CN101804224A - Medical instrument-combined electric pulse introduction device - Google Patents

Medical instrument-combined electric pulse introduction device Download PDF

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Publication number
CN101804224A
CN101804224A CN 201010139280 CN201010139280A CN101804224A CN 101804224 A CN101804224 A CN 101804224A CN 201010139280 CN201010139280 CN 201010139280 CN 201010139280 A CN201010139280 A CN 201010139280A CN 101804224 A CN101804224 A CN 101804224A
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China
Prior art keywords
medicine
injection
electric pulse
needle
syringe needle
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CN 201010139280
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Chinese (zh)
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CN101804224B (en
Inventor
陈丽晔
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SHANGHAI TERESA BIO-TECH CO., LTD.
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陈丽晔
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Abstract

The invention discloses a medical instrument-combined electric pulse introduction device, which achieves the joint completion of medicine injection and electric pulse stimulation so that a patient only needs to be subject to needle injection once. The technical proposal thereof is that: the device comprises: a housing; an electrode cell, positioned on a base at the front end of the housing and connected with an electric pulse generation device via an electrically conductive post to receive electric pulse signals; a needle group, positioned at the foremost end of the housing and comprising an injection needle and a plurality of electrode introduction needles, wherein the electrode introduction needles are all connected with the electrode cell and implement electric introduction through electric pulse, and the injection needle is used for medicine injection; a medicine refill, positioned inside the housing and internally equipped with a plurality of medicine injection units, which are arrayed in a line, connected with each other via reverse wedging members and provided with injection holes at the front ends thereof, wherein the injection hole of the medicine injection unit at the foremost end is communicated with the injection needle, and the rear end of the medicine refill is provided with an injector pushing rod which is connected with the medicine injection unit at the rearmost end of the medicine refill.

Description

The bonded electric pulse gatherer of medical instruments
Technical field
The present invention relates to a kind of medical instruments coupling apparatus, relate in particular to a kind of the realization medicine importing and electric pulse are imported the device that combines.
Background technology
The applicant on July 10th, 2007 to Patent Office of the People's Republic of China submitted that application number is 200710043612.9 to, denomination of invention is the patent application of " a kind of electroporation leading-in apparatus of medicine ", and on January 14th, 2009 open (publication number is CN 101342390A).
This application discloses a kind of electroporation leading-in apparatus of medicine, has improved the importing effect of vaccine medicine, has reduced the use amount of medicine, reduces the untoward reaction of medicine.Its technical scheme is: electroporation leading-in apparatus, medicine is imported target tissue by low-frequency electric pulse, and comprising: pulse is provided with module, receives the electric pulse parameter of user's input; Power module produces a direct current signal of telecommunication; Microcontroller, received pulse are provided with the electric pulse parameter of module, export a control signal according to electric pulse parameter; The pulse generation module receives the control signal that microcontroller is exported, and the dc signal that this power module is supplied with is processed into electric impulse signal and output; Load, the electric impulse signal of received pulse generation module output.
The method of using this electroporation leading-in apparatus is that injectable drug and electrode importing are two steps of separating, that is: carry out the medicine injection with injection needle earlier, the syringe needle of this electroporation leading-in apparatus of reuse (load just), the electric pulse that device is produced imports in the tissue that receives the medicine injection, is beneficial to medicine and enters histiocyte more smoothly.
The weak point of above-mentioned gatherer and introduction method is need carry out double injection for patient, that is: to its injectable drug, be for the second time to export syringe needle by the electric pulse of electroporation leading-in apparatus it is carried out the stimulation of electric pulse by injection needle the first time.Patient must bear the misery of twice needle injection.
Summary of the invention
The objective of the invention is to address the above problem, provide a kind of medicine wedge bonded electric pulse gatherer, it makes injectable drug and electric pulse stimulation combine and finishes, and only need stand one time needle injection concerning patient.
Technical scheme of the present invention is: the present invention has disclosed the bonded electric pulse gatherer of a kind of medical instruments, comprising:
Shell;
Slot electrode is positioned on the pedestal of this shell front end, and the electric pulse generator outer by electric conductance post and device is connected, and receives the electric impulse signal of electric pulse generator output;
The syringe needle group, be positioned at this shell foremost, several electrodes that comprise an injection needle and periphery import syringe needle, this injection needle and this several electrodes import syringe needle and all are connected with this slot electrode, wherein these several electrodes importing syringe needles receive by the electric pulse of this slot electrode conduction to go into to implement electric conductance, and this injection needle is used for injectable drug;
The medicine pen core, be positioned at this shell, inner several medicine injecting units that form a line of installing of this medicine pen core, connect with reverse wedge piece installing between these several medicine injecting units, the front end of these several medicine injecting units all has injection orifice, the injection orifice that wherein is positioned at this medicine pen core medicine injecting unit foremost communicates with this injection needle, be provided with the syringe pushing ram in the rear end of medicine pen core, be connected with the medicine injecting unit that is positioned at medicine pen core least significant end, by of the promotion of this syringe pushing ram to this medicine injecting unit of this medicine pen core least significant end, push those reverse wedge piece installings continuously and release with the medicine injecting unit that will finish injection, medicine injecting unit simultaneously that the next one is to be injected shift onto this medicine pen core foremost and its injection orifice communicate with this injection needle.
One embodiment of the bonded electric pulse gatherer of medical instruments according to the present invention, this device also comprises:
Tip protection spare is used for protecting this injection needle of this syringe needle group and this several electrodes to import syringe needle, and this Tip protection spare further comprises:
Protection pin medicated cap, the monomer pin medicated cap that the shape that imports syringe needle by several and this injection needle and this several electrodes is identical is integrated to be constituted, the arrangement mode of those monomer pin medicated caps is identical with the arrangement mode of each syringe needle in this syringe needle group, and this protection pin medicated cap and this syringe needle group be buckle closure mutually;
The protection needle guard covers the periphery that buckle closure has this syringe needle group of protection pin medicated cap.
One embodiment of the bonded electric pulse gatherer of medical instruments according to the present invention, this Tip protection spare, this slot electrode and this syringe needle group connect into medicated cap dress integral piece jointly, and this medicated cap dress integral piece is detachable being connected with the shell of this electric pulse gatherer.
One embodiment of the bonded electric pulse gatherer of medical instruments according to the present invention, this medicated cap dress integral piece is that spiral is connected with this shell.
One embodiment of the bonded electric pulse gatherer of medical instruments according to the present invention, after all medicine injecting units were finished injection in this medicine pen core, this medicated cap dress integral piece was removed so that the medicine pen core to be installed in this shell again.
One embodiment of the bonded electric pulse gatherer of medical instruments according to the present invention, the inner shell of these several medicine injecting units all has the soft draw-in groove with medicine injecting unit self identical length.
One embodiment of the bonded electric pulse gatherer of medical instruments according to the present invention, this reverse wedge piece installing is the parts that rubber is made.
The present invention contrasts prior art following beneficial effect: device of the present invention imports syringe needle by injection needle and the electrode that is installed in the device front end together, the target tissues such as electric pulse stimulation receptor muscle of having realized the medicine injection and having accompanied have with it strengthened therapeutic effect to promote carrying out synchronously of medicine importing.On the other hand, injection needle and electrode import syringe needle and all can shirk, and have held the medicine injecting unit of 1~10 independent packaging in the medicine pen core, can realize that single injectable drug pen core finishes the process of multiple injection.
Description of drawings
Fig. 1 is the structure chart of the embodiment of the bonded electric pulse gatherer of medical instruments of the present invention.
Fig. 2 is the sketch map of Tip protection spare and syringe needle group buckle closure.
Fig. 3 is the sketch map of medicine injecting unit.
Fig. 4 is the sketch map of syringe pushing ram.
Fig. 5 is the sketch map of medicine pen core.
The specific embodiment
The invention will be further described below in conjunction with drawings and Examples.
Fig. 1 shows the structure of the embodiment of the bonded electric pulse gatherer of medical instruments of the present invention.See also Fig. 1, the bonded electric pulse gatherer of the medical instruments of present embodiment comprises following parts: Tip protection spare 1, injection needle 2, electrode import syringe needle 3, slot electrode 4, medicine pen core 5, introducing apparatus shell 6.Wherein, Tip protection spare 1 belongs to selectable unit (SU).
Annexation between these parts is: slot electrode 4 is positioned on the pedestal of shell 6 front ends, and delivery outlet 9 electric connections by the outer electric pulse generator of electric conductance post 7 and device receive electric impulse signal.Injection needle 2 and a plurality of electrode import syringe needle 3 and form the syringe needle group together, and injection needle 2 is in the centre usually, and these electrodes import syringe needle 3 and distribute around injection needle 2.Injection needle 2 imports syringe needle 3 with electrode and all is connected with slot electrode 4.Medicine pen core 5 as shown in Figure 5 is positioned at shell 6, the a plurality of medicine injecting units 50 as shown in Figure 3 (being shown 4 in the drawings) that form a line are equipped with in inside, interconnect by reverse wedge piece installing 52 (for example being the parts that rubber is made) between these medicine injecting units 50.The front end of each medicine injecting unit 50 all has injection orifice, and the injection orifice that is positioned at medicine pen core medicine injecting unit 50 foremost communicates with injection needle 2.All there is the soft draw-in groove with medicine injecting unit self identical length at the inner shell place of medicine injecting unit 50.Be provided with as shown in Figure 4 syringe pushing ram 51 at the end of medicine pen core 5, be connected with the medicine injecting unit 50 that is positioned at medicine pen core least significant end.It is relations of buckle closure mutually that Tip protection spare 1 and injection needle 2 and electrode import syringe needle 3.
Please be simultaneously referring to Fig. 2, Tip protection spare 1 comprises two independently parts: protection pin medicated cap 100 and protection needle guard 102.Protection pin medicated cap 100 is consistent with the shape that these injection needles 2 and electrode import syringe needle 3; that is: the integral structure formed by several monomer pin medicated caps of protection pin medicated cap 100; wherein the arrangement mode of monomer pin medicated cap is identical with the arrangement mode of each syringe needle in the syringe needle group, and protection pin medicated cap 100 and syringe needle group be buckle closure mutually.Protection needle guard 102 the has covered buckle closure periphery of syringe needle group of protection pin medicated cap 102.In the present embodiment, Tip protection spare 1, slot electrode 4 and syringe needle group (comprising that injection needle 2 and electrode import syringe needle 3) connect into medicated cap dress integral piece jointly, and medicated cap dress integral piece is detachable being connected with the shell 6 of electric pulse gatherer, for example spiral connection.
During per injection, rely on the promotion of syringe pushing ram 51 to finish a shot, medicine injecting unit 50 moves forward through the promotion of syringe pushing ram 51, and the medicine in the medicine injecting unit 50 foremost enters human body by injection orifice and injection needle 2.In the process of carrying out the medicine injection by 2 pairs of human bodies of injection needle, electrode imports syringe needle 3 and also by the electric pulse of collecting electrode groove 4 conduction human body enforcement electric pulse is imported together.Thereby realized that target tissues such as the medicine injection and the electric pulse stimulation receptor muscle that accompanies with it promote to have strengthened therapeutic effect by carrying out synchronously of medicine importing.In addition, by the electric pulse generator of gatherer outside, can realize the adjustability and the controllability of leading-in technique parameters such as electric pulse waveform.After finishing a shot, earlier used medicated cap dress integral piece is taken off, continue pushing syringe pushing ram 51, treat originally to be in after foremost medicine injecting unit is pushed out and the medicine injecting unit 50 of back is pulled to the front end of medicine pen core 5, reinstall medicated cap dress integral piece once more, realize the injection and the importing of continuation, repeat said process, medicine injecting unit 50 in medicine pen core 5 is all released, and changes medicine pen core 5 again.
One aspect of the present invention imports syringe needle by injection needle and electrode and is set together, and has realized that medicine injection and the target tissues such as electric pulse stimulation receptor muscle that accompany with it promote carrying out synchronously in the medicine transfered cell, have alleviated patient's misery.The medicine pen core is disposable use, sealing and interchangeable on the other hand, and medicine injecting unit has wherein guaranteed the degree of accuracy of drug dose.
The foregoing description provides to those of ordinary skills and realizes or use of the present invention; those of ordinary skills can be under the situation that does not break away from invention thought of the present invention; the foregoing description is made various modifications or variation; thereby protection scope of the present invention do not limit by the foregoing description, and should be the maximum magnitude that meets the inventive features that claims mention.

Claims (7)

1. bonded electric pulse gatherer of medical instruments comprises:
Shell;
Slot electrode is positioned on the pedestal of this shell front end, and the electric pulse generator outer by electric conductance post and device is connected, and receives the electric impulse signal of electric pulse generator output;
The syringe needle group, be positioned at this shell foremost, several electrodes that comprise an injection needle and periphery import syringe needle, this injection needle and this several electrodes import syringe needle and all are connected with this slot electrode, wherein these several electrodes importing syringe needles receive by the electric pulse of this slot electrode conduction to go into to implement electric conductance, and this injection needle is used for injectable drug;
The medicine pen core, be positioned at this shell, inner several medicine injecting units that form a line of installing of this medicine pen core, connect with reverse wedge piece installing between these several medicine injecting units, the front end of these several medicine injecting units all has injection orifice, the injection orifice that wherein is positioned at this medicine pen core medicine injecting unit foremost communicates with this injection needle, be provided with the syringe pushing ram in the rear end of medicine pen core, be connected with the medicine injecting unit that is positioned at medicine pen core least significant end, by of the promotion of this syringe pushing ram to this medicine injecting unit of this medicine pen core least significant end, push those reverse wedge piece installings continuously and release with the medicine injecting unit that will finish injection, medicine injecting unit simultaneously that the next one is to be injected shift onto this medicine pen core foremost and its injection orifice communicate with this injection needle.
2. the bonded electric pulse gatherer of medical instruments according to claim 1 is characterized in that this device also comprises:
Tip protection spare is used for protecting this injection needle of this syringe needle group and this several electrodes to import syringe needle, and this Tip protection spare further comprises:
Protection pin medicated cap, the monomer pin medicated cap that the shape that imports syringe needle by several and this injection needle and this several electrodes is identical is integrated to be constituted, the arrangement mode of those monomer pin medicated caps is identical with the arrangement mode of each syringe needle in this syringe needle group, and this protection pin medicated cap and this syringe needle group be buckle closure mutually;
The protection needle guard covers the periphery that buckle closure has this syringe needle group of protection pin medicated cap.
3. the bonded electric pulse gatherer of medical instruments according to claim 2; it is characterized in that; this Tip protection spare, this slot electrode and this syringe needle group connect into medicated cap dress integral piece jointly, and this medicated cap dress integral piece is detachable being connected with the shell of this electric pulse gatherer.
4. the bonded electric pulse gatherer of medical instruments according to claim 3 is characterized in that, this medicated cap dress integral piece is that spiral is connected with this shell.
5. the bonded electric pulse gatherer of medical instruments according to claim 3 is characterized in that, after all medicine injecting units were finished injection in this medicine pen core, this medicated cap dress integral piece was removed so that the medicine pen core to be installed in this shell again.
6. the bonded electric pulse gatherer of medical instruments according to claim 1 is characterized in that the inner shell of these several medicine injecting units all has the soft draw-in groove with medicine injecting unit self identical length.
7. the bonded electric pulse gatherer of medical instruments according to claim 1 is characterized in that, this reverse wedge piece installing is the parts that rubber is made.
CN2010101392806A 2010-04-06 2010-04-06 Medical instrument-combined electric pulse introduction device Active CN101804224B (en)

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CN2010101392806A CN101804224B (en) 2010-04-06 2010-04-06 Medical instrument-combined electric pulse introduction device

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Application Number Priority Date Filing Date Title
CN2010101392806A CN101804224B (en) 2010-04-06 2010-04-06 Medical instrument-combined electric pulse introduction device

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CN101804224B CN101804224B (en) 2011-11-30

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113633852A (en) * 2015-12-28 2021-11-12 因诺维奥制药公司 Intradermal jet injection electroporation device
RU2805271C2 (en) * 2021-11-10 2023-10-13 Евгений Александрович Горемыкин System for restoration of quadripedal animals after spinal injuries

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020065481A1 (en) * 2000-11-24 2002-05-30 Ckm Diagnostics, Inc. Nerve stimulator output control needle with depth determination capability and method of use
WO2003075978A2 (en) * 2002-03-07 2003-09-18 Merck & Co., Inc. Clinical syringe with electrical stimulation aspects
CN1678369A (en) * 2002-07-04 2005-10-05 伊诺维奥公司 Electro-perforation device and injection apparatus
CN101001665A (en) * 2004-06-24 2007-07-18 斯菲尔根公司 Device for transferring molecules to cells using an electric force
CN101342390A (en) * 2007-07-10 2009-01-14 上海塔瑞莎健康科技有限公司 Electroporation leading-in apparatus for medicament

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020065481A1 (en) * 2000-11-24 2002-05-30 Ckm Diagnostics, Inc. Nerve stimulator output control needle with depth determination capability and method of use
WO2003075978A2 (en) * 2002-03-07 2003-09-18 Merck & Co., Inc. Clinical syringe with electrical stimulation aspects
US20050154434A1 (en) * 2002-03-07 2005-07-14 Adam Simon Clinical syringe with electrical stimulation aspects
CN1678369A (en) * 2002-07-04 2005-10-05 伊诺维奥公司 Electro-perforation device and injection apparatus
CN101001665A (en) * 2004-06-24 2007-07-18 斯菲尔根公司 Device for transferring molecules to cells using an electric force
CN101342390A (en) * 2007-07-10 2009-01-14 上海塔瑞莎健康科技有限公司 Electroporation leading-in apparatus for medicament

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113633852A (en) * 2015-12-28 2021-11-12 因诺维奥制药公司 Intradermal jet injection electroporation device
CN113633852B (en) * 2015-12-28 2023-09-29 因诺维奥制药公司 Intradermal jet injection electroporation device
RU2805271C2 (en) * 2021-11-10 2023-10-13 Евгений Александрович Горемыкин System for restoration of quadripedal animals after spinal injuries

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