill; Technology glue prepares angelica keiskei soft capsule by existing pressing more routinely.
But the soft capsule can of Sheng Chaning is size specifications such as every of content 450mg or 800mg as required.
Embodiment 8
One, angelica keiskei soft capsule content prescription:
350 70 parts in purpose Angelica Keiskei the water extracted immersing paste powder, 25 parts of soybean oils, 15 parts of vitamin Es, 3 parts in beeswax.
Two, angelica keiskei soft capsule preparation method
Get dried tomorrow of base of leaf and leaf, add water boiling and extraction 3 times, extract for the first time 1.5 hours (addition of water is 5 times of raw material weight), extract 1 hour (addition of water is 3 times of raw material weight) the 2nd time, 0.5 hour (addition of water is 1 times of raw material weight) of the 3rd extraction merges extract, be concentrated into 10 Baume degrees, be crushed to 200 orders behind the vacuum spray drying, obtain Angelica Keiskei the water extracted immersing paste powder, conventional sterilization; Angelica Keiskei the water extracted immersing paste powder after the sterilization is mixed with soybean oil, grind well, make Angelica Keiskei ultra micro powder be suspended in the soybean oil uniformly through colloid mill; Technology glue routinely rolls the mold pressing method for making and prepares angelica keiskei soft capsule by existing again.
But the soft capsule can of Sheng Chaning is size specifications such as every of content 450mg or 800mg as required.

Claims (6)

1. angelica keiskei soft capsule is characterized in that the content of this soft capsule is made by the following weight proportion raw material:
Angelica Keiskei ultra micro powder or Angelica Keiskei the water extracted immersing paste powder 10~80, corn oil or soybean oil 20~80, vitamin E 2~15, beeswax 0.1~8.
2. angelica keiskei soft capsule according to claim 1 is characterized in that the weight proportion of each raw material is:
Angelica Keiskei ultra micro powder or Angelica Keiskei the water extracted immersing paste powder 20~60, corn oil or soybean oil 30~70, vitamin E 2~10, beeswax 1~8.
3. angelica keiskei soft capsule according to claim 2 is characterized in that the weight proportion of each raw material is:
Angelica Keiskei ultra micro powder or Angelica Keiskei the water extracted immersing paste powder 30~50, corn oil or soybean oil 40~60, vitamin E 5~10, beeswax 1~5.
4. according to any one described angelica keiskei soft capsule in the claim 1~3, it is characterized in that: the granularity of Angelica Keiskei ultra micro powder and Angelica Keiskei the water extracted immersing paste powder is 200~300 orders.
5. according to any one described angelica keiskei soft capsule in the claim 1~3, it is characterized in that: described Angelica Keiskei the water extracted immersing paste powder is to get dried tomorrow of base of leaf and leaf, the water boiling and extraction that the adding raw material weight is 3~10 times 1~3 time, the each extraction 0.5~3 hour, merge extract, concentrate, pulverizing makes behind the vacuum spray drying.
6. according to any one described angelica keiskei soft capsule in the claim 1~3, it is characterized in that: the pulverizing temperature of Angelica Keiskei ultra micro powder is-15~-40 ℃.
CN201010154941A 2010-04-23 2010-04-23 Angelica keiskei soft capsule Pending CN101810340A (en)

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Application Number Priority Date Filing Date Title
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102326776A (en) * 2011-08-31 2012-01-25 上海交通大学 Angelica keiskei health-care chewable tablet and preparation method thereof
CN102871195A (en) * 2012-09-17 2013-01-16 上海交通大学 Angelica keiskei kidz effervescence medicine slice rich in flavone and preparation method thereof
CN103704701A (en) * 2013-12-30 2014-04-09 徐州绿之野生物食品有限公司 Angelica keiskei capsule and preparation method thereof
CN103750318A (en) * 2014-01-16 2014-04-30 上海交通大学 Ashitaba mixed soft capsule and preparation method thereof
CN108029820A (en) * 2017-12-08 2018-05-15 浙江省农业科学院 A kind of Angelica Keiskei mixing green juice powder and its preparation method and application

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1287836A (en) * 2000-07-10 2001-03-21 山东东阿阿胶股份有限公司 Doukey-hide gelatin capsule
JP2006025630A (en) * 2004-07-13 2006-02-02 Japan Organo Co Ltd Functional food
CN101396054A (en) * 2007-07-18 2009-04-01 宝生物工程株式会社 Angelica keiskei tea

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1287836A (en) * 2000-07-10 2001-03-21 山东东阿阿胶股份有限公司 Doukey-hide gelatin capsule
JP2006025630A (en) * 2004-07-13 2006-02-02 Japan Organo Co Ltd Functional food
CN101396054A (en) * 2007-07-18 2009-04-01 宝生物工程株式会社 Angelica keiskei tea

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102326776A (en) * 2011-08-31 2012-01-25 上海交通大学 Angelica keiskei health-care chewable tablet and preparation method thereof
CN102326776B (en) * 2011-08-31 2012-12-12 上海交通大学 Angelica keiskei health-care chewable tablet and preparation method thereof
CN102871195A (en) * 2012-09-17 2013-01-16 上海交通大学 Angelica keiskei kidz effervescence medicine slice rich in flavone and preparation method thereof
CN102871195B (en) * 2012-09-17 2014-07-09 上海交通大学 Angelica keiskei kidz effervescence medicine slice rich in flavone and preparation method thereof
CN103704701A (en) * 2013-12-30 2014-04-09 徐州绿之野生物食品有限公司 Angelica keiskei capsule and preparation method thereof
CN103704701B (en) * 2013-12-30 2016-04-06 江苏鑫瑞源食品有限公司 A kind of angelica keiskei capsule and preparation method
CN103750318A (en) * 2014-01-16 2014-04-30 上海交通大学 Ashitaba mixed soft capsule and preparation method thereof
CN103750318B (en) * 2014-01-16 2015-07-08 上海交通大学 Ashitaba mixed soft capsule and preparation method thereof
CN108029820A (en) * 2017-12-08 2018-05-15 浙江省农业科学院 A kind of Angelica Keiskei mixing green juice powder and its preparation method and application

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Application publication date: 20100825