CN101795675A - 使用具有Eudragit包衣的Zn/果胶珠粒进行的结肠递送 - Google Patents
使用具有Eudragit包衣的Zn/果胶珠粒进行的结肠递送 Download PDFInfo
- Publication number
- CN101795675A CN101795675A CN200780042460A CN200780042460A CN101795675A CN 101795675 A CN101795675 A CN 101795675A CN 200780042460 A CN200780042460 A CN 200780042460A CN 200780042460 A CN200780042460 A CN 200780042460A CN 101795675 A CN101795675 A CN 101795675A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/50—Hydrolases (3) acting on carbon-nitrogen bonds, other than peptide bonds (3.5), e.g. asparaginase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US85959906P | 2006-11-17 | 2006-11-17 | |
US85960006P | 2006-11-17 | 2006-11-17 | |
US60/859,599 | 2006-11-17 | ||
US60/859,600 | 2006-11-17 | ||
PCT/EP2007/062475 WO2008059062A1 (fr) | 2006-11-17 | 2007-11-16 | Distribution colique à l'aide de billes zn/pectine avec un revêtement d'eudragit |
Publications (1)
Publication Number | Publication Date |
---|---|
CN101795675A true CN101795675A (zh) | 2010-08-04 |
Family
ID=39181811
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN200780042460A Pending CN101795675A (zh) | 2006-11-17 | 2007-11-16 | 使用具有Eudragit包衣的Zn/果胶珠粒进行的结肠递送 |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP2081557A1 (fr) |
JP (1) | JP2010510196A (fr) |
CN (1) | CN101795675A (fr) |
AU (1) | AU2007321111A1 (fr) |
BR (1) | BRPI0719319A2 (fr) |
CA (1) | CA2678131A1 (fr) |
WO (1) | WO2008059062A1 (fr) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2018090266A1 (fr) * | 2016-11-17 | 2018-05-24 | 上海交通大学医学院 | Système d'administration par voie orale ciblant le côlon, et procédé de préparation et application de ce dernier |
CN109562147A (zh) * | 2016-06-28 | 2019-04-02 | 合成生物制品有限公司 | 保护微生物组免受口服抗生素 |
CN110075130A (zh) * | 2013-03-14 | 2019-08-02 | 塞拉拜姆有限责任公司 | 益生生物和/或治疗剂的靶向胃肠道递送 |
CN110381928A (zh) * | 2017-02-01 | 2019-10-25 | 弗劳恩霍夫应用研究促进协会 | 用于肿瘤治疗剂和肿瘤诊断剂的选择性释放系统以及用于肿瘤组织的生物传感器 |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009033724A1 (fr) * | 2007-09-11 | 2009-03-19 | Mondobiotech Laboratories Ag | Utilisation du peptide natriurétique de type c, seul ou en combinaison avec un neuropeptide af comme agent thérapeutique |
CA2698985A1 (fr) * | 2007-09-11 | 2009-03-19 | Mondobiotech Laboratories Ag | Utilisation d'un peptide comme agent therapeutique |
CA2698768A1 (fr) * | 2007-09-11 | 2009-04-02 | Dorian Bevec | Utilisation d'un peptide en tant qu'agent therapeutique |
CZ302789B6 (cs) | 2009-11-25 | 2011-11-09 | Zentiva, K. S. | Zpusob zvýšení rozpustnosti farmaceuticky aktivních látek a cílený (kontrolovaný) transport do streva |
US9572856B2 (en) | 2009-12-16 | 2017-02-21 | The George Washington University a Congressionally Chartered Not-for-Profit Corporation | Method of treating low blood pressure |
SI2538930T1 (sl) * | 2010-02-23 | 2016-10-28 | Da Volterra | Formulacije za oralno dostavo adsorbentov v črevesju |
US20130089585A1 (en) * | 2010-04-08 | 2013-04-11 | Merz Pharma Gmbh & Co., Kgaa | Filler comprising beads |
GB201202433D0 (en) | 2012-02-13 | 2012-03-28 | Diurnal Ltd | Controlled drug release |
CA2910601A1 (fr) * | 2013-04-26 | 2014-10-30 | La Jolla Pharmaceutical Company | Compositions et procedes de traitement de l'insuffisance renale |
WO2015066212A2 (fr) * | 2013-10-31 | 2015-05-07 | University Of Hawaii | Inhibiteurs de la calpaïne destinés au traitement de la maladie inflammatoire chronique de l'intestin et du cancer colorectal |
ES2771749T3 (es) | 2013-12-18 | 2020-07-07 | The George Washington Univ A Congressionally Chartered Not For Profit Corporation | Angiotensina II en combinación para el tratamiento de hipotensión |
CN105828809B (zh) | 2013-12-20 | 2019-10-29 | 费森尤斯卡比德国有限公司 | 包含脂质和活性药剂的具有聚合物涂层的微胶囊 |
WO2016037745A1 (fr) * | 2014-09-11 | 2016-03-17 | Gelita Ag | Particules de gélatine/pectine |
US20160158174A1 (en) * | 2014-12-09 | 2016-06-09 | Intercontinental Great Brands Llc | Enteric-Coated Functional Food Ingredients And Methods For Making The Enteric-Coated Functional Food Ingredients |
WO2017120438A1 (fr) | 2016-01-07 | 2017-07-13 | La Jolla Pharmaceutical Company | Méthodes d'administration d'angiotensine ii |
WO2018191678A1 (fr) | 2017-04-14 | 2018-10-18 | La Jolla Pharmaceutical Company | Méthodes d'administration d'angiotensine ii |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5840332A (en) * | 1996-01-18 | 1998-11-24 | Perio Products Ltd. | Gastrointestinal drug delivery system |
ATE468846T1 (de) * | 2004-03-26 | 2010-06-15 | Lek Pharmaceuticals | Magenresistente pharmazeutische dosierform mit n- (2-(2-phthalimidoethoxy)-acetyl)-l-alanyl-d- glutaminsäure (lk-423) |
CA2608505C (fr) * | 2005-05-18 | 2013-12-24 | Da Volterra | Administration colonique d'adsorbants |
-
2007
- 2007-11-16 EP EP07822689A patent/EP2081557A1/fr not_active Withdrawn
- 2007-11-16 JP JP2009536747A patent/JP2010510196A/ja not_active Withdrawn
- 2007-11-16 BR BRPI0719319-0A patent/BRPI0719319A2/pt not_active Application Discontinuation
- 2007-11-16 CN CN200780042460A patent/CN101795675A/zh active Pending
- 2007-11-16 CA CA002678131A patent/CA2678131A1/fr not_active Abandoned
- 2007-11-16 WO PCT/EP2007/062475 patent/WO2008059062A1/fr active Application Filing
- 2007-11-16 AU AU2007321111A patent/AU2007321111A1/en not_active Abandoned
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110075130A (zh) * | 2013-03-14 | 2019-08-02 | 塞拉拜姆有限责任公司 | 益生生物和/或治疗剂的靶向胃肠道递送 |
CN109562147A (zh) * | 2016-06-28 | 2019-04-02 | 合成生物制品有限公司 | 保护微生物组免受口服抗生素 |
CN109562147B (zh) * | 2016-06-28 | 2023-09-01 | 特里瓦生物制剂有限公司 | 保护微生物组免受口服抗生素 |
WO2018090266A1 (fr) * | 2016-11-17 | 2018-05-24 | 上海交通大学医学院 | Système d'administration par voie orale ciblant le côlon, et procédé de préparation et application de ce dernier |
CN108401418A (zh) * | 2016-11-17 | 2018-08-14 | 上海交通大学医学院 | 口服结肠靶向的递送系统及其制备方法和应用 |
CN108401418B (zh) * | 2016-11-17 | 2023-05-26 | 上海交通大学医学院 | 口服结肠靶向的递送系统及其制备方法和应用 |
CN110381928A (zh) * | 2017-02-01 | 2019-10-25 | 弗劳恩霍夫应用研究促进协会 | 用于肿瘤治疗剂和肿瘤诊断剂的选择性释放系统以及用于肿瘤组织的生物传感器 |
Also Published As
Publication number | Publication date |
---|---|
BRPI0719319A2 (pt) | 2014-02-04 |
WO2008059062A1 (fr) | 2008-05-22 |
EP2081557A1 (fr) | 2009-07-29 |
AU2007321111A1 (en) | 2008-05-22 |
CA2678131A1 (fr) | 2008-05-22 |
JP2010510196A (ja) | 2010-04-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20100804 |