CN101766718A - Drug combination for treating chronic cholecystitis and preparation method thereof - Google Patents
Drug combination for treating chronic cholecystitis and preparation method thereof Download PDFInfo
- Publication number
- CN101766718A CN101766718A CN200810240675A CN200810240675A CN101766718A CN 101766718 A CN101766718 A CN 101766718A CN 200810240675 A CN200810240675 A CN 200810240675A CN 200810240675 A CN200810240675 A CN 200810240675A CN 101766718 A CN101766718 A CN 101766718A
- Authority
- CN
- China
- Prior art keywords
- parts
- chronic cholecystitis
- drug combination
- preparation
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a drug combination for treating chronic cholecystitis and a preparation method thereof, belonging to the field of the Chinese herba preparation technology; the drug combination is formed by astragalus mongholicus, baikal skullcap root, frankincense, myrrh, radix angelicae, polygonum cuspidatum, dandelion, forsythia, honeysuckle, dried orange peel, fructus aurantii and poria cocos Chinese medicinal crops which are prepared into tablets by weight proportion; the drug combination has the functions of soothing liver-gallbladder, clearing heat and dehumidification, and diminishing inflammation and relieving pain, is mainly used for treating chronic cholecystitis; the drug combination is pure Chinese medicine preparation, has non-toxic side effect, clinical symptoms are disappeared rapidly, treats both principle and secondary aspect of disease and has remarkable curative effect.
Description
Technical field
The invention belongs to the Chinese medicine preparation technical field, be specifically related to a kind of pharmaceutical composition that is used for the treatment of chronic cholecystitis and preparation method thereof.
Background technology
Cholecystitis divides acute and chronic two kinds, sees clinically more, and is higher with women's sickness rate fat, voluminous, about 40 years old especially.Chronic cholecystitis belongs to categories such as Chinese medicine hypochondriac pain, gallbladder-distention, jaundice.Being gallbladder chronic inflammation pathological changes, how delaying outbreak repeatedly by calculus, parasite, chronic infection, chemical lesion and acute cholecystitis and cause, serve as mainly to show with chronic epigastrium dull pain discomfort, dyspepsia etc.
And a chronic cholecystitis part forms for the acute cholecystitis delay, but most acute attack history that previously there is no.About 70% patient is with calculus.Because cholelithiasis stimulates, add that on the basis of long-term chronic inflammatory disease the acute attack of repeated multiple times was arranged, can make atrophy of gallbladder or cyst wall proliferation of fibrous tissue plumpness, cause eventually that blister cavities dwindles, afunction.If cystic duct is calculus, inflammatory adhesion or cicatrix total blockage, bile can't flow to gallbladder, and original bile in the gallbladder, because of bile pigments is absorbed gradually, mucosa is still constantly secreted colourless water sample mucus, can form gallbladder hydrops; Work as secondary infection, then develop into gallbladder empyema.
At present, the medicine of state's internal therapy primary disease is many, and gentamycin antibiotics class medicine can only be alleviated surface symptoms based on simple antibiotic medicine, and curative effect is undesirable, and easily recurrence after the drug withdrawal, and the patient has to take medicine for a long time and keeps, and is easy to generate Drug resistance; Adopt surgical therapy, how based on direct excision gallbladder, it is not suitable for older and is associated with the patient of other organ disease, make the patient be difficult to accept and also financial burden too heavy, long-term effect neither be very desirable; And the employing Chinese patent drugs for treatment has side effect after taking, though cholecystitis pain has alleviation, untoward reaction such as flatulence often occur having a stomach-ache.
Therefore, the present invention follows depressed liver-energy dispersing and function of gallbladder promoting, removing damp-heat, anti-inflammatory analgetic principle, adopts totally ten two flavor Chinese crude drug prescriptions such as the Radix Astragali, Radix Scutellariae, Olibanum, Myrrha, and makes tablet by the certain part by weight proportioning.The present invention is a pure Chinese medicinal preparation, has no side effect, and clinical symptom disappearance is rapid, and treating both the principal and secondary aspects of a disease is evident in efficacy.
Summary of the invention
The invention provides and have no side effect, treating both the principal and secondary aspects of a disease, a kind of pharmaceutical composition that is used for the treatment of chronic cholecystitis evident in efficacy comprises its preparation method, purpose is to select for extensive patients provides new medication, makes things convenient for patient treatment.
The present invention is achieved by the following technical solutions:
A kind of pharmaceutical composition that is used for the treatment of chronic cholecystitis, it is that raw material is formed by following parts by weight of Chinese traditional medicine material:
Radix Astragali 30-80 part Radix Scutellariae 50-120 part Olibanum 30-60 part Myrrha 50-100 part
Radix Angelicae Dahuricae 60-120 part Rhizoma Polygoni Cuspidati 50-140 part Herba Taraxaci 30-90 part Fructus Forsythiae 60-120 part
Flos Lonicerae 50-100 part Pericarpium Citri Reticulatae 60-150 part Fructus Aurantii 40-80 part Poria 70-180 part
And the weight portion proportioning of described each Chinese crude drug raw material is:
75 parts of 45 parts of Myrrhas of 90 parts of Olibanums of 60 parts of Radix Scutellariaes of the Radix Astragali
90 parts of 60 parts of Fructus Forsythiaes of 100 parts of Herba Taraxacis of 90 parts of Rhizoma Polygoni Cuspidati of the Radix Angelicae Dahuricae
130 parts in 60 parts of Poria of 105 parts of Fructus Aurantiis of 80 parts of Pericarpium Citri Reticulataes of Flos Lonicerae
Its preparation method is:
(1) each pulverizing medicinal materials is become coarse powder, mix, decoct with water each 1～3 hour 2～4 times;
(2) decocting liquid filters, and merging filtrate left standstill 4～8 hours;
The supernatant of (3) leaching (2), and being concentrated into 60～80 ℃ of heat, to survey relative densities be 1.33～1.38 thick paste, standby;
(4) with the thick paste that makes, drying is pulverized, and adds conventional auxiliary materials and mixing, and water or Different concentrations of alcohol are made granule, and drying is standby;
(5) in flakes, promptly with dried granule compacting.
Function of the present invention cures mainly and is: depressed liver-energy dispersing and function of gallbladder promoting, removing damp-heat, anti-inflammatory analgetic.Cure mainly chronic cholecystitis.
For beneficial effect of the present invention better is described, we have carried out following clinical experimental study:
1, physical data
40 routine chronic cholecystitis patients are all from hospital's hepatology outpatient service, wherein male 19 examples, women 21 examples; The oldest 58 years old, minimum 28 years old, average 43 years old; The course of disease is the longest 12 years, the shortest March, average 6.1 years.
2, diagnostic criteria
Formulate with reference to " new Chinese medicine is treated the clinical research guideline of chronic biliary tract infection, cholelithiasis ": acute or chronic cholecystitis or cholelithiasis medical history; Gastral cavity side of body portion feeling of distension and oppression does not relax or twinge, omoplate district radiation to the right, and abdominal distention after meal, heating installation is felt sick, the bitter taste xerostomia, it is uncomfortable to defecate, sx behind the fat diet; Companion's gallbladder district's tenderness is is it possible that levy sign such as the positive; Ultrasonic examination show that gallbladder wall is crude or thicken, performance such as atrophy of gallbladder, cholelithiasis.
3, Therapeutic Method
Tablet of the present invention, medicine is formed: Radix Astragali 60g, Radix Scutellariae 90g, Olibanum 45g, Myrrha 75g, Radix Angelicae Dahuricae 90g, Rhizoma Polygoni Cuspidati 100g, Herba Taraxaci 60g, Fructus Forsythiae 90g, Flos Lonicerae 80g, Pericarpium Citri Reticulatae 105g, Fructus Aurantii 60g, Poria 130g makes according to preparation method of the present invention.Oral, every day 3 times, each 2,6 weeks were 1 course of treatment, evaluated curative effect after treating for 2 courses of treatment.Light diet during the treatment, stimulation food avoids pungent food.
4, therapeutic outcome
Criterion of therapeutical effect is drafted with reference to " new Chinese medicine is treated the clinical research guideline of chronic biliary tract infection, cholelithiasis ".
Cure: clinical symptoms, sign disappear, and the ultrasound diagnosis gallbladder is normal, follow up a case by regular visits to not recurrence in 1 year;
Produce effects: clinical symptoms, Signs obviously alleviate, and the ultrasound diagnosis gallbladder inflammation obviously alleviates;
Effectively: clinical symptoms, sign take a turn for the better, and attack times reduces;
Invalid: clinical symptoms, sign, ultrasound diagnosis all do not have change, even increase the weight of.
The result shows, among the 40 routine patients, cures 18 examples, produce effects 12 examples, effective 8 examples, invalid 2 examples, total effective rate 95%.
The specific embodiment of form is described in further detail foregoing of the present invention by the following examples.Following example is based on the above-mentioned subject area of the present invention, but is not limited to following example.
The specific embodiment
Embodiment 1:
Adopt following drug regimen:
Radix Astragali 60g Radix Scutellariae 90g Olibanum 45g Myrrha 75g
Radix Angelicae Dahuricae 90g Rhizoma Polygoni Cuspidati 100g Herba Taraxaci 60g Fructus Forsythiae 90g
Flos Lonicerae 80g Pericarpium Citri Reticulatae 105g Fructus Aurantii 60g Poria 130g
Its preparation method is:
(1) each pulverizing medicinal materials is become coarse powder, mix, decoct with water each 1 hour 3 times;
(2) decocting liquid filters, and merging filtrate left standstill 6 hours;
The supernatant of (3) leaching (2), and being concentrated into 70 ℃ of heat, to survey relative densities be 1.36 thick paste, standby;
(4) with the thick paste that makes, drying is pulverized, and adds the about 146g of mixture of starch and dextrin (ratio is 4: 1), and mixing is made granule with 75% ethanol, and drying is standby;
(5) in flakes, promptly with dried granule compacting.
Embodiment 2:
Adopt following drug regimen:
Radix Astragali 75g Radix Scutellariae 110g Olibanum 50g Myrrha 100g
Radix Angelicae Dahuricae 120g Rhizoma Polygoni Cuspidati 120g Herba Taraxaci 80g Fructus Forsythiae 110g
Flos Lonicerae 100g Pericarpium Citri Reticulatae 140g Fructus Aurantii 80g Poria 170g
Its preparation method is:
(1) each pulverizing medicinal materials is become coarse powder, mix, decoct with water each 1 hour 4 times;
(2) decocting liquid filters, and merging filtrate left standstill 8 hours;
The supernatant of (3) leaching (2), and being concentrated into 80 ℃ of heat, to survey relative densities be 1.34 thick paste, standby;
(4) with the thick paste that makes, drying is pulverized, and adds the about 186g of starch, mixing, and water is made granule, adds 1% magnesium stearate, mixing, drying, standby;
(5) in flakes, promptly with dried granule compacting.
Embodiment 3:
Adopt following drug regimen:
Radix Astragali 35g Radix Scutellariae 50g Olibanum 40g Myrrha 50g
Radix Angelicae Dahuricae 60g Rhizoma Polygoni Cuspidati 50g Herba Taraxaci 30g Fructus Forsythiae 70g
Flos Lonicerae 60g Pericarpium Citri Reticulatae 65g Fructus Aurantii 40g Poria 80g
Its preparation method is:
(1) each pulverizing medicinal materials is become coarse powder, mix, decoct with water each 1 hour 2 times;
(2) decocting liquid filters, and merging filtrate left standstill 4 hours;
The supernatant of (3) leaching (2), and being concentrated into 60 ℃ of heat, to survey relative densities be 1.38 thick paste, standby;
(4) with the thick paste that makes, drying is pulverized, and adds the about 25g of lactose, and the about 48g of dextrin makes granule with 90% ethanol, and drying is standby;
(5) in flakes, promptly with dried granule compacting.
Claims (4)
1. pharmaceutical composition that is used for the treatment of chronic cholecystitis is characterized in that it is that raw material is formed by following parts by weight of Chinese traditional medicine material:
Radix Astragali 30-80 part Radix Scutellariae 50-120 part Olibanum 30-60 part Myrrha 50-100 part
Radix Angelicae Dahuricae 60-120 part Rhizoma Polygoni Cuspidati 50-140 part Herba Taraxaci 30-90 part Fructus Forsythiae 60-120 part
Flos Lonicerae 50-100 part Pericarpium Citri Reticulatae 60-150 part Fructus Aurantii 40-80 part Poria 70-180 part.
2. a kind of pharmaceutical composition that is used for the treatment of chronic cholecystitis according to claim 1, wherein the weight portion proportioning of each Chinese crude drug raw material is:
75 parts of 45 parts of Myrrhas of 90 parts of Olibanums of 60 parts of Radix Scutellariaes of the Radix Astragali
90 parts of 60 parts of Fructus Forsythiaes of 100 parts of Herba Taraxacis of 90 parts of Rhizoma Polygoni Cuspidati of the Radix Angelicae Dahuricae
130 parts in 60 parts of Poria of 105 parts of Fructus Aurantiis of 80 parts of Pericarpium Citri Reticulataes of Flos Lonicerae.
3. according to each described a kind of pharmaceutical composition that is used for the treatment of chronic cholecystitis of claim 1-2, its preparation method is:
(1) each pulverizing medicinal materials is become coarse powder, mix, decoct with water each 1～3 hour 2～4 times;
(2) decocting liquid filters, and merging filtrate left standstill 4～8 hours;
The supernatant of (3) leaching (2), and being concentrated into 60～80 ℃ of heat, to survey relative densities be 1.33～1.38 thick paste, standby;
(4) with the thick paste that makes, drying is pulverized, and adds conventional auxiliary materials and mixing, and water or Different concentrations of alcohol are made granule, and drying is standby;
(5) in flakes, promptly with dried granule compacting.
4. according to each described a kind of pharmaceutical composition that is used for the treatment of chronic cholecystitis of claim 1-2, its function cures mainly and is: have the function of depressed liver-energy dispersing and function of gallbladder promoting, removing damp-heat, anti-inflammatory analgetic, cure mainly chronic cholecystitis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810240675A CN101766718A (en) | 2008-12-26 | 2008-12-26 | Drug combination for treating chronic cholecystitis and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810240675A CN101766718A (en) | 2008-12-26 | 2008-12-26 | Drug combination for treating chronic cholecystitis and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101766718A true CN101766718A (en) | 2010-07-07 |
Family
ID=42499919
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200810240675A Pending CN101766718A (en) | 2008-12-26 | 2008-12-26 | Drug combination for treating chronic cholecystitis and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101766718A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102357215A (en) * | 2011-11-16 | 2012-02-22 | 河南中医学院 | Ointment for treating right hypochondriac distention and pain caused by acute and chronic cholecystitis |
| CN104771700A (en) * | 2015-04-22 | 2015-07-15 | 王玉玲 | Traditional Chinese medicine preparation for treating chronic cholecystitis and preparation method thereof |
-
2008
- 2008-12-26 CN CN200810240675A patent/CN101766718A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102357215A (en) * | 2011-11-16 | 2012-02-22 | 河南中医学院 | Ointment for treating right hypochondriac distention and pain caused by acute and chronic cholecystitis |
| CN102357215B (en) * | 2011-11-16 | 2013-01-02 | 河南中医学院 | Ointment for treating right hypochondriac distention and pain caused by acute and chronic cholecystitis |
| CN104771700A (en) * | 2015-04-22 | 2015-07-15 | 王玉玲 | Traditional Chinese medicine preparation for treating chronic cholecystitis and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101632750B (en) | Chinese medicinal composition for replenishing essence, filling marrow, boosting kidney and strengthening yang and preparation method thereof | |
| CN104523865A (en) | Medicine for treating breast diseases | |
| CN100579562C (en) | Oral Chinese medicine composition for treating constipation | |
| CN103169883B (en) | Traditional Chinese medicine for treating infantile jaundice | |
| CN101664524A (en) | Medicament for treating paranasal sinusitis and preparation method thereof | |
| CN103877508A (en) | Traditional Chinese medicine composition for treating metrocarcinoma | |
| CN103394002B (en) | Medicinal composition for treating cutaneous pruritus as well as preparation method and application thereof | |
| CN101766718A (en) | Drug combination for treating chronic cholecystitis and preparation method thereof | |
| CN102327395B (en) | Pharmaceutical composition for treating postpartum persistent lochia and preparation method thereof | |
| CN104825785A (en) | TCM (traditional Chinese medicine) composition for treating hyperplasia of mammary glands | |
| CN102205068B (en) | Medicament for treating chronic ulcerative colitis and preparation method thereof | |
| CN103623196B (en) | Traditional Chinese medicine composition for treating yin-deficiency and fire-excess type periodontitis | |
| CN101732469B (en) | Application of Chinese medicinal composition in preparation of medicament for treating aphonia | |
| CN101279070A (en) | Medicament composite for warming kidney and promoting blood circulation, and dredging channels and collaterals, and method of preparing the same | |
| CN1111065C (en) | Plaster for curing mastosis | |
| CN102973899B (en) | Traditional Chinese medicine composition for treating cholelithiasis | |
| CN108403974B (en) | Traditional Chinese medicine composition for treating calculus | |
| CN102240384B (en) | Medicament for treating phlegm-stasis accumulating type epilepsy and preparation method thereof | |
| CN100444877C (en) | A Chinese medicine for treating cholecystitis | |
| CN101773643B (en) | Chinese medicine preparation for treating mammary gland proliferation diseases and preparation method thereof | |
| CN101167915B (en) | Traditional Chinese medicine for treating chronic superficial gastritis and its preparation method | |
| CN105412244A (en) | Traditional Chinese medicine composition treating gynecological cervicitis | |
| CN105169199A (en) | Traditional Chinese medicinal composition for treating functional dyspepsia with syndrome of liver-stomach disharmony | |
| CN106138686A (en) | A kind of Chinese medicine preparation treating goiter and tumor in early days | |
| CN104510835A (en) | Traditional Chinese medicinal formula for treating intestinal tumor |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20100707 |