CN101708216A - Method for processing vinegar schisandra fruit - Google Patents
Method for processing vinegar schisandra fruit Download PDFInfo
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- CN101708216A CN101708216A CN200910264893A CN200910264893A CN101708216A CN 101708216 A CN101708216 A CN 101708216A CN 200910264893 A CN200910264893 A CN 200910264893A CN 200910264893 A CN200910264893 A CN 200910264893A CN 101708216 A CN101708216 A CN 101708216A
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- vinegar
- schisandra fruit
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- fructus schisandrae
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- 235000021419 vinegar Nutrition 0.000 title claims abstract description 58
- 239000000052 vinegar Substances 0.000 title claims abstract description 58
- 238000000034 method Methods 0.000 title claims abstract description 36
- 235000008422 Schisandra chinensis Nutrition 0.000 title claims abstract description 24
- 240000006079 Schisandra chinensis Species 0.000 title claims description 15
- 235000013399 edible fruits Nutrition 0.000 title abstract description 13
- 238000012545 processing Methods 0.000 title abstract description 5
- 239000000463 material Substances 0.000 claims abstract description 16
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- 235000009566 rice Nutrition 0.000 claims abstract description 15
- 238000001035 drying Methods 0.000 claims abstract description 13
- 238000010025 steaming Methods 0.000 claims description 40
- 239000012567 medical material Substances 0.000 claims description 13
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- 238000013461 design Methods 0.000 claims description 4
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- 239000003814 drug Substances 0.000 abstract description 8
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- YEFOAORQXAOVJQ-RZFZLAGVSA-N schisandrol a Chemical compound C1[C@H](C)[C@@](C)(O)CC2=CC(OC)=C(OC)C(OC)=C2C2=C1C=C(OC)C(OC)=C2OC YEFOAORQXAOVJQ-RZFZLAGVSA-N 0.000 abstract description 6
- YEFOAORQXAOVJQ-UHFFFAOYSA-N wuweizischun A Natural products C1C(C)C(C)(O)CC2=CC(OC)=C(OC)C(OC)=C2C2=C1C=C(OC)C(OC)=C2OC YEFOAORQXAOVJQ-UHFFFAOYSA-N 0.000 abstract description 5
- 238000004519 manufacturing process Methods 0.000 abstract description 4
- 150000004676 glycans Chemical class 0.000 abstract description 3
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- 238000005265 energy consumption Methods 0.000 abstract 1
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- 238000003672 processing method Methods 0.000 abstract 1
- 239000000047 product Substances 0.000 description 54
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- RTZKSTLPRTWFEV-UHFFFAOYSA-N Isokadsuranin Natural products COC1=C2C=3C(OC)=C(OC)C(OC)=CC=3CC(C)C(C)CC2=CC2=C1OCO2 RTZKSTLPRTWFEV-UHFFFAOYSA-N 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
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- CMSMOCZEIVJLDB-UHFFFAOYSA-N Cyclophosphamide Chemical compound ClCCN(CCCl)P1(=O)NCCCO1 CMSMOCZEIVJLDB-UHFFFAOYSA-N 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
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- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a method for processing vinegar schisandra fruit, which can effectively prepare medicinal material of the schisandra fruit into vinegar schisandra fruit medical herb in pieces. The invention has the concrete technical scheme comprises the following steps: taking the medicinal material of the schisandra fruit, removing the non-medicinal parts such as fruit stalks, stumps and the like, adding rice vinegar, decompressing and moistening until the rice vinegar is sucked up, braising at high pressure, drying and packaging so as to obtain the vinegar schisandra fruit. The method is simple and easy to operate, the color of the prepared vinegar schisandra fruit is uniform, and the indexes of the contents of water content, ash content and the like are all within a range specified by a dispensatory; compared with a normal-pressure vinegar braising product of the vinegar schisandra fruit, no obvious difference exists in the contents of general lignanoid, schisandrol A, schisandra fruit essence B and general organic acid; compared with the normal-pressure vinegar braising product, the contents of 5-hydroxymethyl furfural and general polysaccharide are higher; and compared with a traditional normal-pressure braising process, the processing method adopting high-pressure vinegar braising lowers energy consumption and saves time. Therefore, the invention can be popularized and used for large-scale production, provides concrete technical data for the processing of the vinegar schisandra fruit and provides ground for the execution of the standardized production operation rule of traditional Chinese medicine medical herb in pieces.
Description
One, technical field
The invention belongs to technical field of Chinese medicines, relate to a kind of concocting method of Chinese medicine, specifically relate to by a kind of concocting method for preparing Fructus Schisandrae Chinensis (processed with vinegar) of Fructus Schisandrae Chinensis through moistening under pressure with vinegar, high pressure steaming.
Two, technical background
Fructus Schisandrae Chinensis is the dry mature fruit of magnoliaceae schisandra Schisandra chinesis (Turcz.) Baill., and main product claims Radix Schisandrae Bicoloris in China the Northeast so practise.Fructus Schisandrae Sphenantherae is the dry mature fruit of Magnoliacea plant schisandra chinensis Schisandra sphenanthera Rehd.Et Wils..Restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.Be used for the chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, the deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.The property enhancing of sour and astringent convergence after the vinegar system, the arresting seminal emission anti-diarrhea effect is stronger.Be used for seminal emission, have loose bowels.About the concocting method of the modern main literature record of Fructus Schisandrae Chinensis have that clean system, steaming with vinegar, wine steam, four kinds of processed with honey methods, " Chinese pharmacopoeia version in 2005 concocting method that Fructus Schisandrae Chinensis is recorded has steaming with vinegar a kind of.Fructus Schisandrae Chinensis (processed with vinegar): get clean Fructus Schisandrae Chinensis, steam to black according to steaming with vinegar method (appendix II D).Time spent smashs to pieces.The rational technic index of its concocting method neither one, steaming time, with the amount of vinegar, all less than control, wherein steaming time is approximately 1～2 day, and is consuming time longer for the condition that steams and temperature or the like, and technology is loaded down with trivial details relatively, has greatly restricted industrialized great production.Therefore, but the Fructus Schisandrae Chinensis processing procedure parameter of the practical quantified controlling of formulation, and reasonably prepared slice quality is investigated index, and is imperative.
Three, summary of the invention
At the requirement of above-mentioned situation and country, the present invention is directed to the technological parameter that each link is concocted in Fructus Schisandrae Chinensis (processed with vinegar) processing, carried out orthogonal optimum seeking, obtained the optimum process condition of preparation Fructus Schisandrae Chinensis (processed with vinegar).
The object of the present invention is to provide a kind of concocting method of Fructus Schisandrae Chinensis (processed with vinegar).
The object of the invention realizes by following technical scheme:
1, a kind of concocting method of Fructus Schisandrae Chinensis (processed with vinegar), it is as follows to it is characterized in that concocting step:
(1) gets schisandra chinensis medicinal material, remove dis-medicinal parts such as carpopodium and residual stem, get an amount of adjuvant rice vinegar, add in the schisandra chinensis medicinal material and mix thoroughly, till decompression moistening to rice vinegar is exhausted by medical material;
(2) put in the high pressure steaming equipment, airtight, steam with the high pressure steaming method, treat to take out when pressure is reduced to normal pressure;
(3) put in the drying equipment, be dried to that moisture is when 7%-13% in the medical material, taking-up cools, and packs, promptly.
The amount that adds the adjuvant rice vinegar in the above-mentioned steps (1) is the rice vinegar that is equivalent to 20% weight of schisandra chinensis medicinal material weight, places hermetic container, is decompressed to 0.04～0.08MPa, keeps 0.5～1 hour, recovers normal pressure again.
The high pressure steaming method of above-mentioned steps (2) is that medical material is placed high pressure steaming the medicinal hebrs equipment, and design temperature is 110 ℃～130 ℃, under 0.14MPa～0.16MPa, continues to steam 1～2 hour.
Drying equipment is heated-air circulation oven or open type superconductive energy-saving drying machine in the above-mentioned steps (3), and the drying machine design temperature is 50 ℃, and be 5 hours drying time.
This concocting method is simple, easy operating, the Fructus Schisandrae Chinensis (processed with vinegar) color and luster that makes, moisture all within the scope of pharmacopeia regulation, are compared with traditional concocting method, greatly shortened the time that steams, be fit to big production operation, can effectively satisfy clinical needs, improve clinical efficacy the Fructus Schisandrae Chinensis (processed with vinegar) decoction pieces, the process of preparing Chinese medicine for Fructus Schisandrae Chinensis (processed with vinegar) simultaneously provides concrete technological parameter, and carries out the authentication code system for the prepared slices of Chinese crude drugs foundation is provided.
Four, the specific embodiment
Below in conjunction with embodiment the specific embodiment of the present invention is elaborated.
The concocting method of 1. 1 kinds of Fructus Schisandrae Chinensis (processed with vinegar) of embodiment
Get schisandra chinensis medicinal material 100g, remove dis-medicinal parts such as carpopodium and residual stem, get the adjuvant rice vinegar of 20g, add in the schisandra chinensis medicinal material and mix thoroughly, place hermetic container, be decompressed to 0.04MPa, kept 0.5 hour, after recovering normal pressure, take out, put in the high pressure steaming the medicinal hebrs equipment, airtight, under 130 ℃, high pressure steaming is after 1 hour, treat to take out after pressure is reduced to normal pressure, put in the heated-air circulation oven, 50 ℃ were dried to down in the medical material moisture in dry 5 hours at 7%～13% o'clock, taking-up cools, and packs, promptly.
The concocting method of 2. 1 kinds of Fructus Schisandrae Chinensis (processed with vinegar) of embodiment
Get schisandra chinensis medicinal material 50kg, remove dis-medicinal parts such as carpopodium and residual stem, get the adjuvant rice vinegar of 10kg, add in the schisandra chinensis medicinal material and mix thoroughly, place hermetic container, be decompressed to 0.08MPa, kept 1 hour, and behind the recovery normal pressure, took out, put in the high pressure steaming the medicinal hebrs equipment, under 110 ℃, high pressure steaming is after 2 hours, treat to take out after pressure is reduced to normal pressure, put in the heated-air circulation oven, 50 ℃ were dried to down in the medical material moisture in dry 5 hours at 7%～13% o'clock, taking-up cools, and packs, promptly.
The concocting method of 3. 1 kinds of Fructus Schisandrae Chinensis (processed with vinegar) of embodiment
Get schisandra chinensis medicinal material 100g, remove dis-medicinal parts such as carpopodium and residual stem, get the adjuvant rice vinegar of 20g, add in the schisandra chinensis medicinal material and mix thoroughly, place hermetic container, be decompressed to 0.08MPa, kept 1 hour, and behind the recovery normal pressure, took out, put in the high pressure steaming the medicinal hebrs equipment, under 110 ℃, high pressure steaming is after 2 hours, treat to take out after pressure is reduced to normal pressure, put in the open type superconductive energy-saving drying machine, 50 ℃ were dried to down in the medical material moisture in dry 5 hours at 7%～13% o'clock, taking-up cools, and packs, promptly.
The concocting method of 4. 1 kinds of Fructus Schisandrae Chinensis (processed with vinegar) of embodiment
Get schisandra chinensis medicinal material 50kg, remove dis-medicinal parts such as carpopodium and residual stem, get the adjuvant rice vinegar of 10kg, add in the schisandra chinensis medicinal material and mix thoroughly, place hermetic container, be decompressed to 0.04MPa, kept 0.5 hour, and behind the recovery normal pressure, took out, put in the high pressure steaming the medicinal hebrs equipment, airtight, under 130 ℃, high pressure steaming is after 1 hour, treat to take out after pressure is reduced to normal pressure, put in the open type superconductive energy-saving drying machine, 50 ℃ were dried in the medical material down that moisture was at 7%～13% o'clock in dry 5 hours, and taking-up cools, pack, promptly.
The comparative test of active constituent content in the different processed products of embodiment 5. Fructus Schisandrae Chinensis
This experiment adopt respectively spectrophotography with the high performance liquid chromatography comparative measurements contained total lignans in the different processed products of Fructus Schisandrae Chinensis, the content of schisandrin, schisandrin B and 5 hydroxymethyl furfural.From component content, the different processed product of Fructus Schisandrae Chinensis is comprehensively analyzed comparison, for the concocted specification research of Fructus Schisandrae Chinensis provides certain scientific evidence.
Total lignans in the different processed products of Fructus Schisandrae Chinensis, the content of schisandrin, schisandrin B and 5 hydroxymethyl furfural relatively
The mensuration of total lignans: the about 0.2g of sample thief powder (crossing sieve No. three), the accurate title, decide, and puts in the 25ml measuring bottle, adds the about 23ml of methanol, and ultrasonic (power 250W, frequency 20kHz) extracted 20 minutes, took out, and added methanol to scale, shook up, and filtered, promptly.Accurate test sample liquid, reference substance liquid, each 0.6ml of methanol of drawing, put respectively in the three brace plug test tubes, fling to methanol, accurate respectively again 10% chromotropic acid clear aqueous solution 0.5ml, sulphuric acid 3ml, the water 1.5ml of adding, shake up, put in the boiling water bath and heated 30 minutes, cooling is a blank with above-mentioned methanol pipe rapidly, according to spectrophotography, measure trap at the wavelength place of 570nm respectively, calculate, promptly.The results are shown in Table 1.
The content assaying method of schisandrin: precision takes by weighing the about 0.2g of three kinds of Fructus Schisandrae Chinensis processed product powder (crossing sieve No. three) respectively, the accurate title in the fixation 25ml measuring bottle, add the about 23ml of methanol, supersound process (power 250W, frequency 2kHz) 20min takes out, add methanol to scale, shake up, filter, filtrate is as need testing solution.Get 10 μ l and inject Kromasil C
18In the chromatographic column, methanol-water (13: 7) is a mobile phase, detects wavelength: 250nm, volume flow: 1ml/min, column temperature: 30 ℃; Measure peak area, calculate content.The results are shown in Table 1.
The assay of schisandrin B: precision takes by weighing the about 0.2g of three kinds of Fructus Schisandrae Chinensis processed product powder (crossing sieve No. three) respectively, the accurate title in the fixation 25ml measuring bottle, add the about 23ml of methanol, supersound process (power 250W, frequency 2kHz) 20min, take out, add methanol to scale, shake up, filter, filtrate is got 10 μ l and is injected Kromasil C as need testing solution
18In the chromatographic column, methanol-water (80: 20) is a mobile phase, and the detection wavelength is 254nm; Volume flow is 1ml/min; Column temperature is 30 ℃, measures peak area, calculates content.The results are shown in Table 1.
The assay of 5 hydroxymethyl furfural in the sample: precision takes by weighing the about 0.2g of three kinds of Fructus Schisandrae Chinensis processed product powder (crossing sieve No. three) respectively, the accurate title in the fixation 25ml measuring bottle, add the about 23ml of methanol, supersound process (power 250W, frequency 2kHz) 20min takes out, add methanol to scale, shake up, filter, filtrate is as need testing solution.Get 10 μ l and inject Kromasil C
18Chromatographic column, acetonitrile-water (95: 5) is a mobile phase, detects wavelength: 284nm, volume flow: 1ml/min, column temperature: 30 ℃, measure peak area, calculate content.The results are shown in Table 1.
Total lignans content (n=3) in the table 1 Fructus Schisandrae Chinensis sample
Experimental result shows that the content difference of total lignans is little in each processed product of Fructus Schisandrae Chinensis, and high pressure steams Fructus Schisandrae Chinensis (processed with vinegar) steams total lignans in the Fructus Schisandrae Chinensis (processed with vinegar) than normal pressure content height.Fructus Schisandrae Chinensis is after concocting, and the content of schisandrin is improved to some extent, and the content of normal pressure steaming Fructus Schisandrae Chinensis (processed with vinegar) and high pressure steaming Fructus Schisandrae Chinensis (processed with vinegar) is close; The content difference of schisandrin B is little in three kinds of different processed products, and high pressure steams Fructus Schisandrae Chinensis (processed with vinegar) content and slightly descends.The content of 5 hydroxymethyl furfural is considerably less in the Fructus Schisandrae Chinensis, but through after steaming, content has improved a lot, and wherein the content of streaming under pressure with vinegar Fructus Schisandrae Chinensis is than the content height of the Fructus Schisandrae Chinensis of normal pressure steaming with vinegar.Having produced 5 hydroxymethyl furfural after the Fructus Schisandrae Chinensis steaming with vinegar system, inferred by the generation condition of 5 hydroxymethyl furfural, may be that Fructus Schisandrae Chinensis itself contains lot of organic acids, and a sour environment is provided, and polysaccharide is decomposed produce 5 hydroxymethyl furfural.
The different processed product pharmacological evaluation of embodiment 6. Fructus Schisandrae Chinensis
1. different processed products are regulated immunologic function relatively
Get 90 of 18～22g cleaning level Kunming kind white mice, be divided into 9 groups at random, 10 every group.Male and female half and half are respectively: 1. blank group: normal saline is model group 2.: normal saline is positive controls 3.: 4. the Lentinula edodes mycelium polysaccharide medicinal liquid gives birth to product group I: give birth to product decocting liquid and 5. give birth to product group II: life product decocting liquid 6. normal pressure steams product group I: normal pressure steam product decocting liquid 7. normal pressure steam product group II: normal pressure steams 8. high pressure steaming product group I of product decocting liquid: high pressure steaming product decocting liquid is high pressure steaming product group II 9.: high pressure steaming product decocting liquid.
Each organizes gastric infusion 1 time every day, continuous 8 days.Model group and administration group are at the 1st day intraperitoneal injection of cyclophosphamide 100mg/kg of administration, for three days on end.30min after the administration of mice last, the india ink 0.1ml/10g of tail vein injection 20% immediately, in 2min and 20min respectively eye socket get blood 20 μ L, be dissolved in 0.1%Na
2CO
3Shake up among the solution 5ml, in 680nm place, 0.1%Na
2CO
3Trap is measured in the solution zeroing, calculates and cleans up index K.Put to death mice, get liver, spleen, thymus and weigh, index and spleen index and thymus index be respectively by the mg number of every 10g body weight spleen and thymus, calculating phagocytic index α.The results are shown in Table 2
The different processed product decocting of table 2 Fructus Schisandrae Chinensis liquid to the immunocompromised effect of immunologic function (x ± s, n=10)
Compare with the blank group
1)Compare with model group P＜0.01
2)P＜0.05,
3)P＜0.01 is compared with the same dosage product of giving birth to
4)P＜0.01
1)P＜0.01vs?blank?group，
2)P＜0.05，
3)P＜0.01vs?model?group，
4)P＜0.01?vs?thesame?dose?of?raw?group
Experimental result shows: model group and blank group relatively have significant difference; Positive drug group and model group relatively have significant difference; Giving birth to product low dose group and model group comparison thymus index has significant difference (P＜0.05), life product high dose group clean up the exponential sum thymus index and model group more all has utmost point significant difference (P＜0.01), phagocytic index has significant difference (P＜0.05); Clean up index, phagocytic index and model group that normal pressure steams high low dose group more all have utmost point significant difference (P＜0.01), and clean up index utmost point significant difference (P＜0.01) is arranged with comparing with the living product group of dosage; High pressure steam high low dose group clean up index and model group relatively has utmost point significant difference (P＜0.01), and with compared utmost point significant difference (P＜0.01) with the living product group of dosage; The thymus index of normal pressure steaming and high pressure steaming high dose group is compared with the living product group of same dosage all has utmost point significant difference (P＜0.01); Normal pressure steams and high pressure steams between the high low dose group each index there are no significant difference.
2. different processed product benefiting actions relatively
Get 90 of 18～22g cleaning level Kunming kind white mice, be divided into 9 groups at random, every group 10, male and female half and half are respectively: 1. blank group: normal saline is model group 2.: normal saline is positive controls 3.: 4. the LIUWEI DIHUANG WAN medicinal liquid gives birth to product group I: give birth to product decocting liquid and 5. give birth to product group II: life product decocting liquid 6. normal pressure steams product group I: normal pressure steam product decocting liquid 7. normal pressure steam product group II: normal pressure steams 8. high pressure steaming product group I of product decocting liquid: high pressure steaming product decocting liquid is high pressure steaming product group II 9.: high pressure steaming product decocting liquid.
Each organizes every day by 20ml/kg dosage gastric infusion 1 time, continuous 11 days.Except that the blank group, other is organized in the 7th day subcutaneous injection hydrocortisone 50mg/kg of administration, continuous 4 days.
(rotating speed 12 changes/min), selects for use the animal that stops on the rod more than the 3min, and 1h after the last administration measures in the 5min by rotating rods method and respectively to organize the number of times that mice falls from rod to observe influence to the deficiency of the kidney yin mouse anti-reflecting fatigue with rotating rods method.The results are shown in Table 3.
Behind the last administration 1h, mouse orbit is got blood, and the centrifugal 10min of 3000r/min gets serum according to requiring to detect the total superoxide dismutase of serum (SOD), malonaldehyde (MDA) on the test kit description.The results are shown in Table 3
The different processed product decocting of table 3 Fructus Schisandrae Chinensis liquid to the influence of deficiency of the kidney yin model mice (x ± s, n=10)
Compare with the blank group
1)P＜0.05,
2)Compare with model group P＜0.01
3)P＜0.05,
4)P＜0.01 is compared with the same dosage product of giving birth to
5)P＜0.05,
6)P＜0.01,
1)P＜0.05,
2)P＜0.01vs blank group,
3)P＜0.05,
4)P＜0.01vs model group,
5)P＜0.05,
6)P＜0.01vs the same dose of raw group
Deficiency of the kidney yin mice transfer rod endurance experimental result shows: model group relatively has significant difference with blank group, positive drug group, high pressure Fructus Schisandrae Chinensis (steamed) high dose group and model group relatively have significant difference (P＜0.05), the product of giving birth to group is compared there was no significant difference with model group, and high pressure Fructus Schisandrae Chinensis (steamed) group relatively has utmost point significant difference (P＜0.01) with the product of giving birth to group; Normal pressure Fructus Schisandrae Chinensis (steamed) high dose group is with the product of giving birth to relatively have significant difference (P＜0.05) with dosage, but compares there was no significant difference with model group; Other each group also there are no significant difference.
SOD vigor, the experiment of MDA assay show in the deficiency of the kidney yin mice serum: in SOD measures: model group relatively has significant difference (P＜0.05) with blank group; Positive drug group, normal pressure steaming and high pressure Fructus Schisandrae Chinensis (steamed) high dose group and model group relatively have significant difference; Other each group there are no significant difference.In MDA measured: model group relatively had significant difference with blank group; Positive drug group, low, the high dose group of giving birth to product, normal pressure steaming, high pressure Fructus Schisandrae Chinensis (steamed) and model group more all have utmost point significant difference (P＜0.01).And normal pressure steams and the high pressure difference of steaming that there are no significant between the high low dose group in SOD, MDA measure.
The result shows: the different processed product decocting of Fructus Schisandrae Chinensis liquid all has potentiation to the non-specific immunity of immunocompromised mice, can resist the fatigue effect of deficiency of the kidney yin mice and improve its SOD vigor, reduce the content of its MDA, and the effect of vinegar product is stronger more obvious.Normal pressure Fructus Schisandrae Chinensis (steamed with vinegar), streaming under pressure with vinegar Fructus Schisandrae Chinensis all can strengthen the drug effect relevant with benefiting action, and both tonification effects all do not have significant difference, and the product of giving birth to of both and same dosage relatively, the effect enhancing.Prompting effectively is a principle with clinical drug safety, during as benefiting action, is good with the vinegar product.
Claims (4)
1. the concocting method of a Fructus Schisandrae Chinensis (processed with vinegar), it is as follows to it is characterized in that concocting step:
(1) gets schisandra chinensis medicinal material, remove dis-medicinal parts such as carpopodium and residual stem, get an amount of adjuvant rice vinegar, add in the schisandra chinensis medicinal material and mix thoroughly, place hermetic container, till decompression moistening to rice vinegar is exhausted by medical material;
(2) above-mentioned medical material is put in the high pressure steaming equipment, airtight, carry out high pressure steaming, treat to take out when pressure is reduced to normal pressure;
(3) medical material that takes out is put in the drying equipment, be dried to that moisture is when 7%-13% in the medical material, taking-up cools, and packs, promptly.
2. according to the described concocting method of claim 1, it is characterized in that the amount at the adding adjuvant rice vinegar described in the step (1) is the rice vinegar that is equivalent to 20% weight of schisandra chinensis medicinal material weight, place hermetic container, be decompressed to 0.04～0.08MPa with the decompression cold-maceration, kept 0.5～1 hour, recover normal pressure again, till moistening to rice vinegar is exhausted by medical material.
3. according to the described concocting method of claim 1, it is characterized in that in the high pressure steaming method described in the step (2) be that medical material is placed high pressure steaming the medicinal hebrs equipment, design temperature is 110～130 ℃, under 0.14MPa～0.16MPa, continues to steam 1～2 hour.
4. according to the described concocting method of claim 1, it is characterized in that at the drying equipment described in the step (3) be heated-air circulation oven or open type superconductive energy-saving drying machine, the drying machine design temperature is 50 ℃, and be 5 hours drying time.
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102755404A (en) * | 2012-06-26 | 2012-10-31 | 亳州市长生中药饮片有限公司 | Method for decocting Chinese magnoliavine fruit |
| CN102755382A (en) * | 2011-04-28 | 2012-10-31 | 天津天士力之骄药业有限公司 | Method for processing schisandra chinensis |
| CN104523957A (en) * | 2014-12-24 | 2015-04-22 | 北京康仁堂药业有限公司 | Preparation process of vinegar fructus schisandra chinensis |
| CN108653450A (en) * | 2018-06-06 | 2018-10-16 | 吉林省北药药材加工有限公司 | A kind of steamed FRUCTUS SCHISANDRAE with vinegar concocting method |
| CN109045145A (en) * | 2018-09-28 | 2018-12-21 | 安徽汇中州中药饮片有限公司 | Schisandra chinensis process of preparing technique |
| CN109091544A (en) * | 2018-09-28 | 2018-12-28 | 安徽汇中州中药饮片有限公司 | Cortex moutan process of preparing technique |
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- 2009-12-25 CN CN200910264893XA patent/CN101708216B/en not_active Expired - Fee Related
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102755382A (en) * | 2011-04-28 | 2012-10-31 | 天津天士力之骄药业有限公司 | Method for processing schisandra chinensis |
| CN102755382B (en) * | 2011-04-28 | 2016-02-10 | 天津天士力之骄药业有限公司 | A kind of Fructus Schisandrae Chinensis processing method |
| CN102755404A (en) * | 2012-06-26 | 2012-10-31 | 亳州市长生中药饮片有限公司 | Method for decocting Chinese magnoliavine fruit |
| CN104523957A (en) * | 2014-12-24 | 2015-04-22 | 北京康仁堂药业有限公司 | Preparation process of vinegar fructus schisandra chinensis |
| CN108653450A (en) * | 2018-06-06 | 2018-10-16 | 吉林省北药药材加工有限公司 | A kind of steamed FRUCTUS SCHISANDRAE with vinegar concocting method |
| CN109045145A (en) * | 2018-09-28 | 2018-12-21 | 安徽汇中州中药饮片有限公司 | Schisandra chinensis process of preparing technique |
| CN109091544A (en) * | 2018-09-28 | 2018-12-28 | 安徽汇中州中药饮片有限公司 | Cortex moutan process of preparing technique |
| CN116763845A (en) * | 2023-08-03 | 2023-09-19 | 陕西中医药大学 | Preparation method of shizandra berry decoction pieces |
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