CN102416208B - Portable automatic electric shock continuous injector - Google Patents
Portable automatic electric shock continuous injector Download PDFInfo
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- CN102416208B CN102416208B CN 201110232582 CN201110232582A CN102416208B CN 102416208 B CN102416208 B CN 102416208B CN 201110232582 CN201110232582 CN 201110232582 CN 201110232582 A CN201110232582 A CN 201110232582A CN 102416208 B CN102416208 B CN 102416208B
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Abstract
The invention relates to a portable automatic electric shock continuous injector, which is characterized by comprising a handle, wherein an electric shock circuit is arranged in the handle; a convex pillar at the front end of the handle is provided with a locking nut, the locking nut is connected with an injection tube shell, the other end of the injection tube shell is fixedly connected with a splitter shell, and a glass injection tube and a four-needle joint are arranged in the injection tube shell; the injection tube is connected with a splitter positioned in the splitter shell through a three-way valve, a joint at the end part of the splitter is connected to the splitter shell, and the joint is connected with a double-needle head; a third vent of the three-way valve is connected with a liquid sucking joint, and two vents leading to the liquid sucking joint of the splitter of the three-way valve are respectively provided with a check valve; and the rear end of the handle is provided with a pressing switch hinged with the handle, the middle part of the pressing switch is spherically connected with a piston rod penetrated in the injection tube in a sealing mode, and a hinge point of the pressing switch and the handle is provided with a reset spring. The portable automatic electric shock continuous injector disclosed by the invention can simultaneously realize injection and electric shock, has a plurality of integrated functions, and can be widely used in an inoculation process of various organisms except the human body.
Description
Technical field
The present invention relates to a kind of syringe, particularly about a kind of Portable automatic electric shock continuous injector for the importing of DNA plasmid muscle.
Background technology
Because dna vaccination is easier to design construction, production, storage and transportation than traditional vaccine, so can expecting to substitute traditional viral vaccine, dna immunization resists the epidemic situation that frequently occurs.The process that electric shock occurs refers to that when of short duration controlled electric pulse stimulation arrived target muscular tissue, surface of cell membrane can form a lot of micropores.This is so that be convenient to enter cell such as the such macromole of DNA, expresses thereby enter in the nucleus beginning antigen protein.This effective DNA introduction method can be strengthened Cell uptake DNA and immunoreation.Compare with simple DNA intramuscular injection, use the effect of dna vaccination more obvious by electric shock.Such one be based upon take electric shock as basic comprehensive DNA introducing apparatus once use in simultaneously DNA injection and moment (less than 1 second) produce on the electric pulse basis, this so that DNA import more effective with can repeat.
There is document to show that electric shock can strengthen the immunoreation of HBV dna vaccination, can uses the TriGrid of Ichor company
TMThe electric shock technology imports the DNA medicine.This TriGrid
TMThe electric shock test that muscle imports is comprised of four electrodes, uses central syringe needle separately to import the DNA medicine.This device links to each other with pulse generator by electric wire, because electric shock device (instrument) needs electric energy, provides so it need to be communicated with external power supply by electric wire, and such connected mode has limited the range of activity of user.Past report uses disposable syringe and the syringe needle of processing material to carry out the DNA importing according to this, can avoid spreading disease, and is applicable to human or groupuscule and uses.Uninject
TM(disposable Pre-filled syringe) is a kind of little syringe of pre-filled, single dose, and it is designed to disposable use, thus its to be used for veterinary's immunity just inconvenient.Being used in several hours, to inject several thousand parts of vaccines in the veterinary drug situation, therefore use continuous injector just to become unique method.Yet injection process is repetition, and particularly when using syringe and two devices of electric shock, the electric pulse number of times that this device carries out can not be monitored.Therefore, dna vaccination uses and is not easy to record.
Summary of the invention
For the problems referred to above, the purpose of this invention is to provide a kind of simple to operation, Portable automatic electric shock continuous injector of satisfying a large amount of requirements of using in the short time that has simultaneously injection and two effects that shock by electricity.
For achieving the above object, the present invention takes following technical scheme: a kind of Portable automatic electric shock continuous injector is characterized in that: it comprises one handle, is provided with an electric-shocking circuit in the described handle; One locking nut is set on the projection of described handle front end, and described locking nut connects a syringe shell, and the other end of described syringe shell is fixedly connected with a diverter shell, is provided with a glass syringe and one or four needle adapters in the described syringe shell; Described syringe connects a diverter that is positioned at described diverter shell by a three-way valve, and the joint of described diverter end is connected on the described diverter shell, connects a double needle on the described joint; The 3rd port of described three-way valve connects an imbibition joint, and two passage ports that described three-way valve leads to described diverter imbibition joint all are provided with a check valve; The rear end of described handle is provided with a push switch hinged with it, and described push switch middle part ball connects a sealing and wears the piston rod of penetrating in syringe, and the hinged place of described push switch and described handle is provided with back-moving spring.
Described electric-shocking circuit comprises a rechargeable battery, a capacitor, a controller, a liquid crystal display and an electric shock control loop, described controller, liquid crystal display and electric shock control loop interconnect by wire, and described capacitor electrode connects described electric shock control loop; Described controller is electrically connected two joints of described four needle adapter afterbodys, two joints of described four needle adapter heads are electrically connected described electric shock control loop, the positive and negative electrode of described electric shock control loop connects two electrode T-Rings that arrange in the described joint by wire, and each described electrode T-Ring is electrically connected a syringe needle afterbody in the described double needle; Described controller is controlled described capacitor charging/discharging by described electric shock control loop, and shows number of shocks at described liquid crystal display; Described rechargeable battery is connected with external power source by power interface, is each parts power supply.
Be provided with sensor between described piston rod or push switch and the described controller, the discharge and the liquid infusion that are used for coordination electric shock control loop are synchronous.
Connect light emitting diode and the buzzer that is used for acousto-optic hint in the described electric shock control loop.
A kind of Portable automatic electric shock continuous injector is characterized in that: it comprises injecting cavity and electronics chamber, is respectively arranged with mutual grafting all-in-one-piece on described injecting cavity and the electronics chamber and stretches out foot and chute; Described injecting cavity comprises one handle, and described handle rear end arranges a push switch, and described push switch bottom is hinged with described handle, and the hinged place is provided with a back-moving spring that stretches into respectively in described handle and the push switch; The described handle top dosage that is threaded is regulated screwed pipe, and described dosage is regulated in the screwed pipe and worn a piston rod, and the afterbody ball of described piston rod is connected on the top of described push switch, and described piston rod middle part has a circle and is used for regulating the protruding sour jujube of injected dose; Described handle front end is fixedly connected with a syringe shell, the other end of described syringe shell is fixedly connected with a diverter shell, be provided with a glass syringe in the described syringe shell, the head seal of described piston rod is plugged in the described glass syringe, described glass syringe connects a diverter by a three-way valve, the joint of described diverter end is connected on the described diverter shell, connect a double needle on the described joint, each outlet in two outlets of described diverter is communicated with a syringe needle in the described double needle; The 3rd port of described three-way valve connects an imbibition joint, and two passage ports that described three-way valve leads to described diverter and imbibition joint all are provided with a check valve;
Described electronics chamber comprises an electronics chamber enclosure, in the described electronics chamber enclosure rechargeable battery is set, a capacitor, a controller, electric shock control loop and a liquid crystal display; Described controller, liquid crystal display and electric shock control loop interconnect by wire, described capacitor electrode connects described electric shock control loop, the positive and negative electrode of described electric shock control loop is electrically connected two electrode T-Rings that arrange in the described joint, and each described electrode T-Ring is electrically connected a syringe needle afterbody in the described double needle; Described controller is controlled described capacitor charging/discharging by described electric shock control loop, and shows number of shocks at described liquid crystal display; Described rechargeable battery is connected with external power source by power interface, is each parts power supply.
Be provided with sensor between described piston rod or push switch and the described controller, the discharge and the liquid infusion that are used for coordination electric shock control loop are synchronous.
Connect light emitting diode and the buzzer that is used for acousto-optic hint in the described electric shock control loop.
The present invention is owing to take above technical scheme, it has the following advantages: 1, the present invention is owing to be provided with the double needle that imports the DNA medicine in instrument, this double needle can be used as simultaneously two electrodes that produce electric pulse and uses, and therefore can realize simultaneously injection and two effects that shock by electricity.2, the present invention is owing to insert chargeable battery in instrument, this battery can provide the electric energy that is enough to surpass 1000 electric shocks, has therefore saved the electric wire that connects external power supply, and is not only easy to carry, and the fast changeable battery, can deal with more vaccine injection requirement.3, the present invention is used for showing injection and the number of times that shocks by electricity owing to disposed the display screen of four figures, so user can be understood the number of shocks of frequency injection and initiation at any time.4, the present invention is owing to be provided with buzzer and LED light, although therefore need through charging interval several seconds before each electric shock, user can according to the prompting of sound and light program, can both provide suitable electric shock condition when guaranteeing per injection.5, the present invention can mount and dismount easily, automatically produces the work that electric pulse is finished the electric shock vaccinate with hands once pushing away gently, and is easy to operate, and can produce stable and consistent electric current in the injection site, from different muscle conditional independence.The present invention integrates several functions, can be widely used in the inoculation process of the various biologies except human body.
Description of drawings
Fig. 1 is structural representation of the present invention
Fig. 2 is joint of the present invention and double needle connection diagram
Fig. 3 is another embodiment of the present invention
Fig. 4 is that Fig. 3 decomposes the rear lower structural representation
Fig. 5 is that Fig. 3 decomposes the upper back structural representation
The specific embodiment
Below in conjunction with drawings and Examples the present invention is described in detail.
Embodiment 1:
As shown in Figure 1, present embodiment comprises one handle 1, is provided with an electric-shocking circuit in the handle 1, and electric-shocking circuit comprises a rechargeable battery 2, a capacitor 3, a controller 4, a liquid crystal display 5 and an electric shock control loop 6.Controller 4, liquid crystal display 5 and electric shock control loop 6 interconnect by wire, capacitor 3 connects electric shock control loop 6 by wire, controller 4 is by electric shock control loop 6 control capacitors 3 discharging current when shocking by electricity, be its charging after the electric shock, and show number of shocks at liquid crystal display 5.Rechargeable battery 2 connects capacitor 3, controller 4, liquid crystal display 5 and electric shock control loop 6 by wire, so that power supply to be provided; Rechargeable battery 2 is connected charging by the power interface (not shown) with external power source.
As shown in Figure 1 and Figure 2, projection at the front end of handle 1 arranges a locking nut 7, connect a syringe shell 8 at locking nut 7 other ends, be fixedly connected with a diverter shell 9 at the other end of syringe shell 8, be provided with a glass syringe 10 and one or four needle adapters 11 in the syringe shell 8.Syringe 10 connects a diverter 13 that is positioned at diverter shell 9 by a three-way valve 12, and the joint 14 of diverter 13 ends is connected on the diverter shell 9, at joint 14 connections one double needle 15.The 3rd port of three-way valve 12 connects an imbibition joint 16, and imbibition joint 16 is used for connecting the injection medicinal liquid, and two passage ports that three-way valve 12 connects diverter 13 and imbibition joint 16 all are provided with a check valve 17, to prevent liquid return.Two joints of four needle adapters, 11 afterbodys are by wire connection controller 4, two joints of four needle adapters, 11 heads connect electric shock control loop 6 by wire, by two electrode T-Ring (not shown)s of wire jointing 14 interior settings, each electrode T-Ring is electrically connected a syringe needle afterbody in the double needle 15 to the positive and negative electrode of electric shock control loop 6 respectively.The rear end of handle 1 is provided with a push switch 19, the bottom of push switch 19 and handle 1 are hinged, the middle part ball of push switch 19 connects a sealing and wears the piston rod 20 of penetrating in syringe 9, hinged place at push switch 19 and handle 1 is provided with the back-moving spring (not shown), after unclamping push switch 19, it can drive piston rod 20 automatic retractions.
Embodiment 2:
Shown in Fig. 3～5, present embodiment is divided into the injecting cavity 30 of bottom and electronics chamber 50 two parts on top with whole injection device, be respectively arranged with the all-in-one-piece of mutually to peg graft on two parts and stretch out foot and chute, stretching out arranging of foot and chute can be as required and processing technology, adopt various structures, do not repeat them here.
As shown in Figure 3, the injecting cavity 30 of present embodiment comprises one handle 31, and handle 31 rear ends arrange a push switch 32, and push switch 32 bottoms and handle 31 are hinged.The hinged place is provided with a back-moving spring 33 that stretches into respectively in handle 31 and the push switch 32.The top of handle 31 is threaded connection a dosage and regulates screwed pipe 34, dosage is regulated in the screwed pipe 34 and is equipped with a piston rod 35, the afterbody ball of piston rod 35 is connected on the top of push switch 32, piston rod 35 middle parts have the protruding sour jujube 36 of a circle, dosage is regulated the position that screwed pipe 34 can be regulated protruding sour jujube 36 relative handles 31, and then the stroke of regulating piston bar 35, namely regulate injected dose.Handle 31 front ends are fixedly connected with a syringe shell 37, the other end of syringe shell 37 is fixedly connected with a diverter shell 38, be provided with a glass syringe 39 in the syringe shell 37, the head seal of piston rod 35 is plugged in the glass syringe 39, glass syringe 39 connects a diverter 41 by a three-way valve 40, the joint 42 of diverter 41 ends is connected on the diverter shell 38, connect a double needle 43 on the joint 42, each outlet in two outlets of diverter 41 is communicated with a syringe needle in the double needle 43.The 3rd port of three-way valve 40 connects an imbibition joint 44, and imbibition joint 44 is used for connecting injection liquid, and two passage ports that three-way valve 40 leads to diverter 41 and imbibition joint 44 all are provided with a check valve 45, to prevent liquid return.
As shown in Figure 4, the electronics chamber 50 of present embodiment comprises an electronics chamber enclosure 51, electronics chamber enclosure 51 an interior rechargeable battery 52, one capacitors 53, one controllers 54, electric shock control loop 55 and the liquid crystal displays 56 of arranging.Controller 54, liquid crystal display 55 and electric shock control loop 56 interconnect by wire, capacitor 53 connects electric shock control loop 56 by wire, the positive and negative electrode of electric shock control loop 56 is by two electrode T-Ring (not shown)s of wire jointing 44 interior settings, and each electrode T-Ring is electrically connected a syringe needle afterbody in the double needle 43.Discharging current when controller 54 shocks by electricity by electric shock control loop 55 control capacitors 53 is its charging after the electric shock, and shows number of shocks at liquid crystal display 55.Rechargeable battery 52 connects capacitor 53, controller 54, liquid crystal display 55 and electric shock control loop 56 by wire, so that power supply to be provided; Rechargeable battery 52 is connected charging by the power interface (not shown) with external power source.
In the various embodiments described above, after guaranteeing that the present invention starts, the operator can understand from liquid crystal display the parameters such as power supply status, injection and number of shocks, and liquid crystal display shows just that behind equipment power-on the enumerator on the liquid crystal display can make zero by button.
In the various embodiments described above, in order to guarantee the operation of when carrying out drug injection, shocking by electricity, can between piston rod or push switch and controller, the sensor (not shown) be set, synchronous with discharge and the liquid infusion of coordinating the electric shock control loop.Can realize electric shock when guaranteeing per injection, can in the electric shock control loop, connect the light emitting diode 57 that to see from the outside and to hear and the acousto-optic hint of buzzer 58 (as shown in Figure 4), with the charging of electrolysis condenser 53 whether finish the electric shock state of preparing that is in, after per injection and electric shock are finished, the counter values in the liquid crystal display all will increase automatically.Wherein, controller of the present invention and electric shock control loop can adopt circuit of the prior art, as long as can realize electric shock function.
As shown in Figure 5, the below is take embodiment 2 as example, and the operating process when being applied to the dna vaccination liquid medicine injection in the animal body to the present invention is described below:
1) imbibition joint 44 is opened the on and off switch that arranges on the electronics chamber 50 by a hose connection medical liquid container, checks the parameters that display shows, and enumerator is made zero;
2) hold handle 31, thumb promotes forward push switch 32, drive piston rod 35 air in the syringe 39 is released double needle 43, then unclamp thumb, back-moving spring 32 is return push switch 32, because do not have conductor between two syringe needles 43 this moment, therefore can not shock by electricity, simultaneously because the effect of two check valves 45, air can not return syringe 39, and medicinal liquid enters syringe 39 along the flexible pipe imbibition joint 44 of flowing through; Repeated presses repeatedly until from double needle 43 ejection medicinal liquids, then shows in the system emptying air like this.
3) double needle 43 is inserted in the animal body, again promote forward push switch 32 with thumb, drive piston rod 35 medicinal liquid in the syringe 39 is pushed receptor, meanwhile, two syringe needles 43 have been communicated with the loop that is comprised of two electrode T-Rings, electric shock control loop 56 and capacitor 53 take receptor as conductor, the a very short time of finishing vaccine injection that, the 100V/cm electric field just produces around the syringe needle, namely finishing once electric shock operation when finishing vaccine injection.
The various embodiments described above only are used for explanation the present invention, and wherein the structure of each parts, connected mode and operational approach etc. all can change to some extent.Every equivalents and improvement of carrying out on the basis of technical solution of the present invention all should do not got rid of outside protection scope of the present invention.
Claims (6)
1. Portable automatic electric shock continuous injector, it is characterized in that: it comprises one handle, is provided with an electric-shocking circuit in the described handle; One locking nut is set on the projection of described handle front end, and described locking nut connects a syringe shell, and the other end of described syringe shell is fixedly connected with a diverter shell, is provided with a glass syringe and one or four needle adapters in the described syringe shell; Described syringe connects a diverter that is positioned at described diverter shell by a three-way valve, and the joint of described diverter end is connected on the described diverter shell, connects a double needle on the described joint; The 3rd port of described three-way valve connects an imbibition joint, and two passage ports that described three-way valve leads to described diverter, described imbibition joint all are provided with a check valve;
The rear end of described handle is provided with a push switch hinged with it, and described push switch middle part ball connects a sealing and is located in the interior piston rod of syringe, and the hinged place of described push switch and described handle is provided with back-moving spring;
Described electric-shocking circuit comprises a rechargeable battery, a capacitor, a controller, a liquid crystal display and an electric shock control loop, described controller, liquid crystal display and electric shock control loop interconnect by wire, and described capacitor electrode connects described electric shock control loop; Described controller is electrically connected two joints of described four needle adapter afterbodys, two joints of described four needle adapter heads are electrically connected described electric shock control loop, the positive and negative electrode of described electric shock control loop connects two electrode T-Rings that arrange in the described joint by wire, and each described electrode T-Ring is electrically connected a syringe needle afterbody in the described double needle; Described controller is controlled described capacitor charging/discharging by described electric shock control loop, and shows number of shocks at described liquid crystal display; Described rechargeable battery is connected with external power source by power interface, is each parts power supply.
2. a kind of Portable automatic electric shock continuous injector as claimed in claim 1 is characterized in that: be provided with sensor between described piston rod or push switch and the described controller, the discharge and the liquid infusion that are used for coordinating the electric shock control loop are synchronous.
3. a kind of Portable automatic electric shock continuous injector as claimed in claim 1 or 2 is characterized in that: connect light emitting diode and the buzzer that is used for acousto-optic hint in the described electric shock control loop.
4. Portable automatic electric shock continuous injector, it is characterized in that: it comprises injecting cavity and electronics chamber, is respectively arranged with mutual grafting all-in-one-piece on described injecting cavity and the electronics chamber and stretches out foot and chute;
Described injecting cavity comprises one handle, and described handle rear end arranges a push switch, and described push switch bottom is hinged with described handle, and the hinged place is provided with a back-moving spring that stretches into respectively in described handle and the push switch; The described handle top dosage that is threaded is regulated screwed pipe, and described dosage is regulated in the screwed pipe and worn a piston rod, and the afterbody ball of described piston rod is connected on the top of described push switch, and described piston rod middle part has a circle and is used for regulating the protruding sour jujube of injected dose; Described handle front end is fixedly connected with a syringe shell, the other end of described syringe shell is fixedly connected with a diverter shell, be provided with a glass syringe in the described syringe shell, the head seal of described piston rod is plugged in the described glass syringe, described glass syringe connects a diverter by a three-way valve, the joint of described diverter end is connected on the described diverter shell, connect a double needle on the described joint, each outlet in two outlets of described diverter is communicated with a syringe needle in the described double needle; The 3rd port of described three-way valve connects an imbibition joint, and two passage ports that described three-way valve leads to described diverter and imbibition joint all are provided with a check valve;
Described electronics chamber comprises an electronics chamber enclosure, in the described electronics chamber enclosure rechargeable battery is set, a capacitor, a controller, electric shock control loop and a liquid crystal display; Described controller, liquid crystal display and electric shock control loop interconnect by wire, described capacitor electrode connects described electric shock control loop, the positive and negative electrode of described electric shock control loop is electrically connected two electrode T-Rings that arrange in the described joint, and each described electrode T-Ring is electrically connected a syringe needle afterbody in the described double needle; Described controller is controlled described capacitor charging/discharging by described electric shock control loop, and shows number of shocks at described liquid crystal display; Described rechargeable battery is connected with external power source by power interface, is each parts power supply.
5. a kind of Portable automatic electric shock continuous injector as claimed in claim 4 is characterized in that: be provided with sensor between described piston rod or push switch and the described controller, the discharge and the liquid infusion that are used for coordinating the electric shock control loop are synchronous.
6. such as claim 4 or 5 described a kind of Portable automatic electric shock continuous injectors, it is characterized in that: connect light emitting diode and the buzzer that is used for acousto-optic hint in the described electric shock control loop.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110232582 CN102416208B (en) | 2011-08-15 | 2011-08-15 | Portable automatic electric shock continuous injector |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110232582 CN102416208B (en) | 2011-08-15 | 2011-08-15 | Portable automatic electric shock continuous injector |
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| CN102416208A CN102416208A (en) | 2012-04-18 |
| CN102416208B true CN102416208B (en) | 2013-05-29 |
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| CN 201110232582 Active CN102416208B (en) | 2011-08-15 | 2011-08-15 | Portable automatic electric shock continuous injector |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108392696A (en) * | 2018-04-09 | 2018-08-14 | 哈工大机器人（合肥）国际创新研究院 | A kind of continous way injection device |
| CN111840750B (en) * | 2020-07-27 | 2022-07-08 | 四川大学华西医院 | PICC automatic pigging device |
| CN113274116B (en) * | 2021-05-12 | 2024-05-14 | 普亚生物科技有限公司 | Full-automatic electroporation syringe |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN86107741A (en) * | 1986-11-20 | 1988-06-01 | 图布信巴图 | Continuous injector for domestic animals |
| US5176645A (en) * | 1991-05-01 | 1993-01-05 | Diana Corporation | Pneumatic, modular device for dispensing medication to animals |
| CN201085825Y (en) * | 2007-03-26 | 2008-07-16 | 郭爱清 | Medical electric medicine adding apparatus |
| CN201596185U (en) * | 2009-12-09 | 2010-10-06 | 王峻 | Full automatic insulin injection aid |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN202198921U (en) * | 2011-08-15 | 2012-04-25 | 格兰柏生化科技有限公司 | Portable device with effects of automatic electric shock and continuous injection |
-
2011
- 2011-08-15 CN CN 201110232582 patent/CN102416208B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN86107741A (en) * | 1986-11-20 | 1988-06-01 | 图布信巴图 | Continuous injector for domestic animals |
| US5176645A (en) * | 1991-05-01 | 1993-01-05 | Diana Corporation | Pneumatic, modular device for dispensing medication to animals |
| CN201085825Y (en) * | 2007-03-26 | 2008-07-16 | 郭爱清 | Medical electric medicine adding apparatus |
| CN201596185U (en) * | 2009-12-09 | 2010-10-06 | 王峻 | Full automatic insulin injection aid |
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| CN102416208A (en) | 2012-04-18 |
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