CN101796034A - 用作烟碱型乙酰胆碱受体的调节剂的新颖的1,2,3-三唑衍生物 - Google Patents

用作烟碱型乙酰胆碱受体的调节剂的新颖的1,2,3-三唑衍生物 Download PDF

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Publication number
CN101796034A
CN101796034A CN200880102108A CN200880102108A CN101796034A CN 101796034 A CN101796034 A CN 101796034A CN 200880102108 A CN200880102108 A CN 200880102108A CN 200880102108 A CN200880102108 A CN 200880102108A CN 101796034 A CN101796034 A CN 101796034A
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phenyl
triazol
trifluoromethyl
ylamine
methoxy
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CN200880102108A
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Chinese (zh)
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A·纳蒂
J·K·克里斯坦森
D·彼德斯
G·M·奥尔森
T·戴赫林
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NTG Nordic Transport Group AS
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Neurosearch AS
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    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
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CN200880102108A 2007-08-08 2008-08-06 用作烟碱型乙酰胆碱受体的调节剂的新颖的1,2,3-三唑衍生物 Pending CN101796034A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA200701134 2007-08-08
DKPA200701134 2007-08-08
US95508107P 2007-08-10 2007-08-10
US60/955,081 2007-08-10
PCT/EP2008/060307 WO2009019278A1 (en) 2007-08-08 2008-08-06 Novel 1,2,3-triazole derivatives useful as modulators of nicotinic acetylcholine receptors

Publications (1)

Publication Number Publication Date
CN101796034A true CN101796034A (zh) 2010-08-04

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CN200880102108A Pending CN101796034A (zh) 2007-08-08 2008-08-06 用作烟碱型乙酰胆碱受体的调节剂的新颖的1,2,3-三唑衍生物

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US (1) US8110588B2 (enExample)
EP (1) EP2185529A1 (enExample)
JP (1) JP2010535738A (enExample)
KR (1) KR20100046179A (enExample)
CN (1) CN101796034A (enExample)
AU (1) AU2008285644A1 (enExample)
CA (1) CA2695812A1 (enExample)
MX (1) MX2010001135A (enExample)
NZ (1) NZ582520A (enExample)
RU (1) RU2010102994A (enExample)
WO (1) WO2009019278A1 (enExample)
ZA (1) ZA201000127B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113045507A (zh) * 2021-03-04 2021-06-29 中山大学南方学院 一种3,4-二羟基苯甲酸甲酯衍生物及其制备方法与应用

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JP2011514906A (ja) * 2008-03-11 2011-05-12 ノイロサーチ アクティーゼルスカブ ニコチン性アセチルコリン受容体のモジュレーターとして有用な新規の１，２，３−トリアゾール誘導体
JP2011530495A (ja) * 2008-08-08 2011-12-22 ノイロサーチ アクティーゼルスカブ ニコチン性アセチルコリン受容体のモジュレーターとして有用な新規のジフェニル１，２，３−トリアゾール誘導体
CA2735773A1 (en) * 2008-09-02 2010-03-11 Neurosearch A/S Triazole derivatives and their use as nicotinic acetylcholine receptor modulators
AR078536A1 (es) 2009-10-07 2011-11-16 Karobio Ab Derivados de pirazol como ligandos del receptor de estrogeno
US20130310419A1 (en) 2011-02-03 2013-11-21 Lupin Limited Pyrrole derivatives used as modulators of alpha7 nachr
AU2012221800B2 (en) 2011-02-23 2016-10-27 Lupin Limited Heteroaryl derivatives as alpha7 nAChR modulators
KR20140025395A (ko) 2011-03-31 2014-03-04 루핀 리미티드 알츠하이머병 및 파킨슨병을 포함하는 신경병성 장애 치료용 니코틴성 아세틸콜린 수용체 조절인자로서의 피롤 유도체
FR2974365B1 (fr) * 2011-04-20 2017-08-25 Centre Nat De La Rech Scient (C N R S) 1,2,3-triazoles 1,4-disubstituees, leurs procedes de preparation et leurs utilisations diagnostiques et therapeutiques
EP2729455B1 (en) 2011-07-05 2016-09-14 Lupin Limited Biaryl derivatives as nachr modulators
GB201113538D0 (en) 2011-08-04 2011-09-21 Karobio Ab Novel estrogen receptor ligands
EP2822946A1 (en) 2012-03-06 2015-01-14 Lupin Limited Thiazole derivatives as alpha 7 nachr modulators
EP2945936A1 (en) 2012-11-12 2015-11-25 Lupin Limited Thiazole derivatives as alpha 7 nachr modulators
US9617211B2 (en) 2013-01-16 2017-04-11 Lupin Limited Pyrrole derivatives as alpha 7 nAChR modulators
CA2892682A1 (en) 2013-03-13 2014-09-18 Lupin Limited Pyrrole derivatives as alpha 7 nachr modulators
TW201446243A (zh) 2013-06-03 2014-12-16 Lupin Ltd 4-(5-(4-氯苯基)-2-(2-環丙基乙醯基)-1,4-二甲基-1氫-吡咯-3-基)苯磺醯胺作為α7尼古丁乙醯膽鹼受體調節劑
CA2913987A1 (en) 2013-06-17 2014-12-24 Lupin Limited Pyrrole derivatives as alpha 7 nachr modulators
WO2019124577A1 (ko) * 2017-12-20 2019-06-27 재단법인 경기도경제과학진흥원 트리아졸 유도체 및 이의 용도

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DE1242216B (de) 1963-12-27 1967-06-15 Union Carbide Corp Verfahren zur Herstellung von Inaminsalzen
JP4299139B2 (ja) 2001-12-18 2009-07-22 メルク エンド カムパニー インコーポレーテッド 代謝型グルタミン酸受容体−５のヘテロアリール置換トリアゾールモジュレータ
US7320994B2 (en) * 2002-04-26 2008-01-22 Eli Lilly And Company Triazole derivatives as tachykinin receptor antagonists
JP5002452B2 (ja) 2004-05-06 2012-08-15 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 置換エナミノン類、それらの誘導体およびそれらの使用
WO2006071184A1 (en) 2004-12-28 2006-07-06 Astrazeneca Ab Aryl sulphonamide modulators
JP2011514906A (ja) 2008-03-11 2011-05-12 ノイロサーチ アクティーゼルスカブ ニコチン性アセチルコリン受容体のモジュレーターとして有用な新規の１，２，３−トリアゾール誘導体
JP2011530495A (ja) 2008-08-08 2011-12-22 ノイロサーチ アクティーゼルスカブ ニコチン性アセチルコリン受容体のモジュレーターとして有用な新規のジフェニル１，２，３−トリアゾール誘導体

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113045507A (zh) * 2021-03-04 2021-06-29 中山大学南方学院 一种3,4-二羟基苯甲酸甲酯衍生物及其制备方法与应用

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US8110588B2 (en) 2012-02-07
WO2009019278A1 (en) 2009-02-12
RU2010102994A (ru) 2011-09-20
AU2008285644A1 (en) 2009-02-12
JP2010535738A (ja) 2010-11-25
MX2010001135A (es) 2010-03-09
CA2695812A1 (en) 2009-02-12
US20100222398A1 (en) 2010-09-02
KR20100046179A (ko) 2010-05-06
ZA201000127B (en) 2011-03-30
EP2185529A1 (en) 2010-05-19

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