CN101797257A - Hormone preparation for sow aphrodisiac - Google Patents
Hormone preparation for sow aphrodisiac Download PDFInfo
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- CN101797257A CN101797257A CN201010023023A CN201010023023A CN101797257A CN 101797257 A CN101797257 A CN 101797257A CN 201010023023 A CN201010023023 A CN 201010023023A CN 201010023023 A CN201010023023 A CN 201010023023A CN 101797257 A CN101797257 A CN 101797257A
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Abstract
The invention relates to a hormone spray agent for sow aphrodisiac, which comprises the following components in percentage by weight: 0.001-0.006% of swine ectohormone, 0-5% of cosolvent and balance of a water solution containing 55-85% of ethanol, wherein the swine ectohormone is androst-16-ene-3 alpha-ol or androst-16-ene-3-one. The spray agent of the invention has simple manufacturing, can effectively improve the reproductive capacity of a sow, and promotes the development of livestock breeding.
Description
Technical field
The present invention relates to a kind of sow with functions of promoting sexual maturity hormone spray, be a kind of pig ectohormone that contains 0.001～0.006% weight, 0～5% weight cosolvent, all the other are for containing 55～85% alcoholic acid aqueous solutions.This spray is made simple, transportation and safe and convenient to use, and cost is low, can effectively promote oestrus of sow, improves the fertility of sow, promotes the development of aquaculture.
Technical background
China's pig industry relied on the domestic behindhand type of peasant household in the past to a great extent, the easy like this cut of pork anxiety that causes, and rise in price, so we need set up intensification, large-scale pig cultivation base.The intensive pig production benefit just depends on the fertility of sow. be every sow is produced tire number and every tire litter size per year.Every sow produce the tire number per year and every tire litter size not only closely related with their state of oestrusing, also can accurately grasp their oestrus relevant with the breed personnel.Therefore, the state of oestrusing of sow and replacement gilt and breed personnel accurately grasp the key that oestrusing of sow and replacement gilt becomes the intensive pig production economic benefit.In order to guarantee and to have improved every sow and produced tire number and every tire litter size per year, some measures have been adopted on the pig farm at present, enclose together as the boar and the sow that regularly allow the branch circle raise, utilize the abnormal smells from the patient of boar to induce oestrus of sow, spray boar urine (wherein containing the outer sex pheromone of pig) and induce oestrus of sow, or the injectivity hormonal medicaments promotes oestrus of sow.The former belongs to raiser's empirical measure, and is for peasant household raises pigs, simple to operate.But raise pigs for scale, lack standard operation, random big.The latter adopts the hormonal medicaments injection, the cost height, and inconvenient operation, also having simultaneously increases the undesirable element that influences the meat products safety.In any case, utilize abnormal smells from the patient of boar or sprinkling boar urine can induce the principles of science of oestrus of sow clear after deliberation.The outer sex pheromone of pig that exists in abnormal smells from the patient of boar or the sprinkling boar urine is the material base that they can induce oestrus of sow, and the main chemical compositions of the outer sex pheromone of pig is androstane-16-alkene-3 α-pure and mild rost-16-en-3-one.Though it is very difficult directly to obtain the outer sex pheromone of natural pig, the chemist can synthetic and the outer on all four androstane of sex pheromone effect of natural pig-16-alkene-3 α-pure and mild rost-16-en-3-one.
In view of domestic hysteresis, influenced of the application of this advanced technology in China in this area research work.As far back as the eighties in last century, China's chemist has also carried out the study on the synthesis of the outer sex pheromone androstanes of some pigs-16-alkene-3 α-pure and mild rost-16-en-3-one, its synthesis strategy and method and similar abroad.Because the external product price is higher, domestic shortages be unique, reason such as synthetic technology efficiently, with cause pig outward sex pheromone Nobody Knows so far in China's pig industry.Tian Weisheng group utilizes China's agricultural wastes (sisalagenin in the Folium Agaves Sisalanae system fiber crops waste residue) outer sex pheromone androstane of synthetic pig-16-alkene-3 α-pure and mild rost-16-en-3-one (Chinese patent CN200710037402.9), not only can improve the added value of Folium Agaves Sisalanae plantation industry, reduce the garbage of the contaminated environment of its generation, benefit Folium Agaves Sisalanae and plant regional peasant, can reduce the synthetic cost (wishing its cost of control 20-50% of product abroad) of the outer sex pheromone androstane of pig-16-alkene-3 α-pure and mild rost-16-en-3-one again, adopt novel forms such as spray to replace the aerosol dosage forms of external like product simultaneously, make the transportation of the outer sex pheromone of pig, use safe ready more, cost further reduces.Thereby solve the crucial scientific and technological problem that intensive pig production already exists, promote that large scale of pig farm already develops, ensure people's quality of life.
Summary of the invention
The purpose of this invention is to provide a kind of novel sow with functions of promoting sexual maturity hormone preparation.
Sow with functions of promoting sexual maturity hormone preparation provided by the invention is a kind of pig ectohormone of 0.001～0.006% weight, cosolvent of 0～5% weight of containing, and all the other are for containing 55～85% alcoholic acid aqueous solutions; Employing contains the pig ectohormone solution of more multiple amount, also is fine but causes the waste of pig ectohormone; Described cosolvent is dimethyl sulfoxide (DMSO) or N, dinethylformamide (DMF).
Sow with functions of promoting sexual maturity hormone preparation composition of the present invention is recommended as the pig ectohormone that contains 0.002～0.004% weight, and all the other are for containing the alcoholic acid aqueous solution of 68～75% weight.
Can make spray in the above-mentioned preparation uses.
Wherein, pig ectohormone is androstane-16-alkene-3 α-alcohol or rost-16-en-3-one, and structure is:
Wherein,
Sow with functions of promoting sexual maturity hormone preparation provided by the invention is through experiment and induce the oestrus of sow difference on effect little with boar, applicable to the unified usefulness that lures feelings for sow in the smart geographic pig farm.
The present invention has following advantage:
1. the manufacture method of preparation is simple and convenient, and cost is low,
2. adopt novel form such as spray to replace the aerosol dosage forms of external like product, make the outer sex pheromone of pig transportation, use safe ready more, cost further reduces.
Specific implementation method
To help to understand the present invention by following specific implementation method, but not limit content of the present invention.
The preparation reference literature (Chinese patent CN200710037402.9) of raw material rost-16-en-3-one and androstane-16-alkene-3 α-alcohol.
Embodiment 1
In the 100ml spray bottle, add the rost-16-en-3-one of 3mg, 69g ethanol, 30g water, mixing uses.142 of the multiparity sows that selection is weaned on the same day, by gestational age, the body fat all is divided into experimental group and matched group at random, experimental group is on every day, afternoon, each once used the sow with functions of promoting sexual maturity hormone preparation, matched group is on every day, and afternoon, each once used boar to lure feelings, accomplishes two groups of position limiting fences interference effect not mutually separated by a distance; Totally 50 days, experimental group was oestrused 62 as a result, the rate 87% of oestrusing, and matched group is oestrused 58, and the rate of oestrusing is 82%.The experimental group rate of oestrusing wants high; Test-tube non-return rate after oestrusing, the conception rate that experimental group is 62 is 97%, the conception rate that matched group is 58 is 98%.
Embodiment 2
In the 100ml spray bottle, add androstane-16-alkene-3 α-alcohol of 3mg, 69g ethanol, 30g water, mixing uses.148 of the multiparity sows that selection is weaned on the same day, by gestational age, the body fat all is divided into experimental group and matched group at random, experimental group is on every day, afternoon, each once used the sow with functions of promoting sexual maturity hormone preparation, matched group is on every day, and afternoon, each once used boar to lure feelings, accomplishes two groups of position limiting fences interference effect not mutually separated by a distance; Totally 60 days, experimental group was oestrused 68 as a result, the rate 91% of oestrusing, and matched group is oestrused 70, and the rate of oestrusing is 93%.The experimental group rate of oestrusing wants high; Test-tube non-return rate after oestrusing, the conception rate that experimental group is 68 is 88%, the conception rate that matched group is 70 is 93%.
Embodiment 3
In the 100ml spray bottle, add the rost-16-en-3-one of 2mg, 56g ethanol, 40g water, the 3g dimethyl sulfoxide, mixing uses.
Embodiment 4
In the 100ml spray bottle, add androstane-16-alkene-3 α-alcohol of 4mg, 84g ethanol, 15g water, mixing uses.
Embodiment 5
In the 100ml spray bottle, add the rost-16-en-3-one of 3mg, 76g ethanol, 20g water, 3gN, dinethylformamide, mixing uses.
Claims (3)
1. sow with functions of promoting sexual maturity hormone preparation, it is characterized in that a kind of pig ectohormone that contains 0.001～0.006% weight, 0～5% weight cosolvent, all the other are for containing 55～85% alcoholic acid aqueous solutions; Described cosolvent is dimethyl sulfoxide or N, dinethylformamide; Described pig ectohormone is androstane-16-alkene-3 α-alcohol or rost-16-en-3-one.
2. preparation as claimed in claim 1 is characterized in that described preparation is the pig ectohormone that contains 0.002～0.004% weight, and all the other are for containing the alcoholic acid aqueous solution of 68～75% weight.
3. preparation as claimed in claim 1 or 2 is characterized in that described preparation is a spray.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010023023A CN101797257A (en) | 2010-01-20 | 2010-01-20 | Hormone preparation for sow aphrodisiac |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010023023A CN101797257A (en) | 2010-01-20 | 2010-01-20 | Hormone preparation for sow aphrodisiac |
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| CN101797257A true CN101797257A (en) | 2010-08-11 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201010023023A Pending CN101797257A (en) | 2010-01-20 | 2010-01-20 | Hormone preparation for sow aphrodisiac |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2757888A4 (en) * | 2011-09-20 | 2015-03-18 | Sergeants Pet Care Prod Inc | Interomone compositions and their use to modify behavior in different vertebrate species |
| US9480688B2 (en) | 2011-09-20 | 2016-11-01 | Sergeant's Pet Care Products, Inc. | Pheromone compositions and their use to modify behavior in different vertebrate species |
| EP3377069A4 (en) * | 2015-11-17 | 2019-07-03 | Texas Tech University System | Pheromone composition to stimulate reproduction in female suids and methods of use |
| CN110604754A (en) * | 2019-10-14 | 2019-12-24 | 宁波第二激素厂 | Pheromone composition capable of improving estrus mating rate of sows |
| CN110664862A (en) * | 2019-10-14 | 2020-01-10 | 宁波第二激素厂 | Pheromone composition spray preparation and preparation method and application thereof |
| CN111467309A (en) * | 2020-04-16 | 2020-07-31 | 厦门汇承药业有限公司 | Preparation method of boar spray |
| CN112370528A (en) * | 2020-10-23 | 2021-02-19 | 宁波三生生物科技有限公司 | Pheromone composition with marking function and preparation thereof |
-
2010
- 2010-01-20 CN CN201010023023A patent/CN101797257A/en active Pending
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2757888A4 (en) * | 2011-09-20 | 2015-03-18 | Sergeants Pet Care Prod Inc | Interomone compositions and their use to modify behavior in different vertebrate species |
| AU2012312327B2 (en) * | 2011-09-20 | 2016-05-26 | Sergeant's Pet Care Products, Inc. | Interomone compositions and their use to modify behavior in different vertebrate species |
| US9480688B2 (en) | 2011-09-20 | 2016-11-01 | Sergeant's Pet Care Products, Inc. | Pheromone compositions and their use to modify behavior in different vertebrate species |
| EP3377069A4 (en) * | 2015-11-17 | 2019-07-03 | Texas Tech University System | Pheromone composition to stimulate reproduction in female suids and methods of use |
| AU2016358182B2 (en) * | 2015-11-17 | 2021-09-09 | Texas Tech University System | Pheromone composition to stimulate reproduction in female suids and methods of use |
| CN110604754A (en) * | 2019-10-14 | 2019-12-24 | 宁波第二激素厂 | Pheromone composition capable of improving estrus mating rate of sows |
| CN110664862A (en) * | 2019-10-14 | 2020-01-10 | 宁波第二激素厂 | Pheromone composition spray preparation and preparation method and application thereof |
| CN110604754B (en) * | 2019-10-14 | 2021-11-26 | 宁波第二激素厂 | Pheromone composition capable of improving estrus mating rate of sows |
| CN111467309A (en) * | 2020-04-16 | 2020-07-31 | 厦门汇承药业有限公司 | Preparation method of boar spray |
| CN112370528A (en) * | 2020-10-23 | 2021-02-19 | 宁波三生生物科技有限公司 | Pheromone composition with marking function and preparation thereof |
| CN112370528B (en) * | 2020-10-23 | 2022-04-08 | 宁波三生生物科技股份有限公司 | Pheromone composition with marking function and preparation thereof |
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Application publication date: 20100811 |