CN101730541B - 作为传染性病原体或毒素相关疾病的疫苗佐剂的细胞外基质材料 - Google Patents
作为传染性病原体或毒素相关疾病的疫苗佐剂的细胞外基质材料 Download PDFInfo
- Publication number
- CN101730541B CN101730541B CN200780052437.8A CN200780052437A CN101730541B CN 101730541 B CN101730541 B CN 101730541B CN 200780052437 A CN200780052437 A CN 200780052437A CN 101730541 B CN101730541 B CN 101730541B
- Authority
- CN
- China
- Prior art keywords
- infectious agent
- vaccine
- concerned
- adjuvant
- vaccine adjuvant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55588—Adjuvants of undefined constitution
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/699,448 | 2007-01-30 | ||
| US11/699,448 US9308252B2 (en) | 2005-10-27 | 2007-01-30 | Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins |
| PCT/US2007/069727 WO2008094276A1 (en) | 2007-01-30 | 2007-05-25 | Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101730541A CN101730541A (zh) | 2010-06-09 |
| CN101730541B true CN101730541B (zh) | 2014-03-05 |
Family
ID=39359947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200780052437.8A Expired - Fee Related CN101730541B (zh) | 2007-01-30 | 2007-05-25 | 作为传染性病原体或毒素相关疾病的疫苗佐剂的细胞外基质材料 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US9308252B2 (https=) |
| EP (1) | EP2114444B1 (https=) |
| JP (1) | JP2010516763A (https=) |
| CN (1) | CN101730541B (https=) |
| AU (1) | AU2007345673A1 (https=) |
| WO (2) | WO2008094276A1 (https=) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8257715B1 (en) | 2004-08-26 | 2012-09-04 | University Of Notre Dame | Tissue vaccines and uses thereof |
| US8802113B2 (en) * | 2005-10-27 | 2014-08-12 | University Of Notre Dame | Extracellular matrix cancer vaccine adjuvant |
| US8778360B2 (en) * | 2005-10-27 | 2014-07-15 | University Of Notre Dame | Extracellular matrix cancer vaccine adjuvant |
| US9308252B2 (en) | 2005-10-27 | 2016-04-12 | Cook Biotech, Inc. | Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins |
| US8097419B2 (en) | 2006-09-12 | 2012-01-17 | Longhorn Vaccines & Diagnostics Llc | Compositions and method for rapid, real-time detection of influenza A virus (H1N1) swine 2009 |
| US8080645B2 (en) | 2007-10-01 | 2011-12-20 | Longhorn Vaccines & Diagnostics Llc | Biological specimen collection/transport compositions and methods |
| US8652782B2 (en) | 2006-09-12 | 2014-02-18 | Longhorn Vaccines & Diagnostics, Llc | Compositions and methods for detecting, identifying and quantitating mycobacterial-specific nucleic acids |
| US9481912B2 (en) | 2006-09-12 | 2016-11-01 | Longhorn Vaccines And Diagnostics, Llc | Compositions and methods for detecting and identifying nucleic acid sequences in biological samples |
| US9683256B2 (en) | 2007-10-01 | 2017-06-20 | Longhorn Vaccines And Diagnostics, Llc | Biological specimen collection and transport system |
| US11041215B2 (en) | 2007-08-24 | 2021-06-22 | Longhorn Vaccines And Diagnostics, Llc | PCR ready compositions and methods for detecting and identifying nucleic acid sequences |
| US10004799B2 (en) | 2007-08-27 | 2018-06-26 | Longhorn Vaccines And Diagnostics, Llc | Composite antigenic sequences and vaccines |
| AU2008293504B2 (en) | 2007-08-27 | 2012-04-12 | Longhorn Vaccines & Diagnostics, Llc | Immunogenic compositions and methods |
| CA2861667C (en) | 2007-10-01 | 2017-06-13 | Longhorn Vaccines And Diagnostics, Llc | Biological specimen collection and transport system and methods of use |
| US11041216B2 (en) | 2007-10-01 | 2021-06-22 | Longhorn Vaccines And Diagnostics, Llc | Compositions and methods for detecting and quantifying nucleic acid sequences in blood samples |
| US9283266B2 (en) * | 2008-02-28 | 2016-03-15 | University Of Notre Dame | Metastasis inhibition preparations and methods |
| RU2572826C2 (ru) | 2008-12-02 | 2016-01-20 | Чиралджен, Лтд. | Способ синтеза модифицированных по атому фосфора нуклеиновых кислот |
| WO2010078478A1 (en) | 2008-12-31 | 2010-07-08 | Cook Biotech Incorporated | Tissue adjuvants and medical products including the same |
| CA2767253A1 (en) | 2009-07-06 | 2011-01-13 | Ontorii, Inc. | Novel nucleic acid prodrugs and methods of use thereof |
| US8846059B2 (en) | 2009-12-08 | 2014-09-30 | University Of Notre Dame | Extracellular matrix adjuvant and methods for prevention and/or inhibition of ovarian tumors and ovarian cancer |
| US20110150934A1 (en) * | 2009-12-18 | 2011-06-23 | University Of Notre Dame | Ovarian Tumor Tissue Cell Preparations/Vaccines for the Treatment/Inhibition of Ovarian Tumors and Ovarian Cancer |
| JP5868324B2 (ja) | 2010-09-24 | 2016-02-24 | 株式会社Wave Life Sciences Japan | 不斉補助基 |
| AU2012284265B2 (en) | 2011-07-19 | 2017-08-17 | Wave Life Sciences Ltd. | Methods for the synthesis of functionalized nucleic acids |
| WO2013112916A1 (en) | 2012-01-26 | 2013-08-01 | Longhorn Vaccines And Diagnostics, Llc | Composite antigenic sequences and vaccines |
| JP6453212B2 (ja) | 2012-07-13 | 2019-01-16 | ウェイブ ライフ サイエンシズ リミテッドWave Life Sciences Ltd. | キラル制御 |
| SG11201500239VA (en) | 2012-07-13 | 2015-03-30 | Wave Life Sciences Japan | Asymmetric auxiliary group |
| CN104684923B (zh) * | 2012-07-13 | 2018-09-28 | 株式会社新日本科学 | 手性核酸佐剂 |
| CN103110943B (zh) * | 2013-03-11 | 2014-11-26 | 浙江普康生物技术股份有限公司 | 一种可替代氢氧化铝的新型疫苗佐剂 |
| WO2015108048A1 (ja) | 2014-01-15 | 2015-07-23 | 株式会社新日本科学 | 抗腫瘍作用を有するキラル核酸アジュバンド及び抗腫瘍剤 |
| WO2015108047A1 (ja) | 2014-01-15 | 2015-07-23 | 株式会社新日本科学 | 免疫誘導活性を有するキラル核酸アジュバンド及び免疫誘導活性剤 |
| JPWO2015108046A1 (ja) | 2014-01-15 | 2017-03-23 | 株式会社新日本科学 | 抗アレルギー作用を有するキラル核酸アジュバンド及び抗アレルギー剤 |
| ES2917473T3 (es) | 2014-01-16 | 2022-07-08 | Wave Life Sciences Ltd | Diseño quiral |
| WO2016183292A1 (en) | 2015-05-14 | 2016-11-17 | Longhorn Vaccines And Diagnostics, Llc | Rapid methods for the extraction of nucleic acids from biological samples |
| CN106860861B (zh) * | 2017-03-03 | 2020-11-03 | 北京博辉瑞进生物科技有限公司 | 一种免疫增强组合物、制备方法及其应用 |
| US12485166B2 (en) | 2020-02-06 | 2025-12-02 | Longhorn Vaccines And Diagnostics, Llc | Vaccines for the treatment and prevention of zoonotic infections |
| EP4138781A1 (en) * | 2020-04-22 | 2023-03-01 | Fettech, Llc | Compositions comprising extracellular material with antiviral activity and uses thereof |
| KR20230091978A (ko) | 2020-10-20 | 2023-06-23 | 롱혼 백신즈 앤드 다이어그나스틱스, 엘엘씨 | 면역원성 항원 |
| JP2022151753A (ja) * | 2021-03-25 | 2022-10-07 | 国立大学法人 長崎大学 | 慢性感染症に対する免疫増強用組成物および慢性感染症治療用医薬 |
| US20250375512A1 (en) * | 2022-06-24 | 2025-12-11 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Use of matrix bound vesicles (mbv) as vaccine adjuvants |
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| US8802113B2 (en) | 2005-10-27 | 2014-08-12 | University Of Notre Dame | Extracellular matrix cancer vaccine adjuvant |
| US8778360B2 (en) | 2005-10-27 | 2014-07-15 | University Of Notre Dame | Extracellular matrix cancer vaccine adjuvant |
| US9308252B2 (en) | 2005-10-27 | 2016-04-12 | Cook Biotech, Inc. | Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins |
| US7545569B2 (en) * | 2006-01-13 | 2009-06-09 | Avery Dennison Corporation | Optical apparatus with flipped compound prism structures |
| CA2627364A1 (en) | 2007-01-30 | 2008-07-30 | University Of Notre Dame Du Lac | Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins |
| US9283266B2 (en) | 2008-02-28 | 2016-03-15 | University Of Notre Dame | Metastasis inhibition preparations and methods |
| US8846059B2 (en) | 2009-12-08 | 2014-09-30 | University Of Notre Dame | Extracellular matrix adjuvant and methods for prevention and/or inhibition of ovarian tumors and ovarian cancer |
| US20110150934A1 (en) | 2009-12-18 | 2011-06-23 | University Of Notre Dame | Ovarian Tumor Tissue Cell Preparations/Vaccines for the Treatment/Inhibition of Ovarian Tumors and Ovarian Cancer |
-
2007
- 2007-01-30 US US11/699,448 patent/US9308252B2/en active Active
- 2007-05-25 EP EP07797770.0A patent/EP2114444B1/en active Active
- 2007-05-25 JP JP2009547231A patent/JP2010516763A/ja active Pending
- 2007-05-25 AU AU2007345673A patent/AU2007345673A1/en not_active Abandoned
- 2007-05-25 CN CN200780052437.8A patent/CN101730541B/zh not_active Expired - Fee Related
- 2007-05-25 WO PCT/US2007/069727 patent/WO2008094276A1/en not_active Ceased
-
2008
- 2008-01-24 WO PCT/US2008/051877 patent/WO2008112344A2/en not_active Ceased
-
2009
- 2009-10-13 US US12/578,359 patent/US20100136050A1/en not_active Abandoned
-
2010
- 2010-08-26 US US12/868,908 patent/US9220770B2/en active Active
Non-Patent Citations (2)
| Title |
|---|
| Megumu Higaki et al.Collagen minipellet as a controlled release delivery system for tetanus and diphtheria toxoid.《Vaccine》.2001,第19卷第3091-3096页. * |
| 苏琰等.小肠粘膜下层修复组织缺损的应用研究.《国外医学·骨科学分册》.2004,第25卷(第1期),第43-45页. * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2114444A1 (en) | 2009-11-11 |
| US20080107665A1 (en) | 2008-05-08 |
| WO2008112344A2 (en) | 2008-09-18 |
| CN101730541A (zh) | 2010-06-09 |
| US9220770B2 (en) | 2015-12-29 |
| US9308252B2 (en) | 2016-04-12 |
| AU2007345673A1 (en) | 2008-08-07 |
| EP2114444A4 (en) | 2010-09-29 |
| US20100136050A1 (en) | 2010-06-03 |
| WO2008112344A3 (en) | 2009-12-30 |
| EP2114444B1 (en) | 2014-10-22 |
| US20110076305A1 (en) | 2011-03-31 |
| WO2008094276A1 (en) | 2008-08-07 |
| JP2010516763A (ja) | 2010-05-20 |
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