CN101785657B - Confocal micro hard hysteroscope system - Google Patents
Confocal micro hard hysteroscope system Download PDFInfo
- Publication number
- CN101785657B CN101785657B CN2010101087593A CN201010108759A CN101785657B CN 101785657 B CN101785657 B CN 101785657B CN 2010101087593 A CN2010101087593 A CN 2010101087593A CN 201010108759 A CN201010108759 A CN 201010108759A CN 101785657 B CN101785657 B CN 101785657B
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- Prior art keywords
- hysteroscope
- probe
- hard
- confocal micro
- copolymerization
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- 239000000523 sample Substances 0.000 claims abstract description 39
- 238000007334 copolymerization reaction Methods 0.000 claims description 33
- 230000035515 penetration Effects 0.000 claims description 3
- 210000004291 uterus Anatomy 0.000 abstract description 10
- 238000003745 diagnosis Methods 0.000 abstract description 5
- 210000001519 tissue Anatomy 0.000 abstract description 4
- GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical compound O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 abstract description 3
- 229940020947 fluorescein sodium Drugs 0.000 abstract description 3
- 230000003902 lesion Effects 0.000 abstract 3
- 210000004400 mucous membrane Anatomy 0.000 abstract 2
- 238000005516 engineering process Methods 0.000 description 5
- 210000004877 mucosa Anatomy 0.000 description 5
- 231100000915 pathological change Toxicity 0.000 description 5
- 230000036285 pathological change Effects 0.000 description 5
- 206010028980 Neoplasm Diseases 0.000 description 3
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000000007 visual effect Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000001574 biopsy Methods 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000002301 combined effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000010253 intravenous injection Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 210000003101 oviduct Anatomy 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 210000001082 somatic cell Anatomy 0.000 description 1
Images
Abstract
The invention belongs to the field of medical instruments and apparatuses, and discloses a confocal micro hard hysteroscope system comprising a hard hysterscope. The confocal micro hard hysteroscope system further comprises a confocal micro probe and a confocal micro probe system host machine; the hard hysteroscope system is at least provided with a straight line type channel for instruments and apparatuses; the confocal micro probe comprises a working end part and an interface; and the working end part of the confocal micro probe penetrates through the straight line type channel for instruments and apparatuses to combine the hard hysteroscope with the confocal micro probe. In the confocal micro hard hysteroscope system, the advanced confocal laser scanning microtechnology is introduced into the diagnosis of gynecologic operation; the lesions of uterine mucous membrane or cancerization and the like can be clearly observed by putting the confocal micro probe into an uterine cavity through the channel for instruments and apparatuses of the hard hysteroscope and amplifying the tissue by more than 500 times by the confocal micro probe under the combined action of fluorescein sodium; the recognition of the uterus and the lesions thereof is led to the microscopic world, thereby making positioning and qualitative diagnosis of living body cells; and the confocal micro hard electronic hysteroscope system provides a powerful tool for the recognition of the uterine mucous membrane and the lesions thereof, and provides reliable basis for the treatment and research.
Description
Technical field
The invention belongs to field of medical appliances, be specifically related to a kind of core medical instrument that modern medicine is carried out gynecilogical operation.
Prior art
At present, hysteroscope and hysteroscope technology are widely used clinically, it is the important tool of gynecology examination and treatment disease, but the existing hysteroscope that is used for the intrauterine disease diagnosis and treatment can be determined the focus of uterine cavity, there is the insufficient hidden danger of diagnostic accuracy in the variation that it can't understand each layer of uterine cavity and surrounding organ.In order to solve the insufficient problem of diagnostic accuracy, the applicant's the patent No. is: 200920006033.1 (notification number is CN201299586) denomination of invention is a ultrasonic hysteroscope, this ultrasonic hysteroscope adopts miniature ultrasonic technology that uterine cavity is carried out ultrasonic scanning, but also do not have a kind of under the situation of live body uterine cavity mucomembranous cell to its technology of diagnosing.
The burnt microtechnique of copolymerization can provide the cyto-architectural details of mucosal wall interbed clearly as a kind of brand-new imaging technique, clearly shows the surface structure of mucous layer, positions biopsy.At present, the Laser Scanning Confocal Microscope technology is used widely in biological study, its application expands in the research work of subjects such as cytology, microbiology, developmental biology, hereditism, neurobiology, physiology and pathology at present, becomes the important tool of modern biology microexamination.Therefore, how the burnt microtechnique of copolymerization is organically combined with hysteroscope and use, being implemented under the situation of biological tissue accurate positioning and qualitative, that cavity of uterus mucosa or tumor are carried out detailed inspection is particularly urgent.
Summary of the invention
In order to overcome above-mentioned the deficiencies in the prior art, the objective of the invention is to burnt microtechnique of copolymerization and hard hysteroscope are organically combined, by the burnt micro-probe of copolymerization cavity of uterus wall mucosa is carried out the microexamination diagnosis and treatment, propose a kind of confocal micro-rigid hysteroscope system.
For realizing above-mentioned technical purpose, the present invention is achieved through the following technical solutions:
Confocal micro-rigid hysteroscope system of the present invention comprises hard hysteroscope and the cold light source main frame that is connected with the hard hysteroscope, shooting main frame; The hysteroscope sheath tube portion that described hard hysteroscope comprises the main body endoscope part, is connected with the main body endoscope part; Described hard hysteroscope comprises hard scope end, the instrument channel, eyepiece input, the cold light source input that are connected with hard scope end; Described hysteroscope sheath tube portion comprises sheath tube body, the intake tunnel, the exhalant canal that are communicated with the sheath tube body and is arranged at the sheath tube end of sheath tube body front end; Also comprise burnt micro-probe of copolymerization and the burnt micro-probe system main frame of copolymerization; Described hard hysteroscope is provided with straight line type instrument channel at least; The burnt micro-probe of described copolymerization comprises work end and interface; The work end of the burnt micro-probe of described copolymerization is passed this linear type instrument channel the hard hysteroscope is focused on micro-probe combination together.
In the present invention, the described linear type instrument channel diameter that is used for passing to the work end of the burnt micro-probe of copolymerization is smaller or equal to 3.0mm.
In addition, the diameter of the work end of the burnt micro-probe of described copolymerization is smaller or equal to 3.0mm, its length is less than 2000mm, work end penetration depth of penetrate tissue in uterine cavity of the burnt micro-probe of copolymerization is 30 to 80 μ m, the width of absolute visual field scope is 325 μ m, and the burnt micro-probe system of copolymerization can amplify more than 500 times to observed object.
As the further improvement of above-mentioned technology, be connected with burnt main frame of copolymerization and medical monitor on the burnt micro-probe of described copolymerization, so that operation and supervision; Described hard hysteroscope also is connected with medical monitor; Also comprise with each medical monitor and be connected the keyboard of being convenient to operate.
Compared with prior art, the invention has the beneficial effects as follows:
Confocal micro-rigid hysteroscope system of the present invention be the basis of hard hysteroscope on, introduce the burnt micro-probe of advanced copolymerization, the burnt micro-probe of copolymerization is that platform enters in the uterine cavity by the special equipment passage of hard hysteroscope, under the combined effect of fluorescein sodium, uterine cavity mucosa and pathological changes thereof are amplified more than 500 times,, brought up to microcosmos the understanding of uterus, uterus pathological changes, thereby to active somatic cell make the location and etiologic diagnosis, for the treatment and research reliable basis is provided.
Description of drawings
Fig. 1 is a confocal micro-rigid hysteroscope system sketch map of the present invention.
Fig. 2 is a hard hysteroscope sketch map of the present invention.
Fig. 3 is the burnt micro-probe sketch map of copolymerization of the present invention.
Fig. 4 is that sketch map is used in focusing microscopic hard hysteroscope system operation of the present invention.
The specific embodiment
The present invention is described in further detail below in conjunction with accompanying drawing:
The hard hysteroscope 1 that Fig. 1 comprises for confocal micro-rigid hysteroscope system of the present invention, endoscopic cold light source main frame 3, shooting main frame 4, the burnt micro-probe 2 of copolymerization, the burnt micro-probe system main frame 5 of copolymerization and keyboard 6, two medical monitors 7 and 8 show the image of the burnt micro-probe 2 of hard hysteroscope 1 and copolymerization respectively.
Fig. 2 is the sketch map of the hard hysteroscope 1 among the present invention, and hard hysteroscope 1 is divided into two parts, is respectively sheath tube portion 11 and main body endoscope part 12.Described main body endoscope part 12 comprises hard scope end, the rectilinearity instrument channel 121, eyepiece input, the cold light source input that are connected with hard scope end, and the internal diameter of the instrument channel 121 of main body endoscope part 12 is smaller or equal to 3.0mm. Described hysteroscope sheath tube portion 11 comprises sheath tube body, the intake tunnel, the exhalant canal that are communicated with the sheath tube body and is arranged at the sheath tube end of sheath tube body front end.
Fig. 3 is the structure diagram of the burnt micro-probe 2 of copolymerization among the present invention.The burnt micro-probe 2 of described copolymerization comprises work end 21 and interface 22; The linear type instrument channel 121 that hard hysteroscope 1 is passed in the work end 21 of the burnt micro-probe 2 of described copolymerization focuses on micro-probe 2 combinations together with the hard hysteroscope, work end 21 diameters of the burnt micro-probe 2 of copolymerization are smaller or equal to 3.0mm, its length is less than 2000mm, work end penetration depth of penetrate tissue in uterine cavity of the burnt micro-probe of copolymerization is 30 to 80 μ m, the width of absolute visual field scope is 325 μ m, lateral resolution 3.5 μ m.
As Fig. 4, in conjunction with Fig. 1, the operation sketch map of confocal micro-rigid hysteroscope system of the present invention, the doctor at first needs the patient is carried out the intravenous injection fluorescein sodium before the art, hard hysteroscope 1 enters cavity of uterus 9 intracavity, the doctor can clearly observe the pathological changes situation of cavity of uterus 9 by the medical grade monitor 7 of hard hysteroscope, the burnt micro-probe 2 of copolymerization is a platform by the instrument channel 121 of hard hysteroscope 1, enter in the cavity of uterus 9, can amplify more than 500 times to pathological changes such as cavity of uterus 9 or fallopian tube 91 mucosas or tumors, carry out live body and detect, the doctor can diagnose pathological changes such as cavity of uterus mucosa or tumors and treat immediately.
Claims (2)
1. confocal micro-rigid hysteroscope system comprises hard hysteroscope and the cold light source main frame that is connected with the hard hysteroscope, shooting main frame; The hysteroscope sheath tube portion that described hard hysteroscope comprises the main body endoscope part, is connected with the main body endoscope part; Described hard hysteroscope comprises hard scope end, the instrument channel, eyepiece input, the cold light source input that are connected with hard scope end; Described hysteroscope sheath tube portion comprises sheath tube body, the intake tunnel, the exhalant canal that are communicated with the sheath tube body and is arranged at the sheath tube end of sheath tube body front end; It is characterized in that: also comprise burnt micro-probe of copolymerization and the burnt micro-probe system main frame of copolymerization; Described hard hysteroscope is provided with straight line type instrument channel at least; The burnt micro-probe of described copolymerization comprises work end and interface; The work end of the burnt micro-probe of described copolymerization is passed this linear type instrument channel the hard hysteroscope is focused on micro-probe combination together; The diameter of the work end of the burnt micro-probe of described copolymerization is smaller or equal to 3.0mm, its length is less than 2000mm, work end penetration depth of penetrate tissue in uterine cavity of the burnt micro-probe of described copolymerization is 30 to 80 μ m, the width of its maximum observation field range is 325 μ m, lateral resolution 3.5 μ m.
2. confocal micro-rigid hysteroscope system according to claim 1 is characterized in that: the linear type instrument channel diameter that is used for passing to the work end of the burnt micro-probe of copolymerization is smaller or equal to 3.0mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010101087593A CN101785657B (en) | 2010-02-04 | 2010-02-04 | Confocal micro hard hysteroscope system |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010101087593A CN101785657B (en) | 2010-02-04 | 2010-02-04 | Confocal micro hard hysteroscope system |
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| Publication Number | Publication Date |
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| CN101785657A CN101785657A (en) | 2010-07-28 |
| CN101785657B true CN101785657B (en) | 2011-11-23 |
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| CN2010101087593A Expired - Fee Related CN101785657B (en) | 2010-02-04 | 2010-02-04 | Confocal micro hard hysteroscope system |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011097870A1 (en) * | 2010-02-12 | 2011-08-18 | 广州市番禺区胆囊病研究所 | Integrated confocal microscopic hard endoscope system |
| WO2012006767A1 (en) * | 2010-07-15 | 2012-01-19 | 广州宝胆医疗器械科技有限公司 | Therapeutic and diagnostic confocal microscopic rigid endoscope system |
| CN102100519A (en) * | 2010-12-10 | 2011-06-22 | 广州宝胆医疗器械科技有限公司 | Hysteroscope system with infrared thermal scanning function |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201609350U (en) * | 2010-02-04 | 2010-10-20 | 广州宝胆医疗器械科技有限公司 | Confocal micro hard hysteroscope system |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201609350U (en) * | 2010-02-04 | 2010-10-20 | 广州宝胆医疗器械科技有限公司 | Confocal micro hard hysteroscope system |
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| CN101785657A (en) | 2010-07-28 |
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