CN101731630A - Health-care food with effects of neutralizing effect of alcoholic drinks and protecting liver - Google Patents
Health-care food with effects of neutralizing effect of alcoholic drinks and protecting liver Download PDFInfo
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Abstract
The invention discloses a health-care food with the effects of neutralizing the effect of alcoholic drinks and protecting the liver. The health-care food comprises the following components by weight percent: 1.0-100.0% of corn flour oligopeptide, 0.0-40.0% of taurine, 0.0-30.0% of alanine, 0.0-50.0% of cysteine, 0.0-30.0% of leucine, 0.0-30.0% of glutathione, 0.0-30.0% of hoveniae semoveniae semen extract, 0.0-30.0% of brown rice germ, 0.0-30.0% of radix puerariae extract and 0.0-95.0% of auxiliary materials. In the invention, various raw materials with definite effects are reasonably matched by a scientific prescription, the alcohol metabolism of a human body can be effectively promoted, and the toxicity of alcohol to the liver is lowered, thereby exerting the functions of neutralizing the effect of alcoholic drinks and protecting the liver.
Description
Technical field
The present invention relates to a kind of health food, more particularly, the present invention relates to a kind of health food that relieves the effect of alcohol, protects the liver function effect that has.
Background technology
China is the big country of drinks consumption, all communications of unavoidable wine such as commercial affairs dinner party, kith and kin's gathering, and the lighter's impariment of the liver evil stomach of drinking, and weight person can cause alcoholism, causes nervous exhaustion, phrenoblabia and organ damage, all health is caused acute or chronic damage.Therefore, the product with promoting digestion and protecting liver, anti-intoxication alcohol neutralizing effect also just becomes a kind of needs of socialization.Disintoxicating product in the market is of a great variety; have and occur with the bread and cheese form; also have and occur with the health food form; but the effect of bread and cheese is difficult to guarantee; and the function of health food declares it is that chemical damage is had auxiliary protection function, and product wherein is to be raw material with the plant extracts mostly.
The mixture of the corn peptide multiple little peptide that to be zein obtain through the enzyme degraded.Corn peptide has multiple biologically active, as anti-oxidant, anti-hypertension, enhancing immunity, antifatigue, protection liver etc.It should be noted that animal and human's body test discovery, corn peptide also has functional characteristic a---sobering-up functions important and don't that be same as other food oligopeptide.As seen antialcoholism function food must have good market prospects to utilize corn peptide to develop safely and effectively.
Summary of the invention
The object of the present invention is to provide a kind of health food that relieves the effect of alcohol, protects the liver function effect that has.The present invention is by scientific composition, and each function raw material is reasonably combined, can effectively promote the human body alcohol metabolism, reduce the toxicity of alcohol to liver, thereby the effect of liver is relieved the effect of alcohol, protected in performance.
Of the present invention have relieve the effect of alcohol, protect the health food that liver function is imitated, comprise following component by weight percentage:
Corn oligopeptide powder 1.0%～100.0%; Taurine 0.0%～40.0%;
Alanine 0.0%～30.0%; Cysteine 0.0%～50.0%;
Leucine 0.0%～30.0%; Glutathione 0.0%～30.0%;
Raisin tree seed extract 0.0%～30.0%; Brown rice germ 0.0%～30.0%;
Kudzu root extract 0.0%～30.0%; Auxiliary material 0.0%～95.0%.
In the present invention, described corn oligopeptide powder is made by following method: get an amount of zein powder raw material adding pure water and size mixing; Be heated to 70-95 ℃ and kept 20-40 minute subsequently, carry out centrifugation again; Get that isolated sediment repeats to size mixing, heating and centrifugally operated; Transfer in the enzymatic vessel after the emulsification of gained sediment, to 40-60 ℃, the pH value is adjusted to 8.0-9.0, adds bacillus licheniformis protease and papain again and carries out enzymolysis with the adjustment of enzymatic vessel; Carrying out the instantaneous enzyme that goes out of high temperature after enzymolysis finishes handles; The gained enzymolysis liquid carries out centrifugation, and clear liquid carries out low temperature and concentrates and use activated carbon decolorizing after filtering; Sterilize at last and spray drying treatment, promptly obtain described corn oligopeptide powder.
In the present invention, described corn oligopeptide powder can also be made by following method: get an amount of zein powder raw material adding deionized water and size mixing; With sodium hydroxide solution the pH value of slurries is adjusted to 9.0-11.0; Be heated to 90-105 ℃, soaked 1-3 hour; Be cooled to 45-65 ℃ subsequently, under the condition of pH9.0-11.0, add bacillus licheniformis protease and carry out enzymolysis; The gained enzymolysis liquid is continued to be cooled to 30-45 ℃, and its pH value is adjusted to 7.0-8.5, add Validase TSP Concentrate II and carry out enzymolysis with hydrochloric acid solution; After enzymolysis finishes, the gained enzymolysis liquid enzyme that goes out is handled; Enzymolysis liquid behind the enzyme that goes out is carried out centrifugation, and the gained clear liquid filters, and is separated into micromolecular peptide liquid and trapped fluid; Peptide liquid is concentrated, carry out instantaneous UHTS subsequently and handle; Carry out spray drying treatment at last, promptly obtain described corn oligopeptide powder.
The prepared corn oligopeptide of the present invention powder, its protein content 〉=60%, the above peptide molecular weight in peptide content 〉=55%, 60%≤1000 dalton (dalton).
In the present invention, described raisin tree seed extract is made by following method: get an amount of hoveniae semoveniae semen medicine materical crude slice, drop in the extractor, boiling is filtered; Collect filtrate, get supernatant and carry out vacuum decompression and concentrate; Get the medicinal extract that obtains after concentrating, add an amount of maltodextrin, heating stirs; Carry out spray drying treatment at last, promptly obtain described raisin tree seed extract.
In the present invention, described kudzu root extract is made by following method: get an amount of root of kudzu vine medicine materical crude slice, drop in the extractor, boiling is filtered; Collect filtrate, get supernatant and carry out vacuum decompression and concentrate; Get the medicinal extract that obtains after concentrating, add an amount of maltodextrin, heating stirs; Carry out spray drying treatment at last, promptly obtain described kudzu root extract.
In the present invention, described auxiliary material comprises following component by weight percentage:
Fruit powder 0.0%～30.0%; Flavoring essence 0.0%～10.0%;
Sweetener 0.0%～10.0%; Acid 0.0%～20.0%;
Adhesive 0.0%～20.0%; Filler 0.0%～80.0%;
Lubricant 0.0%～5.0%; Diluent 0.0%～95.0%;
Dressing material 0.0%～10.0%; Local flavor conditioning agent 0.0%～5.0%;
Suspending agent 0.0%～5.0%; Anticorrisive agent 0.0%～5.0%.
Wherein, Fruit powder is selected from sea-buckthorn powder, orange powder, lemon powder, cherry powder, apple powder, coconut palm powder etc.; Flavoring essence is selected from corn essence, grapefruit essence, orange essence, lemon extract, cherry essence, flavoring apple essence, cocoanut flavour etc.; It is sweet etc. that sweetener is selected from Sucralose, steviol glycoside, AK sugar, Aspartame, mogroside, knob; Acid is selected from citric acid, malic acid, lactic acid, tartaric acid, fumaric acid etc.; Adhesive is selected from HPMC, methylcellulose, PVP, starch slurry, dextrin, Icing Sugar, syrup, rubber cement, gelatin, microcrystalline cellulose or other celluloses and derivative thereof etc.; Filler is selected from fructose, sugar alcohol (comprising isomalt, antierythrite, D-sorbite, mannitol, maltitol etc.), sucrose, starch, dextrin, microcrystalline cellulose etc.; Lubricant is selected from talcum powder, dolomol, silica, stearic acid etc.; Diluent is selected from alcohol, glycerine, propane diols, polyoxyethylene sorbitan monoleate, water, edible oil (comprising soybean oil) etc.; The dressing material is selected from HPMC, talcum powder, polyvinyl alcohol, polyethylene glycol, Tween 80, PVP, hydroxyethylcellulose and colouring agent, covers photo etching etc.; The local flavor conditioning agent is selected from malt extract, lipid end, salt etc.; Suspending agent is selected from beeswax, sapn, tween, polyethylene glycol etc.; Anticorrisive agent is selected from parabens, sorbic acid salt and ditert-butylhydro quinone etc.
Health food of the present invention can be made into the oral formulations such as tablet, pulvis, granule, hard capsule, soft capsule and oral liquid of various tastes.
The present invention is according to the Human Physiology needs, the raw material of above-mentioned various exact efficacy is carried out scientific composition, thereby guarantee the effect of product.In the present invention, the oligomeric Toplink of corn is absorbed rapidly in vivo, and amino acid can be brought into play carry again, and the amino acid content level in the blood can be effectively kept in its collocation for a long time, helps the synthetic and metabolism of liver enzyme; Simultaneously, select for use the definite plant extracts of sober-up function to arrange in pairs or groups, and add antioxidant, can in time remove the free radical in the body, the liver function of relieving the effect of alcohol, protect of more effectively bringing into play product is imitated.The selected various raw materials of the present invention are all taken from edible natural materials, and are nontoxic, safe and reliable.
Take in the interior alcohol of body after gastrointestinal absorption, mainly metabolism in liver is acetaldehyde and acetate by alcohol dehydrogenase and acetaldehyde dehydrogenase metabolism, and finally the form with acetate participates in the human homergy.Alanine, leucine are the key amino acids relevant with alcohol metabolism, and alanine can promote the decomposition of alcohol in the blood, have the enhancing liver function, the effect of liver protecting; Leucine then can alleviate the symptom that alcohol causes chemical reaction imbalance in the human body, and helps to prevent alcoholism.In addition, take in the generation that alcohol can suppress glutamic acid, and glutamic acid can participate in the albumen and the glycometabolism of brain, accelerating oxidation, improve the nervous centralis activity, keeping arranged and promote the effect of function of brain cell, therefore replenish glutamic acid and can alleviate the neurological symptom that alcohol causes.
Corn oligopeptide of the present invention contains a high proportion of alanine and leucine, can improve alanine and leucic concentration in the blood after the absorption, produce the codehydrogenase of stable decomposition ethanol, thereby strengthen the activity of L-AD and acetaldehyde dehydrogenase, promote the decomposition and the metabolism of ethanol in the body, thereby reduce the concentration of ethanol in blood, reach the effect that reduces drunk degree and sober up.Animal experiment shows, successively irritates food corn oligopeptide powder and ethanol, compares with check sample, and the content of ethanol in the blood and oxidation product thereof (being acetaldehyde) all obviously reduces.Also obtain same result in the human trial, the ethanol content in the blood relatively significantly reduces, and the alanine in the blood plasma, leucine, proline content then significantly improve, and keeps high level and reach 2h.Simultaneously, contain a large amount of glutamic acid in the corn oligopeptide, can replenish glutamic acid after the absorption, thereby keep the energy supply and the nervous activity of brain cell, alleviate the neurological symptom that alcohol causes because of reduced by the alcohol inhibition.In addition, the corn oligopeptide also has significant antioxidant role, and the hepatic injury that number of chemical materials such as carbon tetrachloride thioacetamide, alcohol are caused all has protective effect.Animal experiment confirms that the oligomeric Toplink of corn significantly reduces the content of MDA in the alcoholic liver injury model mice hepatic tissue, total triglycerides, and increases the content of reduced glutathione.Pathological examination also shows that the corn oligopeptide can obviously alleviate hepatic cell fattydegeneration, obviously improves the liver tissue injury degree.The corn oligopeptide helps keeping the eubolism of liver to alcohol in the body to the protective effect of liver.Moreover corn oligopeptide powder of the present invention is a kind of low peptide material that is made through enzymolysis by corn protein powder, has characteristics such as easy digestion, easy absorption.
Taurine is a kind of beta-amino acids that is transformed by sulfur-containing amino acid, and the free interior various tissues of human body that are present in are the abundantest free amino acids of animal body intensive amount.Taurine is as the active ingredient of rare Chinese medicine " cow-bezoar "; have heat-clearing, analgesia, calmness, anticonvulsion, platelet aggregation-against, anti-arrhythmia cordis, hypotensive, hypoglycemic, increase immunity, mend courage, protecting liver and detoxication, adjusting antiotasis, correct multiple pharmacological effect such as vivo acid is unbalance.
Alanine is a kind of branched-chain amino acid of needed by human body, and additional alanine can satisfy the body metabolism needs, continues to keep the alanine concentration in the blood, guarantees human homergy's carrying out, and also can improve product special flavour simultaneously.
Leucine is one of 8 kinds of essential amino acids of human body, also be a kind of branched-chain amino acid, can the oxidation energy supply in special physiological period, can be used for replenishing the energy consumption that large amount of exercise causes, alleviate the fatigue reaction of the central nervous system that causes thus, reduce the protein decomposition that high-intensity exercise causes.
Cysteine is a sulfur-containing amino acid, plays different physiological roles in animal body, comprise ingest, grow, immune, anti-oxidant etc.Result of study shows that DL-cysteine may have the effect of blocking-up hepatic injury.The CCl4 hepatotoxicity has stimulated liver cell SOD increased activity again when bringing out the free radical generation, FCCP is a kind of oxidative phosphorylation uncoupler of brute force, it is synthetic to suppress cell mitochondrial ATP rapidly, accelerates ATP and exhausts, body cell is ATP and damaged for want of.APT, zmount of oxygen consumption and the lactic dehydrogenase effusion rates etc. that cysteine can make FCCP cause recover normal.Result of study shows that also cysteine has certain effect to treatment and prevention TNT poisoning.There is report in Japan, in amino acid is tested alcohol metabolism, irritates and compares with blank control group with the L-cysteine, and L-cysteine group mouse can be removed oxidation fast and be removed acetaldehyde, the acetaldehyde less residue in mouse blood, liver and the brain.
Glutathione be by glutamic acid, cysteine and glycine by the tripeptide compound that the peptide bond condensation forms, have anti-oxidant, detoxifcation, radiation protection, protection liver, antiallergy, the course of disease of improving some disease and symptom, skin maintenance skin care, strengthen eyesight, the anti-ageing effect of waiting for a long time.
Brown rice germ contains abundant GABA, has hypotensive, reducing blood lipid, adjusting arrhythmia cordis, regulates hormone secretion, strengthens the effect of renal function, activation liver function and prevention of obesity, and can bring into play multiple physiological hygiene function.
Kudzu root extract is to be extracted and got by the dry root that the pulse family Pueraria lobota belongs to class plant elegant jessamine or sweet Pueraria lobota, Pachyrhizua angulatus, the sweet cold of its nature and flavor, have " sweet light, nontoxic, heat extraction, quench the thirst, defaecation, relieve the effect of alcohol, nourishing the stomach " effect.
Raisin tree seed extract is to be extracted and got by the fruits and seeds that Rhamnaceae Hovenia hoveniae semoveniae semen has a meat carpopodium, has effects such as " relieving alcoholism, Shujin networks ".Modern pharmacological research shows that its main active is the dammarane type triterpenoid saponin, has anti peroxidation of lipid, protects the liver, relieving alcoholism and suppress the pharmacological action of aspects such as nervous centralis.
Description of drawings
Fig. 1 is the tablet producing technology flow chart of swallowing of health food of the present invention;
Fig. 2 is the chewable tablet preparation technology flow chart of health food of the present invention;
Fig. 3 is the pulvis preparation technology flow chart of health food of the present invention;
Fig. 4 is the granule preparation technology flow chart of health food of the present invention;
Fig. 5 is the hard capsule preparation technology flow chart of health food of the present invention;
Fig. 6 is the soft capsule preparation technology flow chart of health food of the present invention;
Fig. 7 is the oral liquid preparation technology flow chart of health food of the present invention.
The specific embodiment
Embodiment one: the preparation of corn oligopeptide powder
Get the pure water of 40-65 ℃ of an amount of zein powder raw material adding and size mixing, wherein the mass ratio of solid content and pure water is 1: 10; Be heated to 70-95 ℃ and kept 20-40 minute subsequently, the rotating speed with 3000rpm carries out centrifugation again; Get that isolated sediment repeats to size mixing, heating and centrifugally operated; Transfer in the enzymatic vessel after the emulsification of gained sediment, with the adjustment of enzymatic vessel to 40-60 ℃, the pH value is adjusted to 8.0-9.0, added again bacillus licheniformis protease and papain enzymolysis 2-4 hour, wherein the addition of bacillus licheniformis protease is the 0.01%-0.10% of substrate content, the addition of papain is the 0.10%-0.25% of substrate content, does not stop during the enzymolysis to stir; Enzymolysis finishes the back with the enzyme processing of going out of the instantaneous mode of high temperature; The gained enzymolysis liquid carries out twice centrifugation, removes residue, and clear liquid is behind the secondary membrane filtration, and low temperature is concentrated into the 20-40 Baume, and with activated carbon decolorizing 40 minutes; Sterilize at last and spray drying treatment, promptly obtain described corn oligopeptide powder.
Embodiment two: the preparation of corn oligopeptide powder
Get an amount of zein powder raw material adding deionized water and size mixing, concentration is 5%-10%; Survey the pH value of slurries, and its pH value is adjusted to 9.0-11.0 with the sodium hydroxide solution of 20%-40%; Be heated to 90-105 ℃, soaked 1-3 hour; Be cooled to 45-65 ℃ subsequently, under the condition of pH9.0-11.0, added the bacillus licheniformis protease hydrolyzed 3-6 hour; The gained enzymolysis liquid is continued to be cooled to 30-45 ℃, and its pH value is adjusted to 7.0-8.5, added the Validase TSP Concentrate II enzymolysis 2-5 hour with the hydrochloric acid solution of 20%-40%; After enzymolysis finishes, adopt plate type heat exchanger, under 115-125 ℃, the gained enzymolysis liquid enzyme that goes out is handled; Enzymolysis liquid behind the enzyme that goes out is carried out centrifugation, and the gained clear liquid filters by membrane-filtering unit, is separated into micromolecular peptide liquid and trapped fluid; Use the triple effect thickener ,-0.07Mpa, under 70 ℃ the vacuum condition, it is 30-35% that peptide liquid is concentrated into solid content; Use instantaneous superhigh temperature disinfecting machine subsequently, under 125-135 ℃, carry out sterilization treatment; Be 170 ℃ in inlet temperature at last, outlet temperature is to carry out spray drying treatment under 80 ℃ the condition, promptly obtains described corn oligopeptide powder.
Embodiment three: the preparation of raisin tree seed extract
Get an amount of hoveniae semoveniae semen medicine materical crude slice, handle making it fully moistening, standby by water spray; Medicine materical crude slice is dropped in the extractor, boiling three times, primary amount of water is 15 times of medicinal material amount, decoct after 2 hours and filter, secondary amount of water is 10 times of medicinal material amount, decocts after 1.5 hours and filters, amount of water for the third time is 10 times of medicinal material amount, decocts after 1 hour to filter; The filtrate that merges three gained is extracted supernatant and is entered vacuum concentrator, at 60～80 ℃ ,-0.01～-condition of 0.06Mpa under vacuum decompression to be concentrated into relative density be 1.05～1.08 (under 80 ℃), 350 orders filter; Get the medicinal extract that obtains after concentrating, add an amount of maltodextrin, heating stirs; Be 175-185 ℃ at EAT at last, leaving air temp is to carry out spray drying treatment under 85-95 ℃ the condition, collects the raisin tree seed extract powder that makes.
Embodiment four: the preparation of kudzu root extract
Get an amount of root of kudzu vine medicine materical crude slice, handle making it fully moistening, standby by water spray; Medicine materical crude slice is dropped in the extractor, boiling twice, primary amount of water is 15 times of medicinal material amount, decocts after 2 hours to filter, secondary amount of water is 10 times of medicinal material amount, decocts after 1.5 hours to filter; The filtrate that merges gained is extracted supernatant and is entered vacuum concentrator, at 60～80 ℃ ,-0.01～-condition of 0.06Mpa under vacuum decompression to be concentrated into relative density be 1.05～1.08 (under 80 ℃), 350 orders filter; Get the medicinal extract that obtains after concentrating, add an amount of maltodextrin, heating stirs; Be 175-185 ℃ at EAT at last, leaving air temp is to carry out spray drying treatment under 85-95 ℃ the condition, collects the kudzu root extract powder that makes.
Embodiment five: the preparation of the tablet of swallowing of described health food
Corn oligopeptide powder 40.0%; Taurine 5.0%; Alanine 5.0%;
Cysteine 15.0%; Brown rice germ 5.0%; PVP 3.0%;
HPMC 5.0%; Dolomol 0.4%; Silica 0.2%;
Microcrystalline cellulose 20.4%; Dressing material 1.0%.
Earlier corn oligopeptide powder, taurine, alanine, cysteine, brown rice germ, PVP, HPMC, microcrystalline cellulose, sucrose are pulverized, sieved; By formula ratio take by weighing pulverizing successively, material after sieving; Load weighted material is dropped into mixer, mix; Add an amount of alcohol, granulate by granulator; The particle that makes is carried out drying with drying equipment, carry out whole grain by pelletizing machine subsequently; Adding dolomol, silica carry out always mixing, and the material that always is mixed after sparing is carried out compressing tablet by tablet press machine, and plain sheet is temporary, and is standby; The dressing material is added in the suitable quantity of water, stir, be mixed with the coating solution that concentration is 5.0%-15.0%, the plain sheet that presses is carried out Cotton seeds by the dressing machine; Last packing promptly makes the tablet of swallowing of health food of the present invention.
Embodiment six: the preparation of the chewable tablet of described health food
Corn oligopeptide powder 10.0%; Taurine 5.0%; Alanine 5.0%;
Brown rice germ 5.0%; Glutathione 0.5%; Kudzu root extract 5.0%;
Raisin Tree Seed extract 5.0%; Steviol glycoside 0.2%; Citric acid 2.0%;
Isomalt 50.7%; Sea-buckthorn powder 10.0%; Corn essence 1.0%;
Dolomol 0.4%; Silica 0.2%.
Earlier corn oligopeptide powder, taurine, alanine, brown rice germ, glutathione, kudzu root extract, Raisin Tree Seed extract, sea-buckthorn powder, isomalt, steviol glycoside, citric acid are pulverized, sieved; By formula ratio take by weighing pulverizing successively, material after sieving; Load weighted material is dropped into mixer, mix; Add an amount of alcohol, granulate by granulator; The particle that makes is carried out drying with drying equipment, carry out whole grain by pelletizing machine subsequently; Adding dolomol, silica, corn essence carry out always mixing, and the material that always is mixed after sparing is carried out compressing tablet by tablet press machine; Last packing promptly makes the chewable tablet of health food of the present invention.
Execute example seven: the preparation of the pulvis of described health food
Corn oligopeptide powder 15.0%; Taurine 5.0%; Alanine 5.0%;
Leucine 5.0%; Glutathione 0.5%; Kudzu root extract 8.0%;
Raisin Tree Seed extract 10.0%; Malt extract 1.0%; Sucralose 0.2%;
Sea-buckthorn powder 5.0%; Citric acid 1.0%; Grapefruit essence 1.5%;
Antierythrite 42.8%.
Earlier above-mentioned each material is pulverized, sieved; By formula ratio take by weighing pulverizing successively, material after sieving; Load weighted material is dropped into mixer, mix; After the packing, promptly make the pulvis of health food of the present invention.
Embodiment eight: the preparation of the granule of described health food
Corn oligopeptide powder 20.0%; Taurine 5.0%; Alanine 5.0%;
Cysteine 15.0%; Kudzu root extract 5.0%; Raisin Tree Seed extract 5.0%;
Aspartame 0.2%; Malic acid 2.0%; Corn essence 1.0%;
Isomalt 31.8%; Sucrose 10.0%.
Earlier above-mentioned each material is pulverized, sieved; By formula ratio take by weighing pulverizing successively, material after sieving; Load weighted material is dropped into mixer, mix; Add an amount of alcohol, granulate by granulator; The particle that makes is carried out drying with drying equipment, carry out whole grain by pelletizing machine subsequently; Last packing promptly makes the granule of health food of the present invention.
Embodiment nine: the preparation of the hard capsule of described health food
Corn oligopeptide powder 94.0%; Taurine 2.0%; Glutathione 1.0%;
Kudzu root extract 2.0%; Silica 1 .0%.
Earlier above-mentioned each material is pulverized, sieved; By formula ratio take by weighing pulverizing successively, material after sieving; Load weighted material is dropped into mixer, mix; By capsule filler capsule is filled then; Last packing promptly makes the hard capsule of health food of the present invention.
Embodiment ten: the preparation of the soft capsule of described health food
The prescription of soft capsule peel is as follows:
Gelatin 36.0%; Glycerine 18.0%;
Methyl p-hydroxybenzoate 0.06%; Water 45.94%.
After taking by weighing above-mentioned rubber raw material by formula ratio, change glue in the inputization glue jar; The rubber solution of gained is transferred in the bucket of band attemperator after by colloid mill, is connected on the soft capsule pellet press, be used to prepare soft capsule peel.
The prescription of health food of the present invention is as follows:
Corn oligopeptide powder 10.0%; Taurine 3.0%; Kudzu root extract 5.0%;
Raisin Tree Seed extract 6.0%; Soybean oil 73.8%; Beeswax 2.0%;
Ditert-butylhydro quinone 0.2%.
Earlier corn oligopeptide powder, taurine, kudzu root extract, Raisin Tree Seed extract are pulverized, sieved; Material after sieving by the formula ratio weighing, standby; Take by weighing soybean oil, beeswax and ditert-butylhydro quinone by formula ratio, be heated dissolving, drop in the above-mentioned standby material, stir, make its emulsification; Obtain uniform and stable emulsion by colloid mill then.Above-mentioned emulsion is put into reservoir, be injected in the soft capsule peel, suppress by the soft capsule pellet press; The soft capsule that presses is cleaned, and be cured by drying equipment; Last packing promptly makes the soft capsule of health food of the present invention.
Embodiment 11: the preparation of the oral liquid of described health food
Corn oligopeptide powder 30.0%; Taurine 5.0%; Alanine 8.0%;
Leucine 8.0%; Kudzu root extract 8.0%; Raisin Tree Seed extract 10.0%;
Sucralose 0.2%; Orange powder 5.0%; Citric acid 1.5%;
Orange essence 1.5%; Sucrose 22.8%.
Take by weighing above-mentioned each material by formula ratio, drop in the water, fully dissolving; Then gained solution is transferred in the oral liquid bottle placer, injects in the container; Sterilize, promptly make the oral liquid of health food of the present invention.
Claims (10)
1. one kind has the health food that relieves the effect of alcohol, protects the liver function effect, comprises following component by weight percentage:
Corn oligopeptide powder 1.0%～100.0%; Taurine 0.0%～40.0%;
Alanine 0.0%～30.0%; Cysteine 0.0%～50.0%;
Leucine 0.0%～30.0%; Glutathione 0.0%～30.0%;
Raisin tree seed extract 0.0%～30.0%; Brown rice germ 0.0%～30.0%;
Kudzu root extract 0.0%～30.0%; Auxiliary material 0.0%～95.0%.
2. health food according to claim 1 is characterized in that, described corn oligopeptide powder is made by following method: get an amount of zein powder raw material adding pure water and size mixing; Be heated to 70-95 ℃ and kept 20-40 minute subsequently, carry out centrifugation again; Get that isolated sediment repeats to size mixing, heating and centrifugally operated; Transfer in the enzymatic vessel after the emulsification of gained sediment, to 40-60 ℃, the pH value is adjusted to 8.0-9.0, adds bacillus licheniformis protease and papain again and carries out enzymolysis with the adjustment of enzymatic vessel; Carrying out the instantaneous enzyme that goes out of high temperature after enzymolysis finishes handles; The gained enzymolysis liquid carries out centrifugation, and clear liquid carries out low temperature and concentrates and use activated carbon decolorizing after filtering; Sterilize at last and spray drying treatment, promptly obtain described corn oligopeptide powder.
3. health food according to claim 1 is characterized in that, described corn oligopeptide powder is made by following method: get an amount of zein powder raw material adding deionized water and size mixing; With sodium hydroxide solution the pH value of slurries is adjusted to 9.0-11.0; Be heated to 90-105 ℃, soaked 1-3 hour; Be cooled to 45-65 ℃ subsequently, under the condition of pH9.0-11.0, add bacillus licheniformis protease and carry out enzymolysis; The gained enzymolysis liquid is continued to be cooled to 30-45 ℃, and its pH value is adjusted to 7.0-8.5, add Validase TSP Concentrate II and carry out enzymolysis with hydrochloric acid solution; After enzymolysis finishes, the gained enzymolysis liquid enzyme that goes out is handled; Enzymolysis liquid behind the enzyme that goes out is carried out centrifugation, and the gained clear liquid filters, and is separated into micromolecular peptide liquid and trapped fluid; Peptide liquid is concentrated, carry out instantaneous UHTS subsequently and handle; Carry out spray drying treatment at last, promptly obtain described corn oligopeptide powder.
4. health food according to claim 1 is characterized in that: in the described corn oligopeptide powder, and protein content 〉=60%, the above peptide molecular weight in peptide content 〉=55%, 60%≤1000 dalton.
5. health food according to claim 1 is characterized in that, described raisin tree seed extract is made by following method: get an amount of hoveniae semoveniae semen medicine materical crude slice, drop in the extractor, boiling is filtered; Collect filtrate, get supernatant and carry out vacuum decompression and concentrate; Get the medicinal extract that obtains after concentrating, add an amount of maltodextrin, heating stirs; Carry out spray drying treatment at last, promptly obtain described raisin tree seed extract.
6. health food according to claim 1 is characterized in that, described kudzu root extract is made by following method: get an amount of root of kudzu vine medicine materical crude slice, drop in the extractor, boiling is filtered; Collect filtrate, get supernatant and carry out vacuum decompression and concentrate; Get the medicinal extract that obtains after concentrating, add an amount of maltodextrin, heating stirs; Carry out spray drying treatment at last, promptly obtain described kudzu root extract.
7. health food according to claim 1 is characterized in that, described auxiliary material comprises following component by weight percentage:
Fruit powder 0.0%～30.0%; Flavoring essence 0.0%～10.0%;
Sweetener 0.0%～10.0%; Acid 0.0%～20.0%;
Adhesive 0.0%～20.0%; Filler 0.0%～80.0%;
Lubricant 0.0%～5.0%; Diluent 0.0%～95.0%;
Dressing material 0.0%～10.0%; Local flavor conditioning agent 0.0%～5.0%;
Suspending agent 0.0%～5.0%; Anticorrisive agent 0.0%～5.0%.
8. health food according to claim 7 is characterized in that: described Fruit powder is selected from one or more the mixing in sea-buckthorn powder, orange powder, lemon powder, cherry powder, apple powder and the coconut palm powder; Described flavoring essence is selected from one or more the mixing in corn essence, grapefruit essence, orange essence, lemon extract, cherry essence, flavoring apple essence and the cocoanut flavour; Described sweetener is selected from one or more the mixing in sweet of Sucralose, steviol glycoside, AK sugar, Aspartame, mogroside and knob; Described acid is selected from one or more the mixing in citric acid, malic acid, lactic acid, tartaric acid and the fumaric acid; Described adhesive is selected from one or more the mixing in HPMC, methylcellulose, PVP, starch slurry, dextrin, Icing Sugar, syrup, rubber cement, gelatin and the microcrystalline cellulose; Described filler is selected from one or more the mixing in fructose, sugar alcohol, sucrose, starch, dextrin and the microcrystalline cellulose; Described lubricant is selected from one or more the mixing in talcum powder, dolomol, silica and the stearic acid; Described diluent is selected from one or more the mixing in alcohol, glycerine, propane diols, polyoxyethylene sorbitan monoleate, water and the edible oil; Described dressing material is selected from HPMC, talcum powder, polyvinyl alcohol, polyethylene glycol, Tween 80, PVP, hydroxyethylcellulose and colouring agent, cover one or more the mixing in the photo etching; Described local flavor conditioning agent is selected from one or more the mixing in malt extract, lipid end and the salt; Described suspending agent is selected from one or more the mixing in beeswax, sapn, tween and the polyethylene glycol; Described anticorrisive agent is selected from one or more the mixing in parabens, sorbic acid salt and the ditert-butylhydro quinone.
9. health food according to claim 1 is characterized in that: described product is prepared to oral formulations.
10. health food according to claim 9 is characterized in that: described oral formulations comprises pulvis, tablet, granule, hard capsule, soft capsule and oral liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010100239A CN101731630B (en) | 2010-01-22 | 2010-01-22 | Health-care food with effects of neutralizing effect of alcoholic drinks and protecting liver |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010100239A CN101731630B (en) | 2010-01-22 | 2010-01-22 | Health-care food with effects of neutralizing effect of alcoholic drinks and protecting liver |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101731630A true CN101731630A (en) | 2010-06-16 |
| CN101731630B CN101731630B (en) | 2012-10-10 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201010100239A Active CN101731630B (en) | 2010-01-22 | 2010-01-22 | Health-care food with effects of neutralizing effect of alcoholic drinks and protecting liver |
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Inventor after: Li Chenyue Inventor after: Ouyang Daofu Inventor after: Yu Qin Inventor after: Huang Chaoxia Inventor after: Wu Xiaochun Inventor after: Zhang Lixin Inventor after: Hu Ruilian Inventor after: Ding Liugang Inventor before: Hu Ruilian Inventor before: Li Chenyue Inventor before: Ouyang Daofu Inventor before: Yu Qin Inventor before: Huang Chaoxia Inventor before: Wu Xiaochun Inventor before: Ding Liugang |
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Free format text: CORRECT: INVENTOR; FROM: HU RUILIAN LI CHENYUE OUYANG DAOFU YU QIN HUANG ZHAOXIA WU XIAOCHUN DING LIUGANG TO: LI CHENYUE OUYANG DAOFU YU QIN HUANG ZHAOXIA WU XIAOCHUN ZHANG LIXIN HU RUILIAN DING LIUGANG |
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Effective date of registration: 20170123 Address after: 528402 Dongming Road, Guangdong city of Zhongshan province (Shiqi District Private Science and Technology Park) Patentee after: Perfect (China) Co., Ltd. Patentee after: Perfect (Guangdong) Commodity Co., Ltd. Address before: 528402 Dongming Road, Guangdong city of Zhongshan province (Shiqi District Private Science and Technology Park) Patentee before: Perfect (China) Co., Ltd. |