CN101795683A - 用于促进警醒症的方法 - Google Patents
用于促进警醒症的方法 Download PDFInfo
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- CN101795683A CN101795683A CN200880105586A CN200880105586A CN101795683A CN 101795683 A CN101795683 A CN 101795683A CN 200880105586 A CN200880105586 A CN 200880105586A CN 200880105586 A CN200880105586 A CN 200880105586A CN 101795683 A CN101795683 A CN 101795683A
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- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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- A—HUMAN NECESSITIES
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A—HUMAN NECESSITIES
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Landscapes
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- Emergency Medicine (AREA)
- Anesthesiology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Psychiatry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US96120707P | 2007-07-18 | 2007-07-18 | |
| US60/961,207 | 2007-07-18 | ||
| PCT/US2008/008773 WO2009011901A2 (en) | 2007-07-18 | 2008-07-18 | Methods for promoting wakefulness |
Publications (1)
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|---|---|
| CN101795683A true CN101795683A (zh) | 2010-08-04 |
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| CN200880105586A Pending CN101795683A (zh) | 2007-07-18 | 2008-07-18 | 用于促进警醒症的方法 |
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| US (1) | US20090048229A1 (cg-RX-API-DMAC10.html) |
| EP (1) | EP2182938A2 (cg-RX-API-DMAC10.html) |
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| CN (1) | CN101795683A (cg-RX-API-DMAC10.html) |
| AU (1) | AU2008276459A1 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2693110A1 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2009011901A2 (cg-RX-API-DMAC10.html) |
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| US8101782B2 (en) | 2007-02-02 | 2012-01-24 | Colucid Pharmaceuticals, Inc. | Compounds that inhibit cholinesterase |
| EP2413926A2 (en) * | 2009-04-02 | 2012-02-08 | Colucid Pharmaceuticals, Inc. | Compositions of cholinesterase inhibitors |
| WO2012047543A1 (en) * | 2010-09-27 | 2012-04-12 | E.I. Du Pont De Nemours And Company | Method for preparing 2-amino-n-(2,2,2-trifluoroethyl) acetamide |
| KR20180069934A (ko) * | 2011-07-28 | 2018-06-25 | 켐팜 인코포레이티드 | 메틸페니데이트 프로드러그, 이의 제조 방법 및 사용 방법 |
| ES2545836B1 (es) * | 2014-03-13 | 2016-07-07 | Elaborados Castellano, S.L. | Composición potenciadora de vigilia, y usos de la misma |
| JPWO2019112007A1 (ja) * | 2017-12-07 | 2020-12-24 | 国立大学法人 筑波大学 | 鎮痛薬による眠気の予防または治療薬 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US3600427A (en) * | 1967-05-08 | 1971-08-17 | Anthony J Verbiscar | Phenyl carbamate latentiated phenethylamines |
| IL74497A (en) * | 1985-03-05 | 1990-02-09 | Proterra Ag | Pharmaceutical compositions containing phenyl carbamate derivatives and certain phenyl carbamate derivatives |
| US4791107A (en) * | 1986-07-16 | 1988-12-13 | Hoechst-Roussel Pharmaceuticals, Inc. | Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use |
| NL195004C (nl) * | 1987-03-04 | 2003-11-04 | Novartis Ag | Fenylcarbamaat bevattend farmaceutisch preparaat. |
| US5187165A (en) * | 1987-05-15 | 1993-02-16 | Hoechst-Roussel Pharmaceuticals Inc. | Memory enhancing and analgesic 1,2,3a,8,8a-hexahydro-3a,8(and 1,3a,8)-di(and tri)methylpyrrolo[2,3-b]indoles |
| IT1251166B (it) * | 1991-08-09 | 1995-05-04 | Chiesi Farma Spa | Derivati di geneserina,loro preparazione e composizioni farmaceutiche che li contengono |
| US5302721A (en) * | 1992-07-21 | 1994-04-12 | Hoechst-Roussel Pharmaceuticals Incorporated | Method of preparation of physostigmine carbamate derivatives from eseretholes |
| US5409948A (en) * | 1992-11-23 | 1995-04-25 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Method for treating cognitive disorders with phenserine |
| SE9504537D0 (sv) * | 1995-12-19 | 1995-12-19 | Jan Hedner | Sätt att behandla och diagnosticera andningsstörningar under sömn och medel för utförande av sättet |
| US5665880A (en) * | 1996-10-31 | 1997-09-09 | Hoechst Marion Roussel, Inc. | Method of preparation of physostigmine carbamate derivatives from eseretholes |
| US5677457A (en) * | 1996-12-19 | 1997-10-14 | Hoechst Marion Roussel, Inc. | Method of preparation of physostigmine carbamate derivatives from eseroline ethers |
| WO1999002154A1 (en) * | 1997-07-09 | 1999-01-21 | Axonyx | Highly selective butyrylcholinesterase inhibitors for the treatment and diagnosis of alzheimer's disease and dementias |
| SE9803760D0 (sv) * | 1998-11-04 | 1998-11-04 | Jan Hedner | Sätt att behandla och diagnostisera syndromet restless legs och motsvarande medel |
| WO2004034963A2 (en) * | 2002-05-17 | 2004-04-29 | Eisai Co., Ltd. | Methods and compositions using cholinesterase inhibitors |
| WO2005016327A2 (en) * | 2003-08-13 | 2005-02-24 | Janssen Pharmaceutica, N.V. | Treatment of sleep disorders with cholinesterase inhibitors |
| US7897639B2 (en) * | 2003-10-21 | 2011-03-01 | Colucid Pharmaceuticals, Inc. | Carbamoyl esters that inhibit cholinesterase and release pharmacologically active agents |
| US8101782B2 (en) * | 2007-02-02 | 2012-01-24 | Colucid Pharmaceuticals, Inc. | Compounds that inhibit cholinesterase |
| ES2431570T3 (es) * | 2007-05-07 | 2013-11-27 | Chelsea Therapeutics, Inc. | Droxidopa y composición farmacéutica de la misma para el tratamiento de los trastornos por déficit de atención |
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- 2008-07-18 WO PCT/US2008/008773 patent/WO2009011901A2/en not_active Ceased
- 2008-07-18 CA CA2693110A patent/CA2693110A1/en not_active Abandoned
- 2008-07-18 EP EP08780244A patent/EP2182938A2/en not_active Withdrawn
- 2008-07-18 CN CN200880105586A patent/CN101795683A/zh active Pending
- 2008-07-18 US US12/218,813 patent/US20090048229A1/en not_active Abandoned
- 2008-07-18 JP JP2010517021A patent/JP2010533717A/ja not_active Withdrawn
- 2008-07-18 AU AU2008276459A patent/AU2008276459A1/en not_active Abandoned
Also Published As
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|---|---|
| US20090048229A1 (en) | 2009-02-19 |
| WO2009011901A3 (en) | 2009-03-26 |
| CA2693110A1 (en) | 2009-01-22 |
| EP2182938A2 (en) | 2010-05-12 |
| JP2010533717A (ja) | 2010-10-28 |
| AU2008276459A1 (en) | 2009-01-22 |
| WO2009011901A2 (en) | 2009-01-22 |
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