CN101773569A

CN101773569A - Oral Chinese medicine liquid for treating chicken infectious laryngotracheitis

Info

Publication number: CN101773569A
Application number: CN 201010119768
Authority: CN
Inventors: 张登荣
Original assignee: Hebei University of Engineering
Current assignee: Hebei University of Engineering
Priority date: 2010-03-04
Filing date: 2010-03-04
Publication date: 2010-07-14
Anticipated expiration: 2030-03-04
Also published as: CN101773569B

Abstract

The invention discloses oral Chinese medicine liquid for treating chicken infectious laryngotracheitis. The oral Chinese medicine liquid comprises the following components by weight: 95-105g of wild chrysanthemum flower, 95-105g of hempleaf groundsel herb, 95-105g of Astragalus membranaceus, 95-105g of subprostrate sophora, 95-105g of platycodon root, 45-55g of isatis root, 45-55g of rehmannia, 15-25g of semen armeniacae amarae, 25-35g of coptis, 45-55g of Scutellaria baicalensis, 45-55g of Japanese raisintree fruit, 45-55g of honeysuckle flower, 45-55g of carthamus seed, 45-55g of garden burnet root, 15-25g of fructus forsythiae, 25-35g of fiveleaf gynostemma herb, 25-35g of gypsum and 15-25g of licorice root. The preparation technology comprises: 1. sorting; 2. superfine crushing; 3. soaking; 4. medicine liquid extraction; 5. microwave extraction; 6. filtration; 7. preservative addition; and 8. split charging. The invention has the advantages that the effect of treating chicken ILT and IB is good, the residue is low and the biological safety is good.

Description

A kind of Chinese medicine oral liquid for the treatment of infectious laryngotracheitis of chicken

Technical field

The present invention relates to a kind of Chinese medicine oral liquid for the treatment of respiratory disease of chicken, especially a kind of Chinese medicine oral liquid for the treatment of infectious laryngotracheitis of chicken.

Background technology

At present, to infectious laryngotracheitis of chicken (ILT), infectious bronchitis (IB), mainly use vaccine prevention.But immunity usually causes immuning failure with vaccine strain and epidemic isolates genotypic difference.Infectious bronchitis of chicken is for many years popular in China, and present isolating strain and traditional infectious bronchitis vaccine serum homology are lower, and mostly are kidney type IBV.It is reported that the isolating IBV in Jiangsu Province all is the kidney type, the immuning failure phenomenon is common.Although developed new generation vaccine, lack necessary specific aim selection approach during owing to the clinical practice vaccine, chicken group immune effect is often undesirable.In addition, use vaccine prevention infectious laryngotracheitis of chicken (ILT), infectious bronchitis (IB), chicken plasma glucocorticoid concentration height.Therefore, study a kind of treatment infectious laryngotracheitis of chicken (ILT), infectious bronchitis (IB) effective, can reduce chicken plasma glucocorticoid concentration, virus function is had the Chinese medicine oral liquid of many targets property, low-residual, treatment respiratory disease of chicken that biological safety is good, be the present technical issues that need to address.

Summary of the invention

Technical problem to be solved by this invention provide a kind of treatment infectious laryngotracheitis of chicken (ILT), infectious bronchitis (IB) effective, can reduce chicken plasma glucocorticoid concentration, virus function had the Chinese medicine oral liquid of many targets property, low-residual, treatment respiratory disease of chicken that biological safety is good.

The technical scheme that the present invention solves its technical problem is:

A kind of Chinese medicine oral liquid for the treatment of infectious laryngotracheitis of chicken, its constituent is: Flos Chrysanthemi Indici 95～105g, Herba Senecionis cannabifolii 95～105g, the Radix Astragali 95～105g, Radix Sophorae Tonkinensis 95～105g, Radix Platycodonis 95～105g, Radix Isatidis 45～55g, Radix Rehmanniae 45～55g, Semen Armeniacae Amarum 15～25g, Rhizoma Coptidis 25～35g, Radix Scutellariae 45～55g, Japanese raisintree fruit 45～55g, Flos Lonicerae 45～55g, Fructus Carthami tinctorii 45～55g, Radix Sanguisorbae 45～55g, Fructus Forsythiae 15～25g, Herb Gynostemmae Pentaphylli 25～35g, Gypsum Fibrosum 25～35g, Radix Glycyrrhizae 15～25g, its processing technology is: 1. sort, 2. micronizing, 3. soak, 4. medicinal liquid extracts, and 5. 6. microwave extraction filters, 7. add antiseptic, 8. packing.

The technical scheme that the present invention solves its technical problem can also be:

Its constituent of the present invention is: Flos Chrysanthemi Indici 100g, Herba Senecionis cannabifolii 100g, Radix Astragali 100g, Radix Sophorae Tonkinensis 100g, Radix Platycodonis 100g, Radix Isatidis 50g, Radix Rehmanniae 50g, Semen Armeniacae Amarum 20g, Rhizoma Coptidis 30g, Radix Scutellariae 50g, Japanese raisintree fruit 50g, Flos Lonicerae 50g, Fructus Carthami tinctorii 50g, Radix Sanguisorbae 50g, Fructus Forsythiae 20g, Herb Gynostemmae Pentaphylli 30g, Gypsum Fibrosum 30g, Radix Glycyrrhizae 20g.

Letter sorting of the present invention, promptly remove the impurity in each component, described micronizing, promptly be ground into 200 purpose fine powders with above-mentioned each component weighing and after mixing respectively, described immersion, the medicated powder that is about to crush soaked 3 hours down with the clear water room temperature of 5 times of medicated powder weight, described medicinal liquid extracts, promptly from soaked medicine liquid mixture with medicated powder residue and separating liquid medicine, it is standby to leave and take medicinal liquid, described microwave extraction, the medicinal liquid that is about to extract is condensed into medicinal liquid with the microwave concentration technique concentrated solution of 1 times of former medicated powder weight.

The clear water room temperature that the present invention will soak 5 times of former medicated powder weight of the isolated medicated powder residue reuse in back soaked 3 hours down, and then from through the secondary decoction soaking mixture with medicated powder residue and separating liquid medicine, leave and take medicinal liquid, more mixed medicinal liquid is condensed into the concentrated solution of 1 times of former medicated powder weight after secondary is left and taken medicinal liquid and isolated medicinal liquid is mixed for the first time.

The invention has the beneficial effects as follows:

1, has non-specific immunity;

2, can regulate blood plasma glucocorticoid concentration;

3, can eliminate the immunosuppressant that IBDV causes;

4, because the present invention is a Chinese medicine oral liquid, therefore, residual low even noresidue in the chicken health, biological safety is good;

5, aboundresources, cost are low, easy to use.

Using method of the present invention is:

The present invention is diluted with clear water in 1: 100 ratio, and consumption is chicken one a subnormal amount of drinking water, once-a-day, can cure in 2nd～3.

Clinical testing data of the present invention is as follows: cure rate 96%, effective percentage 100%.

Specify beneficial effect of the present invention below by several routine model cases:

Embodiment 1: your name one broiler plant 10,000 broiler generations laryngitis, with Chinese medicine oral liquid treatment of the present invention, symptom obviously alleviates after 1 day, recovery from illness after 3 days, cure rate 96%, effective percentage 100%.

Embodiment 2: Qingzhou, Shandong one broiler plant 5,000 broiler generations laryngitis, with Chinese medicine oral liquid treatment of the present invention, symptom obviously alleviates after 12 hours, recovery from illness after 3 days, cure rate 97%, effective percentage 100%.

Embodiment 3: laryngitis takes place in 500 laying hens in one breeding layer chicken field, Guantao, Hebei, and with Chinese medicine oral liquid treatment of the present invention, symptom obviously alleviates after 1 day, recovery from illness after 3 days, cure rate 98%, effective percentage 100%.

The specific embodiment

Mode below by tabulation is enumerated 10 specific embodiments of the present invention, whole compositions are market and directly buy, its processing technology is: 1. letter sorting, promptly remove the impurity in each component, 2. micronizing, promptly be ground into 200 purpose fine powders with above-mentioned each component weighing and after mixing respectively, 3. soak, the medicated powder that is about to crush soaked 3 hours down with the clear water room temperature of 5 times of medicated powder weight, 4. medicinal liquid extracts, promptly from soaked medicine liquid mixture with medicated powder residue and separating liquid medicine, it is standby to leave and take medicinal liquid, 5. soak again, promptly the clear water room temperature with the 5 times of former medicated powder weight of medicated powder residue reuse after for the first time medicinal liquid extracts soaked 3 hours down, and 6. medicinal liquid extracts once more, promptly from second time decoction soaking mixture with medicated powder residue and separating liquid medicine, it is standby to leave and take medicinal liquid, 7. microwave extraction, the medicinal liquid that is about to extracted twice are mixed the back and with the microwave concentration technique medicinal liquid are condensed into the concentrated solution of 1 times of former medicated powder weight, 8. filtration, 9. add antiseptic, 10. packing.

Unit: g

	??1	??2	??3	??4	??5	??6	??7	??8	??9	??10
	??1	??2	??3	??4	??5	??6	??7	??8	??9	??10	Flos Chrysanthemi Indici	??95	??104	??97	??99	??100	??103	??102	??98	??96	??105
Herba Senecionis cannabifolii	??95	??104	??97	??99	??100	??103	??102	??98	??96	??105	Flos Chrysanthemi Indici	??95	??104	??97	??99	??100	??103	??102	??98	??96	??105
Herba Senecionis cannabifolii	??95	??104	??97	??99	??100	??103	??102	??98	??96	??105	The Radix Astragali	??95	??104	??97	??99	??100	??103	??102	??98	??96	??105

	??1	??2	??3	??4	??5	??6	??7	??8	??9	??10
	??1	??2	??3	??4	??5	??6	??7	??8	??9	??10	Radix Sophorae Tonkinensis	??95	??104	??97	??99	??100	??103	??102	??98	??96	??105
Radix Platycodonis	??95	??104	??97	??99	??100	??103	??102	??98	??96	??105	Radix Sophorae Tonkinensis	??95	??104	??97	??99	??100	??103	??102	??98	??96	??105
Radix Platycodonis	??95	??104	??97	??99	??100	??103	??102	??98	??96	??105	Radix Isatidis	??45	??54	??46	??53	??50	??52	??47	??48	??49	??55
Radix Rehmanniae	??45	??54	??46	??53	??50	??52	??47	??48	??49	??55	Radix Isatidis	??45	??54	??46	??53	??50	??52	??47	??48	??49	??55
Radix Rehmanniae	??45	??54	??46	??53	??50	??52	??47	??48	??49	??55	Semen Armeniacae Amarum	??15	??25	??18	??23	??20	??17	??20	??19	??16	??25
Rhizoma Coptidis	??25	??34	??26	??32	??30	??28	??25	??35	??30	??35	Semen Armeniacae Amarum	??15	??25	??18	??23	??20	??17	??20	??19	??16	??25
Rhizoma Coptidis	??25	??34	??26	??32	??30	??28	??25	??35	??30	??35	Radix Scutellariae	??45	??54	??46	??53	??50	??52	??47	??48	??49	??55
Japanese raisintree fruit	??45	??54	??46	??53	??50	??52	??47	??48	??49	??55	Radix Scutellariae	??45	??54	??46	??53	??50	??52	??47	??48	??49	??55
Japanese raisintree fruit	??45	??54	??46	??53	??50	??52	??47	??48	??49	??55	Flos Lonicerae	??45	??54	??46	??53	??50	??52	??47	??48	??49	??55
Fructus Carthami tinctorii	??45	??54	??46	??53	??50	??52	??47	??48	??49	??55	Flos Lonicerae	??45	??54	??46	??53	??50	??52	??47	??48	??49	??55
Fructus Carthami tinctorii	??45	??54	??46	??53	??50	??52	??47	??48	??49	??55	Radix Sanguisorbae	??45	??54	??46	??53	??50	??52	??47	??48	??49	??55
Fructus Forsythiae	??15	??25	??18	??23	??20	??17	??20	??19	??16	??25	Radix Sanguisorbae	??45	??54	??46	??53	??50	??52	??47	??48	??49	??55
Fructus Forsythiae	??15	??25	??18	??23	??20	??17	??20	??19	??16	??25	Herb Gynostemmae Pentaphylli	??25	??34	??26	??32	??30	??28	??25	??35	??30	??35
Gypsum Fibrosum	??25	??34	??26	??32	??30	??28	??25	??35	??30	??35	Herb Gynostemmae Pentaphylli	??25	??34	??26	??32	??30	??28	??25	??35	??30	??35
Gypsum Fibrosum	??25	??34	??26	??32	??30	??28	??25	??35	??30	??35	Radix Glycyrrhizae	??15	??25	??18	??23	??20	??17	??20	??19	??16	??25

Claims

1. Chinese medicine oral liquid for the treatment of infectious laryngotracheitis of chicken, it is characterized in that: its constituent is: Flos Chrysanthemi Indici 95～105g, Herba Senecionis cannabifolii 95～105g, the Radix Astragali 95～105g, Radix Sophorae Tonkinensis 95～105g, Radix Platycodonis 95～105g, Radix Isatidis 45～55g, Radix Rehmanniae 45～55g, Semen Armeniacae Amarum 15～25g, Rhizoma Coptidis 25～35g, Radix Scutellariae 45～55g, Japanese raisintree fruit 45～55g, Flos Lonicerae 45～55g, Fructus Carthami tinctorii 45～55g, Radix Sanguisorbae 45～55g, Fructus Forsythiae 15～25g, Herb Gynostemmae Pentaphylli 25～35g, Gypsum Fibrosum 25～35g, Radix Glycyrrhizae 15～25g, its processing technology is: 1. sort, 2. micronizing, 3. soak, 4. medicinal liquid extracts, and 5. 6. microwave extraction filters, 7. add antiseptic, 8. packing.

2. a kind of Chinese medicine oral liquid for the treatment of infectious laryngotracheitis of chicken according to claim 1, it is characterized in that: its constituent is: Flos Chrysanthemi Indici 100g, Herba Senecionis cannabifolii 100g, Radix Astragali 100g, Radix Sophorae Tonkinensis 100g, Radix Platycodonis 100g, Radix Isatidis 50g, Radix Rehmanniae 50g, Semen Armeniacae Amarum 20g, Rhizoma Coptidis 30g, Radix Scutellariae 50g, Japanese raisintree fruit 50g, Flos Lonicerae 50g, Fructus Carthami tinctorii 50g, Radix Sanguisorbae 50g, Fructus Forsythiae 20g, Herb Gynostemmae Pentaphylli 30g, Gypsum Fibrosum 30g, Radix Glycyrrhizae 20g.

3. according to claim 1 and 2 described a kind of Chinese medicine oral liquid for the treatment of infectious laryngotracheitis of chicken, it is characterized in that: described letter sorting, promptly remove the impurity in each component, described micronizing, promptly be ground into 200 purpose fine powders with above-mentioned each component weighing and after mixing respectively, described immersion, the medicated powder that is about to crush soaked 3 hours down with the clear water room temperature of 5 times of medicated powder weight, described medicinal liquid extracts, promptly from soaked medicine liquid mixture with medicated powder residue and separating liquid medicine, it is standby to leave and take medicinal liquid, described microwave extraction, and the medicinal liquid that is about to extract is condensed into medicinal liquid with the microwave concentration technique concentrated solution of 1 times of former medicated powder weight.

4. a kind of Chinese medicine oral liquid for the treatment of infectious laryngotracheitis of chicken according to claim 1, it is characterized in that: the clear water room temperature that will soak 5 times of former medicated powder weight of the isolated medicated powder residue reuse in back soaked 3 hours down, and then from through the secondary decoction soaking mixture with medicated powder residue and separating liquid medicine, leave and take medicinal liquid, more mixed medicinal liquid is condensed into the concentrated solution of 1 times of former medicated powder weight after secondary is left and taken medicinal liquid and isolated medicinal liquid is mixed for the first time.