CN101711673B - 食道酸碱度无线监测定位系统、装置及方法 - Google Patents
食道酸碱度无线监测定位系统、装置及方法 Download PDFInfo
- Publication number
- CN101711673B CN101711673B CN2009101911951A CN200910191195A CN101711673B CN 101711673 B CN101711673 B CN 101711673B CN 2009101911951 A CN2009101911951 A CN 2009101911951A CN 200910191195 A CN200910191195 A CN 200910191195A CN 101711673 B CN101711673 B CN 101711673B
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- vivo sensing
- transmitting device
- calibration
- microprocessor
- data
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Links
- 238000000034 method Methods 0.000 title claims abstract description 46
- 210000003238 esophagus Anatomy 0.000 title claims abstract description 25
- 238000012544 monitoring process Methods 0.000 title claims abstract description 21
- 238000001727 in vivo Methods 0.000 claims abstract description 147
- 238000000338 in vitro Methods 0.000 claims abstract description 90
- 230000005540 biological transmission Effects 0.000 claims abstract description 8
- 238000001514 detection method Methods 0.000 claims description 84
- 235000014676 Phragmites communis Nutrition 0.000 claims description 37
- 238000005070 sampling Methods 0.000 claims description 32
- 239000002775 capsule Substances 0.000 claims description 29
- 230000008569 process Effects 0.000 claims description 24
- 238000012360 testing method Methods 0.000 claims description 20
- 230000006698 induction Effects 0.000 claims description 7
- 210000001124 body fluid Anatomy 0.000 claims description 3
- 239000010839 body fluid Substances 0.000 claims description 3
- 238000002360 preparation method Methods 0.000 claims 1
- 238000010586 diagram Methods 0.000 description 8
- 238000011282 treatment Methods 0.000 description 4
- 230000009471 action Effects 0.000 description 3
- 238000004891 communication Methods 0.000 description 3
- 238000001914 filtration Methods 0.000 description 3
- 208000021302 gastroesophageal reflux disease Diseases 0.000 description 3
- 210000001035 gastrointestinal tract Anatomy 0.000 description 3
- 238000011084 recovery Methods 0.000 description 3
- 230000000284 resting effect Effects 0.000 description 3
- 230000003321 amplification Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 230000007613 environmental effect Effects 0.000 description 2
- 208000028299 esophageal disease Diseases 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 238000003199 nucleic acid amplification method Methods 0.000 description 2
- 208000000689 peptic esophagitis Diseases 0.000 description 2
- 238000010992 reflux Methods 0.000 description 2
- NDVLTYZPCACLMA-UHFFFAOYSA-N silver oxide Chemical compound [O-2].[Ag+].[Ag+] NDVLTYZPCACLMA-UHFFFAOYSA-N 0.000 description 2
- 208000019505 Deglutition disease Diseases 0.000 description 1
- 208000000461 Esophageal Neoplasms Diseases 0.000 description 1
- 208000007217 Esophageal Stenosis Diseases 0.000 description 1
- 208000000624 Esophageal and Gastric Varices Diseases 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 206010030155 Oesophageal carcinoma Diseases 0.000 description 1
- 206010030194 Oesophageal stenosis Diseases 0.000 description 1
- 229910021607 Silver chloride Inorganic materials 0.000 description 1
- 206010056091 Varices oesophageal Diseases 0.000 description 1
- QJVKUMXDEUEQLH-UHFFFAOYSA-N [B].[Fe].[Nd] Chemical compound [B].[Fe].[Nd] QJVKUMXDEUEQLH-UHFFFAOYSA-N 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- -1 aluminum nickel cobalt Chemical compound 0.000 description 1
- 229910052787 antimony Inorganic materials 0.000 description 1
- WATWJIUSRGPENY-UHFFFAOYSA-N antimony atom Chemical compound [Sb] WATWJIUSRGPENY-UHFFFAOYSA-N 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 201000004101 esophageal cancer Diseases 0.000 description 1
- 208000024170 esophageal varices Diseases 0.000 description 1
- 201000010120 esophageal varix Diseases 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000696 magnetic material Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 229910001172 neodymium magnet Inorganic materials 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000008855 peristalsis Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 description 1
- 229910001923 silver oxide Inorganic materials 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/07—Endoradiosondes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/07—Endoradiosondes
- A61B5/073—Intestinal transmitters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/06—Devices, other than using radiation, for detecting or locating foreign bodies ; Determining position of diagnostic devices within or on the body of the patient
- A61B5/061—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/06—Devices, other than using radiation, for detecting or locating foreign bodies ; Determining position of diagnostic devices within or on the body of the patient
- A61B5/061—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body
- A61B5/062—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body using magnetic field
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14539—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring pH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1495—Calibrating or testing of in-vivo probes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/42—Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
- A61B5/4222—Evaluating particular parts, e.g. particular organs
- A61B5/4233—Evaluating particular parts, e.g. particular organs oesophagus
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04B—TRANSMISSION
- H04B7/00—Radio transmission systems, i.e. using radiation field
- H04B7/24—Radio transmission systems, i.e. using radiation field for communication between two or more posts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0242—Operational features adapted to measure environmental factors, e.g. temperature, pollution
- A61B2560/0247—Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value
- A61B2560/0252—Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value using ambient temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6861—Capsules, e.g. for swallowing or implanting
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Optics & Photonics (AREA)
- Human Computer Interaction (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Computer Networks & Wireless Communication (AREA)
- Signal Processing (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
Priority Applications (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009101911951A CN101711673B (zh) | 2009-10-16 | 2009-10-16 | 食道酸碱度无线监测定位系统、装置及方法 |
| ES10822990.7T ES2668223T3 (es) | 2009-10-16 | 2010-10-15 | Sistema de posicionamiento y método para monitorización inalámbrica del valor del pH esofágico |
| CA2777811A CA2777811C (en) | 2009-10-16 | 2010-10-15 | Positioning system, apparatus, and method for wireless monitoring of esophageal ph value |
| HUE10822990A HUE037789T2 (hu) | 2009-10-16 | 2010-10-15 | Pozicionáló rendszer és eljárás nyelõcsõ pH értékének vezeték nélküli felügyeletére |
| AU2010306359A AU2010306359B2 (en) | 2009-10-16 | 2010-10-15 | Positioning system, apparatus and method for esophageal PH value wireless monitoring |
| KR1020127012487A KR101378751B1 (ko) | 2009-10-16 | 2010-10-15 | Ph 값 무선 모니터링을 위한 포지셔닝 시스템, 장치 및 방법 |
| RU2012116467/14A RU2522970C2 (ru) | 2009-10-16 | 2010-10-15 | Следящая система, аппаратура и способ позиционирования для беспроводного мониторинга уровня ph в пищеводе |
| JP2012533457A JP5739435B2 (ja) | 2009-10-16 | 2010-10-15 | 食道pH値無線監視のための位置決めシステム、装置及び方法 |
| PT108229907T PT2489303T (pt) | 2009-10-16 | 2010-10-15 | Sistema de posicionamento e método para monitorização sem fios do valor do ph esofágico |
| EP10822990.7A EP2489303B1 (en) | 2009-10-16 | 2010-10-15 | Positioning system and method for esophageal ph value wireless monitoring |
| PCT/CN2010/001623 WO2011044758A1 (zh) | 2009-10-16 | 2010-10-15 | 食道酸碱度无线监测定位系统、装置及方法 |
| PL10822990T PL2489303T3 (pl) | 2009-10-16 | 2010-10-15 | System pozycjonowania i sposób bezprzewodowego monitorowania wartości pH przełyku |
| US13/447,322 US20120203084A1 (en) | 2009-10-16 | 2012-04-16 | POSITIONING SYSTEM, APPARATUS, AND METHOD FOR WIRELESS MONITORING OF ESOPHAGEAL pH VALUE |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009101911951A CN101711673B (zh) | 2009-10-16 | 2009-10-16 | 食道酸碱度无线监测定位系统、装置及方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101711673A CN101711673A (zh) | 2010-05-26 |
| CN101711673B true CN101711673B (zh) | 2012-11-21 |
Family
ID=42415960
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009101911951A Active CN101711673B (zh) | 2009-10-16 | 2009-10-16 | 食道酸碱度无线监测定位系统、装置及方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20120203084A1 (enExample) |
| EP (1) | EP2489303B1 (enExample) |
| JP (1) | JP5739435B2 (enExample) |
| KR (1) | KR101378751B1 (enExample) |
| CN (1) | CN101711673B (enExample) |
| AU (1) | AU2010306359B2 (enExample) |
| CA (1) | CA2777811C (enExample) |
| ES (1) | ES2668223T3 (enExample) |
| HU (1) | HUE037789T2 (enExample) |
| PL (1) | PL2489303T3 (enExample) |
| PT (1) | PT2489303T (enExample) |
| RU (1) | RU2522970C2 (enExample) |
| WO (1) | WO2011044758A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101711673B (zh) * | 2009-10-16 | 2012-11-21 | 重庆金山科技(集团)有限公司 | 食道酸碱度无线监测定位系统、装置及方法 |
| GB2476466A (en) * | 2009-12-22 | 2011-06-29 | Ritelite Systems Ltd | Battery monitor for light. |
| CN102670158A (zh) * | 2012-05-10 | 2012-09-19 | 无锡市华焯光电科技有限公司 | 一种可定位胶囊内窥镜系统 |
| GB201210439D0 (en) * | 2012-06-13 | 2012-07-25 | Softcell Medicals | Apparatus |
| EP2890456B1 (en) * | 2012-08-29 | 2019-02-06 | Koninklijke Philips N.V. | Environment and use monitoring system for advanced life support devices |
| GB201304738D0 (en) | 2013-03-15 | 2013-05-01 | Mars Inc | Sampling Device |
| WO2016042300A1 (en) * | 2014-09-17 | 2016-03-24 | Mars, Incorporated | Device |
| CA2961127C (en) | 2014-09-17 | 2023-07-25 | Mars, Incorporated | Sampling device with ejecting compartment |
| WO2016042302A1 (en) * | 2014-09-17 | 2016-03-24 | Mars, Incorporated | Device |
| CN104706307A (zh) * | 2015-03-23 | 2015-06-17 | 朱玉森 | 一种消化道无介入式诊查系统 |
| CN105342543B (zh) * | 2015-09-25 | 2017-06-09 | 重庆金山科技(集团)有限公司 | 食道多参数无线检测胶囊及检测控制系统 |
| CN107625515A (zh) * | 2017-10-10 | 2018-01-26 | 重庆金山医疗器械有限公司 | 食道pH导管恒温校准装置 |
| CN111494186B (zh) * | 2020-06-01 | 2024-01-02 | 上海安翰医疗技术有限公司 | 振动胶囊及其检测方法 |
| US12440121B2 (en) | 2020-08-13 | 2025-10-14 | The Chinese University Of Hong Kong | Apparatus and methods for monitoring concentrations of analytes in body fluid |
| CN112472008A (zh) * | 2020-11-02 | 2021-03-12 | 重庆金山医疗器械有限公司 | 一种ph胶囊定位装置、方法、设备及可读存储介质 |
| CN116448867B (zh) * | 2023-06-16 | 2023-10-20 | 北京市农林科学院智能装备技术研究中心 | 一种瘤胃液酸碱度无线无源传感器及监测系统 |
| CN116784806A (zh) * | 2023-07-28 | 2023-09-22 | 北京航空航天大学 | 基于isfet的单芯片集成微型无线ph检测装置及系统 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2066554C1 (ru) * | 1996-01-18 | 1996-09-20 | Акционерное общество открытого типа "Завод "Компонент" | Электростимулятор желудочно-кишечного тракта |
| JP2000111506A (ja) * | 1998-10-07 | 2000-04-21 | Toa Electronics Ltd | メモリー付き計測装置 |
| US20030040665A1 (en) * | 1999-05-28 | 2003-02-27 | E-Monitors, Inc. | Systems and methods of pH tissue monitoring |
| EP1578246B1 (en) * | 2001-07-12 | 2014-09-03 | Given Imaging Ltd. | Device for examining a body lumen |
| US6846994B2 (en) * | 2001-09-19 | 2005-01-25 | Justin B. Wenner | System and method to delay closure of a normally closed electrical circuit |
| JP3756797B2 (ja) * | 2001-10-16 | 2006-03-15 | オリンパス株式会社 | カプセル型医療機器 |
| RU30589U1 (ru) * | 2002-12-09 | 2003-07-10 | ФГУ Омская государственная медицинская академия | Зонд для комплексной оценки параметров верхних отделов желудочно-кишечного тракта (жкт) |
| JP4012097B2 (ja) * | 2003-03-06 | 2007-11-21 | オリンパス株式会社 | カプセル型医療装置回収装置 |
| JP2005253798A (ja) * | 2004-03-12 | 2005-09-22 | Olympus Corp | 被検体内導入装置 |
| DE602005007847D1 (de) * | 2004-12-30 | 2008-08-14 | Given Imaging Ltd | System zur Lokalisation einer in-Vivo Signalquelle |
| JP2008529631A (ja) * | 2005-02-11 | 2008-08-07 | ザ ユニバーシティー コート オブ ザ ユニバーシティー オブ グラスゴー | 検査デバイス、検査装置及び検査システム、並びにそれらの駆動方法 |
| US20060231110A1 (en) * | 2005-03-24 | 2006-10-19 | Mintchev Martin P | Ingestible capsule for esophageal monitoring |
| JP4848851B2 (ja) * | 2006-06-15 | 2011-12-28 | パナソニック株式会社 | 生体検査システム |
| JP4373415B2 (ja) * | 2006-07-05 | 2009-11-25 | オリンパスメディカルシステムズ株式会社 | 生体内情報取得装置 |
| US9675285B2 (en) * | 2006-10-16 | 2017-06-13 | Given Imaging Ltd. | Delivery device for implantable monitor |
| US8187174B2 (en) * | 2007-01-22 | 2012-05-29 | Capso Vision, Inc. | Detection of when a capsule camera enters into or goes out of a human body and associated operations |
| JP4936528B2 (ja) * | 2007-03-28 | 2012-05-23 | 富士フイルム株式会社 | カプセル内視鏡システム、およびカプセル内視鏡システムの作動方法 |
| JP5065812B2 (ja) * | 2007-08-29 | 2012-11-07 | オリンパスメディカルシステムズ株式会社 | 生体内画像取得装置および生体内画像取得システム |
| CN101108122A (zh) * | 2007-08-30 | 2008-01-23 | 上海交通大学 | 永磁定位式胃肠道pH值24小时无创监测系统 |
| CA2724890A1 (en) * | 2008-06-18 | 2009-12-23 | The Smartpill Corporation | System and method of evaluating a subject with an ingestible capsule |
| CN101406410A (zh) * | 2008-10-28 | 2009-04-15 | 重庆金山科技(集团)有限公司 | 食道内无创固定体内微型装置的系统 |
| CN201275065Y (zh) * | 2008-10-28 | 2009-07-22 | 重庆金山科技(集团)有限公司 | 食道酸碱度无线监测系统 |
| CN101711673B (zh) * | 2009-10-16 | 2012-11-21 | 重庆金山科技(集团)有限公司 | 食道酸碱度无线监测定位系统、装置及方法 |
| CN201505133U (zh) * | 2009-10-16 | 2010-06-16 | 重庆金山科技(集团)有限公司 | 食道酸碱度无线监测定位系统及装置 |
-
2009
- 2009-10-16 CN CN2009101911951A patent/CN101711673B/zh active Active
-
2010
- 2010-10-15 PT PT108229907T patent/PT2489303T/pt unknown
- 2010-10-15 AU AU2010306359A patent/AU2010306359B2/en not_active Ceased
- 2010-10-15 WO PCT/CN2010/001623 patent/WO2011044758A1/zh not_active Ceased
- 2010-10-15 EP EP10822990.7A patent/EP2489303B1/en active Active
- 2010-10-15 KR KR1020127012487A patent/KR101378751B1/ko not_active Expired - Fee Related
- 2010-10-15 ES ES10822990.7T patent/ES2668223T3/es active Active
- 2010-10-15 CA CA2777811A patent/CA2777811C/en active Active
- 2010-10-15 PL PL10822990T patent/PL2489303T3/pl unknown
- 2010-10-15 JP JP2012533457A patent/JP5739435B2/ja not_active Expired - Fee Related
- 2010-10-15 RU RU2012116467/14A patent/RU2522970C2/ru active
- 2010-10-15 HU HUE10822990A patent/HUE037789T2/hu unknown
-
2012
- 2012-04-16 US US13/447,322 patent/US20120203084A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2777811A1 (en) | 2011-04-21 |
| HUE037789T2 (hu) | 2018-09-28 |
| WO2011044758A1 (zh) | 2011-04-21 |
| RU2012116467A (ru) | 2013-11-27 |
| RU2522970C2 (ru) | 2014-07-20 |
| JP2013507203A (ja) | 2013-03-04 |
| AU2010306359A1 (en) | 2012-05-10 |
| JP5739435B2 (ja) | 2015-06-24 |
| KR101378751B1 (ko) | 2014-04-04 |
| KR20120112399A (ko) | 2012-10-11 |
| PL2489303T3 (pl) | 2018-10-31 |
| EP2489303A4 (en) | 2017-02-22 |
| PT2489303T (pt) | 2018-06-28 |
| CA2777811C (en) | 2017-06-13 |
| AU2010306359B2 (en) | 2014-01-16 |
| ES2668223T3 (es) | 2018-05-17 |
| US20120203084A1 (en) | 2012-08-09 |
| EP2489303B1 (en) | 2018-03-28 |
| EP2489303A1 (en) | 2012-08-22 |
| CN101711673A (zh) | 2010-05-26 |
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