CN101690737A - Novel double-solvent fast medicinal-liquor preparation process - Google Patents

Novel double-solvent fast medicinal-liquor preparation process Download PDF

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CN101690737A
CN101690737A CN200710305345A CN200710305345A CN101690737A CN 101690737 A CN101690737 A CN 101690737A CN 200710305345 A CN200710305345 A CN 200710305345A CN 200710305345 A CN200710305345 A CN 200710305345A CN 101690737 A CN101690737 A CN 101690737A
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percolation
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alcohol
extraction
medicinal
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徐吉民
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Abstract

The invention provides a novel double-solvent fast medicinal-liquor preparation process. A conventional method for preparing Chinese medicinal liquor is carried out by use of 35/50 percent liquor or 70 percent alcohol and rice wine in a cold-dip or hot-dip process. The prior process has the problems of too long soaking time, incapability of leaching all active components, not high equipment utilization rate, unsuitability particularly for single-variety industrial mass production, high post-processing cost and difficulty in achieving good taste and strong efficacy. In order to solve the problems, the process adopts a plurality of groups of countercurrent alcohol and a water alternate circulating-heating percolation concentration method. In the later stage of preparation, precipitate obtained after mixing, cooling and standing high-alcohol percolation liquid and low-alcohol percolation liquid is granulated, dried, wrapped in an acid-base dissoluble thin coat, suspended in medicinal liquor and made into the medicinal liquor with strong efficacy and good taste. The novel medicinal-liquor preparation process is used to extract Chinese medicinal components and animal/plant nutritional components, back-distilling, evaporating, concentrating and separating volatile components and water in ethanol. All procedures are channelized to meet GMP requirements. Compared with products sold on the market, the Chinese medicinal liquor can deliver a 25-time effect in solvent in 5-time higher amount, and save heat energy by 45 to 46 percent and condensed water by 70 to 80 percent. The process has the advantages of reducing solvent loss from a range between 25 and 30 percent to less than 5 percent and improving extraction rate by 10 to 15 percent, along with the capability of fully extracting volatile components in alcohol and water.

Description

Novel double-solvent fast medicinal-liquor preparation process
The method for preparing Chinese medicine medicated wine, well-established law be with 35%, 50% Chinese liquor or 70% ethanol and yellow wine in merceration or hot dipping or percolation or refluxing unit with Chinese crude drug in effective ingredient leach, and then through clarification, filtration, seasoning, collude peer processes and make health medicated wine or therapeutic medicated wine.
In old technology, often have: 1, long soaking time, a collection ofly need 5-7 days at least, once need to repeat two weeks, even so, effective ingredient still can not defecation; 2, utilization rate of equipment and installations is not high, especially is not suitable for a large amount of suitability for industrialized production of single variety; 3, post processing-clarification, expense height such as seasoning, difficulty accomplishes that effect is strong, mouthfeel is good again especially; 4, need reclaim the increase expense separately with having remaining wine in steeping in wine bubble, percolation or the preparation medicated wine medicinal residues that reflux.The proposition of this patent is intended to overcome the above problems.
This patent extracts part: 1~8 adverse current dynamic extraction pot connected be combined into one, but allow its become can heat vacuum adverse current dynamically, alcohol, water replaces continuous circulation two-stage and extracts equipment, just can overcome the above problems with this patent equipment and technology.
This patent heating extraction partly is: the ZL99118257X that introduces me extracts double-effect evaporation, knockout drum and the solvent pairs counterflow extraction apparatus received in the cream granulation patent and fuses.When needs heating or need again to reduce cost.When replacing Chinese liquor with edible ethanol, two complete equipments are communicated with the back just can accelerate to extract pharmacy wine speed, reduces the Chinese liquor loss.
Accompanying drawing 1 is a kind of device structure sketch map for preparing the medicated wine new technology: high-order basin I, II are sealing stavings, and its upper and lower end respectively has a valve packing gland, and three apertures are used to into solvent and advance air, and following aperture is used to allow solvent enter each number extraction pot.1~No. 8 extraction pot, its tank body: there is a charging aperture upper end, can pass through flange seal after charging, and also there is an aperture lower end, can take off the blind flange discharging when extracting end-of-job; Have the pipeline aperture in each symmetric position of staving upper and lower, the aperture, lower end can allow gravity tank and the right extraction pot liquid of surveying flow into by pipeline, then high-order basin I, high-order basin II, extraction pot 1~8 replaces circulated in countercurrent integral body by the interconnection successively composition of pipeline valve alcohol, a water.When producing first medicated wine, 8 extraction pot are divided into 1~No. 4,2~No. 5,3~No. 6,4~No. 7,5~No. 8 these five groups, each collects a certain amount of alcohol, if the water percolate is will produce second batch of medicated wine the time, after having proposed discharging, advances in No. 1 jar water second batch of virgin material again, so with No. 6, No. 7, No. 8, form the 6th group No. 1, continue to increase alcohol percolation, other by that analogy, form No. 7, No. 8 No. 1, form the 7th group No. 2, No. 8, No. 1, No. 2, form the 8th group, No. 1 No. 3, No. 2, No. 3, form the 9th group, No. 2 No. 4, No. 3, No. 4, form the tenth group No. 5.When throwing the 3rd batch of medical material, then make No. 3, No. 4, No. 5, No. 6 and form the 11 group ... be the 15 group No. 7, No. 8, No. 1, No. 2, produce the 4th batch and even many batches by that analogy backward.
Contain Chinese crude drug 10% if make, the healthy medicated wine of alcoholic strength 35%, can in 1~No. 8 extraction pot, respectively pack into and pulverize medical material 50kg (moistening 2~4 hours), close all valves, 60% Chinese liquor is injected high-order basin I number, pure water liquid injects basin II number, during the beginning percolation, open the I-1 valve, 11 valves, 21 valves, 31 valves, 42 valves, close 81 valves, 12 valves, 22 valves, 32 valves, 41 valves, allow 60% Chinese liquor among the basin I through No. 1, No. 2, No. 3, No. 4 extraction pot and 42 valves flow in the I A extracting solution storage tank with 12~16ml/min/kg speed, when collecting 400kg, close the I-1 valve, 42 valves, 51 valves are opened the I-2 valve, 41 valves, 52 valves allow 60% Chinese liquor among the basin I through No. 2, No. 3, No. 4, No. 5 extraction pot and 52 valves are in 12~16ml/min/kg velocity flow I A extracting solution storage tank, when collecting 400kg, close the 1-2 valve, 52 valves, 61 valves, open the I-3 valve, 51 valves, 62 valves allow 60% Chinese liquor among the basin I through No. 3, No. 4, No. 5, No. 6 extraction pot and 62 valves are with in 12~16ml/min/kg velocity flow I A extracting solution storage tank, when collecting 400kg, close the I-3 valve, 62 valves, 71 valves, open the I-4 valve, 61 valves, 72 valves allow 60% Chinese liquor among the basin I through No. 4, No. 5, No. 6, No. 7, extraction pot and 72 valves are with in 12~16ml/1min/kg velocity flow IA extracting solution storage tank, when collecting 400kg, close the I-4 valve, 72 valves, 81 valves, open the I-5 valve, 71 valves, 82 valves allow 60% Chinese liquor among the basin I through No. 5, No. 6, No. 7, No. 8 extraction pot and 82 valves, in 12~16ml/mil/kg velocity flow I A extracting solution storage tank, meanwhile, open the II-1 valve, 42 valves, close 12 valves, 22 valves, 32 valves, allow pure water among the high-order basin II through No. 1, No. 2, No. 3, No. 4 extraction pot and 42 valves, flow in the II A extracting solution storage tank with 12~16ml/min/kg speed, collect low pure liquid 400kg after, 5~No. 8 extraction pot at this moment, can collect 60% Chinese liquor percolation 400kg, can allow it flow in the I A storage tank, if only extract a collection of medical material, second group, three groups, four groups, five groups, add pure water percolation method, with reference to 60% Chinese liquor percolation method, each collects 400kg, and the first batch of material medicated wine just announcement is finished.If carry out second batch of production, after first group of No. 1 extraction pot finished water percolation task, at this moment discharging packs behind the new medical material 6,7,8 into, No. 1 jar is formed the 6th group of second batch of medical material, percolation first along with 2,3,4,5,8 each number jars are finished pack into 6,7,8,9,10 groups of percolation of second batch of medical material of discharging behind the water extraction and are just begun continuously.The second batch of virgin material of packing into formed the 6th group of percolation, and method is then to make No. 6, No. 7, No. 8 high alcohol percolation liquid stream go into jar No. 1, and flows into I B basin through 12 valves, collect the 250kg amount after, at this moment just accuse and finish for second group of the 6th group of high alcohol percolation.Then carry out the 7th group of percolation, meanwhile first medicinal residues of No. 2 jars can take out the second batch of virgin material of packing into, form the 7th group, and make No. 7, No. 8, No. 1 percolate flow into No. 2 extraction pot, so start working for the 7th group of second batch, other by that analogy, after ten groups (No. 2, No. 3, No. 4, No. 5) finish low alcohol percolation, then second batch of Production of Medicinal Liqueur finished, and can enter the 3rd batch of medical material percolation.(seeing accompanying drawing 2 Fig. 3)
First 400kg medical material can be collected high pure and mild low each 2000kg of alcohol percolation liquid or more again, this has just guaranteed the pure molten of Chinese crude drug, water-soluble composition just can all propose, soft again in the medicinal residues, only only to produce a collection of medical material, mostly have 16,24 times of high alcohol, low alcohol and even water percolate pass through, minimum No. 1, also there are for No. 88 times of percolation to pass through (as 6,7,8, No. 1 jar repeats once, 16 times pass through just arranged), many in this way continuous production in batches, then each number extraction pot medical material all has 32 times of percolates of 5~9 hours to pass through, and this has just guaranteed the defecation of effective ingredient (seeing Fig. 2 Fig. 3).
Collect two kinds of good percolates, mixed method is: the medicinal liquid that will hang down alcohol is poured in the high pure medicinal liquid slowly, and mix, lower the temperature, leave standstill 24-48h or long again this time after-filtration, filtrate and precipitate are done following processing respectively: filtrate through sugaring etc. collude to after medicated wine, twice of every day be with high-speed stirred 5-10min, promotes medicated wine to coordinate one, quickens fine particles and form aggregate and separate out and avale, so 5-10 days, leave standstill 10-30 days after-filtration again and get product.Precipitate granulation drying is wrapped the insoluble thin clothing of low alcohol and is gone in the wine or incapsulate tablet.
In order to reduce cost again, accelerate effective component extracting speed, can be enabled in double-effect evaporation, knockout drum that I number, II alcohol, the high-order basin fluid of water lower end transverse tube connect.Make high alcohol percolation liquid enter the I evaporator, low alcohol percolation enters the II evaporator.Its concrete operations are: at first start vacuum system, I A2, the I A3 valve of opening I A alcohol extract holding vessel again enter I A basin by extracting solution, after the 5th group of alcohol extract carried, open I A2, I A1 valve by air admission I A basin after, extracting solution only enters the alcohol extract vapo(u)rization system, carry out the heating evaporation fractional distillation, the I B2, the I B3 that meanwhile open I B extracting solution basin allow alcohol extract enter I B basin.Simultaneously first group enter water and carry after, open II A2, II A3 valve, allow the water extract enter II A extracting solution basin, after the 5th group of water is proposed beginning, open II A1, II A2 valve, allow air admission receiver, extracting solution enter water extract heating evaporation, piece-rate system, meanwhile, open II B3, II B2 valve enters II B basin by the water extract.At this moment the water extract separates simultaneously with evaporation and carries out.Its backward each group alcohol, water extraction with evaporation, separate the same operation.Will attention person's alcohol extract evaporation remain on 2/3 of feed liquor amount, the evaporation of aqueous extract remains on 1/4 of feed liquor amount, when if the extraction solvent is not enough, I, the II valve that can open high-order basin just replenish its deficiency by alcohol, the water of gravity tank, carry out continuously to keep percolation, evaporation.
After alcohol, water extraction finish, emit the alcohol extraction concentrated solution,, water extracting liquid poured in the Chinese liquor dissolving tank stirred again, transfer to determining alcohol to 35% with 60% Chinese liquor 1400kg dissolving, content of dispersion 10%, after leave standstill again, spare right, promptly overanxious.The filtering residue processing method has two kinds: the one, after the granulation drying, outsourcing one deck alcohol water is insoluble, and acid subtract can be molten thin clothing, and then quantitatively add in the wine, and allow it be suspended in to take in the wine; The 2nd, dried particles incapsulates or is pressed into tablet and medicated wine is taken.Effective ingredient in the precipitation of removing because of clarification can be remained like this, therefore accomplished that the medicated wine functional component is complete, mouthfeel is good, and function is strong.
Chinese medicine health-care wine is made generally in and contains pure 28-35%.Remove special requirement, just can make and be higher than 40% medicated wine.With being lower than 35% soaking in Chinese liquor, effective ingredient can not all leach in the medical material, and invalid components, composition such as starch, pectin easily leaches, bring difficulty to refinement treatment, and use 60% soaking in Chinese liquor, effective ingredient such as alkaloid, glycoside, anthraquinone analog compound, coumarin and wooden esters, flavone compound, terpene and volatile oil, saponin organic acid etc., which kind of all can soak out no matter exist in the medical material with state, obtain clarifying clear solution, the later stage, refining difficulty was also little, and is highly beneficial to improving the medicated wine effect.
Consider with the low effective ingredient that is dissolved in 50% Chinese liquor and still have and all to propose, and still keep Chinese liquor in the medicinal residues, in order to guarantee that the effective ingredient that is insoluble to low 50% Chinese liquor all can extract, and there is not Chinese liquor in the medicinal residues again, this patent has been got rid of with being lower than medicated liquor behind 30~50% soaking in Chinese liquor and has been added pure water and fall into 35% method, and making leading portion into 60% Chinese liquor or 70% edible ethanol percolation, back segment becomes 50%-0% percolation method with pure water degree of falling.
At present system wine equipment only soaked 5-7 days with an extraction pot, add again after emitting the steeping in wine bubble carried in 3-5 days promptly merge for twice 1,2 soak spare to.This method can not all leach effective ingredient.According to the study, be with the effective ingredient defecation in the medical material, must be with medical material more than 15 times solvent be divided into more than 5 times with methods such as heating or immersion treatment and extract just and might propose effective ingredient is most of.For this reason, this patent has adopted continuous percolation and heating concentration method, removes beginning No. 1, No. 8 with 8 times of solvents with this law, and No. 2, No. 7 other each number all has alcohol, 24 times of percolation of aqueous solvent to extract with outside 16 times of the solvents.As two batches, three batches continuous percolation, then each number jar all has 32 times of alcohol, water percolate to pass through, so effective ingredient can guarantee all to extract.(seeing accompanying drawing 2, Fig. 3, Fig. 4)
Percolation makes the adverse current dynamic percolate into, can avoid guaranteeing constantly more to renew liquid around each medicine grain because of inhomogeneous the causing of charging pressure has crack or obstruction between the medical material powder, promotes the composition dissolving of medical material, diffusion, displacement.
This equipment staving is added with heating jacket outward, when without concentrator, had it can guarantee Various Seasonal can constant temperature production, not can because of season difference make product quality produce difference.
After this equipment seals, vacuum-pumping, air in the medical material is extracted out, allow percolate enter the effective ingredient in the dissolved cell in the crude drug cell body fast, effective ingredient in the cyton constantly is sent in the outer liquid of cell wall, until whole leachings with diffusion, displacement format by the cell cinclides then.

Claims (9)

1. novel double-solvent fast medicinal-liquor preparation process is characterized in that: this technology connects to form one with 8 countercurrent extraction jars and two cover double-effect evaporations, separator.Pulverizing Chinese crude drug is respectively charged into wherein after moistening, again 1~No. 8 extraction pot is formed five percolation groups respectively 1~No. 4,2~No. 5,3~No. 6,4~No. 7,5~No. 8, carry out the adverse current percolation with containing Chinese liquor and the pure water that alcohol is higher than finished product medicated wine respectively then, each group is collected a certain amount of high alcohol, low alcohol percolation liquid, and its two kinds of percolates are mixed, lower the temperature, leave standstill, filter, liquid is through sugaring.Collude, accelerating, storage, refilter the canned medicated wine that gets product.It is insoluble and quantitatively add medicated wine behind the soluble thin clothing of soda acid that the thing that avales after the filtration is wrapped low alcohol through the drying of granulating, or coating and be pressed into tablet not, or incapsulate and quantitatively be attached to outside the bottle, obey in the lump when drinking down, what make like this is the medicated wine that effective ingredient is complete, effect is strong, mouthfeel is good.
2. according to claim 1, novel double-solvent fast medicinal-liquor preparation process, it is characterized in that: when replacing in the Chinese liquor extraction medical material composition with ethanol or needing heating extraction, can start the two cover double-effect evaporations that are connected with high-order basin I, II number drain pipe, alcohol, the water extraction that knockout drum is respectively organized medical material concentrates, it extracts concentrated solution, isolating volatile ingredient, be retained in evaporator, the knockout drum, its ethanol vapour, steam, hot lime set enter respectively separately that system extracts medicinal ingredient again, finish until extraction.After extraction work is finished, emit alcohol, water extraction concentrated solution respectively, pure dope dissolves with 60% Chinese liquor, and the water dope is poured the back that stirs into and adjusted and to contain alcohol to requiring, and it is right to leave standstill, filter, collude.Its filtering residue is handled by claim liquid method.
3. according to claim 1,2 described, novel double-solvent fast medicinal-liquor preparation process is characterized in that: every countercurrent extraction jar, tank body are interlayer, can lead to Steam Heating, thereby have guaranteed Production of Medicinal Liqueur percolation under steady temperature throughout the year.There is a big aperture at every tank body two ends, be used to pass in and out medical material, big up and down aperture can be connected with cover plate by blind flange, the corresponding side in tank body two ends respectively has pipe and leads microstome, pipeline can be passed through in the aperture, lower end, valve is connected with two high-order basins, two cover double-effect evaporations, knockout drum and fluid aperture, another extraction pot upper end, and 8 extraction pot so connect.Just form one and can heat adverse current alcohol, the extraction of water alternate cycles, concentrated, separation system.The countercurrent extraction jar is that rustless steel also can be made by other materials, changeable, quantity can 2 to more than 8, form one group and even a plurality of groups and carry out a kind of, two kinds, three kinds solvent percolation and prepare medicated wine, also can be used for extracting effective one-tenth and the nutritional labeling of plant, animal.Can save solvent, heat energy, condensed water with this equipment, and improve yield.
4. according to claim 1,2 described, novel double-solvent fast medicinal-liquor preparation process is characterized in that: connect to form one with 8 or 6 countercurrent extraction jars, after feeding intake its 1~No. 8 or 1~No. 6 jar are formed 5 groups or 4 groups.To be combined as example: form first group with No. 1, No. 2, No. 3, No. 4 with 8 extraction pot; Form second group No. 2, No. 3, No. 4, No. 5; Form the 3rd group No. 3, No. 4, No. 5, No. 6; Form the 4th group No. 4, No. 5, No. 6, No. 7; Form the 5th group (use six extraction pot in this way, by that analogy, form 4 groups) No. 5, No. 6, No. 7, No. 8.
If only produce a batch medicated wine, promptly when first group collect a certain amount of high alcohol percolation liquid after, stop No. 1 jar work, height alcohol is injected No. 2 jars, so second group No. 2, No. 3, No. 4, No. 5 jar is followed percolation, the 3rd winding and is started working after the high alcohol percolation liquid of collection is a certain amount of, so operation, when starting working for the 5th group, first group can be injected the pure water percolation, after collecting certain low alcohol percolation liquid, with reference to as above method operation, second group, the 3rd group, the 4th group, the 5th group is injected the pure water percolation, when the 5th group of a certain amount of high alcohol of collection, behind the low alcohol percolation liquid, the medicated wine percolation extraction work of first medical material is just accused and is finished.
If carry out second batch of Production of Medicinal Liqueur, then after first first group of No. 1 jar finished with the pure water percolation, finish high alcohol percolation again for the 5th group, take out No. 1 jar medicinal residues this moment and add second batch of virgin material, and make No. 6, No. 7, No. 8 the high alcohol percolation of jar enters jar No. 1, so the 6th group of second batch of medicated wine (No. 6, No. 7, No. 8, No. 1 jar) just begins high alcohol percolation, after first No. 2 jars of second group are intact with the pure water percolation, No. 2 jar medicinal residues of same taking-up, add second batch of virgin material, make No. 7, No. 8, No. 1 high alcohol percolation liquid stream is gone into jar No. 2, so second batch the 7th group begins high alcohol percolation again, other by that analogy, after second batch the 9th group finished high alcohol percolation, the 6th group was injected pure water, collected low alcohol percolation liquid, after the tenth group low alcohol percolation liquid collection was a certain amount of, promptly second batch of medicated wine percolation promptly accused and finished.
If want the 3rd batch of medicated wine of continuous production, finish low alcohol percolation for the 6th group that then works as second batch, when second batch the tenth group finished high alcohol percolation again, the 6th group No. 6 jar Chinese medicine slags can take out, and add the 3rd batch new medical material, and make the high alcohol percolation liquid stream of No. 3, No. 4, No. 5 jars in second batch the tenth group go into jar No. 6, so the 3rd batch the 11st group, promptly No. 3, No. 4, No. 5, No. 6 jar begins high alcohol percolation, by that analogy, and the 3rd batch the 12nd group (No. 4, No. 5, No. 6, No. 7); The 13rd group (No. 5, No. 6, No. 7, No. 8); The 14th group (No. 6, No. 7, No. 8, No. 1); The 15th group of (No. 7, No. 8, No. 1, No. 2) percolation group formed in succession and carried out height alcohol, low alcohol percolation successively, the 15th group finish high alcohol, low alcohol percolation after, the 3rd batch of medicated wine percolation work promptly comes to an end.The 4th batch and even many batches of medicated wine percolation are by that analogy.Such flow process operation has been arranged, just can guarantee the high alcohol of competent time and 24~32 times of medical material amounts, 24~32 times of low alcohol of amount are by medical material, and the effective ingredient in the medical material just can obtain abundant defecation.
5. according to claim 1,2 described, novel double-solvent fast medicinal-liquor preparation process is characterized in that: two cover double-effect evaporation jars are equipped with the spraying separator in its evaporator, its function can fully be separated the gas that is included in the concentrated solution, can prevent also that simultaneously trickle liquid grain from taking away with gas.Two heating tanks of double effect evaporator, interconnection its extracting solution that allows of evaporator enter any tank body, and will evaporate vapour, hot lime set input extraction pot.Its tank body is made with rustless steel or other materials.Its big I is decided as required.
6. according to claim 1,2 described, novel double-solvent fast medicinal-liquor preparation process is characterized in that: its two covers separator can 3~7 layers, or more some more, its function; The I knockout drum can separate volatile ingredient with ethanol, and with alcohol gas, hot lime set input extraction pot; The II separator can be imported alcohol gas high alcohol extraction jar, in steam and the hot lime set input water extraction jar.Its tank body is made with rustless steel or other materials.Its big I is decided as required.
7. according to claim 1,2 described, novel double-solvent fast medicinal-liquor preparation process, it is characterized in that: every countercurrent extraction top ends of cans is added with the valve of vacuum-pumping, when the tank body medical material of packing into, when high pure liquid enters tank body and soaked medical material, shut liquid in-out aperture up and down, the startup vacuum pump, take out air in the crude drug cell, allow liquid enter in the cyton by the cell cinclides.Otherwise, medical material granule center particularly, crude drug cell is under the situation that does not have heating, because the cell cinclides is stopped up by air, percolate can't enter dissolving effective ingredient in the cyton, and effective ingredient just can't replace, diffuse in the outer liquid of medical material granule, even the percolation time is long again by the cell cinclides, many again by solvent, also can't be with effectively composition proposition of institute.
8. according to claim 1,2 described, novel double-solvent fast medicinal-liquor preparation process, it is characterized in that: the mixing of high alcohol, low alcohol percolation liquid is that the low pure medicinal liquid of order is poured in the high pure medicinal liquid slowly, this just can make the effective ingredient coagulation that is partially soluble in low alcohol and is insoluble to high alcohol avale, concentration step-down along with wine, be dissolved in high pure composition and also can fold, add cold preservation, leave standstill and to make the insoluble matter precipitation fully.This method, than using the processed with wine identical with medicated wine concentration to be equipped with medicated wine, post processing more economizes.
9. according to claim 1,2 described, novel double-solvent fast medicinal-liquor preparation process, it is characterized in that: the mixed hypostasis of high alcohol, low alcohol percolation liquid does not abandon, but it is dry to allow it granulate, it is insoluble and devote in the medicated wine behind the soluble thin clothing of soda acid to wrap low alcohol again, or is pressed into tablet or incapsulates and be attached to the outer and wine of bottle and take simultaneously.This just can guarantee that the medicated wine mouthfeel is good with whole effective ingredient clothes down, and function is strong.Had with precipitate incapsulate, tabletting or be suspended in this technology in the wine, when meeting, mouthfeel is adjusted when bad, can make the flavour of a drug of mouthfeel difference wherein propose the effective ingredient of mouthfeel difference earlier with 70% ethanol, (medicinal residues close extraction with other medicated wine again) incapsulates with the mixed precipitate mixing granulation of two wine drying after being condensed into extractum again, and mouthfeel will be got well like this.
CN200710305345A 2007-12-23 2007-12-23 Novel double-solvent fast medicinal-liquor preparation process Pending CN101690737A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103566622A (en) * 2012-07-30 2014-02-12 徐吉民 Novel double/single solvent extraction process equipment
CN105062810A (en) * 2015-07-22 2015-11-18 王荣贵 Saussurea involucrate prepared wine and preparation method thereof
CN112442433A (en) * 2020-12-15 2021-03-05 四川省食品发酵工业研究设计院 Method for blending fruit wine flavoring wine
CN112646684A (en) * 2020-12-15 2021-04-13 四川省食品发酵工业研究设计院 White spirit seasoning wine adding system

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103566622A (en) * 2012-07-30 2014-02-12 徐吉民 Novel double/single solvent extraction process equipment
CN105062810A (en) * 2015-07-22 2015-11-18 王荣贵 Saussurea involucrate prepared wine and preparation method thereof
CN112442433A (en) * 2020-12-15 2021-03-05 四川省食品发酵工业研究设计院 Method for blending fruit wine flavoring wine
CN112646684A (en) * 2020-12-15 2021-04-13 四川省食品发酵工业研究设计院 White spirit seasoning wine adding system

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Application publication date: 20100407