CN101703603A - External-use ointment for treating empyrosis and preparation method thereof - Google Patents

External-use ointment for treating empyrosis and preparation method thereof Download PDF

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Publication number
CN101703603A
CN101703603A CN200910227292A CN200910227292A CN101703603A CN 101703603 A CN101703603 A CN 101703603A CN 200910227292 A CN200910227292 A CN 200910227292A CN 200910227292 A CN200910227292 A CN 200910227292A CN 101703603 A CN101703603 A CN 101703603A
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parts
processed
burn
ointment
myrrha
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CN101703603B (en
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朱广波
王留琴
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Abstract

The invention provides external-use ointment for treating empyrosis and a preparation method thereof. The external-use ointment is empyrosis humectation ointment prepared from Chinese medicaments and Western medicaments through processing, and comprises the following components in part by weight: 10 to 30 parts of Chinese angelica, 10 to 25 parts of golden thread, 10 to 25 parts of amur corktree bark, 10 to 25 parts of baical skullcap root, 10 to 20 parts of prepared frankincense, 20 to 25 parts of prepared myrrh, 1 to 3 parts of musk, 10 to 20 parts of borneol, 150 to 270 parts of silver sulfadiazine powder, 500 to 1,000 parts of Vaseline and 40 to 80 parts of bees wax. The ointment adopts the Chinese angelica, the frankincense and the myrrh which have the effects of activating blood circulation, relieving pain and promoting tissue regeneration; the golden thread, the amur corktree bark and the baical skullcap root have the effects of clearing away heat and toxic materials and eliminating dampness; the borneol has bitter and cold properties, can clear away heat to be cool when in external use, and has the lasting effect of constringency, tissue regeneration and odynolysis when being compatible with the musk; and the silver sulfadiazine powder has the effects of sterilization and antiphlogosis. The whole medicament has the effects of promoting blood circulation by removing blood stasis, diminishing inflammation and relieving pain, changing rot and promoting tissue, inhibiting exudation and promoting wound healing, and has low incidence rate of scar.

Description

Externally-applied ointment of treatment burn and preparation method thereof
Technical field:
The present invention relates to a kind of external-applied ointment for the treatment of burn, belong to the medical external medicine, particularly a kind of externally-applied ointment for the treatment of burn and preparation method thereof, it is the moistening ointment of burn that Chinese medicine and Western medicine are made through processing.
Background technology:
At present, Chinese medicine and western medicine kind and Therapeutic Method are more adopting aspect the treatment burn, treatment for large tracts of land I °-III ° burn, dry therapy, exposure method, infrared ray radiation treatment, tincture treatment etc. are arranged, these methods exist anti-infection ability poor, and the course of treatment is long, and misery is arranged, the remained scar ratio height has certain shortcomings such as influence to wound healing.Burn is a common multiple disease in the life, in order to treat burn, adopt of doctor trained in Western medicine is provided with aseptic ward more, or treat with means such as a large amount of antibiotics, on function, also do not reach fully prevent, control and kill harmful antibacterial so that fire victim's wound surface skin and integumentary musculature histogenic immunity power are low.But, also do not possess its condition for the rural area and the remote mountain areas of shortage of medical services and medicines.
Summary of the invention:
The objective of the invention is at above problem, and a kind of externally-applied ointment for the treatment of burn of development and preparation method thereof, this ointment can not only improve anti-infection ability, and pain relieving is fast, suppresses to ooze out, the friction of prevention wound surface, healing is fast, and the cicatrix incidence rate is low.
Technical scheme of the present invention is achieved in that
A kind of externally-applied ointment for the treatment of burn, it is that preparation of raw material by the following weight component forms:
Radix Angelicae Sinensis 10-30 part, Rhizoma Coptidis 10-25 part, Cortex Phellodendri 10-25 part, Radix Scutellariae 10-25 part, Olibanum (processed) 10-20 part, Myrrha (processed) 20-25 part, Moschus 1-3 part, Borneolum Syntheticum 10-20 part, sulfadiazine argentum powder 150-270 part, vaseline 500-1000 part, Cera Flava 40-80 part.
Technical scheme of the present invention can be achieved in that
A kind of externally-applied ointment for the treatment of burn, it is that preparation of raw material by the following weight component forms:
Radix Angelicae Sinensis 10-20 part, Rhizoma Coptidis 10-15 part, Cortex Phellodendri 10-15 part, Radix Scutellariae 10-15 part, Olibanum (processed) 15-20 part, Myrrha (processed) 15-20 part, Moschus 1-2 part, Borneolum Syntheticum 10-20 part, sulfadiazine argentum powder 150-250 part, vaseline 500-800 part, Cera Flava 40-70 part.
Technical scheme of the present invention can also be achieved in that
A kind of externally-applied ointment that is used for the treatment of burn, it is that preparation of raw material by the following weight component forms:
15 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Coptidis, 15 parts of Cortex Phellodendris, 15 parts of Radix Scutellariaes, 15 parts of Olibanum (processed)s, 20 parts of Myrrha (processed)s, 1.3 parts in Moschus, 15 parts of Borneolum Syntheticums, 150 parts in sulfadiazine argentum powder, 800 parts in vaseline, 50 parts in Cera Flava.
Technical scheme of the present invention can also be achieved in that
A kind of preparation method for the treatment of the externally-applied ointment of burn, it is made by following steps:
Radix Angelicae Sinensis 10-30 part, Rhizoma Coptidis 10-25 part, Cortex Phellodendri 10-25 part, Radix Scutellariae 10-25 part, Olibanum (processed) 10-20 part, Myrrha (processed) 20-25 part, Moschus 1-3 part, Borneolum Syntheticum 10-20 part, sulfadiazine argentum powder 150-270 part, vaseline 500-1000 part, Cera Flava 40-80 part.
One, with Radix Angelicae Sinensis 10-30 part, Rhizoma Coptidis 10-25 part, Cortex Phellodendri 10-25 part, Radix Scutellariae 10-25 part, Olibanum (processed) 10-20 part, Myrrha (processed) 20-25 part, Moschus 1-3 part, Borneolum Syntheticum 10-20 part pulverize separately to 120 order fine powder, stand-by;
Two, Cera Flava 40-80 part heating is dissolved when temperature is 30 ℃-40 ℃, add 120 order fine powders of first step processing, Borneolum Syntheticum, Moschus, Olibanum (processed), Myrrha (processed) stir then, are made as the A material, and be stand-by;
Three, the vaseline heating is dissolved, when temperature drops to 100 ℃, the 120 order fine powders that add first step processing, Radix Angelicae Sinensis, Rhizoma Coptidis, Cortex Phellodendri, Radix Scutellariae, stir, when temperature was reduced to 30 ℃-40 ℃, the A material that adds sulfadiazine argentum powder and the processing of second step again continued to stir, after stirring, be the externally-applied ointment that is used for the treatment of burn.
Therapeutic Method of the present invention is: after the wound surface debridement, this ointment evenly is coated on the aseptic husky cloth, and the wrapping wound surface, the next day, change dressings once.Still adopt skin grafting surgery for large tracts of land III ° burn.
The pharmacology of Chinese medicine of the present invention is according to being:
Radix Angelicae Sinensis: nature and flavor are sweet, hot, temperature.Go into the heart, liver, spleen channel.Function: enrich blood and invigorate blood circulation.Menstruction regulating and pain relieving is moisturized laxation.Yong Yu mass in the abdomen knot is poly-, metrorrhagia; Dizziness due to deficiency of blood, diseases such as dryness of the intestine dyschezia.
Rhizoma Coptidis: the nature and flavor hardship, cold.Go into the heart, liver, stomach, large intestine channel.Function: pathogenic fire purging, dampness, detoxifcation, antiinflammatory.
Cortex Phellodendri: nature and flavor suffering, sweet.Go into the heart, spleen, kidney channel.Function: have heat clearing and damp drying, pathogenic fire purging, the effect of skin ulcer, sore swollen toxin is treated in detoxifcation.
Radix Scutellariae: the nature and flavor hardship, cold.Go into spleen, gallbladder, lung meridian.Cure mainly heat clearing and damp drying, pathogenic fire purging, detoxifcation, antiinflammatory.
Olibanum (processed): nature and flavor suffering, hardship, temperature.Go into the heart, liver, spleen channel.Regulating qi and activating blood, analgesic therapy chases after poison, detumescence and promoting granulation.
Myrrha (processed): the nature and flavor hardship, flat.Go into the heart, liver, spleen, kidney channel.Effect: promoting blood circulation and stopping pain, detumescence and promoting granulation, skin infection festers, and getting Myrrha (processed) is to take out when frying to surface-brightening with slow fire, has no side effect.
Moschus: nature and flavor suffering, temperature.Go into the heart, spleen, Liver Channel.Function: have one's ideas straightened out, ward off dirty, collateral dredging, dissipating blood stasis.
Borneolum Syntheticum: nature and flavor suffering, hardship, cold.Go into the heart, lung meridian.Function: logical all keys, the dissipating blood stasis fire, removing nebula makes eye bright, diseases such as reducing swelling and alleviating pain.
Its pharmacological action is: the present invention adopts Radix Angelicae Sinensis, Olibanum, Myrrha, have invigorate blood circulation, pain relieving, promoting muscle growth functions, Rhizoma Coptidis, Cortex Phellodendri, Radix Scutellariae have heat-clearing and toxic substances removing, dampness effect, Borneolum Syntheticum bitter cold, the external heat clearing away is nice and cool, and is lasting with the convergence of Moschus compatibility, granulation promoting, analgesic effect.Sulfadiazine argentum powder has the bactericidal antiphlogistic effect, and whole medicine has blood circulation promoting and blood stasis dispelling, anti-inflammatory analgetic, removing the necrotic tissue and promoting granulation, suppresses to ooze out, and promotes wound healing.
Good effect of the present invention is:
1, the prescription of this product and preparation technology are simple, and the patent medicine cost is low, are applicable to that rural area, mountain area shortage of medical services and medicines crowd use.The present invention has good effect, and instant effect is easy to use, the characteristics of compatibility safety non-toxic.
2, the present invention is isolated from the outside wound surface with this burn ointment by clinical observation, the protection wound surface, and it is fast to have an analgesic effect; antibacterial ability is strong, oozes out to lack, and edema extinction is fast, short treating period; more do not stay the scar pain after, and easy to use, have no side effect the characteristics that cure rate is high.In 200 routine fire victims' treatment, male's 64 examples, women's 85 examples, children's's 51 examples, the age is between between 1-70 year, and 35 years old mean age, the course of disease is from 7 days-45 days, shallow II ° of blister type 120 examples, dark II ° of erosive type 60 examples, III ° of leather type 20 examples.
Its curative effect sees the following form:
The burn typing The example number Effectively Cure Cure rate
Shallow II ° ??120 ??5 ??115 ??96%
The burn typing The example number Effectively Cure Cure rate
Dark II ° ??60 ??3 ??57 ??95%
??III° ??20 ??5 ??15 ??95%
Add up to ??200 ??13 ??187 ??93%
The specific embodiment:
The present invention is described in further detail below in conjunction with embodiment:
Embodiment one:
A kind of externally-applied ointment for the treatment of burn, it is that preparation of raw material by the following weight component forms:
Radix Angelicae Sinensis 15g, Rhizoma Coptidis 10g, Cortex Phellodendri 15g, Radix Scutellariae 15g, Olibanum (processed) 15g, Myrrha (processed) 20g, Moschus 1.3g, Borneolum Syntheticum 15g, sulfadiazine argentum powder 150g, vaseline 800g, Cera Flava 50g.
Its preparation method may further comprise the steps:
A kind of preparation method for the treatment of the externally-applied ointment of burn, it is made by following steps:
One, with Radix Angelicae Sinensis 15g, Rhizoma Coptidis 10g, Cortex Phellodendri 15g, Radix Scutellariae 15g, Olibanum (processed) 15g, Myrrha (processed) 20g, Moschus 1.3g, Borneolum Syntheticum 15g pulverize separately to 120 order fine powder, stand-by;
Two, Cera Flava 50g heating is dissolved when temperature is 30 ℃-40 ℃, add 120 order fine powders of first step processing, Borneolum Syntheticum 15g, Moschus 1.3g, Olibanum (processed) 15g, Myrrha (processed) 20g stir then, are made as the A material, and be stand-by;
Three, vaseline 800g heating is dissolved, when temperature drops to 100 ℃, the 120 order fine powders that add first step processing, Radix Angelicae Sinensis 15g, Rhizoma Coptidis 10g, Cortex Phellodendri 15g, Radix Scutellariae 15g stir then, when temperature is reduced to 30 ℃-40 ℃, the A material that adds sulfadiazine argentum powder 150g and the processing of second step again, continue to stir, after stirring, be the externally-applied ointment that is used for the treatment of burn.
Embodiment two:
A kind of externally-applied ointment that is used for the treatment of burn, it is that preparation of raw material by the following weight component forms:
Radix Angelicae Sinensis 20g, Rhizoma Coptidis 20g, Cortex Phellodendri 20g, Radix Scutellariae 20g, Olibanum (processed) 20g, Myrrha (processed) 20g, Moschus 2g, Borneolum Syntheticum 20g, sulfadiazine argentum powder 200g, vaseline 1000g, Cera Flava 70g.
Its preparation method may further comprise the steps:
A kind of preparation method for the treatment of the externally-applied ointment of burn, it is made by following steps:
One, with Radix Angelicae Sinensis 20g, Rhizoma Coptidis 20g, Cortex Phellodendri 20g, Radix Scutellariae 20g, Olibanum (processed) 20g, Myrrha (processed) 20g, Moschus 2g, Borneolum Syntheticum 20g pulverize separately to 120 order fine powder, stand-by;
Two, Cera Flava 70g heating is dissolved when temperature is 30 ℃-40 ℃, add 120 order fine powders of first step processing, Borneolum Syntheticum 20g, Moschus 2g, Olibanum (processed) 20g, Myrrha (processed) 20g stir then, are made as the A material, and be stand-by;
Three, vaseline 1000g heating is dissolved, when temperature drops to 100 ℃, the 120 order fine powders that add first step processing, Radix Angelicae Sinensis 20g, Rhizoma Coptidis 20g, Cortex Phellodendri 20g, Radix Scutellariae 20g stir then, when temperature is reduced to 30 ℃-40 ℃, the A material that adds sulfadiazine argentum powder 200g and the processing of second step again, continue to stir, after stirring, be the externally-applied ointment of treatment burn.
Clinical observation, its result is as follows:
Typical case's case history:
Medical record one:
The patient, Huang Shoufu, man, 54 years old, because of come institute to go to a doctor by fire burn, body was looked into: head and neck, left hand and right upper extremity forearm, hand thumb, forefinger burn in JIUYUE in 2008 21 days, area reaches 15%, is dark II ° of burn, after being in hospital, clean wound surface, with the moistening ointment wrapping of burn wound surface, after 30 minutes, patient's feels pain obviously alleviates, the next day, change dressings once, and wound surface oozes out minimizing.Wound surface liquefaction after seven days, the local necrosis tissue comes off, the cambium convergence.Changed dressings continuously again 10 days, wound healing is left hospital.
Medical record two:
The patient, the Wang comrade-in-arms, the man, 41 years old, scalded women's head-ornaments portion, trunk and two upper limb on May 26th, 2009 by meal, TBS 45%, II ° is 25%, dark II ° reaches 20%.With the moistening ointment wrapping of burn wound surface, the next day, change dressings after the debridement.II ° of burn-healing after one week, the most of slough liquefaction of dark II ° of burn wound comes off, granulation tissue flap coverage after two weeks, recovery from illness is left hospital.
Medical record three:
Infant, Yu Xiaohang, the man, 4 years old, on July 5th, 2009 by the boiled water burn left hand palm, the right hand, right forearm, lower back, two buttocks, both thighs after big portion.I ° of burn accounts for 10%, and dark II ° accounts for 20%, and III ° accounts for 5%, and TBS reaches 35%.With the moistening ointment wrapping of burn wound surface, wrap up after 1 hour after the debridement, infant pain disappears.I ° of burn-healing after five days, dark II ° and the III ° of most of slough liquefaction of wound surface come off.Dark II ° of wound healing after 15 days, III ° of burn wound's periphery has new granulation tissue to form, and is in hospital 25 days, and burn wound all heals.

Claims (4)

1. externally-applied ointment for the treatment of burn, it is that preparation of raw material by the following weight component forms:
Radix Angelicae Sinensis 10-30 part, Rhizoma Coptidis 10-25 part, Cortex Phellodendri 10-25 part, Radix Scutellariae 10-25 part, Olibanum (processed) 10-20 part, Myrrha (processed) 20-25 part, Moschus 1-3 part, Borneolum Syntheticum 10-20 part, sulfadiazine argentum powder 150-270 part, vaseline 500-1000 part, Cera Flava 40-80 part.
2. the externally-applied ointment of treatment according to claim 1 burn is characterized in that: it is that preparation of raw material by the following weight component forms:
Radix Angelicae Sinensis 10-20 part, Rhizoma Coptidis 10-15 part, Cortex Phellodendri 10-15 part, Radix Scutellariae 10-15 part, Olibanum (processed) 15-20 part, Myrrha (processed) 15-20 part, Moschus 1-2 part, Borneolum Syntheticum 10-20 part, sulfadiazine argentum powder 150-250 part, vaseline 500-800 part, Cera Flava 40-70 part.
3. the externally-applied ointment of treatment according to claim 1 burn is characterized in that: it is that preparation of raw material by the following weight component forms:
15 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Coptidis, 15 parts of Cortex Phellodendris, 15 parts of Radix Scutellariaes, 15 parts of Olibanum (processed)s, 20 parts of Myrrha (processed)s, 1.3 parts in Moschus, 15 parts of Borneolum Syntheticums, 150 parts in sulfadiazine argentum powder, 800 parts in vaseline, 50 parts in Cera Flava.
4. method for preparing the externally-applied ointment of each described treatment burn of claim 1 to 3, it is characterized in that: it may further comprise the steps:
One, with Radix Angelicae Sinensis 10-30 part, Rhizoma Coptidis 10-25 part, Cortex Phellodendri 10-25 part, Radix Scutellariae 10-25 part, Olibanum (processed) 10-20 part, Myrrha (processed) 20-25 part, Moschus 1-3 part, Borneolum Syntheticum 10-20 part pulverize separately to 120 order fine powder, stand-by;
Two, Cera Flava 40-80 part heating is dissolved when temperature is 30 ℃-40 ℃, add 120 order fine powders of first step processing, Borneolum Syntheticum, Moschus, Olibanum (processed), Myrrha (processed) stir then, are made as the A material, and be stand-by;
Three, the heating of vaseline 500-1000 part is dissolved, when temperature drops to 100 ℃, the 120 order fine powders that add first step processing, Radix Angelicae Sinensis, Rhizoma Coptidis, Cortex Phellodendri, Radix Scutellariae, stir then, when temperature was reduced to 30 ℃-40 ℃, the A material that adds sulfadiazine argentum powder 150-270 part and the processing of second step again continued to stir, after stirring, be the externally-applied ointment that is used for the treatment of burn.
CN2009102272921A 2009-12-04 2009-12-04 External-use ointment for treating empyrosis and preparation method thereof Expired - Fee Related CN101703603B (en)

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102940715A (en) * 2012-10-30 2013-02-27 广西梧州三鹤药业有限公司 Pseudo-ginseng ointment and preparation method thereof
CN103083445A (en) * 2011-10-31 2013-05-08 上海中医药大学附属龙华医院 Traditional Chinese medicine preparation used for treating skin ulcers, and preparation method thereof
CN105147881A (en) * 2015-10-28 2015-12-16 李琳 Compound menthol balm for treating burns
CN105708977A (en) * 2016-04-17 2016-06-29 王栋 Traditional Chinese medicine ointment for treating burns and preparation method thereof
CN105749263A (en) * 2016-04-01 2016-07-13 南宁学院 Pharmaceutical composition for treating livestock traumatic skin injuries
CN105853440A (en) * 2015-10-29 2016-08-17 梁秀荣 Scald ointment and preparation method thereof
RU2636227C2 (en) * 2013-01-24 2017-11-21 СЮЙ Кевин Пэн Pharmaceutical composition for thermal injuries and wounds treatment in combination with bone damage
CN107519241A (en) * 2016-06-20 2017-12-29 重庆灵方生物技术有限公司 A kind of medicine liquid for treating burns and scalds
CN107714772A (en) * 2017-11-10 2018-02-23 重庆灵方三帆生物制药有限公司 A kind of medicine liquid for treating burns and scalds and preparation method thereof
CN110680878A (en) * 2018-07-13 2020-01-14 莆田市肤宝生物科技有限公司 Preparation method of ointment for treating burns and scalds

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103083445A (en) * 2011-10-31 2013-05-08 上海中医药大学附属龙华医院 Traditional Chinese medicine preparation used for treating skin ulcers, and preparation method thereof
CN102940715A (en) * 2012-10-30 2013-02-27 广西梧州三鹤药业有限公司 Pseudo-ginseng ointment and preparation method thereof
RU2636227C2 (en) * 2013-01-24 2017-11-21 СЮЙ Кевин Пэн Pharmaceutical composition for thermal injuries and wounds treatment in combination with bone damage
CN105147881A (en) * 2015-10-28 2015-12-16 李琳 Compound menthol balm for treating burns
CN105853440A (en) * 2015-10-29 2016-08-17 梁秀荣 Scald ointment and preparation method thereof
CN105749263A (en) * 2016-04-01 2016-07-13 南宁学院 Pharmaceutical composition for treating livestock traumatic skin injuries
CN105708977A (en) * 2016-04-17 2016-06-29 王栋 Traditional Chinese medicine ointment for treating burns and preparation method thereof
CN107519241A (en) * 2016-06-20 2017-12-29 重庆灵方生物技术有限公司 A kind of medicine liquid for treating burns and scalds
CN107714772A (en) * 2017-11-10 2018-02-23 重庆灵方三帆生物制药有限公司 A kind of medicine liquid for treating burns and scalds and preparation method thereof
CN110680878A (en) * 2018-07-13 2020-01-14 莆田市肤宝生物科技有限公司 Preparation method of ointment for treating burns and scalds

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