CN101711251A - 1β-甲基碳青霉烯抗生素及其药物组合物和用途 - Google Patents
1β-甲基碳青霉烯抗生素及其药物组合物和用途 Download PDFInfo
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- CN101711251A CN101711251A CN200880019477A CN200880019477A CN101711251A CN 101711251 A CN101711251 A CN 101711251A CN 200880019477 A CN200880019477 A CN 200880019477A CN 200880019477 A CN200880019477 A CN 200880019477A CN 101711251 A CN101711251 A CN 101711251A
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- CN
- China
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- bases
- yue
- methyl
- hydrogen atom
- represent hydrogen
- Prior art date
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
式(I)所示的1β-甲基碳青霉烯抗生素、其药学上可接受的盐、易水解的酯或异构体、这些化合物的制备方法、含有这些化合物的药物组合物以及这些化合物用于制备治疗和/或预防包括人在内的哺乳动物中感染性疾病的药物的用途。
Description
PCT国内申请，说明书已公开。
Claims (1)
- PCT国内申请，权利要求书已公开。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008800194777A CN101711251B (zh) | 2007-06-26 | 2008-06-26 | 1β-甲基碳青霉烯抗生素及其药物组合物和用途 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007100166079A CN101333217A (zh) | 2007-06-26 | 2007-06-26 | 1-甲基碳青霉烯抗生素 |
| CN200710016607.9 | 2007-06-26 | ||
| CN2008800194777A CN101711251B (zh) | 2007-06-26 | 2008-06-26 | 1β-甲基碳青霉烯抗生素及其药物组合物和用途 |
| PCT/CN2008/001238 WO2009000163A1 (fr) | 2007-06-26 | 2008-06-26 | ANTIBIOTIQUES DE TYPE 1β-MÉTHYLCARBAPÉNÈME, COMPOSITIONS PHARMACEUTIQUES ET LEUR UTILISATION |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101711251A true CN101711251A (zh) | 2010-05-19 |
| CN101711251B CN101711251B (zh) | 2011-12-28 |
Family
ID=40185183
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2007100166079A Pending CN101333217A (zh) | 2007-06-26 | 2007-06-26 | 1-甲基碳青霉烯抗生素 |
| CN2008800194777A Active CN101711251B (zh) | 2007-06-26 | 2008-06-26 | 1β-甲基碳青霉烯抗生素及其药物组合物和用途 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2007100166079A Pending CN101333217A (zh) | 2007-06-26 | 2007-06-26 | 1-甲基碳青霉烯抗生素 |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JP2010531308A (zh) |
| CN (2) | CN101333217A (zh) |
| WO (1) | WO2009000163A1 (zh) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010077976A2 (en) | 2008-12-17 | 2010-07-08 | The Regents Of The University Of California | Prokineticin receptor antagonists and uses thereof |
| CN101817837A (zh) * | 2009-02-13 | 2010-09-01 | 山东轩竹医药科技有限公司 | 含有氮杂双环的碳青霉烯衍生物 |
| US8318716B2 (en) * | 2009-12-31 | 2012-11-27 | Kbp Biosciences Co., Ltd. | Carbapenem derivatives |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1283906C (en) * | 1983-05-09 | 1991-05-07 | Makoto Sunagawa | .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF |
| US5554606A (en) * | 1990-03-12 | 1996-09-10 | Zeneca Limited | Antibiotic compounds |
| GB9107341D0 (en) * | 1991-04-08 | 1991-05-22 | Ici Plc | Antibiotic compounds |
-
2007
- 2007-06-26 CN CNA2007100166079A patent/CN101333217A/zh active Pending
-
2008
- 2008-06-26 CN CN2008800194777A patent/CN101711251B/zh active Active
- 2008-06-26 WO PCT/CN2008/001238 patent/WO2009000163A1/zh active Application Filing
- 2008-06-26 JP JP2010513622A patent/JP2010531308A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN101333217A (zh) | 2008-12-31 |
| JP2010531308A (ja) | 2010-09-24 |
| WO2009000163A1 (fr) | 2008-12-31 |
| CN101711251B (zh) | 2011-12-28 |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
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| TR01 | Transfer of patent right |
Effective date of registration: 20190320 Address after: 570105 Tianyi International Building, 85 Binhai Avenue, Longhua District, Haikou City, Hainan Province, 27th Floor Patentee after: Hainan Xuanzhu Pharmaceutical Technology Co., Ltd. Address before: 250101 No. 2518 Tianchen Street, Jinan Hi-tech Development Zone, Shandong Province Patentee before: Shandong Xuanzhu Medical Technology Co., Ltd. |
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| CP03 | Change of name, title or address | ||
| CP03 | Change of name, title or address |
Address after: 050000 Beijing Tianjin Hebei Collaborative Innovation Demonstration Park, 769 Taihang street, high tech Zone, Shijiazhuang City, Hebei Province 203c507 Patentee after: Xuanzhu Biotechnology Co., Ltd Address before: 570105 Tianyi International Building, 85 Binhai Avenue, Longhua District, Haikou City, Hainan Province, 27th Floor Patentee before: Hainan Xuanzhu Pharma Co.,Ltd. |
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| CP01 | Change in the name or title of a patent holder |
Address after: 050000 Beijing Tianjin Hebei Collaborative Innovation Demonstration Park 203c507, 769 Taihang street, high tech Zone, Shijiazhuang City, Hebei Province Patentee after: Xuanzhu Biotechnology Co.,Ltd. Address before: 050000 Beijing Tianjin Hebei Collaborative Innovation Demonstration Park 203c507, 769 Taihang street, high tech Zone, Shijiazhuang City, Hebei Province Patentee before: Xuanzhu Biotechnology Co.,Ltd. |