CN101669920A - Strong anti-oxidation DHA microcapsule and preparation method thereof - Google Patents

Strong anti-oxidation DHA microcapsule and preparation method thereof Download PDF

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CN101669920A
CN101669920A CN 200810042721 CN200810042721A CN101669920A CN 101669920 A CN101669920 A CN 101669920A CN 200810042721 CN200810042721 CN 200810042721 CN 200810042721 A CN200810042721 A CN 200810042721A CN 101669920 A CN101669920 A CN 101669920A
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dha
microcapsule
antioxidant
according
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CN 200810042721
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俊 唐
杰 张
葛海涛
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阜宁怀仁生物有限公司
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Abstract

The invention relates to a strong anti-oxidation DHA microcapsule. The microcapsule comprises the following components in percentage by weight: 10 to 30 percent of DHA fish oil, 0.02 to 0.2 percent ofantioxidant, 10 to 60 percent of wall material, and 5 to 30 percent of auxiliary wall material 5. The invention also relates to a method for preparing the strong anti-oxidation DHA microcapsule. On the basis of the prior process, the microcapsule is prepared by adding the antioxidant to oil phase and water phase respectively and performing emulsification, high-pressure homogenization, improved spray granulation and cold-air boiling-drying. The newly added antioxidant can produce better anti-oxidation effects and greatly improve the oxidation stability of the DHA microcapsule so as to prolongthe shelf life of products, and the improved spray granulation and the cold-air boiling-drying process can increase the yield of the DHA microcapsule. The DHA microcapsule can be used in the fields ofmedicines, foods, beverages and the like.

Description

一种强抗氧化型DHA微囊及其制备方法 A potent antioxidant DHA microcapsule type and preparation method

技术领域 FIELD

本发明涉及一种制剂及其制备方法,尤其是涉及一种强抗氧化型DHA微囊及其制备方法。 The present invention relates to a method for its preparation, in particular to a strong antioxidant DHA microcapsule type and preparation method.

背景技术 Background technique

DHA (二十二碳六烯酸)是细胞膜、视网膜、大脑的重要脂质成分,对脑神经的形成、维护脑神经的正常机能、延缓脑神经的衰退起着重要的作用;EPA的代谢产物二十碳酸衍生物能有效调节花生四烯酸、前列腺素、白三烯等生物活性物质的合成,从而具有防治心脑血管疾病、炎症、生殖系统的疾患以及增强人体自身免疫的功能等。 DHA (docosahexaenoic acid) is an important component of membrane lipids, retina, brain, brain formation, maintenance of normal brain function, slow decline brain plays an important role; metabolites of EPA twenty carbonic acid derivative can effectively regulate the arachidonic acid, the synthesis of prostaglandins, leukotrienes and other biologically active substances, so as to have prevention and treatment of cardiovascular and cerebrovascular diseases, inflammation and disorders of the reproductive system to enhance the body's own immune function.

但是DHA和EPA非常容易被空气中的氧所氧化,给它们的再加工和保存带来一定的麻烦。 However, DHA and EPA are easily oxidized by oxygen in the air, to their reprocessing and storage bring some trouble. 将DHA鱼油进行微囊技术的包裹,可以极大的增强产品稳定性,延长其产品货架期。 The DHA fish oil microencapsulation technology package, can greatly enhance product stability, prolong the shelf life of products. 现阶段,微囊技术在鱼油制品方面已有一定的应用,例如公开号为CN1927050A的发明专利申请文件提到的DHA鱼油胶囊的制备方法,但是现有技术制得的鱼油微胶囊普遍存在抗氧化性较弱的缺点,使其产品稳定性不是很好,因而限制了它的产品货架期。 Stage, microencapsulation technology has applications in certain fish products, e.g. DHA Publication No. preparing fish oil capsules patent application CN1927050A mentioned invention, but the prior art fish oil microcapsules prepared ubiquitous antioxidant weaker shortcomings, it is not very good product stability, thus limiting its shelf life of products. 同时,现有主要的喷雾干燥技术对于微囊的收率比较难以控制以及导致一些原料的损失造成浪费。 Meanwhile, conventional spray drying techniques main more difficult to control and leads to wasted raw material for some loss of yield of microcapsules.

发明内容 SUMMARY

本发明所要解决的技术问题提供一种强抗氧化型DHA微囊及制备方法,通过将DHA鱼油、抗氧化剂、囊材、乳化剂等共同乳化、均质,喷雾造粒经过冷风沸腾干燥制成强抗氧化型DHA微囊,新配方显著提高微囊的产品稳定性及产率,可直接用于医药、食品、饮料等领域。 The present invention solves the technical problem to provide a strong anti-oxidation type and preparation method of microcapsules DHA, DHA by the fish oil, an antioxidant, a capsule material, emulsifier jointly emulsified, homogenized, spray dried granules are made through the cold boiling DHA strong antioxidant type microcapsules, microcapsules new formula significantly improve product stability and yield, it can be directly used in medicine, food and beverage.

本发明涉及的一种强抗氧化型DHA微囊的组成是:各组分之间的重量百分比是DHA鱼油10%〜30%,抗氧化剂0. 02%〜0. 2%,壁材10%〜60%,辅助壁材5%〜30%。 A potent antioxidant type DHA microcapsule compositions of the present invention is directed to: the weight percent of each component is between 10% ~ 30% DHA Fish Oil, antioxidant 0.02% ~ 0 2%, 10% wall material. ~ 60%, ~ 30% auxiliary wall material 5%. 优选为DHA鱼油20%〜30%,抗氧化剂0. 1%〜0. 2%,壁材30%~60%,辅助壁材10%〜30%。 DHA is preferably 20% ~ 30% fish oil, 0.1% antioxidant ~ 0. 2% wall material 30% to 60%, ~ 30% auxiliary wall material 10%. 本发明上述组分中: In the present invention, the above components:

1、 DHA鱼油中DHA(二十二碳六烯酸)为主要成份,DHA(二十二碳六烯酸)与EPA(二十碳五烯酸的重量百分比含量)比例大于7。 1, DHA fish oil DHA (docosahexaenoic acid) as a main component, DHA (docosahexaenoic acid) ratio (eicosapentaenoic acid content by weight) EPA is greater than 7.

2、 添加到囊材溶液中的抗氧化剂用维生素C、茶多酚的一种或两种。 2, an antioxidant was added to the solution of capsule material with vitamin C, polyphenols one or two.

3、 添加到芯材溶液中的抗氧化剂用维生素E、卵磷脂、丁基羟基茴香醚的一种或两种。 3, an antioxidant is added to the core material with a solution of vitamin E, lecithin, butylated hydroxy anisole or both.

4、 囊材用辛烯基琥珀酸酯淀粉、明胶、阿拉伯胶的一种或2种以上。 4, the balloon timber octenyl succinate starch, gelatin, one or more kinds of gum arabic.

5、 辅助囊材用蔗糖酯、糊精、酪蛋白酸钠的一种或2种以上。 5, the auxiliary bag timber sucrose esters, dextrin, sodium caseinate one kind or two or more kinds. 制备方法 Preparation

1) 、制备油相溶液:将上述DHA鱼油与抗氧化剂按配比混合搅拌均匀。 1), an oil phase solution was prepared: The above DHA ratio of fish oil with an antioxidant by mixing uniformly.

2) 、制备水相溶液:将上述壁材、辅助壁及抗氧化剂按配比混合于水中搅拌分散均匀。 2), the aqueous phase was prepared: The material of the wall, the auxiliary wall and antioxidants mixed according to the ratio in water was stirred evenly dispersed.

3) 、制备乳状液:将油相溶液缓慢加入水相溶液高速搅拌乳化一定时间。 3) to prepare an emulsion: the oil phase was slowly added to the water phase emulsion was stirred at high speed a certain time.

4) 、高压均质:将上述乳状液在40〜50Mpa压力下高压均质3次以上。 4), a high pressure homogenizer: The above emulsion in a high pressure homogenizer 40~50Mpa pressure more than 3 times.

5) 、喷雾造粒:将上述均质后的乳状液加入离心式喷雾干燥机中,进风温度为150〜190°C,出风温度为70〜80'C ,喷头转速为2〜3万转的条件下,进行喷雾造粒。 5), spray granulation: The homogenized emulsion was added after the centrifugal spray drier, inlet air temperature is 150~190 ° C, the air temperature was 70~80'C, the head speed of 2 ~ Wan under the conditions of transfer, spray granulation.

6) 、冷风沸腾干燥:将上述造粒后的微囊在一定温度下进行冷风沸腾干燥,制得强氧化型DHA微囊。 6), cold fluidized drying: after the microcapsules for cold granulation was dried at a temperature of boiling, strongly oxidized DHA prepared microcapsule.

本发明制得的强抗氧化性DHA微囊可广泛应用于医药、食品、饮料等领域作为添加剂。 Prepared by the invention is a strong antioxidant DHA microcapsules can be widely used in medicine, food, beverage or the like as an additive. 由于该发明采用分别在油水相制备溶液中添加抗氧化剂,因此用该方法制得的DHA微囊其产品抗氧化性有显著增强,产品货架期大大延长,同时采用冷风沸腾干燥技术,明显改善了微囊的得率并减少了原材料的浪费。 Since the invention employs an antioxidant were added to the oil phase solution is prepared, so that the microcapsules anti-oxidation products obtained by this method have a significantly enhanced DHA, greatly extend the shelf life of the product, while using cold boiling drying techniques, significantly improved microcapsules yield and reducing the waste of raw materials.

附图说明 BRIEF DESCRIPTION

图1是本发明各个微囊之间的抗氧化性能比较图; FIG 1 is an oxidation resistance comparison between the respective microcapsules;

具体实施方式 detailed description

下面结合附图具体介绍本发明的具体实施方式。 The following detailed description of specific embodiments of the present invention in conjunction with the accompanying drawings. 实施例1DHA鱼油15% Example embodiments 1DHA 15% fish oil

明胶60% Gelatin 60%

维生素C 0. 1% Vitamin C 0. 1%

卵磷脂0. 1% Lecithin 0.1%

糊精24.8% Dextrin 24.8%

纯净水适量制备方法 Preparation Purified Water q.s.

1) 、制备油相溶液:将DHA鱼油与维生素C按配比混合搅拌均匀。 1) preparing an oil phase solution: DHA ratio of fish oil and vitamin C by mixing uniformly.

2) 、制备水相溶液:将明胶、糊精及卵磷脂按配比混合于水中搅拌分散均匀。 2) Preparation of aqueous phase solution: gelatin, dextrin and lecithin mixed according to the ratio in water was stirred evenly dispersed.

3) 、制备乳状液:将油相溶液缓慢加入水相溶液高速搅拌乳化一定时间。 3) to prepare an emulsion: the oil phase was slowly added to the water phase emulsion was stirred at high speed a certain time.

4) 、高压均质:将上述乳状液在40〜50Mpa压力下高压均质3次以上。 4), a high pressure homogenizer: The above emulsion in a high pressure homogenizer 40~50Mpa pressure more than 3 times.

5) 、喷雾造粒:将上述均质后的乳状液加入离心式喷雾干燥机中,进风温度为150〜190°C,出风温度为70〜80。 5), spray granulation: The homogenized emulsion was added after the centrifugal spray drier, inlet air temperature is 150~190 ° C, the air temperature is 70~80. C ,喷头转速为2〜3万的条件下,进行喷雾造粒。 Under C, head speed of 2 to 3 million for the conditions, spray granulation.

6) 、冷风沸腾干燥:将上述造粒后的微囊在一定温度下进行冷风沸腾干燥,制得微 6), cold fluidized drying: after the microcapsules for cold granulation was dried at a temperature boiling, micro prepared

实施例2 Example 2

DHA鱼油 20% DHA fish oil 20%

辛烯基琥珀酸酯淀粉 50% Octenyl succinate starch 50%

维生素c 0. 1% Vitamin c 0. 1%

维生素E 0. 1% Vitamin E 0. 1%

酪蛋白酸钠 29. 8% 29.8% sodium caseinate

纯净水 适量 Purified Water q.s.

制备方法 Preparation

1) 、制备油相溶液:将DHA鱼油与维生素C按配比混合搅拌均匀。 1) preparing an oil phase solution: DHA ratio of fish oil and vitamin C by mixing uniformly.

2) 、制备水相溶液:将辛烯基琥珀酸酯淀粉、酪蛋白酸钠及维生素E按配比混合于 2) prepare an aqueous phase solution: octenyl succinate starch, sodium caseinate and vitamin E mixed according to the ratio

水中搅拌分散均匀。 Stirring uniformly dispersed in water.

3) 、制备乳状液:将油相溶液缓慢加入水相溶液高速搅拌乳化一定时间。 3) to prepare an emulsion: the oil phase was slowly added to the water phase emulsion was stirred at high speed a certain time.

4) 、高压均质:将上述乳状液在40〜50Mpa压力下高压均质3次以上。 4), a high pressure homogenizer: The above emulsion in a high pressure homogenizer 40~50Mpa pressure more than 3 times.

5) 、喷雾造粒:将上述均质后的乳状液加入离心式喷雾干燥机中,进风温度为150〜 5), spray granulation: The homogenized emulsion was added after the centrifugal spray drier, inlet air temperature of 150~

6190°C,出风温度为70〜80°C,喷头转速为2〜3万转的条件下,进行喷雾造粒。 6190 ° C, the air temperature is 70~80 ° C, head speed of 2 to 3 million revolutions under the conditions of spray granulation.

6)、冷风沸腾干燥:将上述造粒后的微囊在一定温度下进行冷风沸腾干燥,制得微囊。 6), cold fluidized drying: after the microcapsules for cold granulation was dried at a temperature and boiling to prepare microcapsules.

实施例3 Example 3

DHA鱼油25% 辛烯基琥珀酸酯淀粉45% 25% DHA Fish Oil octenyl succinate starch 45%

茶多酚0.05% Polyphenols 0.05%

卵磷脂0. 15% Lecithin 0.15%

酪蛋白酸钠29.8% Sodium caseinate 29.8%

纯净水适量制备方法 Preparation Purified Water q.s.

1) 、制备油相溶液:将DHA鱼油与茶多酚按配比混合搅拌均匀。 1) preparing an oil phase solution: DHA ratio of fish oil with polyphenols by mixing uniformly.

2) 、制备水相溶液:将辛烯基琥珀酸酯淀粉、酪蛋白酸钠及卵磷脂按配比混合于水中搅拌分散均匀。 2) prepare an aqueous phase solution: starch octenyl succinate, and sodium caseinate by the mixing ratio of lecithin in water was stirred evenly dispersed.

3) 、制备乳状液:将油相溶液缓慢加入水相溶液高速搅拌乳化一定时间。 3) to prepare an emulsion: the oil phase was slowly added to the water phase emulsion was stirred at high speed a certain time.

4) 、高压均质:将上述乳状液在40〜50Mpa压力下高压均质3次以上。 4), a high pressure homogenizer: The above emulsion in a high pressure homogenizer 40~50Mpa pressure more than 3 times.

5) 、喷雾造粒:将上述均质后的乳状液加入离心式喷雾干燥机中,进风温度为150〜 190°C,出风温度为70〜80°C,喷头转速为2〜3万转的条件下,进行喷雾造粒。 5), spray granulation: The homogenized emulsion was added after the centrifugal spray drier, inlet air temperature of 150~ 190 ° C, the air temperature is 70~80 ° C, head speed of 2 ~ Wan under the conditions of transfer, spray granulation.

6) 、冷风沸腾干燥:将上述造粒后的微囊在一定温度下进行冷风沸腾干燥,制得微囊。 6), cold fluidized drying: after the microcapsules for cold granulation was dried at a temperature and boiling to prepare microcapsules.

实施例4 Example 4

DHA鱼油25% DHA fish oil 25%

明胶40% Gelatin 40%

茶多酚0.05% Polyphenols 0.05%

卵磷脂0.05% Lecithin 0.05%

蔗糖酯34.9% 纯净水适量制备方法1) 、制备油相溶液:将DHA鱼油与茶多酚按配比混合搅拌均匀。 Sucrose esters 34.9% Water qs purified preparation method 1), preparing an oil phase solution: DHA ratio of fish oil with polyphenols by mixing uniformly.

2) 、制备水相溶液:将明胶、蔗糖酯及卵磷脂按配比混合于水中搅拌分散均匀。 2) prepare an aqueous phase solution: gelatin, sucrose esters and lecithin in water was stirred by the mixing ratio dispersed.

3) 、制备乳状液:将油相溶液缓慢加入水相溶液高速搅拌乳化一定时间。 3) to prepare an emulsion: the oil phase was slowly added to the water phase emulsion was stirred at high speed a certain time.

4) 、高压均质:将上述乳状液在40〜50Mpa压力下高压均质3次以上。 4), a high pressure homogenizer: The above emulsion in a high pressure homogenizer 40~50Mpa pressure more than 3 times.

5) 、喷雾造粒:将上述均质后的乳状液加入离心式喷雾干燥机中,进风温度为150〜 19(TC,出风温度为70〜80°C,喷头转速为2〜3万转的条件下,进行喷雾造粒。 5), spray granulation: The homogenized emulsion was added after the centrifugal spray drier, inlet air temperature of 150~ 19 (TC, the air temperature is 70~80 ° C, head speed of 2 ~ Wan under the conditions of transfer, spray granulation.

6) 、冷风沸腾干燥:将上述造粒后的微囊在一定温度下进行冷风沸腾干燥,制得微 6), cold fluidized drying: after the microcapsules for cold granulation was dried at a temperature boiling, micro prepared

实施例5 Example 5

DHA鱼油30% DHA fish oil 30%

阿拉伯胶50% Gum Arabic 50%

茶多酚0.05% Polyphenols 0.05%

维生素E 0. 15% Vitamin E 0. 15%

糊精29.9% Dextrin 29.9%

纯净水适量制备方法 Preparation Purified Water q.s.

1) 、制备油相溶液:将DHA鱼油与茶多酚按配比混合搅拌均匀。 1) preparing an oil phase solution: DHA ratio of fish oil with polyphenols by mixing uniformly.

2) 、制备水相溶液:将阿拉伯胶、糊精及维生素E按配比混合于水中搅拌分散均匀。 2) prepare an aqueous phase solution: gum arabic, dextrin and vitamin E mixed according to the ratio in water was stirred evenly dispersed.

3) 、制备乳状液:将油相溶液缓慢加入水相溶液高速搅拌乳化一定时间。 3) to prepare an emulsion: the oil phase was slowly added to the water phase emulsion was stirred at high speed a certain time.

4) 、高压均质:将上述乳状液在40〜50Mpa压力下高压均质3次以上。 4), a high pressure homogenizer: The above emulsion in a high pressure homogenizer 40~50Mpa pressure more than 3 times.

5) 、喷雾造粒:将上述均质后的乳状液加入离心式喷雾干燥机中,进风温度为150〜 19(TC,出风温度为70〜80。C,喷头转速为2〜3万转的条件下,进行喷雾造粒。 5), spray granulation: The homogenized emulsion was added after the centrifugal spray drier, inlet air temperature of 150~ 19 (TC, the air temperature was 70~80.C, the head speed of 2 ~ Wan under the conditions of transfer, spray granulation.

6) 、冷风沸腾干燥:将上述造粒后的微囊在一定温度下进行冷风沸腾干燥,制得微囊。 6), cold fluidized drying: after the microcapsules for cold granulation was dried at a temperature and boiling to prepare microcapsules.

实验结果 Experimental results

<table>table see original document page 8</column></row> <table><table>table see original document page 9</column></row> <table> <Table> table see original document page 8 </ column> </ row> <table> <table> table see original document page 9 </ column> </ row> <table>

含量稳定性及抗氧化性实验 Content of stability and oxidation resistance experiment

1、将实施例1、 2、 3、 4、 5制备所得的强抗氧化型DHA微囊与普通DHA微囊放置于加速试验箱中,温度6(TC,湿度为75%贮存10天,分别于第5、 IO天考察产品DHA 含量的变化情况。<table>table see original document page 9</column></row> <table>从表格中可以看出本发明制备技术下制得的微囊含量稳定性明显高于普通微囊,充分说明了发明技术的优越性。 1, Example 1, 2, 3, 4, 5 obtained in Preparation strong antioxidant and ordinary type microcapsules DHA DHA microcapsules placed in the acceleration chamber, the temperature of 6 (TC, humidity of 75% Storage 10 days, respectively, on the first 5 days of the change of product inspection DHA content of IO. <table> table see original document page 9 </ column> </ row> <table> As can be seen from the table, the preparation techniques of the present invention in microcapsules prepared stability of the content of the microcapsules was significantly higher than normal, which shows technical superiority of the present invention.

2、将实施例l、 2、 3、 4、 5制备所得的强抗氧化型DHA微囊与普通DHA微囊放置于加速试验箱中,温度45。 2, Example l, 2, 3, 4, 5 obtained in Preparation strong antioxidant and ordinary type microcapsules DHA DHA microcapsules placed in the acceleration chamber, and a temperature of 45. C,湿度为30%贮存30天,分别于第5、 10、 15、 20、 30天考察产品过氧化值的变化情况。 C, humidity of 30% Storage 30 days, respectively, the changes of 5, 10, 15, 20, 30 days investigated products peroxide value. (结果附图l) (Results BRIEF l)

由图可见,在加速实验条件下普通微囊过氧化值的升高速率明显高于本发明制备的微囊过氧化值的升高速率,可知本发明明显提高了DHA鱼油微囊抗氧化性能。 Seen from the figure, Common microcapsule peroxide value under accelerated test conditions of elevated significantly higher than the rate of the microcapsules prepared in the present invention, the rate of increase in peroxide value, it is understood the present invention significantly improves the oxidation resistance of DHA fish oil microcapsules.

以上虽然结合具体实施例详细阐述了本发明,但所述具体实施例只是举例说明,而非用于限定本的内容和范围。 Although the above embodiments described in detail with reference to specific embodiments of the present invention, but the specific examples are merely illustrative, and not intended to limit the scope of the present content.

本发明的保护范围应以权利要求书的记载为准。 The scope of the invention should be described in the claims shall prevail. 根据本发明的附图和详细描述,对熟悉本技术领域的技术人员来说显而易见的各种变化和修改也在本发明权利要求的精神和范围内。 The drawings and detailed description of the present invention, a skilled in the art would be apparent to the art that various changes and modifications are within the spirit and scope of the claimed invention.

Claims (9)

  1. 1、一种强抗氧化型DHA微胶囊,其特征是:各组分之间的重量百分比是:DHA鱼油10%~30%,抗氧化剂0.02%~0.2%,壁材10%~60%,辅助壁材5%~30%。 1, a potent antioxidant DHA microcapsule type, characterized in that: the percentage by weight is between the components: DHA 10% to 30% fish oil, antioxidant 0.02% to 0.2%, the wall material 10% to 60%, auxiliary wall material 5% to 30%.
  2. 2、 根据权利要求1所述的一种强抗氧化型DHA微囊,其特征是:各组分之间的重量百分比是:DHA鱼油20%〜30%,抗氧化剂0. 1%〜0. 2%,壁材30%〜60%,辅助壁材10%〜30%。 2, according to one type strong antioxidant DHA microcapsule according to claim 1, wherein: the percentage by weight is between the components: DHA 20% ~ 30% fish oil, 0.1% antioxidant ~ 0. 2%, 30% ~ 60% wall material, auxiliary wall material 10% ~ 30%.
  3. 3、 根据权利要求1或2所述的一种强抗氧化型DHA微囊,其特征是:DHA鱼油中DHA(二十二碳六烯酸)为主要成份,DHA(二十二碳六烯酸)与EPA(二十碳五烯酸的重量百分比含量)比例大于7。 3, according to one type strong antioxidant DHA microcapsule of claim 1 or claim 2, wherein: fish oil DHA DHA (docosahexaenoic acid) as a main component, DHA (docosahexaenoic ene acid) and EPA (eicosapentaenoic acid content by weight) ratio of more than 7.
  4. 4、 根据权利要求1或2所述的一种强抗氧化型DHA微囊,其特征是:抗氧化剂为维生素C、维生素E、茶多酚、卵磷脂、丁基羟基茴香醚的一种或2种以上。 4, according to one type strong antioxidant DHA microcapsule of claim 1 or claim 2, wherein: the antioxidant is vitamin C, vitamin E, polyphenols, lecithin, or butylhydroxyanisole two or more kinds.
  5. 5、 根据权利要求1或2所述的一种强抗氧化型DHA微囊,其特征是:壁材为辛烯基琥珀酸酯淀粉、明胶、阿拉伯胶的一种或2种以上。 5, according to claim DHA a potent antioxidant microcapsule type or claim 12, wherein: the wall material is octenyl succinate starch, gelatin, gum arabic one kind or two or more kinds.
  6. 6、 根据权利要求1或2所述的一种强抗氧化型DHA微囊,其特征是:辅助壁材为蔗糖酯、糊精、酪蛋白酸钠的一种或2种以上。 6. A strong antioxidant type DHA microcapsule of claim 1 or claim 2, characterized in that: auxiliary wall material is a sucrose ester, dextrin, sodium caseinate one kind or two or more kinds.
  7. 7、 一种制备如权利要求1或2任一所述的一种强抗氧化型DHA微囊制备工艺方法,其步骤为:1) 、将所述的DHA鱼油与抗氧化剂按配比混合搅拌均匀制备所得油相溶液;2) 、将所述的壁材、辅助壁材及抗氧化剂按配比混合于水中搅拌分散均匀制备所得水相溶液;3) 、然后将所述的油相溶液缓慢加入所述的水相溶液高速搅拌乳化一定时间后制备所得乳状液;4) 、再将所述的乳状液在40〜50Mpa压力下高压均质3次以上得到高压均质;5) 、所述的均质后的乳状液加入离心式喷雾干燥机中进行喷雾造粒,制备成微囊,反应条件为:进风温度为150〜190°C,出风温度为70〜80°C,喷头转速为2〜3万转;6) 、最后将所述的喷雾造粒后的微囊在一定温度下进行冷风沸腾干燥,制得强抗氧化型DHA微囊。 7. A process for preparing a potent antioxidant as claimed in type a process for preparing DHA according to claim 1 or any of microcapsules 2, comprises the following steps: 1), the DHA in fish oil with an antioxidant by uniformly mixing ratio the resulting oil phase solution was prepared; 2), the wall material, wall material and the secondary antioxidant according to the mixing ratio of water and dispersed by stirring the resulting homogeneous solution was prepared in the aqueous phase; 3), and then the oil phase was slowly added to the solution of the said aqueous phase solution stirred speed emulsion preparation emulsified in a predetermined time; 4), then the emulsion a high pressure homogenizer three times or more to obtain high-pressure homogenizer at a pressure 40~50Mpa; 5), the average after the emulsion was added a centrifugal spray dryer quality spray granulation to prepare a microcapsule, the reaction conditions were: inlet air temperature of 150~190 ° C, the air temperature is 70~80 ° C, the rotational speed of the nozzle 2 ~ 3 million transfer; 6), and finally the microcapsules after the spray granulation is carried out at a temperature of boiling cold air dried to obtain microcapsules DHA strong antioxidant type.
  8. 8、 根据权利要求7所述的一种强抗氧化型DHA微囊的制备工艺方法,其特征是:在微囊化工艺中,采用分别在油相、水相中添加不同的抗氧化剂进行乳化制备技术。 8. A method of preparation according to claim strong antioxidant type DHA microcapsule according to claim 7, characterized in that: in the microencapsulation process, respectively using the aqueous phase, adding different antioxidants is emulsified in the oil preparation techniques.
  9. 9、根据权利要求7所述的一种强抗氧化型DHA微囊的制备工艺方法,其特征是:将喷雾造粒后的微囊在70〜9(TC下进行冷风沸腾干燥。 9. A method of preparation according to claim strong antioxidant type DHA microcapsule according to claim 7, characterized in that: the microcapsules for cold spray granulation boiling dried (under 70~9 TC.
CN 200810042721 2008-09-10 2008-09-10 Strong anti-oxidation DHA microcapsule and preparation method thereof CN101669920A (en)

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