CN101757509A - Traditional Chinese medicine composition for treating icterohepatitis and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating icterohepatitis and preparation method thereof Download PDF

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CN101757509A
CN101757509A CN200910309265A CN200910309265A CN101757509A CN 101757509 A CN101757509 A CN 101757509A CN 200910309265 A CN200910309265 A CN 200910309265A CN 200910309265 A CN200910309265 A CN 200910309265A CN 101757509 A CN101757509 A CN 101757509A
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radix
chinese medicine
herba
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CN101757509B (en
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王峰
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Taiyi Hepu Beijing Research Institute of Traditional Chinese Medicine Co Ltd
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Taiyi Hepu Beijing Research Institute of Traditional Chinese Medicine Co Ltd
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Abstract

The invention discloses a traditional Chinese medicine composition for treating icterohepatitis and a preparation method thereof. The traditional Chinese medicine composition mainly comprises the following Chinese medicinal herbs: stem of capillary sagebrush, coptis, kudzu-vine root, honeysuckle flower, chrysanthemum, gypsum, rhizoma anemarrhenae, radix bupleuri, gardenia, isatis root, dyer woad leaf, cordate houttuynia, redroot gromwell root, radix geutianae, radix sophorae flavescentis, ash bark, rheum officinale, antelope's horn, folium mori, poria cocos, talcum, rhizoma alismatis, semen plantaginis, herba lysimachiae, rhizoma cyperi, wrinkled giant hyssop, rhizoma atractylodis, officinal magnolia bark, rosewood heart wood, pangolin, agilawood, baical skullcap root, taraxacum officinale root, herba violae and radix scrophulariae. The traditional Chinese medicine composition can be prepared into any one common oral preparation according to the conventional traditional Chinese medicine preparation method. The invention can remarkably improve the symptoms of jaundice, strength lacking, anorexia, nausea and vomiting, liver distending pain, abdominal distension, constipation or diarrhea, skin itch, liver polycystic swelling, compact texture and pressing pain, rap pain, dysfunction of liver and the like caused by the icterohepatitis. Because the traditional Chinese medicine composition is combined by adopting medicinal and edible medicinal herbs specified in the Nation Formulary basically, the invention has the advantages of low cost, no toxic or side effect and the like.

Description

A kind of Chinese medicine composition for the treatment of the icterohepatitis disease and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of the icterohepatitis disease.Relating in particular to a kind of is the Chinese medicine composition and preparation method thereof of the treatment icterohepatitis disease of crude drug with the Chinese herbal medicine.
Background technology
Do not note the diet health, contact the generation that factors such as the trouble patient of this disease and some iatrogenic infections all can cause the icterohepatitis disease, main clinical manifestation for feel sick, hepatalgia, inappetence, jaundice, liver function test are unusual etc.As not controlled timely and effectively and being treated, to produce infringement greatly to liver function, as: liver organization hyperemia, edema take place, ooze out, a series of variations such as hepatocellular degeneration and necrosis, severe patient causes bilirubin encephalopathy or threat to life, and the clinical onset rate has the trend of continuous rising in recent years.
Clinically icterohepatitis still there is not clear and definite therapeutic scheme, modern medicine is at clinical a certain symptom treatment, often fall flat, can not find suitable Therapeutic Method, in order to overcome above-mentioned defective, the present invention is based on the differential diagnosis of diseases and the dialectical principle that combines of Chinese traditional treatment icterohepatitis disease, treating both the principal and secondary aspects of a disease, deficiency and excess is also controlled, inside and outside logical the accent, emergency is taken in concurrently, filters out the natural plant of antiinflammatory dampness removing, heat-clearing and toxic substances removing, depressed liver-energy dispersing and function of gallbladder promoting, according to the theory of Chinese medical science prescription, be prepared from according to certain weight proportion.A kind of Chinese medicine composition of evident in efficacy, with low cost, treatment icterohepatitis disease that toxic and side effects is minimum is provided.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage forms, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be: pill, capsule, tablet, powder, granule or oral liquid etc.
Summary of the invention
Technical problem to be solved by this invention is assorted to overcome above-described shortcoming, and a kind of Chinese medicine composition of treatment icterohepatitis disease of evident in efficacy, with low cost, almost non-toxic side effect is provided.
The technical problem of the desired solution of the present invention realizes by following technological approaches.
A kind of Chinese medicine composition for the treatment of the icterohepatitis disease of the present invention, the component of main following weight portion is formed:
Herba Artemisiae Scopariae 1~50 gram, Rhizoma Coptidis 1~30 gram, Radix Puerariae 1~50 gram, Flos Lonicerae 1~50 gram, Flos Chrysanthemi 1~40 gram, Gypsum Fibrosum 1~50 gram, the Rhizoma Anemarrhenae 1~40 gram, Radix Bupleuri 1~40 gram, Fructus Gardeniae 1~30 gram, Radix Isatidis 1~40 gram, Folium Isatidis 1~40 gram, Herba Houttuyniae 1~50 gram, Herba Artemisiae Annuae 1~30 gram, Herba Lophatheri 1~40 gram, Radix Arnebiae (Radix Lithospermi) 1~40 gram, Radix Gentianae 1~50 gram, Radix Sophorae Flavescentis 1~40 gram, Cortex Fraxini 1~40 gram, Radix Et Rhizoma Rhei 1~30 gram, Cornu Saigae Tataricae 1~20 gram, Folium Mori 1~40 gram, Pericarpium Citri Reticulatae Viride 1~50 gram, Poria 1~50 gram, Talcum 1~40 gram, Massa Medicata Fermentata 1~40 gram, Fructus Crataegi 1~40 gram, Rhizoma Alismatis 1~40 gram, Semen Plantaginis 1~30 gram, Herba Lysimachiae 1~40 gram, Semen Coicis 1~30 gram.
Be preferably:
Herba Artemisiae Scopariae 30 grams, Rhizoma Coptidis 20 grams, Radix Puerariae 30 grams, Flos Lonicerae 30 grams, Flos Chrysanthemi 15 grams, Gypsum Fibrosum 30 grams, the Rhizoma Anemarrhenae 30 grams, Radix Bupleuri 30 grams, Fructus Gardeniae 20 grams, Radix Isatidis 30 grams, Folium Isatidis 20 grams, Herba Houttuyniae 20 grams, Herba Artemisiae Annuae 15 grams, Herba Lophatheri 30 grams, Radix Arnebiae (Radix Lithospermi) 20 grams, Radix Gentianae 30 grams, Radix Sophorae Flavescentis 20 grams, Cortex Fraxini 15 grams, Radix Et Rhizoma Rhei 15 grams, Cornu Saigae Tataricae 6 grams, Folium Mori 20 grams, Pericarpium Citri Reticulatae Viride 20 grams, Poria 30 grams, Talcum 20 grams, Massa Medicata Fermentata 30 grams, Fructus Crataegi 15 grams, Rhizoma Alismatis 20 grams, Semen Plantaginis 20 grams, Herba Lysimachiae 20 grams, Semen Coicis 20 grams.
The weight portion consumption of each component of Chinese medicine composition of the present invention can also be:
Rhizoma Cyperi 1~50 gram, the Radix Aucklandiae 1~40 gram, Herba Pogostemonis 1~40 gram, Folium Perillae 1~40 gram, Rhizoma Atractylodis 1~30 gram, Cortex Magnoliae Officinalis 1~40 gram, Fructus Toosendan 1~40 gram, Lignum Dalbergiae Odoriferae 1~30 gram, Squama Manis 1~20 gram, Lignum Aquilariae Resinatum 1~20 gram, Fructus Amomi 1~20 gram, Radix Scutellariae 1~40 gram, Cortex Lycii 1~50 gram, Herba Taraxaci 1~40 gram, Herba Violae 1~40 gram, Radix Sophorae Tonkinensis 1~50 gram, Fructus Arctii 1~40 gram, Radix Scrophulariae 1~40 gram.
Be preferably:
Rhizoma Cyperi 30 grams, the Radix Aucklandiae 30 grams, Herba Pogostemonis 20 grams, Folium Perillae 20 grams, Rhizoma Atractylodis 20 grams, Cortex Magnoliae Officinalis 20 grams, Fructus Toosendan 30 grams, Lignum Dalbergiae Odoriferae 15 grams, Squama Manis 10 grams, Lignum Aquilariae Resinatum 5 grams, Fructus Amomi 15 grams, Radix Scutellariae 20 grams, Cortex Lycii 30 grams, Herba Taraxaci 30 grams, Herba Violae 25 grams, Radix Sophorae Tonkinensis 30 grams, Fructus Arctii 30 grams, Radix Scrophulariae 20 grams.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage form, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be pill, capsule, tablet, powder, granule or oral liquid etc.
Chinese medicine composition of the present invention is opened one's minds based on traditional Chinese medical science the five internal organs differentiation of syndromes of YIN and YANG guiding principle, in conjunction with safe one and Pu innovation theory system " ten thousand diseases ascent theory ", " the five internal organs differentiation of syndromes of YIN and YANG guiding principle ", " three-dimensional conservation regulation and control rule " and clinical treatment " pairing principle " are as instructing, take place in conjunction with disease, development and the rule that changes, classify according to the original new drug system, formation is monarch with " the five internal organs basic function is adjusted; equilibrium between yin and yang coordination side ", " the main pathogenesis of the five internal organs adjustment side " is minister, " therapy of serious disease side " is assistant, " clinical fundamental symptoms symptomatic treatment side " Chinese medicine patent medicine " original new drug system " for making.This is the important content of Thailand one and Pu (Beijing) Chinese medicine academy patent strategy.
The structure of Thailand one and Pu patent strategy is convenient to Chinese medicine and is realized standardization, scale, industrialization, modernization and industrialization.For traditional Chinese medicine development has been opened up a road that meets the Chinese medicine self-law with innovation.The used herbal raw material medicine of the present invention all can be buied from the Chinese medicine shop, and its specification meets national medical standard.
Usage and dosage: dosage of the present invention depends on concrete dosage form, factors such as patient age, body weight, health status.As guidance: for oral administration: 1) capsule: obey 2~5 every day three times at every turn, every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2~4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.
The treatment that the present invention is directed to icterohepatitis disease patient is very effective, various crude drug are coordinated mutually can play together and are at utmost brought into play drug effect, can effectively improve the self-coordination ability of patient's body, significantly improve function and clinical subjective symptoms, have advantage such as have no side effect, expense is lower in addition.
The specific embodiment
Further describe the present invention by the following examples, it should be understood that these embodiment only are used for the purpose of illustration, never are limited to the present invention.
The preparation of [embodiment 1] capsule
Take by weighing each raw material by following weight portion: Herba Artemisiae Scopariae 30 grams, Rhizoma Coptidis 20 grams, Radix Puerariae 30 grams, Flos Lonicerae 30 grams, Flos Chrysanthemi 15 grams, Gypsum Fibrosum 30 grams, the Rhizoma Anemarrhenae 30 grams, Radix Bupleuri 30 grams, Fructus Gardeniae 20 grams, Radix Isatidis 30 grams, Folium Isatidis 20 grams, Herba Houttuyniae 20 grams, Herba Artemisiae Annuae 15 grams, Herba Lophatheri 30 grams, Radix Arnebiae (Radix Lithospermi) 20 grams, Radix Gentianae 30 grams, Radix Sophorae Flavescentis 20 grams, Cortex Fraxini 15 grams, Radix Et Rhizoma Rhei 15 grams, Cornu Saigae Tataricae 6 grams, Folium Mori 20 grams, Pericarpium Citri Reticulatae Viride 20 grams, Poria 30 grams, Talcum 20 grams, Massa Medicata Fermentata 30 grams, Fructus Crataegi 15 grams, Rhizoma Alismatis 20 grams, Semen Plantaginis 20 grams, Herba Lysimachiae 20 grams, Semen Coicis 20 grams, Rhizoma Cyperi 30 grams, the Radix Aucklandiae 30 grams, Herba Pogostemonis 20 grams, Folium Perillae 20 grams, Rhizoma Atractylodis 20 grams, Cortex Magnoliae Officinalis 20 grams, Fructus Toosendan 30 grams, Lignum Dalbergiae Odoriferae 15 grams, Squama Manis 10 grams, Lignum Aquilariae Resinatum 5 grams, Fructus Amomi 15 grams, Radix Scutellariae 20 grams, Cortex Lycii 30 grams, Herba Taraxaci 30 grams, Herba Violae 25 grams, Radix Sophorae Tonkinensis 30 grams, Fructus Arctii 30 grams, Radix Scrophulariae 20 grams.
Grind into after each component mixing with above-mentioned weight and incapsulate promptly after fine powder is crossed 1500 mesh sieves.
The preparation of [embodiment 2] granule
Take by weighing each raw material by following weight portion: Herba Artemisiae Scopariae 30 grams, Rhizoma Coptidis 20 grams, Radix Puerariae 30 grams, Flos Lonicerae 30 grams, Flos Chrysanthemi 15 grams, Gypsum Fibrosum 30 grams, the Rhizoma Anemarrhenae 30 grams, Radix Bupleuri 30 grams, Fructus Gardeniae 20 grams, Radix Isatidis 30 grams, Folium Isatidis 20 grams, Herba Houttuyniae 20 grams, Herba Artemisiae Annuae 15 grams, Herba Lophatheri 30 grams, Radix Arnebiae (Radix Lithospermi) 20 grams, Radix Gentianae 30 grams, Radix Sophorae Flavescentis 20 grams, Cortex Fraxini 15 grams, Radix Et Rhizoma Rhei 15 grams, Cornu Saigae Tataricae 6 grams, Folium Mori 20 grams, Pericarpium Citri Reticulatae Viride 20 grams, Poria 30 grams, Talcum 20 grams, Massa Medicata Fermentata 30 grams, Fructus Crataegi 15 grams, Rhizoma Alismatis 20 grams, Semen Plantaginis 20 grams, Herba Lysimachiae 20 grams, Semen Coicis 20 grams, Rhizoma Cyperi 30 grams, the Radix Aucklandiae 30 grams, Herba Pogostemonis 20 grams, Folium Perillae 20 grams, Rhizoma Atractylodis 20 grams, Cortex Magnoliae Officinalis 20 grams, Fructus Toosendan 30 grams, Lignum Dalbergiae Odoriferae 15 grams, Squama Manis 10 grams, Lignum Aquilariae Resinatum 5 grams, Fructus Amomi 15 grams, Radix Scutellariae 20 grams, Cortex Lycii 30 grams, Herba Taraxaci 30 grams, Herba Violae 25 grams, Radix Sophorae Tonkinensis 30 grams, Fructus Arctii 30 grams, Radix Scrophulariae 20 grams.
Each raw material of above-mentioned weight fraction is mixed, after grinding into fine powder and crossing 1500 mesh sieves, add ethanol and make adhesive, add starch and do filler, be pressed into granule.
The preparation of [embodiment 3] tablet
Take by weighing each raw material according to following weight portion: Herba Artemisiae Scopariae 30 grams, Rhizoma Coptidis 20 grams, Radix Puerariae 30 grams, Flos Lonicerae 30 grams, Flos Chrysanthemi 15 grams, Gypsum Fibrosum 30 grams, the Rhizoma Anemarrhenae 30 grams, Radix Bupleuri 30 grams, Fructus Gardeniae 20 grams, Radix Isatidis 30 grams, Folium Isatidis 20 grams, Herba Houttuyniae 20 grams, Herba Artemisiae Annuae 15 grams, Herba Lophatheri 30 grams, Radix Arnebiae (Radix Lithospermi) 20 grams, Radix Gentianae 30 grams, Radix Sophorae Flavescentis 20 grams, Cortex Fraxini 15 grams, Radix Et Rhizoma Rhei 15 grams, Cornu Saigae Tataricae 6 grams, Folium Mori 20 grams, Pericarpium Citri Reticulatae Viride 20 grams, Poria 30 grams, Talcum 20 grams, Massa Medicata Fermentata 30 grams, Fructus Crataegi 15 grams, Rhizoma Alismatis 20 grams, Semen Plantaginis 20 grams, Herba Lysimachiae 20 grams, Semen Coicis 20 grams, Rhizoma Cyperi 30 grams, the Radix Aucklandiae 30 grams, Herba Pogostemonis 20 grams, Folium Perillae 20 grams, Rhizoma Atractylodis 20 grams, Cortex Magnoliae Officinalis 20 grams, Fructus Toosendan 30 grams, Lignum Dalbergiae Odoriferae 15 grams, Squama Manis 10 grams, Lignum Aquilariae Resinatum 5 grams, Fructus Amomi 15 grams, Radix Scutellariae 20 grams, Cortex Lycii 30 grams, Herba Taraxaci 30 grams, Herba Violae 25 grams, Radix Sophorae Tonkinensis 30 grams, Fructus Arctii 30 grams, Radix Scrophulariae 20 grams.
Each raw material of above-mentioned weight portion is mixed, after grinding into fine powder and crossing 800~1200 order dusting covers, make tablet promptly.
The preparation of [embodiment 4] pill
Take by weighing each raw material according to following weight portion: Herba Artemisiae Scopariae 30 grams, Rhizoma Coptidis 20 grams, Radix Puerariae 30 grams, Flos Lonicerae 30 grams, Flos Chrysanthemi 15 grams, Gypsum Fibrosum 30 grams, the Rhizoma Anemarrhenae 30 grams, Radix Bupleuri 30 grams, Fructus Gardeniae 20 grams, Radix Isatidis 30 grams, Folium Isatidis 20 grams, Herba Houttuyniae 20 grams, Herba Artemisiae Annuae 15 grams, Herba Lophatheri 30 grams, Radix Arnebiae (Radix Lithospermi) 20 grams, Radix Gentianae 30 grams, Radix Sophorae Flavescentis 20 grams, Cortex Fraxini 15 grams, Radix Et Rhizoma Rhei 15 grams, Cornu Saigae Tataricae 6 grams, Folium Mori 20 grams, Pericarpium Citri Reticulatae Viride 20 grams, Poria 30 grams, Talcum 20 grams, Massa Medicata Fermentata 30 grams, Fructus Crataegi 15 grams, Rhizoma Alismatis 20 grams, Semen Plantaginis 20 grams, Herba Lysimachiae 20 grams, Semen Coicis 20 grams, Rhizoma Cyperi 30 grams, the Radix Aucklandiae 30 grams, Herba Pogostemonis 20 grams, Folium Perillae 20 grams, Rhizoma Atractylodis 20 grams, Cortex Magnoliae Officinalis 20 grams, Fructus Toosendan 30 grams, Lignum Dalbergiae Odoriferae 15 grams, Squama Manis 10 grams, Lignum Aquilariae Resinatum 5 grams, Fructus Amomi 15 grams, Radix Scutellariae 20 grams, Cortex Lycii 30 grams, Herba Taraxaci 30 grams, Herba Violae 25 grams, Radix Sophorae Tonkinensis 30 grams, Fructus Arctii 30 grams, Radix Scrophulariae 20 grams.
Each raw material of above-mentioned weight is mixed, grind into cross 600~1000 mesh sieves behind the fine powder after, make pill promptly.
The preparation of [embodiment 5] oral liquid
Take by weighing each raw material according to following weight portion: Herba Artemisiae Scopariae 30 grams, Rhizoma Coptidis 20 grams, Radix Puerariae 30 grams, Flos Lonicerae 30 grams, Flos Chrysanthemi 15 grams, Gypsum Fibrosum 30 grams, the Rhizoma Anemarrhenae 30 grams, Radix Bupleuri 30 grams, Fructus Gardeniae 20 grams, Radix Isatidis 30 grams, Folium Isatidis 20 grams, Herba Houttuyniae 20 grams, Herba Artemisiae Annuae 15 grams, Herba Lophatheri 30 grams, Radix Arnebiae (Radix Lithospermi) 20 grams, Radix Gentianae 30 grams, Radix Sophorae Flavescentis 20 grams, Cortex Fraxini 15 grams, Radix Et Rhizoma Rhei 15 grams, Cornu Saigae Tataricae 6 grams, Folium Mori 20 grams, Pericarpium Citri Reticulatae Viride 20 grams, Poria 30 grams, Talcum 20 grams, Massa Medicata Fermentata 30 grams, Fructus Crataegi 15 grams, Rhizoma Alismatis 20 grams, Semen Plantaginis 20 grams, Herba Lysimachiae 20 grams, Semen Coicis 20 grams, Rhizoma Cyperi 30 grams, the Radix Aucklandiae 30 grams, Herba Pogostemonis 20 grams, Folium Perillae 20 grams, Rhizoma Atractylodis 20 grams, Cortex Magnoliae Officinalis 20 grams, Fructus Toosendan 30 grams, Lignum Dalbergiae Odoriferae 15 grams, Squama Manis 10 grams, Lignum Aquilariae Resinatum 5 grams, Fructus Amomi 15 grams, Radix Scutellariae 20 grams, Cortex Lycii 30 grams, Herba Taraxaci 30 grams, Herba Violae 25 grams, Radix Sophorae Tonkinensis 30 grams, Fructus Arctii 30 grams, Radix Scrophulariae 20 grams.
Each raw material of above-mentioned weight is mixed, after three decoctions, three filtrates are mixed, filter, be concentrated into rule
Fixed concentration, put cold, the stock solution embedding, irradiation sterilization, after the check, packed products is made oral liquid promptly.
[experimental example] traditional Chinese medicine composition for treating icterohepatitis of the present invention disease patient's clinical observation on the therapeutic effect experiment
One, the physical data of experimental subject: adopt Chinese medicine composition of the present invention to treat 216 routine patients altogether, wherein male 157 examples, women 59 examples; The oldest person 69 years old, the age reckling has only 4 years old.
Therapeutic Method:
Usage and dosage: adopt the prepared medicament of the embodiment of the invention, its usage and consumption are as follows: 1) capsule: obey 2~5 every day three times at every turn, and every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2~4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.
The course of treatment: one month is a course of treatment, treats for 3 courses of treatment altogether.
The therapeutic evaluation standard
Cure: sign is improved fully, and liver function recovery is normal, and the patient does not have any bad sensation, and is happy, in high spirits.
Produce effects: sign is significantly improved, and liver function is recovered normally substantially, and the patient does not have bad sensation substantially, and is happy, and spirit is fine.
Effectively: sign obviously changes, and liver function is significantly recovered, and random thoughts have discomfort slightly, but can accept, and mood is better, and energy is more abundant.
Invalid: sign does not have any change, and liver function does not have change, and symptom such as preceding feels depressed, and lethargy is depressed.
Model case:
1, Deng, man, 38 years old, canvasser.
The patient began to find icteric sclera, yellowish body, yellow urine before more than four months, accompany tired, poor appetite, right side side of body portion pain, xanthochromia is deepened rapidly, and symptom exacerbates day by day, be diagnosed as icterohepatitis, after with two medicines (just be hepatinica, then add use hormone) treatment, 1 wheat harvesting period, the state of an illness once once took a turn for the better, jaundice disappears substantially, and transhydrogenase is reduced to 180d by 760d in the paddy.But the state of an illness increased the weight of again afterwards.See symptom aggravations such as jaundice is deepened, tired, pain in the right hypochondrium, stomach is received extreme difference, and liver function test prompting hepatic injury increases the weight of the hormone of stopping using before a week.Take Chinese medicine composition of the present invention after 5 days, jaundice day by day disappears, pain relief, continuous clothes Chinese medicine composition of the present invention 10 days, jaundice disappears substantially, and spirit is gradually shaken, and symptom is greatly taken on a new look, transhydrogenase is by 60d in the chemical examination paddy, obeyed Chinese medicine composition of the present invention again 20, symptom all disappears, and blood drawing chemical examination liver function is normal, the patient disease recovery from illness
2, check certain, man, 32 years old, workman.
The patient has the hepatitis contact history.1 week came, conscious nauseating, inappetence, and fatigue and weak, the liver pain discomfort, urine color such as black tea, stool still can.Sclera, the slight xanthochromia of skin, abdominal part is flat soft, 3cm under the liver rib, quality is slightly blunt to be had and touches a tender spot and percussion pain, does not reach yellow and thin fur, stringy pulse decimal under the spleen rib.Liver function test: glutamate pyruvate transaminase 320d, thymol turbidity test 8d, sulphuric acid turbidity test 12d, the red matter 4.2d of gallbladder.Take Chinese medicine composition of the present invention after 3 days, spirit takes a turn for the better, sclera, xanthochromia day by day disappear, and hepatalgia is greatly alleviated, continuous clothes Chinese medicine composition of the present invention 7 days, jaundice disappears, chemical examination glutamate pyruvate transaminase 30d, thymol turbidity test 5d, sulphuric acid turbidity test 9d, the red matter 0.8d of gallbladder, liver function test is all normal.
3, Lee so-and-so, woman, 22 years old, student.
Sclera, xanthochromia 2 days appear in the sky surplus the limb soft weak 10, anorexia, and colour cast is red, yellow and greasy fur, stringy and rolling pulse.Liver function test prompting: icteric index 50U, the quantitative 106.02 μ mol/L of bilirubin, glutamate pyruvate transaminase>1000U.Take Chinese medicine composition of the present invention after 3 days, spirit takes a turn for the better, sclera, xanthochromia obviously disappear, continuous clothes Chinese medicine composition of the present invention 5 days, chemical examination: icteric index 15U, the quantitative 37.62 μ mol/L of bilirubin, glutamate pyruvate transaminase 370U, continuous clothes Chinese medicine composition of the present invention 25 days, liver function test is all normal.
4, Shao, man, 10 years old.
Patient does not have inducement appearance heating before 8 days, body temperature fluctuates in 37.6~38.7 ℃, occurs malaise simultaneously, and Sleep hyperhidrosis is obvious, before 5 days, (gastric content) appears feeling sick, vomits in patient, abdominal discomfort, full abdomen dull pain, yellowish urine, be Umber,, take that Western medicine is invalid examined afterwards with skin pruritus.Take Chinese medicine composition of the present invention after 1 week, temperature recovery is normal, and symptom is greatly taken on a new look, and in continuous clothes 3 weeks of Chinese medicine composition of the present invention, urine is normal, and surplus disease all disappears.After 2 months, energetic, liver function test is all normal.
5, Zeng, woman, 39 years old, teacher.
Occur together heat 2 days of unable 10 days of anorexia companion xanthochromia, patient's readme: mouthful sticking bitter taste, desire drink, the time right side of body portion dull pain discomfort is arranged, the nausea of feeling sick, yellow urine, fatigue and weak, the liver function result of laboratory test shows: acute icterohepatitisshock, red tongue tongue are greasy in vain, slippery and rapid pulse.Take Chinese medicine composition of the present invention after 3 days, heating is decorporated, sclera, xanthochromia is clearly better, uncomfortable basic disappearance of right side of body portion's dull pain, continuous clothes Chinese medicine composition of the present invention 7 days, xanthochromia and transference cure, uncomfortable basic disappearance of right side of body portion's dull pain, symptom is greatly taken on a new look, and obeys Chinese medicine composition of the present invention again 50, and blood drawing chemical examination liver function is normal, the patient disease recovery from illness is gone back with satisfaction.
6, Zhao, man, 9 years old.
Eye Huang, yellowish urine 15 days, the infant premorbid has clearly goes up the sense history, once took Roxithromycin, ribavirin, Ceftriaxone 3~4 days, after 1 week jaundice appears, the heat that occurs together 2~3 days, about 38.4 ℃ of body temperature, poor appetite, weak, abdominal distention, private prosecution has the white pottery soil sample just, and complexion is dark slightly, whole skin mucosa severe xanthochromia.Take Chinese medicine composition of the present invention after 3 days, heating, sclera, xanthochromia take a turn for the better gradually, receive to increase, continuous clothes Chinese medicine composition of the present invention 7 days, and heating is decorporated, and symptom is greatly taken on a new look, and obeys Chinese medicine composition of the present invention again after 50 days, and above-mentioned symptom all disappears.
7, the side so-and-so, the man, 48 years old, manager.
Patient's 2 week pain in the hepatic region, the poor appetite of feeling sick, the abdominal distention loose stool, urinate as strong tea the liver function test result: glutamate pyruvate transaminase 520U, icteric index 34U, the quantitative 90.68 μ mol/L of bilirubin, stringy pulse, light red tongue, tongue is white, sclera and xanthochromia.Take Chinese medicine composition of the present invention after 3 days, jaundice symptom greatly alleviates, continuous clothes Chinese medicine composition of the present invention 5 days, and surplus disease is gradually removed, and receives to increase, and obeys Chinese medicine composition of the present invention again 7, and symptom continues to improve.After 2 months, the check liver function: glutamate pyruvate transaminase 28d, icteric index 5d, the quantitative 15.2 μ mol/L of bilirubin all recover normal.
8, Pan so-and-so, woman, 37 years old, peasant.
The patient is conscious heating before 10 days, began to occur eyes and body skin xanthochromia before 1 week, thirsty but drink water seldom, the bitter taste mouth is sticking, the urine yellow skin is red, rare when doing during stool, red tongue, tongue is greasy in vain, slippery and rapid pulse, be diagnosed as through liver function test: icterohepatitis, the week of once being in hospital adopts Chinese medicine and western medicine symptomatic treatment effect all not obvious, and went to a doctor in here afterwards.Take Chinese medicine composition of the present invention after 5 days, patient's heating, jaundice disappear gradually, continuous clothes Chinese medicine composition of the present invention 10 days, jaundice disappears, two just basic recoveries normally, and symptom is significantly improved, obeyed Chinese medicine composition of the present invention again 45, above-mentioned symptom all disappears, and is normal through the chemical examination liver function, patient's recovery from illness.
Five, therapeutic outcome:
In the 216 routine cases of being accepted for medical treatment,, wherein cure 139 examples through treatment in 3 months, produce effects 38 examples, effective 39 examples, invalid 0 example, total effective rate reaches 100%.The result shows that Chinese medicine composition of the present invention has extremely significant curative effect to treatment icterohepatitis disease patient.

Claims (7)

1. Chinese medicine composition for the treatment of the icterohepatitis disease is characterized in that: mainly contain following bulk drugs and form:
Herba Artemisiae Scopariae 1~50 gram, Rhizoma Coptidis 1~30 gram, Radix Puerariae 1~50 gram, Flos Lonicerae 1~50 gram, Flos Chrysanthemi 1~40 gram, Gypsum Fibrosum 1~50 gram, the Rhizoma Anemarrhenae 1~40 gram, Radix Bupleuri 1~40 gram, Fructus Gardeniae 1~30 gram, Radix Isatidis 1~40 gram, Folium Isatidis 1~40 gram, Herba Houttuyniae 1~50 gram, Herba Artemisiae Annuae 1~30 gram, Herba Lophatheri 1~40 gram, Radix Arnebiae (Radix Lithospermi) 1~40 gram, Radix Gentianae 1~50 gram, Radix Sophorae Flavescentis 1~40 gram, Cortex Fraxini 1~40 gram, Radix Et Rhizoma Rhei 1~30 gram, Cornu Saigae Tataricae 1~20 gram, Folium Mori 1~40 gram, Pericarpium Citri Reticulatae Viride 1~50 gram, Poria 1~50 gram, Talcum 1~40 gram, Massa Medicata Fermentata 1~40 gram, Fructus Crataegi 1~40 gram, Rhizoma Alismatis 1~40 gram, Semen Plantaginis 1~30 gram, Herba Lysimachiae 1~40 gram, Semen Coicis 1~30 gram.
2. according to the described Chinese medicine composition of claim 1, it is characterized in that: the weight portion of each crude drug is:
Herba Artemisiae Scopariae 30 grams, Rhizoma Coptidis 20 grams, Radix Puerariae 30 grams, Flos Lonicerae 30 grams, Flos Chrysanthemi 15 grams, Gypsum Fibrosum 30 grams, the Rhizoma Anemarrhenae 30 grams, Radix Bupleuri 30 grams, Fructus Gardeniae 20 grams, Radix Isatidis 30 grams, Folium Isatidis 20 grams, Herba Houttuyniae 20 grams, Herba Artemisiae Annuae 15 grams, Herba Lophatheri 30 grams, Radix Arnebiae (Radix Lithospermi) 20 grams, Radix Gentianae 30 grams, Radix Sophorae Flavescentis 20 grams, Cortex Fraxini 15 grams, Radix Et Rhizoma Rhei 15 grams, Cornu Saigae Tataricae 6 grams, Folium Mori 20 grams, Pericarpium Citri Reticulatae Viride 20 grams, Poria 30 grams, Talcum 20 grams, Massa Medicata Fermentata 30 grams, Fructus Crataegi 15 grams, Rhizoma Alismatis 20 grams, Semen Plantaginis 20 grams, Herba Lysimachiae 20 grams, Semen Coicis 20 grams.
3. according to the described Chinese medicine composition of claim 1, wherein crude drug also has:
Rhizoma Cyperi 1~50 gram, the Radix Aucklandiae 1~40 gram, Herba Pogostemonis 1~40 gram, Folium Perillae 1~40 gram, Rhizoma Atractylodis 1~30 gram, Cortex Magnoliae Officinalis 1~40 gram, Fructus Toosendan 1~40 gram, Lignum Dalbergiae Odoriferae 1~30 gram, Squama Manis 1~20 gram, Lignum Aquilariae Resinatum 1~20 gram, Fructus Amomi 1~20 gram, Radix Scutellariae 1~40 gram, Cortex Lycii 1~50 gram, Herba Taraxaci 1~40 gram, Herba Violae 1~40 gram, Radix Sophorae Tonkinensis 1~50 gram, Fructus Arctii 1~40 gram, Radix Scrophulariae 1~40 gram.
4. according to the described Chinese medicine composition of claim 3, wherein the weight portion of each component is:
Rhizoma Cyperi 30 grams, the Radix Aucklandiae 30 grams, Herba Pogostemonis 20 grams, Folium Perillae 20 grams, Rhizoma Atractylodis 20 grams, Cortex Magnoliae Officinalis 20 grams, Fructus Toosendan 30 grams, Lignum Dalbergiae Odoriferae 15 grams, Squama Manis 10 grams, Lignum Aquilariae Resinatum 5 grams, Fructus Amomi 15 grams, Radix Scutellariae 20 grams, Cortex Lycii 30 grams, Herba Taraxaci 30 grams, Herba Violae 25 grams, Radix Sophorae Tonkinensis 30 grams, Fructus Arctii 30 grams, Radix Scrophulariae 20 grams.
5. according to claim 1,2,3 or 4 described any Chinese medicine compositions, it is characterized in that: can be prepared into any oral formulations commonly used according to the method for Chinese medicinal of routine.
6. according to the described Chinese medicine composition of claim 5, it is characterized in that: described oral formulations is pill, capsule, tablet, powder, granule or oral liquid.
7. the application of the described any Chinese medicine composition of claim 1~6 in preparation treatment icterohepatitis disease medicine.
CN2009103092659A 2009-11-04 2009-11-04 Traditional Chinese medicine composition for treating icterohepatitis and preparation method thereof Expired - Fee Related CN101757509B (en)

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