CN101730530B - 他喷他多的滴定 - Google Patents

他喷他多的滴定 Download PDF

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Publication number
CN101730530B
CN101730530B CN200880021172XA CN200880021172A CN101730530B CN 101730530 B CN101730530 B CN 101730530B CN 200880021172X A CN200880021172X A CN 200880021172XA CN 200880021172 A CN200880021172 A CN 200880021172A CN 101730530 B CN101730530 B CN 101730530B
Authority
CN
China
Prior art keywords
dose
dosage
dosing
administration
tapentadol hydrochloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN200880021172XA
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English (en)
Chinese (zh)
Other versions
CN101730530A (zh
Inventor
C·兰格
F·罗姆鲍特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruenenthal GmbH
Original Assignee
Gruenenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38123877&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN101730530(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gruenenthal GmbH filed Critical Gruenenthal GmbH
Publication of CN101730530A publication Critical patent/CN101730530A/zh
Application granted granted Critical
Publication of CN101730530B publication Critical patent/CN101730530B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Adhesive Tapes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN200880021172XA 2007-04-23 2008-04-21 他喷他多的滴定 Expired - Fee Related CN101730530B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP07008218A EP1985292A1 (en) 2007-04-23 2007-04-23 Titration of tapentadol
EP070082185 2007-04-23
EP07008218.5 2007-04-23
PCT/EP2008/003178 WO2008128740A1 (en) 2007-04-23 2008-04-21 Titration of tapentadol

Publications (2)

Publication Number Publication Date
CN101730530A CN101730530A (zh) 2010-06-09
CN101730530B true CN101730530B (zh) 2013-10-23

Family

ID=38123877

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880021172XA Expired - Fee Related CN101730530B (zh) 2007-04-23 2008-04-21 他喷他多的滴定

Country Status (21)

Country Link
US (4) US20090012180A1 (enExample)
EP (5) EP1985292A1 (enExample)
JP (4) JP5933176B2 (enExample)
KR (3) KR20150027840A (enExample)
CN (1) CN101730530B (enExample)
AT (1) ATE534378T1 (enExample)
AU (1) AU2008241013B2 (enExample)
CA (1) CA2683786C (enExample)
CY (1) CY1112320T1 (enExample)
DK (1) DK2148670T3 (enExample)
ES (1) ES2378255T3 (enExample)
HR (1) HRP20120147T1 (enExample)
IL (1) IL201479A (enExample)
MX (1) MX2009011444A (enExample)
NZ (1) NZ580415A (enExample)
PL (1) PL2148670T3 (enExample)
PT (1) PT2148670E (enExample)
RU (1) RU2472497C2 (enExample)
SI (1) SI2148670T1 (enExample)
WO (1) WO2008128740A1 (enExample)
ZA (1) ZA200907355B (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1985292A1 (en) * 2007-04-23 2008-10-29 Grünenthal GmbH Titration of tapentadol
WO2010096045A1 (en) * 2008-10-30 2010-08-26 Nectid, Inc. Novel and potent tapentadol dosage forms
US8870876B2 (en) * 2009-02-13 2014-10-28 Tarsus Medical Inc. Methods and devices for treating hallux valgus
US8277459B2 (en) 2009-09-25 2012-10-02 Tarsus Medical Inc. Methods and devices for treating a structural bone and joint deformity
US8652141B2 (en) 2010-01-21 2014-02-18 Tarsus Medical Inc. Methods and devices for treating hallux valgus
US20130116333A1 (en) * 2010-05-05 2013-05-09 Ratiopharm Gmbh Solid tapentadol in non-crystalline form
US8696719B2 (en) 2010-06-03 2014-04-15 Tarsus Medical Inc. Methods and devices for treating hallux valgus
CA2795923C (en) * 2010-06-30 2018-10-16 Gruenenthal Gmbh Tapentadol for use in the treatment of irritable bowel syndrome
MX341072B (es) * 2010-07-23 2016-08-05 Grünenthal Gmbh * Sales o co-cristales de 3-(3-dimetilamino-1-etil-2-metil-propil)-f enol.
CN101948397A (zh) * 2010-09-07 2011-01-19 天津泰普药品科技发展有限公司 镇痛药他喷他多重要中间体的制备方法
EP3597182A1 (en) 2011-03-04 2020-01-22 Grünenthal GmbH Aqueous pharmaceutical formulation of tapentadol for oral administration
CN103501775A (zh) * 2011-03-04 2014-01-08 格吕伦塔尔有限公司 他喷他多的胃肠外给药
AU2012224954C1 (en) 2011-03-04 2017-04-06 Grünenthal GmbH Semisolid aqueous pharmaceutical composition containing tapentadol
SI2694049T1 (sl) 2011-04-05 2019-01-31 Gruenenthal Gmbh Tapentadol za preprečevanje razvoja kronične bolečine
JP6040219B2 (ja) * 2011-04-05 2016-12-07 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 三叉神経因性痛に伴う疼痛の治療用タペンタドール
HUE049308T2 (hu) 2011-04-29 2020-09-28 Gruenenthal Gmbh Tapentadol alkalmazása depresszió és szorongás megelõzésére és kezelésére
EP2968182B8 (en) * 2013-03-15 2018-07-25 SpecGx LLC Abuse deterrent solid dosage form for immediate release with functional score
EP2845625A1 (en) * 2013-09-04 2015-03-11 Grünenthal GmbH Tapentadol for use in the treatment of fibromyalgia and chronic fatigue syndrome
CN107847471A (zh) 2015-03-27 2018-03-27 格吕伦塔尔有限公司 他喷他多肠胃外给药的稳定制剂
AU2016266432B2 (en) * 2015-05-26 2020-10-22 Laboratorio Medinfar-Produtos Farmacêuticos, S.A. Compositions for use in treating Parkinson's disease and related disorders
WO2017148595A1 (en) 2016-02-29 2017-09-08 Grünenthal GmbH Titration of cebranopadol
PE20190908A1 (es) 2016-09-23 2019-06-26 Gruenenthal Chemie Formulacion estable para la administracion parenteral de tapentadol
WO2021185804A1 (en) 2020-03-16 2021-09-23 Grünenthal GmbH Scored tablet
CA3213818A1 (en) * 2021-03-17 2022-09-22 Actelion Pharmaceuticals Ltd Pharmaceutical dosage system
WO2022234076A1 (en) * 2021-05-07 2022-11-10 Grünenthal GmbH Tapentadol for treating neuropathic pain in covid-19 patients

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4783337A (en) 1983-05-11 1988-11-08 Alza Corporation Osmotic system comprising plurality of members for dispensing drug
US4612008A (en) * 1983-05-11 1986-09-16 Alza Corporation Osmotic device with dual thermodynamic activity
US4765989A (en) 1983-05-11 1988-08-23 Alza Corporation Osmotic device for administering certain drugs
JPS6327805A (ja) 1986-07-21 1988-02-05 Sumitomo Electric Ind Ltd 光フアイバの接続用部材及びそれを用いた接続方法
DE4426245A1 (de) * 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
US6339105B1 (en) * 1999-10-12 2002-01-15 Ortho-Mcneil Pharmaceutical, Inc. Analgesic regimen
PE20030527A1 (es) 2001-10-24 2003-07-26 Gruenenthal Chemie Formulacion farmaceutica con liberacion retardada que contiene 3-(3-dimetilamino-1-etil-2-metil-propil) fenol o una sal farmaceuticamente aceptable del mismo y tabletas para administracion oral que la contienen
PT1572167E (pt) 2002-12-13 2008-10-03 Euro Celtique Sa Regime posológico de buprenorfina papa analgesia
US7413749B2 (en) * 2003-03-11 2008-08-19 Purdue Pharma L.P. Titration dosing regimen for controlled release tramadol
DE102007019417A1 (de) * 2007-04-23 2008-11-13 Grünenthal GmbH Tapentadol zur Schmerzbehandlung bei Arthrose
EP1985292A1 (en) * 2007-04-23 2008-10-29 Grünenthal GmbH Titration of tapentadol

Also Published As

Publication number Publication date
EP2148670B1 (en) 2011-11-23
EP3603630A1 (en) 2020-02-05
US20160074342A1 (en) 2016-03-17
CA2683786A1 (en) 2008-10-30
HRP20120147T1 (hr) 2012-03-31
US11344512B2 (en) 2022-05-31
ATE534378T1 (de) 2011-12-15
WO2008128740A8 (en) 2010-06-17
WO2008128740A1 (en) 2008-10-30
JP5933176B2 (ja) 2016-06-08
KR20180004839A (ko) 2018-01-12
JP2019131598A (ja) 2019-08-08
IL201479A (en) 2016-04-21
KR20150027840A (ko) 2015-03-12
ES2378255T3 (es) 2012-04-10
CY1112320T1 (el) 2015-12-09
PT2148670E (pt) 2012-01-24
SI2148670T1 (sl) 2012-03-30
EP3143993A1 (en) 2017-03-22
RU2472497C2 (ru) 2013-01-20
HK1140940A1 (en) 2010-10-29
JP2018030864A (ja) 2018-03-01
PL2148670T3 (pl) 2012-04-30
EP1985292A1 (en) 2008-10-29
DK2148670T3 (da) 2012-03-12
RU2009142940A (ru) 2011-05-27
AU2008241013B2 (en) 2013-06-20
CA2683786C (en) 2021-10-26
MX2009011444A (es) 2009-11-05
JP2016128468A (ja) 2016-07-14
KR102078999B1 (ko) 2020-02-19
US20190290603A1 (en) 2019-09-26
US20170079938A1 (en) 2017-03-23
US20090012180A1 (en) 2009-01-08
IL201479A0 (en) 2010-05-31
AU2008241013A1 (en) 2008-10-30
CN101730530A (zh) 2010-06-09
ZA200907355B (en) 2010-08-25
KR20100017267A (ko) 2010-02-16
NZ580415A (en) 2012-04-27
EP2148670A1 (en) 2010-02-03
EP2422778A1 (en) 2012-02-29
JP2010531296A (ja) 2010-09-24

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Granted publication date: 20131023

CF01 Termination of patent right due to non-payment of annual fee