CN202821285U - Composite endoscopic imaging system based on optical coherence tomography - Google Patents
Composite endoscopic imaging system based on optical coherence tomography Download PDFInfo
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- CN202821285U CN202821285U CN 201220448509 CN201220448509U CN202821285U CN 202821285 U CN202821285 U CN 202821285U CN 201220448509 CN201220448509 CN 201220448509 CN 201220448509 U CN201220448509 U CN 201220448509U CN 202821285 U CN202821285 U CN 202821285U
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Abstract
The utility model discloses a composite endoscopic imaging system based on optical coherence tomography. The composite endoscopic imaging system based on optical coherence tomography comprises a endoscopic imaging device which is provide with an optical coherence tomography controlled by computer control unit, a photoelectronic imaging or a guiding fiber optics bundle imaging system. The endoscopic imaging device comprises a reference arm and an endoscope with a sample arm, the endoscope is provided with a plurality of passages, the passages is provided with an OTC imaging probe, a photoelectronic imaging probe, and a light fiber bundle. By the combination of the OTC imaging and the photoelectronic imaging and the guiding fiber optics bundle imaging, the tissular surface of the observation place and the real surrounded video image can be obtained in real-time, and two dimension cross-sectional images under the certain depth of the epidermis can also be obtained. The composite endoscopic imaging system based on optical coherence tomography is further added visible light source2 to couple with the OCT imaging system, thus making the scanning light of the OCT imaging probe pinpointing to the object region, and realizing the accurate positioning and scanning to the sample tissular thepathological field.
Description
Technical field
This utility model relates to a kind of endoscope apparatus, relates in particular to a kind of compound endoscopic imaging system based on OCT; Belong to the endoscopic imaging technical field.
Background technology
The core technology of conventional endoscope adopts to lead as fibre bundle mostly carries out imaging or adopts photoelectronic imaging to carry out imaging, this type of endoscope only can observe from tissue surface, yet often the symptom of early-stage cancer betides the following 1-3 mm depth of epidermis, and therefore above-mentioned endoscope seems helpless.The endoscope that carries out medical imaging by ultrasonic principle is also arranged in addition, and this type of endoscope can obtain organizational information darker below the biological tissue top layer, but resolution only is the millimeter magnitude, can not carry out effective diagnosis and detection to microscopic structure.
For addressing the above problem, this utility model endoscope apparatus combines photoelectronic imaging with the OCT imaging, for satisfying the OCT based endoscopic imaging, OCT in this utility model endoscope probe adopts based on micro electro mechanical system (MEMS) technology (microelectromechanical systems, abbreviation MEMS) scanning micro-mirror carries out optical scanning, can make the OCT probe size enough little in order to insert smoothly the particularly use in human body alimentary canal of various passages, the application of OCT imaging technique in human body is subject to the microminiaturization of OCT optic probe always.
This utility model endoscope apparatus has solved the faultage image problem that conventional endoscope can not obtain pathological tissues, the OCT image of this utility model device has micron order resolution, may detect the ability of minute lesion under the human body viscera top layer, thereby realize the early lesion diagnosis, especially the first killer of the mankind--on the early diagnosis of cancer, have bright prospects.The utlity model has harmless noinvasive and real-time characteristics, section need not to take a sample, just can be the accurately errorless pathological tissues that finds, diagnosis and operation can be carried out simultaneously, help the doctor to implement more accurate operation technique, removal lesion tissue accurately can alleviate recovery time after patient's misery and the desmopyknosis in addition greatly.
The utility model content
This utility model purpose is to provide a kind of for the defective that prior art exists the OCT optical image technology is applied to endoscope, and annex simultaneously the function that conventional endoscope obtains video image, can be used for auxiliary detection and the diagnosis of early lesion in the human body, accurate biopsy sampling and surgical navigational, and the clinical practice such as monitoring after operation.This utility model is except industrial endoscope is used, be mainly used in the noinvasive to the inside of human body tissue, real-time, high resolution three-dimensional imaging, its resolution can effectively be told majority and come from 2-3 millimeter under the organ epidermis up to 1～10 micron, early cancer's cell of several microns sizes in the epithelial tissue.The early lesion that can be applicable to each internal organs (lung, intestinal, liver, bladder etc.) detects.
This utility model adopts following technical scheme for achieving the above object:
A kind of compound endoscopic imaging system based on OCT, comprise by calculation control unit control with OCT imaging system and photoelectronic imaging or the endoscopic imaging device of leading picture fibre bundle imaging system; Described endoscopic imaging device comprises reference arm and with the endoscope of sample arm; Be provided with a plurality of passages in the described endoscope, be provided with OCT imaging probe, photoelectronic imaging probe in the described passage or lead picture fibre bundle and fibre-optic bundle.
Further, described endoscope apparatus also comprises swept light source, visible light source, cold light source, detector, 2*1 fiber coupler and blender; Described swept light source is sent to calculation control unit with triggering signal; Described swept light source be connected the outfan of visible light source and connect the input of described 2*1 fiber coupler, the outfan of described 2*1 fiber coupler is connected with blender, the light path output port of described blender is connected respectively to reference arm and sample arm; The input of described detector connects the electric signal output port of blender, and its outfan connects calculation control unit; Described cold light source is connected with fibre-optic bundle in the described sample arm; Photoelectronic imaging device in the described sample arm or the optical signal of leading as fibre bundle transfer to calculation control unit with analog electrical signal after opto-electronic conversion.
Further, described reference arm is comprised of the stationary mirror of condenser lens and coating.
Further, described calculation control unit comprises data collecting card, CPU center, display unit and driving panel; The input of described data collecting card is connected with swept light source electric signal end, detector outfan and the photoelectronic imaging passage of being connected in the sample arm respectively, and its outfan is connected to display unit by the CPU center; The input of described driving panel connects the CPU center, and outfan is connection data capture card and OCT imaging probe respectively.
Be provided with 4 or 5 passages when further, described endoscope is for diagnosis endoscope; It comprises when being 4 passages: an OCT imaging probe passage, and two optical fibers beam passages and photoelectronic imaging imaging probe passage or one lead picture fibre bundle passage; It comprises when being 5 passages: an OCT imaging probe passage, two optical fibers beam passages and two photoelectronic imaging probe passages or two lead picture fibre bundle passage.
Further, described endoscope is for diagnosis be provided with 5 passages when performing the operation compound endoscope; Comprise: OCT imaging probe passage, two optical fibers beam passages, photoelectronic imaging probe passage or one lead picture fibre bundle passage and an operating theater instruments passage.
Further, described endoscope also comprises handle interface module, connection tube and the endoscope distal end that sets gradually; Described connection tube is flexible steel in flat section tubing or soft or hard connection tube or rigid connection pipe.
Further, be provided with the constant aperture passage in the described endoscope, described OCT imaging probe directly inserts in this constant aperture passage, adjusts probe positions by stretching OCT imaging probe connection tube.
Further, described OCT imaging probe comprises MEMS micro mirror, lens subassembly, window, electrical connections and shell; Described lens subassembly focuses on input beam and after the reflection of MEMS micro mirror, sees through window and penetrate at sample surfaces.
Further, also comprise stationary mirror in the described OCT imaging probe, described lens subassembly input beam is focused on and after the stationary mirror reflection directive MEMS micro mirror, after the reflection of MEMS micro mirror, see through window again and penetrate at sample surfaces.
Further, described OCT imaging probe and endoscope path way adopt the connected mode of bonding or welding to form an integral body, adjust probe window and sample present position by adjusting described endoscope position.
Further, described OCT imaging probe has side direction, forward direction and three kinds of scanning imagery working methods of side forward direction; When it was side direction, probe window was arranged at OCT imaging probe sidewall; When it was forward direction or side forward direction, probe window was arranged at OCT imaging probe front end.
The beneficial effects of the utility model: (1) combines the OCT imaging with photoelectronic imaging, the two dimension of sample tissue, three-dimensional real video image both can have been obtained in real time, can also obtain in real time two dimension, the three-dimensional optical faultage image of target area, and the high-resolution with several micron levels, can provide enough abundant sample tissue information to the doctor as medical endoscope, for the doctor provides foundation to the Accurate Diagnosis of pathology;
(2) can enter human oral cavity, otorhinolaryngology, bronchus, upper digestive tract and abdominal cavity by endoscope of the present utility model, various suspected lesion tissues are accurately scanned to obtain its optical section to be diagnosed again, biological tissue takes a sample and section and save, greatly alleviate patient's misery and shorten detection time, in view of this utility model endoscope has adopted the MEMS optic probe, so that endoscope's insertion connection tube diameter is enough little;
(3) adopt multichannel endoscope by this utility model, number of channels generally can be less than 5, can not only can be used as diagnostic tool respectively as diagnosis endoscope and operation endoscope, can also carry out the hands art by endoscope channel;
(4) rigid straight tube structure, soft or hard connecting pipe structure are arranged and flexibly connect tubular construction by this utility model endoscope connection tube, can be in various organs, digestive tract and chamber;
(5) by this utility model endoscope apparatus, utilize visible light source 2 to be coupled into the OCT imaging system, can make OCT imaging probe scanning light beam accurately be positioned to the target area, can realize accurate location and scanning to the sample tissue lesion region;
(6) have pipeline plug-in type and integral structure to cooperate by this utility model endoscope with the combination of OCT imaging probe, the OCT imaging probe is flexible and convenient to use, is convenient to white dismounting and assembling, and is convenient to safeguard;
(7) the OCT imaging probe has forward direction/side forward direction and side direction scanning imagery mode, increases the motility to Sample Scan, can adopt the scan mode that is fit to carry out scanning imagery for different target areas.
(8) the OCT imaging probe adopts the integrated miniature probe size of MEMS micro mirror less, and probe diameter adopts this integrated endoscope of probe can have reduced size generally at 2mm-5mm, can enter smoothly various chambers and catwalk.
Description of drawings
Fig. 1 endoscope apparatus block diagram of the present utility model;
Fig. 2 endoscope distal end face of the present utility model;
Fig. 3 endoscope of the present utility model connecting pipe structure;
Fig. 4 OCT side direction of the present utility model scanning imagery probe occupation mode 1;
Fig. 5 OCT forward direction of the present utility model/side scan forward imaging probe occupation mode 1;
Fig. 6 OCT forward direction of the present utility model/side scan forward imaging probe occupation mode 2;
Fig. 7 OCT side direction of the present utility model scanning imagery probe occupation mode 2.
The specific embodiment
Shown in Figure 1, be a kind of compound endoscopic imaging system based on OCT and photoelectronic imaging, comprise by calculation control unit control with OCT imaging system and photoelectronic imaging or the endoscopic imaging device of leading picture fibre bundle imaging system; Described endoscopic imaging device comprises reference arm and with the endoscope 109 of sample arm; The front end of described endoscope 109 is provided with a plurality of endoscope probe passages, is provided with OCT imaging probe, photoelectronic imaging probe in the described endoscope probe passage or leads picture fibre bundle and fibre-optic bundle 106.
This endoscopic imaging system also comprises swept light source (being light source 1), visible light source (being light source 2), cold light source, detector, 2*1 fiber coupler 102, blender and reference arm 103, and described swept light source is sent to calculation control unit with triggering signal 101.Described swept light source is connected outfan and is connected the input of 2*1 fiber coupler with visible light source, the outfan of described 2*1 fiber coupler is connected with blender, and the light path output port of described blender is connected respectively to reference arm 103 and sample arm; Wherein, reference arm 103 is comprised of the stationary mirror 105 of condenser lens 104 and coating.The input of described detector connects the electric signal output port of blender, and its outfan connects calculation control unit.Described cold light source is connected with fibre-optic bundle in the described sample arm.Photoelectronic imaging device 108 in the described sample arm or the optical signal of leading as fibre bundle transfer to calculation control unit with analog electrical signal after opto-electronic conversion.Described endoscope 109 also comprises handle interface module 116, connection tube 117 and the endoscope distal end 118 that sets gradually.Described calculation control unit comprises data collecting card, CPU center, display unit and driving panel.The input of described data collecting card is connected with electric signal end, the detector outfan of swept light source and the photoelectronic imaging passage of being connected in the sample arm respectively, and its outfan is connected to display unit by the CPU center.The input of described driving panel connects the CPU center, the OCT imaging probe in outfan difference connection data capture card and the described endoscope 109.Wherein, described OCT imaging probe comprises MEMS micro mirror, lens subassembly, window, electrical connections and shell; Described lens subassembly focuses on input beam and after the reflection of MEMS micro mirror, sees through window and penetrate at sample surfaces; The scanning of MEMS micro mirror realizes that probe is to horizontal one dimension or the two-dimensional scan of sample.Can also be provided with stationary mirror in the described OCT imaging probe, described lens subassembly focuses on input beam and directive MEMS micro mirror after the stationary mirror reflection, see through window again after the micro mirror reflection and penetrate at sample surfaces, MEMS micro mirror scanning this moment realizes that also probe is to horizontal one dimension or the two-dimensional scan of sample.
Comprise when it is 5 passages: OCT imaging probe passage 112, two optical fibers beam passages 202 and two photoelectronic imaging probe passages 115 or two lead picture fibre bundle passage 203.Can obtain the sample tissue three-dimensional image by two photoelectronic imaging binocular imagings, scan existing doubt region to carry out the OCT optical imagery by the OCT imaging probe again, endoscope apparatus will provide abundanter pathological diagnosis information to supply diagnosis during the boundary, realize diagnostic function.(in Fig. 2).
Described endoscope is for diagnosis and be provided with 5 passages when performing the operation compound endoscope; Comprise: 202, one photoelectronic imagings of 112, two optical fibers beam passages of OCT imaging probe passage probe passages 115 or one lead picture fibre bundle passage 203 and an operating theater instruments passage 204.At first by photoelectronic imaging and OCT imaging pathology is diagnosed, again operating theater instruments is inserted passage and carried out operation technique, realize the complex function of diagnosis and operation.(right such as Fig. 2).
This utility model endoscope connection tube has 3 kinds of structures, flexible steel in flat section tubing, soft or hard connection tube or rigid connection pipe, the soft endoscope front end is rigid first end 303, link to each other with operating portion by flexible steel in flat section tubing 304, can be used for the operation of the upper and lower digestive tract of human body and some organs or detect diagnosis, as shown in Figure 3 in.The soft or hard endoscope distal end is rigid first end 303, the centre is transitioned into rigid connection pipe 301 by flexible steel in flat section tubing 302, and flexible steel in flat section tubing 304 has the forwards, backwards ability of left and right sides all directions bending, and is more flexible, can be used for abdominal operation or detect diagnosis, left as shown in Figure 3.The rigid endoscope front end is rigid first end 303, and is coupled by rigid direct-connected adapter 305.Can be used for the operation of otorhinolaryngology, bronchus, orthopaedics or brain section or detect diagnosis, right as shown in Figure 3.
Extremely shown in Figure 7 such as Fig. 4.The OCT of this utility model endoscope imaging probe has two kinds of occupation modes, wherein a kind of is that endoscope forms the constant aperture passage, the OCT imaging probe directly inserts in the passage and uses, reach the adjustment probe positions by stretching and shrinking the probe connection tube, use flexibly, can carry out scanning imagery to the sample tissue of various complex environments, here the OCT imaging probe has side direction, forward direction and three kinds of scanning imagery working methods of side forward direction, square probe window 408 among Fig. 4 is arranged at the probe sidewall, and the circular window 508 among Fig. 5 is arranged on the probe front end.
Also include OCT imaging probe 401,501 among Fig. 4, Fig. 5, probe sweep 402,502, probe connection tube 403,503, photoelectronic imaging passage 404,504, elder generation of endoscope end 405,505, optical fibers beam passage 406,506, probe bending direction 407,507, probe window 408,508.
As shown in Figure 6 and Figure 7, be the another kind of occupation mode of the OCT of this utility model endoscope imaging probe, OCT imaging probe and endoscope path way adopt the connected mode of bonding or welding to form an integral body, adjust endoscope position and adjust probe window and sample present position, the OCT imaging probe carries out scanning imagery by side direction window or forward direction or side forward direction window.
Wherein, also include endoscope 601,701 among Fig. 6, Fig. 7, OCT forward direction imaging probe 602, OCT forward direction/side forward direction imaging probe 702, lens subassembly 603,703, stationary mirror 604, probe window 605,704, scanning probe scope 606,705, endoscope distal end face 607,708, MEMS micro mirror 608,707, MEMS electrical lead 609, endoscope path way 610,709, MEMS micro mirror pedestal 706.
OCT forward direction imaging probe window is arranged on the endoscope distal end face, connect tube wall and endoscope path way and form an integral body, the light source that lens subassembly will be introduced endoscope focuses on the directive stationary mirror, directive MEMS micro mirror after reflection, the MEMS micro mirror adopts the micro mirror of electrothermal method work, can realize two-dimensional scan, focused beam sees through window sample is scanned, and can obtain the sample three-dimensional tomographic image in conjunction with the OCT imaging system.
Fig. 1 as can be known, its operation principle is: the light source 1 in this utility model endoscopic system is the swept light source that has than short-phase dry length, it is sent to data collecting card with triggering signal (Time trigger) 101, light source 2 is visible light sources that photoelectronic imaging can be responded to, light source 1 is sent to blender after being coupled through the 2*1 fiber coupler with light source 2 two-way light, respectively this hybrid light source is sent to respectively the OCT of endoscope imaging probe end in reference arm and the sample arm through the blender light-splitting processing, the light of returning through the sample diffuse scattering when reference arm and sample arm, the two-way light optical path difference that forms will produce interference and enter detector when being in the coherence length scope, through the detector difference processing, can obtain the organizational information of sample different depth, MEMS micro mirror 107 in the OCT imaging probe is done the two and three dimensions tomographic map that one dimension or two-dimensional scan just can obtain respectively sample, driving panel drives for MEMS micro mirror 107 provides electricity, the CPU center is controlled and the data of reading in is processed two Control cards, and display unit shows the two and three dimensions image of sample.
Light source 3 is cold light source, mating plate can obtain respectively R, G, the trichroism rotating light of B after filtration, illuminate sample surfaces by fibre-optic bundle 106, the real image of photoelectronic imaging device 108 sense objects is through opto-electronic conversion, optical signal is converted to the signal of telecommunication and amplify, through the data collecting card collection signal of telecommunication is delivered to the CPU center again and carry out image processing and recovery, convert analogue signal to, by R, G, B delivery outlet or video output, show through display unit, can obtain clear amplification, real sample surfaces image.Obtain the photoelectronic imaging zone 111 of sample by the photoelectronic imaging image, can adopt the OCT probe to carry out optical scanning to interested zone wherein, can obtain the OCT imaging region 110 of sample.
Above-mentioned compound endoscopic imaging method concrete steps based on OCT are as follows:
1) cold light source obtains respectively R, G, the trichroism rotating light of B after the mating plate after filtration, illuminate sample surfaces by fibre-optic bundle, the real image of photoelectronic imaging device sense object is by opto-electronic conversion and amplification, the signal of telecommunication after the amplification is after data collecting card gathers, the signal of telecommunication is delivered to the CPU center carry out image processing and recovery, convert again analogue signal to, obtain the sample surfaces image by R, G, B delivery outlet or video output, and shown by display unit;
2) swept light source and visible light source two-way incident illumination are sent to blender after being coupled through the 2*1 fiber coupler, obtain hybrid light source after blender is processed;
3) hybrid light source that obtains is incident upon sample surfaces after being sent to respectively reference arm and sample arm, and the frequency sweep light that the frequency sweep light of returning through the sample surfaces diffuse scattering and reference arm reflect forms interference signal through blender;
4) interference signal is input to calculation control unit after the detector difference processing;
5) interference signal of calculation control unit after to difference processing carries out Fourier transformation, obtains sample along the image of depth direction;
6) the MEMS micro mirror in the calculation control unit control OCT imaging probe carries out one dimension or two-dimensional scan to the target area in the photoelectronic imaging zone, and at each scanning element repeating step 2)-5), obtain sample two and three dimensions tomographic map, and show by display unit.
The above only is preferred embodiment of the present utility model, and is in order to limit this utility model, not all within spirit of the present utility model and principle, any modification of doing, is equal to replacement, improvement etc., all should be included within the protection domain of the present utility model.
Claims (12)
1. the compound endoscopic imaging system based on OCT is characterized in that, comprise by calculation control unit control with OCT imaging system and photoelectronic imaging or the endoscopic imaging device of leading picture fibre bundle imaging system; Described endoscopic imaging device comprises reference arm and with the endoscope of sample arm; Be provided with a plurality of passages in the described endoscope, be provided with OCT imaging probe, photoelectronic imaging probe in the described passage or lead picture fibre bundle and fibre-optic bundle.
2. the compound endoscopic imaging system based on OCT as claimed in claim 1 is characterized in that, described endoscopic imaging device also comprises swept light source, visible light source, cold light source, detector, 2*1 fiber coupler and blender; Described swept light source is sent to calculation control unit with triggering signal; Described swept light source be connected the outfan of visible light source and connect the input of described 2*1 fiber coupler, the outfan of described 2*1 fiber coupler is connected with blender, the light path output port of described blender is connected respectively to reference arm and sample arm; The input of described detector connects the electric signal output port of blender, and its outfan connects calculation control unit; Described cold light source is connected with fibre-optic bundle in the described sample arm; Photoelectronic imaging device in the described sample arm or the optical signal of leading as fibre bundle transfer to calculation control unit with analog electrical signal after opto-electronic conversion.
3. the compound endoscopic imaging system based on OCT as claimed in claim 1 or 2 is characterized in that, described reference arm is comprised of the stationary mirror of condenser lens and coating.
4. the compound endoscopic imaging system based on OCT as claimed in claim 1 or 2 is characterized in that, described calculation control unit comprises data collecting card, CPU center, display unit and driving panel; The input of described data collecting card is connected with swept light source electric signal end, detector outfan and the photoelectronic imaging passage of being connected in the sample arm respectively, and its outfan is connected to display unit by the CPU center; The input of described driving panel connects the CPU center, and outfan is connection data capture card and OCT imaging probe respectively.
5. the compound endoscopic imaging system based on OCT as claimed in claim 1 is characterized in that, described endoscope is provided with 4 or 5 passages when being diagnosis endoscope; It comprises when being 4 passages: an OCT imaging probe passage, and two optical fibers beam passages and photoelectronic imaging imaging probe passage or one lead picture fibre bundle passage; It comprises when being 5 passages: an OCT imaging probe passage, two optical fibers beam passages and two photoelectronic imaging probe passages or two lead picture fibre bundle passage.
6. the compound endoscopic imaging system based on OCT as claimed in claim 1 is characterized in that, described endoscope is for diagnosis and be provided with 5 passages when performing the operation compound endoscope; Comprise: an OCT imaging probe passage, two optical fibers beam passages, photoelectronic imaging imaging probe passage or one lead picture fibre bundle passage and an operating theater instruments passage.
7. such as claim 1 or 5 or 6 described compound endoscopic imaging systems based on OCT, it is characterized in that, described endoscope also comprises handle interface module, connection tube and the endoscope distal end that sets gradually; Described connection tube is flexible steel in flat section tubing or soft or hard connection tube or rigid connection pipe.
8. the compound endoscopic imaging system based on OCT as claimed in claim 7, it is characterized in that, be provided with the constant aperture passage in the described endoscope, described OCT imaging probe directly inserts in this constant aperture passage, adjusts probe positions by stretching OCT imaging probe connection tube.
9. the compound endoscopic imaging system based on OCT as claimed in claim 1 is characterized in that, described OCT imaging probe comprises MEMS micro mirror, lens subassembly, window, electrical connections and shell; Described lens subassembly focuses on input beam and after the reflection of MEMS micro mirror, sees through window and penetrate at sample surfaces.
10. the compound endoscopic imaging system based on OCT as claimed in claim 9, it is characterized in that, also comprise stationary mirror in the described OCT imaging probe, described lens subassembly input beam is focused on and after the stationary mirror reflection directive MEMS micro mirror, after the reflection of MEMS micro mirror, see through window again and penetrate at sample surfaces.
11. such as claim 1 or 9 or 10 described compound endoscopic imaging systems based on OCT, it is characterized in that, described OCT imaging probe and endoscope path way adopt the connected mode of bonding or welding to form an integral body, adjust probe window and sample present position by adjusting described endoscope position.
12. the compound endoscopic imaging system based on OCT as claimed in claim 1 is characterized in that, described OCT imaging probe has side direction, forward direction and three kinds of scanning imagery working methods of side forward direction; When it was side direction, probe window was arranged at OCT imaging probe sidewall; When it was forward direction or side forward direction, probe window was arranged at OCT imaging probe front end.
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102824154A (en) * | 2012-09-04 | 2012-12-19 | 无锡微奥科技有限公司 | Combined endoscope imaging system based on OCT (Optical Coherence Tomography) and imaging method |
| CN104523216A (en) * | 2014-12-10 | 2015-04-22 | 佛山市南海区欧谱曼迪科技有限责任公司 | Hysteroscope system based on optical coherence tomography and implementation method thereof |
| CN105962977A (en) * | 2016-06-16 | 2016-09-28 | 黄可南 | Wireless transmission type pleuroperitoneal minimally-invasive device carrying with OCT technology |
| CN107625512A (en) * | 2017-09-14 | 2018-01-26 | 南方医科大学南方医院 | A kind of OCT laparoscopes structure |
| CN108254663A (en) * | 2018-04-11 | 2018-07-06 | 广东电网有限责任公司 | A kind of novel cable insulating sheath fault location probe and positioning device |
| CN110248588A (en) * | 2017-02-23 | 2019-09-17 | 奥林巴斯株式会社 | Endoscope |
| CN110613510A (en) * | 2018-06-19 | 2019-12-27 | 清华大学 | Self-projection endoscope device |
| WO2020163420A1 (en) * | 2019-02-06 | 2020-08-13 | Qioptiq Photonics Gmbh & Co. Kg | Endoscope system |
| CN113545735A (en) * | 2021-09-18 | 2021-10-26 | 广州永士达医疗科技有限责任公司 | OCT image display adjustment method and device |
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2012
- 2012-09-04 CN CN 201220448509 patent/CN202821285U/en not_active Withdrawn - After Issue
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| CN102824154B (en) * | 2012-09-04 | 2015-03-04 | 无锡微奥科技有限公司 | Combined endoscope imaging system based on OCT (Optical Coherence Tomography) and imaging method |
| CN102824154A (en) * | 2012-09-04 | 2012-12-19 | 无锡微奥科技有限公司 | Combined endoscope imaging system based on OCT (Optical Coherence Tomography) and imaging method |
| CN104523216A (en) * | 2014-12-10 | 2015-04-22 | 佛山市南海区欧谱曼迪科技有限责任公司 | Hysteroscope system based on optical coherence tomography and implementation method thereof |
| CN104523216B (en) * | 2014-12-10 | 2016-04-20 | 佛山市南海区欧谱曼迪科技有限责任公司 | A kind of hysteroscope system based on optical coherence tomography and its implementation |
| CN105962977A (en) * | 2016-06-16 | 2016-09-28 | 黄可南 | Wireless transmission type pleuroperitoneal minimally-invasive device carrying with OCT technology |
| CN110248588A (en) * | 2017-02-23 | 2019-09-17 | 奥林巴斯株式会社 | Endoscope |
| CN107625512A (en) * | 2017-09-14 | 2018-01-26 | 南方医科大学南方医院 | A kind of OCT laparoscopes structure |
| CN108254663A (en) * | 2018-04-11 | 2018-07-06 | 广东电网有限责任公司 | A kind of novel cable insulating sheath fault location probe and positioning device |
| CN110613510A (en) * | 2018-06-19 | 2019-12-27 | 清华大学 | Self-projection endoscope device |
| CN110613510B (en) * | 2018-06-19 | 2020-07-21 | 清华大学 | Self-projection endoscope device |
| WO2020163420A1 (en) * | 2019-02-06 | 2020-08-13 | Qioptiq Photonics Gmbh & Co. Kg | Endoscope system |
| US20220087515A1 (en) * | 2019-02-06 | 2022-03-24 | Qioptiq Photonics Gmbh & Co. Kg | Endoscope system |
| CN113545735A (en) * | 2021-09-18 | 2021-10-26 | 广州永士达医疗科技有限责任公司 | OCT image display adjustment method and device |
| CN113545735B (en) * | 2021-09-18 | 2021-12-14 | 广州永士达医疗科技有限责任公司 | OCT image display adjustment method and device |
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