CN101679508B - 基于靶向抗原至抗原呈递细胞上表达的dcir的疫苗 - Google Patents

基于靶向抗原至抗原呈递细胞上表达的dcir的疫苗 Download PDF

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CN101679508B
CN101679508B CN200880011285.1A CN200880011285A CN101679508B CN 101679508 B CN101679508 B CN 101679508B CN 200880011285 A CN200880011285 A CN 200880011285A CN 101679508 B CN101679508 B CN 101679508B
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antigen
dcir
antibody
cells
antigens
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CN101679508A (zh
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G·祖拉夫斯基
J·F·班彻罗
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Baylor Research Institute
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
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    • A61K40/00—Cellular immunotherapy
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    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
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    • A61K47/6891—Pre-targeting systems involving an antibody for targeting specific cells
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    • A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
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    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
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    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
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    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
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CN200880011285.1A 2007-02-02 2008-02-01 基于靶向抗原至抗原呈递细胞上表达的dcir的疫苗 Expired - Fee Related CN101679508B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88803207P 2007-02-02 2007-02-02
US60/888,032 2007-02-02
PCT/US2008/052850 WO2008097866A2 (en) 2007-02-02 2008-02-01 Vaccines based on targeting antigen to dcir expressed an antigen-presenting cells

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CN101679508A CN101679508A (zh) 2010-03-24
CN101679508B true CN101679508B (zh) 2014-11-05

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US (5) US8057798B2 (enExample)
EP (2) EP2115002B1 (enExample)
JP (1) JP5377330B2 (enExample)
KR (1) KR20090114430A (enExample)
CN (1) CN101679508B (enExample)
AU (1) AU2008214032B2 (enExample)
BR (1) BRPI0807160A2 (enExample)
CA (1) CA2715044A1 (enExample)
IL (1) IL200088A0 (enExample)
MX (1) MX2009008140A (enExample)
NZ (2) NZ578696A (enExample)
TW (1) TWI446921B (enExample)
WO (1) WO2008097866A2 (enExample)
ZA (1) ZA200905347B (enExample)

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