CN101019838A - Linseed oil microcapsule powder and its prepn - Google Patents

Linseed oil microcapsule powder and its prepn Download PDF

Info

Publication number
CN101019838A
CN101019838A CN 200710063829 CN200710063829A CN101019838A CN 101019838 A CN101019838 A CN 101019838A CN 200710063829 CN200710063829 CN 200710063829 CN 200710063829 A CN200710063829 A CN 200710063829A CN 101019838 A CN101019838 A CN 101019838A
Authority
CN
Grant status
Application
Patent type
Prior art keywords
linseed oil
microcapsule powder
weight
emulsion
linseed
Prior art date
Application number
CN 200710063829
Other languages
Chinese (zh)
Other versions
CN100506282C (en )
Inventor
段明星
周华锋
郑昌学
陈斌
Original Assignee
清华大学
江苏隆力奇生物科技股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Abstract

The present invention is linseed oil microcapsule powder and its preparation, and features that modified polysaccharide, sodium octyl alkenyl succinate starch, is used as capsule wall material for forming microcapsule in preparing linseed oil microcapsule powder. The preparation process includes adding linseed oil into the solution of sodium octyl alkenyl succinate starch, stirring to form homogeneous emulsion, high pressure homogenizing to obtain linseed oil emulsion of granularity smaller than 1000 nm, and final spray drying or freeze drying to obtain white linseed oil microcapsule powder with high stability and high flowability. The linseed oil microcapsule powder has high linseed oil activity, high stability and high bioavailability, and may be applied in food and health product.

Description

亚麻油微胶囊粉末及其制备方法 Linseed microcapsule powder and its preparation method

技术领域 FIELD

本发明涉食品及保健品领域,具体涉及亚麻油微胶囊粉末及其制备方法。 The present invention relates to the field of food and health products, particularly relates to linseed oil microcapsule powder and its preparation method.

背景技术 Background technique

亚麻油主要是由胡麻压榨而来,胡麻主要分布在华北和西北地区,由胡麻压榨制得的亚麻油,主要含有亚麻酸等不饱和脂肪酸,其中含有50%以上的α-亚麻酸。 Linseed oil mainly by the press from flax, flax mainly in the north and northwest, the linseed crush prepared linseed oil, containing primarily linolenic acid and other unsaturated fatty acids, containing more than 50% α- linolenic acid.

人类日常生活必须脂肪酸包括饱和脂肪酸及一价不饱和脂肪酸系列,亚油酸(ω-6系列)和α-亚麻酸系列(ω-3系列),人体自身能够合成饱和脂肪酸及一价不饱和脂肪酸,但不能合成亚油酸和α-亚麻酸,只能从食物中摄取。 Everyday human essential fatty acids include saturated fatty acids and monovalent unsaturated fatty acid series, linoleic acid (ω-6 series) and α- linolenic acid series (ω-3 series), the body itself capable of synthesizing unsaturated fatty acids and monovalent unsaturated fatty acid but we can not synthesize linoleic acid and linolenic acid α- only from food intake. α-亚麻酸具有抑制过敏反应抗炎作用、保护视力、增强智力提高记忆力、抑制衰老、降血脂防止动脉硬化、防止心脑血管病等作用。 α- linolenic acid can inhibit allergic inflammatory effect, protect eyesight, enhance intelligence and improve memory, suppress aging, lowering blood pressure to prevent atherosclerosis and prevent cardiovascular diseases and so on. α-亚麻酸的缺乏会引起生长发育缓慢,严重时可能造成神经性皮炎、高胆固醇血症、脂肪肝、前列腺素代谢紊乱、视觉功能障碍等病症,一旦长期缺乏有可能引起大脑持续性的损害,造成记忆力衰退、老年痴呆症、智力低下等严重后果。 Α- linolenic acid deficiency causes slow growth, severe cases may cause neurodermatitis, hypercholesterolemia, fatty liver, prostaglandin metabolism disorders, visual impairment and other diseases, once a chronic lack of continuity may cause brain damage , resulting in memory loss, severe consequences of Alzheimer's disease, mental retardation and so on. 基于α-亚麻酸的重要作用和人体普遍摄取不足的状况,1993年联合国FAO和WHO建议专项补充α-亚麻酸。 Based on the important role of α- linolenic acid intake and lack of universal human situation, in 1993 the United Nations FAO and WHO recommend special supplement α- linolenic acid. 亚麻油含α-亚麻酸约50%,可作为α-亚麻酸补给源。 Α- linolenic acid linseed oil containing about 50%, as a supply source of α- linolenic acid. 但亚麻油存在一些缺点:气味不佳;不饱和脂肪酸含量较高,易引起氧化酸败;作为食品中添加的油脂,不易混匀,生物利用度不高。 However, linseed oil has some disadvantages: bad odor; high in unsaturated fatty acids, can lead to oxidative rancidity; fat and oil added to food, easy to mix, the bioavailability is not high.

微胶囊技术是一种用成膜材料把固体或液体包覆形成微小粒子的技术,这种技术经过几十年的不断发展,已日趋成熟。 Microencapsulation is a technique for forming a coating material to form a solid or liquid fine particles, this technique after decades of continuous development, has matured. 在制药、食品、农业化学品、香料、饲料添加剂以及日用化学品等工业领域中得到广泛应用。 Widely used in industrial pharmaceutical, food, agricultural chemicals, spices, feed additives and the use of chemicals and the like. 近年来,微胶囊技术在高附加值油脂产品制备领域中是令人关注的热点之一。 In recent years, microencapsulation technology is the focus of concern in the manufacture of high value-added oil products in the field. 油脂被微胶囊化后,可以降低油脂的热敏性、防止光敏性脂溶性成分受到破坏,从而提高油脂制品的营养性、风味稳定性及生物利用度。 After the oil is microencapsulated, you can reduce the heat-sensitive oil, to prevent damage to the photosensitive liposoluble components, thereby improving the nutritional product oils, flavor stability and bioavailability.

文献《亚麻油粉末油脂制备的研究》一文报道了以明胶、阿拉伯胶为主要壁材,采用复合凝聚法原理,对亚麻油进行微胶囊化。 Document "Preparation of linseed oil powder" a paper reported gelatin, gum arabic as wall materials primarily using the principle of complex coacervation method of microencapsulation linseed oil. 制备过程中需要进行化学固化处理,这给产品质量带来很大的影响。 Preparation process requires chemical curing process, which gives the product quality a great deal of influence. 另外,该产品经过较长时间放置后,流动性变差,易出现不同程度结块。 In addition, the product is placed after a longer period, the fluidity is deteriorated, easily blocking varying degrees.

中国专利公开CN1222278C报道了采用阿拉伯胶、麦芽糊精及变性淀粉作为囊材制备α-亚麻酸微胶囊。 Chinese patent CN1222278C discloses reported the use of gum arabic, maltodextrin and modified starch prepared α- linolenic acid as the wall material of microcapsules. 在制备方法中,芯材制备需要在60~70℃条件下加入单甘酯乳化α-亚麻酸,制备囊材品种多。 In the preparation method, the core material needs to be added was prepared α- linolenic acid monoglyceride emulsion at 60 ~ 70 ℃, prepared from a pouch timber varieties.

上述文献及专利中包裹囊材均采用了阿拉伯胶等多种材料,这对产品质量控制是不利的,由于高浓度阿拉伯胶水溶液粘度比较大,给喷雾干燥带来很大的不便;专利CN1222278C温度过高,易引起α-亚麻酸氧化失去活性,而且还加入单甘酯乳化剂。 Wrapping the above references and patents are used capsule material gum arabic and other materials, which is disadvantageous in product quality control, because the high viscosity aqueous gum arabic solution concentration is relatively large, a great deal of inconvenience spray drying; Patent CN1222278C temperature too, can lead to loss of activity of oxidizing α- linolenic acid, but also added monoglyceride emulsifier. 因此需要寻找一种合适单一的材料(其高浓度水溶液粘度低)作为包裹囊材在低温条件下制备出稳定性好、流动性大的高品质亚麻油微胶囊粉末。 It is necessary to find a suitable single material (which is a high concentration of a low viscosity aqueous solution) prepared good stability, high-quality mobility microcapsule powder linseed oil at low temperatures as wrapping the balloon material.

发明内容 SUMMARY

本发明的目的是提供一种亚麻油微胶囊粉末及其制备方法,通过单一的辛烯基琥珀酸淀粉钠作为囊材,在较低温度下对亚麻油进行微胶囊化,解决含有亚麻油的粉体产品的结块、流动性差的问题,从而制备一种稳定性高、流动性好、且能较好保持亚麻油活性的亚麻油微胶囊粉末。 Object of the present invention to provide a method of preparing a powder and linseed oil microcapsules, as the balloon material at a lower temperature of linseed oil microencapsulated by a single starch sodium octenyl succinate, a solution containing linseed oil caking powder products, the problem of poor flowability, thereby preparing a high stability and good fluidity, and can preferably maintained microcapsule powder linseed oil linseed activity.

本发明的技术方案为:一种亚麻油微胶囊粉末,其特征在于:该亚麻油微胶囊粉末由1重量份芯材及0.6~9重量份囊材组成,芯材为亚麻油,囊材为辛烯基琥珀酸淀粉钠,分散于囊材中的亚麻油的平均粒径小于1000nm。 Aspect of the present invention is: one kind of linseed oil microcapsule powder, wherein: the linseed oil from the microcapsule powder 1 part by weight of the core material by weight and 0.6 to 9 parts by capsule material composition, linseed oil core material, the balloon material is a sodium starch octenyl succinate, capsule material dispersed in an average particle size in the linseed oil is less than 1000nm.

本发明的技术特征还在于:分散于囊材辛烯基琥珀酸淀粉钠中的亚麻油平均粒径为100~500nm。 Technical features of the present invention is further characterized by: average particle diameter dispersed in linseed oil, sodium octenyl succinate starch capsule material is from 100 ~ 500nm.

为了进一步提高产品本身的抗氧化能力,防止亚麻油中的不饱和脂肪酸被氧化,增加亚麻油的稳定性,本发明还可根据需要在芯材中加入0.1~0.5重量份维生素E。 In order to further enhance the antioxidant capacity of the product itself, to prevent linseed oil unsaturated fatty acid is oxidized, to increase the stability of the linseed oil, the present invention may also be added 0.1 to 0.5 parts by weight of the core material in vitamin E. necessary

本发明还提供了一种所述亚麻油微胶囊粉末的制备方法,其特征在于该方法按如下步骤进行:1)称取0.6~9重量份辛烯基琥珀酸淀粉钠加入水中,在70~80℃条件下搅拌至辛烯基琥珀酸淀粉钠完全溶解,形成30%~60%的辛烯基琥珀酸淀粉钠水溶液;2)将1)中形成的辛烯基琥珀酸淀粉钠水溶液降温至30~40℃,然后向该溶液中加入1重量份亚麻油,搅拌形成均一的乳液;3)将2)中形成的乳液在500~1500bar压力下经过高压均质机均质循环3~8次,形成亚麻油平均粒径小于1000nm的乳液;4)将3)中形成的乳液进行喷雾干燥制粒,即得到亚麻油微胶囊粉末;或者将3)中形成的乳液进行冷冻干燥,然后将冷冻干燥产品经过粉碎制粒处理,即得到亚麻油微胶囊粉末。 The present invention further provides a method of preparing microcapsules of the one linseed powder, wherein the method proceeds as follows: 1) Weigh 0.6 to 9 parts by weight of starch sodium octenyl succinate were added to water at 70 ~ at 80 ℃ for stirred until starch sodium octenyl succinate completely dissolved to form a 30% to 60% of the starch sodium octenyl succinate solution; 2) cooling the sodium starch octenyl succinate solution 1) formed to 30 ~ 40 ℃, then added to the solution 1 parts by weight linseed oil and stirred to form a uniform emulsion; 3) emulsion 2) formed through a high pressure homogenizer homogenization cycles at 500 ~ 1500bar pressure of 3 to 8 times forming an emulsion of linseed oil is less than the average particle diameter of 1000nm; 4) the emulsion of 3) formed in the spray drying granulation, i.e. linseed obtained microcapsule powder; 3, or the emulsion) to form a freeze-dried, frozen and then dried granulated product after pulverization treatment, to obtain a microcapsule powder linseed oil.

本发明亚麻油微胶囊粉末采用单一的囊材在30~40℃条件成功制备了亚麻油小液滴粒径小于1000nm亚麻油微胶囊,该囊材选用一种被全球批准应用于食品的改性多糖——辛烯基琥珀酸淀粉钠,这类多糖分子量大,在油水界面处形成一层强度很大的薄膜。 The present invention is linseed oil microcapsule powder in a condition of 30 ~ 40 ℃ linseed oil droplets size less than 1000nm linseed oil microcapsules successfully prepared using a single balloon material, the balloon material is selected to be approved in the world used in food modified polysaccharide - sodium octenyl succinate starch, high molecular weight polysaccharides such, form a great strength of the film in a layer at the oil-water interface. 通过本发明制备出的亚麻油微胶囊粉末有效地防止了亚麻油中的不饱和脂肪酸氧化酸败,增加了亚麻油的稳定性,保持亚麻油的活性,掩盖了亚麻油不愉快地气味,提高了亚麻油生物利用度;贮存运输方便,而且易于加入食品和保健品中。 Linseed microcapsule powder prepared by the present invention effectively prevents rancidity of the unsaturated fatty acids in linseed oil, linseed oil increases the stability, maintain the activity of linseed oil, to mask the unpleasant odor of linseed oil, flax increased oil bioavailability; convenient storage and transportation, and easy addition of food and health products.

具体实施方式 detailed description

本发明所提供的亚麻油微胶囊粉末由1重量份芯材及0.6~9重量份囊材组成,芯材为亚麻油,囊材为辛烯基琥珀酸淀粉钠。 Linseed microcapsule powder provided by the present invention, 1 part by weight of the core material by weight and 0.6 to 9 parts by capsule material composition, linseed oil core material, the balloon material is sodium octenyl succinate starch. 芯材是被囊材辛烯基琥珀酸淀粉钠包裹着,辛烯基琥珀酸淀粉钠的亲油端插入芯材亚麻油中,而亲水端指向相反的方向。 The core material is wrapped in the balloon material is starch sodium octenyl succinate, lipophilic ends of sodium octenyl succinate starch core member linseed oil, and the hydrophilic end point in opposite directions. 分散于囊材中的亚麻油平均粒径小于1000nm。 Capsule material dispersed in the linseed oil is less than the average particle diameter of 1000nm.

通过对芯材及囊材的配比优化,及制备工艺的优化,该亚麻油微胶囊中分散于囊材中的亚麻油平均粒径为100~500nm。 By optimizing the ratio of the core material and the balloon, and optimization of the preparation process, the linseed oil in microcapsules dispersed in linseed oil capsule material average particle diameter of 100 ~ 500nm.

本发明亚麻油微胶囊粉末,可根据需要在芯材中加入0.1~0.5重量份维生素E,一是提高产品本身的抗氧化能力,二是进一步防止亚麻油中的不饱和脂肪酸被氧化,增加亚麻油的稳定性。 Linseed microcapsule powder according to the present invention, may be added as desired in the core material of 0.1 to 0.5 parts by weight of vitamin E, one is to improve the oxidation resistance of the product itself, to prevent further two unsaturated fatty acid is oxidized linseed oil, flax increased stability of the oil.

本发明亚麻油微胶囊粉末的制备方法,其特征在于:制备方法由如下步骤组成:1)称取0.6~9重量份辛烯基琥珀酸淀粉钠加入水中,在70~80℃条件下搅拌至辛烯基琥珀酸淀粉钠完全溶解,形成30%~60%的辛烯基琥珀酸淀粉钠水溶液。 Linseed microcapsule powder preparation method of the present invention is characterized in that: prepared by the following steps: 1) Weigh 0.6 to 9 parts by weight of starch sodium octenyl succinate in water was added and stirred until at 70 ~ 80 ℃ starch sodium octenyl succinate completely dissolved, 30% to 60% of the formed sodium starch octenyl succinate solution.

2)将1)中形成的辛烯基琥珀酸淀粉钠水溶液降温至30~40℃,然后向该溶液中加入1重量份亚麻油,搅拌形成均一的乳液。 2) A starch sodium octenyl succinate solution 1) formed was cooled to 30 ~ 40 ℃, then added to the solution 1 parts by weight linseed oil and stirred to form a uniform emulsion.

3)将2)中形成的乳液在500~1500bar压力下经过高压均质机均质循环3~8次,形成亚麻油平均粒径小于1000nm的乳液。 3) the emulsion 2) formed through a high pressure homogenizer homogenization cycles at 500 ~ 1500bar pressure of 3 to 8 times, linseed oil to form an emulsion of average particle size less than 1000nm.

4)将3)中形成的乳液进行喷雾干燥制粒,即得到亚麻油微胶囊粉末;或者将3)中形成的乳液进行冷冻干燥,然后将冷冻干燥产品经过粉碎制粒处理,即得到亚麻油微胶囊粉末。 4) the emulsion of 3) formed in the spray drying granulation, i.e. linseed obtained microcapsule powder; 3, or the emulsion) to form a freeze-dried, freeze-dried product was then crushed granulation process, i.e., linseed oil to give microcapsule powder.

制备方法步骤4)喷雾干燥条件如下:进风温度180~230℃,出风温度40~80℃;冷冻干燥温度为-40~-80℃。 Preparation Step 4) spray-drying conditions were as follows: inlet temperature 180 ~ 230 ℃, outlet temperature 40 ~ 80 ℃; freeze-drying temperature is -40 ~ -80 ℃.

以下列举七个实施例对本发明权利要求范围内作进一步说明:实施例1称取0.6重量份辛烯基琥珀酸淀粉钠加入2重量份水中,在70℃条件下搅拌形成辛烯基琥珀酸淀粉钠水溶液;将该溶液降温至40℃,然后向该溶液中加入1重量份亚麻油,继续搅拌至形成亚麻油初乳;再将该初乳在1500bar压力条件下高压均质3次形成乳白色乳液;最后将该乳白色乳液通过喷雾干燥得到白色亚麻油微胶囊粉末,进风温度为190℃,出风温度为50℃。 Include the following seven embodiments within the scope of the claimed invention will be further described: Example 1 weighed 0.6 parts by weight of starch sodium octenyl succinate were added 2 parts by weight of water, stirred at 70 ℃ for forming starch octenyl succinate aqueous sodium; the solution was cooled to 40 ℃, then this solution was added 1 part by weight of linseed oil, linseed stirring was continued until formation of colostrum; then the colostrum is formed under conditions of pressure 1500bar milky emulsion of a high pressure homogenizer 3 times ; Finally, the milky white emulsion was obtained by spray drying linseed microcapsule powder, inlet air temperature of 190 deg.] C, outlet air temperature of 50 ℃. 通过激光粒度仪测定该乳白色乳液平均粒径为718nm。 Measured by a laser particle sizer of the milky latex of average particle diameter 718nm.

实施例2称取1重量份辛烯基琥珀酸淀粉钠加入3重量份水中,在75℃条件下搅拌形成辛烯基琥珀酸淀粉钠水溶液;将该溶液降温至35℃,然后向该溶液中加入1重量份亚麻油,继续搅拌至形成亚麻油初乳;再将该初乳在800bar压力条件下高压均质4次形成乳白色乳液;最后将该乳白色乳液通过喷雾干燥得到白色亚麻油微胶囊粉末,进风温度为190℃,出风温度为40℃。 Example 2 weighed 1 part by weight of starch sodium octenyl succinate were added 3 parts by weight of water, stirred at 75 deg.] C formed sodium starch octenyl succinate solution; cooling the solution to 35 ℃, then this solution 1 part by weight of linseed oil, stirring is continued until formation of flax colostrum; colostrum was added and the milky emulsion is formed under conditions of high pressure homogenization pressure of 800bar 4; Finally, the milky white emulsion was obtained by spray drying linseed microcapsule powder , 190 deg.] C inlet air temperature, outlet air temperature was 40 ℃. 通过激光粒度仪测定该乳白色乳液平均粒径为602nm。 Measured by a laser particle sizer of the milky latex of average particle diameter 602nm.

实施例3称取4重量份辛烯基琥珀酸淀粉钠加入10重量份水中,在80℃条件下搅拌形成辛烯基琥珀酸淀粉钠水溶液;将该溶液降温至30℃,然后向该溶液中加入1重量份亚麻油和0.1重量份维生素E,继续搅拌至形成亚麻油初乳;再将该初乳在1000bar压力条件下高压均质4次形成乳白色乳液;最后将该乳白色乳液通过喷雾干燥得到白色亚麻油微胶囊粉未,进风温度为200℃,出风温度为60℃。 Example 3 weighed 4 parts by weight of starch sodium octenyl succinate were added 10 parts by weight of water, stirred at 80 ℃ for forming starch sodium octenyl succinate solution; cooling the solution to 30 ℃, then this solution linseed oil and 1 part by weight 0.1 parts by weight of vitamin E, stirring is continued until formation of flax colostrum; colostrum was added and the milky emulsion is formed under conditions of high pressure homogenization pressure of 1000bar 4; Finally, the milky white emulsion was obtained by spray-drying white powder microcapsules linseed oil, inlet air temperature of 200 ℃, the air temperature was 60 ℃. 通过激光粒度仪测定该乳白色乳液平均粒径为448nm。 Measured by a laser particle sizer of the milky latex of average particle diameter 448nm.

实施例4称取6重量份辛烯基琥珀酸淀粉钠加入10重量份水中,在80℃条件下搅拌形成辛烯基琥珀酸淀粉钠水溶液;将该溶液降温至35℃,然后向该溶液中加入1重量份亚麻油和0.5重量份维生素E,继续搅拌至形成亚麻油初乳;再将该初乳在800bar压力条件下高压均质6次形成乳白色乳液;最后将该乳白色乳液通过喷雾干燥得到白色亚麻油微胶囊粉末,进风温度为210℃,出风温度为60℃。 Example 4 6 parts by weight weighed octenyl succinate starch sodium were added 10 parts by weight of water, stirred at 80 ℃ for forming starch sodium octenyl succinate solution; cooling the solution to 35 ℃, then this solution linseed oil and 1 part by weight 0.5 parts by weight of vitamin E, stirring is continued until formation of flax colostrum; colostrum was added and the milky emulsion is formed under conditions of high pressure homogenization pressure of 800bar 6; Finally, the milky white emulsion was obtained by spray-drying white linseed microcapsule powder, inlet air temperature of 210 deg.] C, outlet air temperature was 60 ℃. 通过激光粒度仪测定该乳白色乳液平均粒径为332nm。 Measured by a laser particle sizer of the milky latex of average particle diameter 332nm.

实施例5称取9重量份辛烯基琥珀酸淀粉钠加入20重量份水中,在75℃条件下搅拌形成辛烯基琥珀酸淀粉钠水溶液;将该溶液降温至35℃,然后向该溶液中加入1重量份亚麻油,继续搅拌至形成亚麻油初乳;再将该初乳在500bar压力条件下高压均质8次形成乳白色乳液;最后将该乳白色乳液通过喷雾干燥得到白色亚麻油微胶囊粉末,进风温度为230℃,出风温度为80℃。 Example 9 weighed 5 parts by weight of starch sodium octenyl succinate were added 20 parts by weight of water, stirring to form a starch sodium octenyl succinate solution at 75 deg.] C; the solution was cooled to 35 ℃, then this solution 1 part by weight of linseed oil, stirring is continued until formation of flax colostrum; colostrum was added and the milky emulsion is formed under conditions of high pressure homogenization pressure of 500bar 8; Finally, the milky white emulsion was obtained by spray drying linseed microcapsule powder , 230 deg.] C inlet air temperature, outlet air temperature was 80 ℃. 通过激光粒度仪测定该乳白色乳液平均粒径为204nm。 Measured by a laser particle sizer of the milky latex of average particle diameter 204nm.

实施例6称取9重量份辛烯基琥珀酸淀粉钠加入20重量份水中,在75℃条件下搅拌形成辛烯基琥珀酸淀粉钠水溶液;将该溶液降温至35℃,然后向该溶液中加入1重量份亚麻油,继续搅拌至形成亚麻油初乳;再将该初乳在800bar压力条件下高压均质6次形成乳白色乳液;最后将该乳白色乳液在-80℃冷冻干燥8h得到块状亚麻油微胶囊,最后将该块状亚麻油微胶囊经过研钵碾碎得到亚麻油微胶囊粉末。 Example 9 weighed 6 parts by weight of starch sodium octenyl succinate were added 20 parts by weight of water, stirred at 75 deg.] C is formed starch sodium octenyl succinate solution; cooling the solution to 35 ℃, then this solution 1 part by weight of linseed oil, stirring is continued until formation of flax colostrum; colostrum was added and the milky emulsion is formed under conditions of high pressure homogenization pressure of 800bar 6; the final bulk obtained milky emulsion was freeze-dried at -80 ℃ 8h microcapsules linseed oil, linseed cake and finally the microcapsules through the ground with a mortar to give linseed microcapsule powder. 通过激光粒度仪测定该乳白色乳液平均粒径为138nm。 Measured by a laser particle sizer of the milky latex of average particle diameter 138nm.

实施例7称取4重量份辛烯基琥珀酸淀粉钠加入10重量份水中,在80℃条件下搅拌形成辛烯基琥珀酸淀粉钠水溶液;将该溶液降温至35℃,然后向该溶液中加入1重量份亚麻油,继续搅拌至形成亚麻油初乳;再将该初乳在1000bar压力条件下高压均质6次形成乳白色乳液;最后将该乳白色乳液在-40℃冷冻干燥18h得到块状亚麻油微胶囊,最后将该块状亚麻油微胶囊经过球磨机碾碎得到亚麻油微胶囊粉末。 Example 7 weighed 4 parts by weight of starch sodium octenyl succinate were added 10 parts by weight of water, stirred at 80 ℃ for forming starch sodium octenyl succinate solution; cooling the solution to 35 ℃, then this solution 1 part by weight of linseed oil, stirring is continued until formation of flax colostrum; colostrum was added and the milky emulsion is formed under conditions of high pressure homogenization pressure of 1000bar 6; Finally, the milky emulsion was frozen at -40 ℃ dried to obtain a massive 18h microcapsules linseed oil, linseed cake and finally the microcapsules through a ball mill crushed flax obtained microcapsule powder. 通过激光粒度仪测定该乳白色乳液平均粒径为221nm。 Measured by a laser particle sizer of the milky latex of average particle diameter 221nm.

Claims (4)

  1. 1.一种亚麻油微胶囊粉末,其特征在于:该亚麻油微胶囊粉末由1重量份芯材及0.6~9重量份囊材组成,芯材为亚麻油,囊材为辛烯基琥珀酸淀粉钠,分散于囊材中的亚麻油的平均粒径小于1000nm。 A microcapsule powder linseed oil, characterized in that: the linseed oil from the microcapsule powder 1 part by weight of the core material by weight and 0.6 to 9 parts by capsule material composition, linseed oil core material, the balloon material is octenyl succinate sodium starch glycolate, dispersed in an average particle size in the capsule material linseed oil is less than 1000nm.
  2. 2.按照权利要求1所述的亚麻油微胶囊粉末,其特征在于:分散于囊材辛烯基琥珀酸淀粉钠中的亚麻油平均粒径为100~500nm。 2. Linseed oil according to claim 1 of the microcapsule powder, wherein: the average particle diameter is dispersed in linseed oil, sodium octenyl succinate starch capsule material is from 100 ~ 500nm.
  3. 3.按照权利要求1或2所述的亚麻油微胶囊粉末,其特征在于:在芯材中还含有0.1~0.5重量份的维生素E。 3. Linseed oil according to claim microcapsule powder of claim 1 or 2, characterized in that: the core material further contains 0.1 to 0.5 parts by weight of vitamin E.
  4. 4.一种如权利要求1所述的亚麻油微胶囊粉末制备方法,其特征在于该方法按如下步骤进行:1)将0.6~9重量份的辛烯基琥珀酸淀粉钠加入水中,在70~80℃条件下搅拌至辛烯基琥珀酸淀粉钠完全溶解,形成30%~60%的辛烯基琥珀酸淀粉钠水溶液;2)将1)中形成的辛烯基琥珀酸淀粉钠水溶液降温至30~40℃,然后向该溶液中加入1重量份的亚麻油,搅拌后形成均一的乳液;3)将2)中形成的乳液在500~1500bar压力下经过高压均质机均质循环3~8次,形成亚麻油平均粒径小于1000nm的乳液;4)将3)中形成的乳液进行喷雾干燥制粒,即得到亚麻油微胶囊粉末;或者将3)中形成的乳液进行冷冻干燥,然后将冷冻干燥的产品经过粉碎制粒处理,即得到亚麻油微胶囊粉末。 4. A method of linseed oil microcapsules prepared powder according to claim 1, wherein the method proceeds as follows: 1) 0.6 to 9 parts by weight of starch sodium octenyl succinate were added to water at 70 ~ 80 ℃ under stirring to the starch sodium octenyl succinate completely dissolved to form a 30% to 60% of the starch sodium octenyl succinate solution; 2) a starch sodium octenyl succinate solution cooled 1) formed to 30 ~ 40 ℃, then this solution was added 1 part by weight linseed oil, was stirred to form a uniform emulsion; 3) the emulsion of 2) formed through the high pressure homogenizer under homogenization cycles 3 500 ~ 1500bar pressure ~ 8 times to form an emulsion of linseed oil is less than the average particle diameter of 1000nm; 4) the emulsion of 3) formed in the spray drying granulation, i.e. linseed obtained microcapsule powder; 3, or the emulsion) to form a freeze-dried, the freeze-dried product was then crushed granulation process, i.e. linseed obtained microcapsule powder.
CN 200710063829 2007-02-12 2007-02-12 Linseed oil microcapsule powder and preparation method thereof CN100506282C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 200710063829 CN100506282C (en) 2007-02-12 2007-02-12 Linseed oil microcapsule powder and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 200710063829 CN100506282C (en) 2007-02-12 2007-02-12 Linseed oil microcapsule powder and preparation method thereof

Publications (2)

Publication Number Publication Date
CN101019838A true true CN101019838A (en) 2007-08-22
CN100506282C CN100506282C (en) 2009-07-01

Family

ID=38707765

Family Applications (1)

Application Number Title Priority Date Filing Date
CN 200710063829 CN100506282C (en) 2007-02-12 2007-02-12 Linseed oil microcapsule powder and preparation method thereof

Country Status (1)

Country Link
CN (1) CN100506282C (en)

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101919454A (en) * 2010-08-16 2010-12-22 苏州市佳禾食品工业有限公司 Acid-resistant non-dairy creamer and preparation method thereof
CN102048159A (en) * 2010-11-15 2011-05-11 清华大学 Camellia oil microcapsule powder and preparation method thereof
CN101390588B (en) 2008-11-14 2011-07-27 中国农业大学 Grease microcapsule prepared by high-pressure homogeneous modification rice starch and method thereof
CN102177980A (en) * 2011-04-08 2011-09-14 江苏隆力奇生物科技股份有限公司 Maize germ oil microcapsule powder and preparation method thereof
CN102429215A (en) * 2011-10-24 2012-05-02 陈元涛 Linolenic acid microcapsules and preparation method thereof
CN102716087A (en) * 2012-05-31 2012-10-10 浙江中同科技有限公司 Vitamin powder and preparation method thereof
CN102802436A (en) * 2010-03-29 2012-11-28 弗门尼舍有限公司 Spray-dried crystalline active ingredient
CN102919389A (en) * 2012-10-26 2013-02-13 华南农业大学 Refining method for separating chicken oil by using salt roasted chicken marinade and preparation method for chicken oil powder
CN102934703A (en) * 2012-11-13 2013-02-20 中国食品发酵工业研究院 Flaxseed oil microcapsule and production method thereof
CN103082033A (en) * 2013-02-06 2013-05-08 浙江中同科技有限公司 Instant powdery grease treating starch sodium octenylsuccinate as wall material, and its preparation method
CN103169921A (en) * 2013-03-21 2013-06-26 武汉蜀泰科技有限公司 Production method of zedoary turmeric oil microcapsule
CN103461988A (en) * 2013-07-29 2013-12-25 河北欣奇典生物科技有限公司 High-content alpha-linolenic acid microcapsule and manufacturing method thereof
CN103596453A (en) * 2011-05-30 2014-02-19 林来福医药公司 Health-giving foodstuff containing ethyl esters of fatty acids, namely of linen oil, and method for obtaining the same
CN103990424A (en) * 2014-04-23 2014-08-20 江南大学 Preparation method of straight chain dextrin embedded conjugated linoleic acid microcapsules
CN104012789A (en) * 2014-05-23 2014-09-03 山西省生态畜牧产业管理站 Feed additive for adjusting and controlling beef flavor and preparing method of feed additive
CN104147987A (en) * 2014-08-05 2014-11-19 叶氏化工研发(上海)有限公司 Preparation method for microcapsules coating air-drying film forming material
CN104706621A (en) * 2015-03-19 2015-06-17 国邦医药化工集团有限公司 Marbofloxacin micro-capsule and preparation method thereof
CN104782799A (en) * 2015-05-05 2015-07-22 菏泽大树生物工程科技有限公司 Novel flax oil powder and preparation method thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6953593B2 (en) 2000-02-01 2005-10-11 Lipoprotein Technologies, Inc. Sustained-release microencapsulated delivery system
CN1222278C (en) 2001-05-23 2005-10-12 上海展望集团有限公司 Alpha-linolenic acid microcapsule and its preparing process
DE60320380T2 (en) 2002-02-14 2009-05-20 Dsm Ip Assets B.V. Coenzyme q10 formulations

Cited By (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101390588B (en) 2008-11-14 2011-07-27 中国农业大学 Grease microcapsule prepared by high-pressure homogeneous modification rice starch and method thereof
CN102802436A (en) * 2010-03-29 2012-11-28 弗门尼舍有限公司 Spray-dried crystalline active ingredient
CN106974316A (en) * 2010-03-29 2017-07-25 弗门尼舍有限公司 Spray-dried crystalline active ingredient
CN101919454B (en) 2010-08-16 2013-05-01 苏州市佳禾食品工业有限公司 Acid-resistant non-dairy creamer and preparation method thereof
CN101919454A (en) * 2010-08-16 2010-12-22 苏州市佳禾食品工业有限公司 Acid-resistant non-dairy creamer and preparation method thereof
CN102048159B (en) 2010-11-15 2013-02-13 清华大学 Camellia oil microcapsule powder and preparation method thereof
CN102048159A (en) * 2010-11-15 2011-05-11 清华大学 Camellia oil microcapsule powder and preparation method thereof
CN102177980A (en) * 2011-04-08 2011-09-14 江苏隆力奇生物科技股份有限公司 Maize germ oil microcapsule powder and preparation method thereof
CN103596453A (en) * 2011-05-30 2014-02-19 林来福医药公司 Health-giving foodstuff containing ethyl esters of fatty acids, namely of linen oil, and method for obtaining the same
CN102429215B (en) 2011-10-24 2013-05-01 陈元涛 Linolenic acid microcapsules and preparation method thereof
CN102429215A (en) * 2011-10-24 2012-05-02 陈元涛 Linolenic acid microcapsules and preparation method thereof
CN102716087A (en) * 2012-05-31 2012-10-10 浙江中同科技有限公司 Vitamin powder and preparation method thereof
CN102716087B (en) 2012-05-31 2014-06-11 浙江中同科技有限公司 Vitamin powder and preparation method thereof
CN102919389A (en) * 2012-10-26 2013-02-13 华南农业大学 Refining method for separating chicken oil by using salt roasted chicken marinade and preparation method for chicken oil powder
CN102934703A (en) * 2012-11-13 2013-02-20 中国食品发酵工业研究院 Flaxseed oil microcapsule and production method thereof
CN102934703B (en) * 2012-11-13 2015-07-15 中国食品发酵工业研究院 Flaxseed oil microcapsule and production method thereof
CN103082033B (en) 2013-02-06 2014-07-09 浙江中同科技有限公司 Instant powdery grease treating starch sodium octenylsuccinate as wall material, and its preparation method
CN103082033A (en) * 2013-02-06 2013-05-08 浙江中同科技有限公司 Instant powdery grease treating starch sodium octenylsuccinate as wall material, and its preparation method
CN103169921A (en) * 2013-03-21 2013-06-26 武汉蜀泰科技有限公司 Production method of zedoary turmeric oil microcapsule
CN103169921B (en) * 2013-03-21 2015-12-23 武汉科磁聚园科技有限公司 One kind of Curcuma oil producing microcapsules
CN103461988A (en) * 2013-07-29 2013-12-25 河北欣奇典生物科技有限公司 High-content alpha-linolenic acid microcapsule and manufacturing method thereof
CN103461988B (en) * 2013-07-29 2015-05-13 河北欣奇典生物科技有限公司 High-content alpha-linolenic acid microcapsule and manufacturing method thereof
CN103990424A (en) * 2014-04-23 2014-08-20 江南大学 Preparation method of straight chain dextrin embedded conjugated linoleic acid microcapsules
CN103990424B (en) * 2014-04-23 2016-03-09 江南大学 Embedding one linear dextrins were prepared microcapsule conjugated linoleic acid
CN104012789A (en) * 2014-05-23 2014-09-03 山西省生态畜牧产业管理站 Feed additive for adjusting and controlling beef flavor and preparing method of feed additive
CN104012789B (en) * 2014-05-23 2015-11-25 山西省生态畜牧产业管理站 Regulation beef flavor feed additive and preparation method
CN104147987A (en) * 2014-08-05 2014-11-19 叶氏化工研发(上海)有限公司 Preparation method for microcapsules coating air-drying film forming material
CN104706621A (en) * 2015-03-19 2015-06-17 国邦医药化工集团有限公司 Marbofloxacin micro-capsule and preparation method thereof
CN104706621B (en) * 2015-03-19 2017-08-15 国邦医药化工集团有限公司 One kind of marbofloxacin microcapsule and preparation method
CN104782799A (en) * 2015-05-05 2015-07-22 菏泽大树生物工程科技有限公司 Novel flax oil powder and preparation method thereof

Also Published As

Publication number Publication date Type
CN100506282C (en) 2009-07-01 grant

Similar Documents

Publication Publication Date Title
US6887493B2 (en) Multi component controlled release system for oral care, food products, nutraceutical, and beverages
US5456985A (en) Microcapsules of oily liquid
Sansone et al. Maltodextrin/pectin microparticles by spray drying as carrier for nutraceutical extracts
Fuchs et al. Encapsulation of oil in powder using spray drying and fluidised bed agglomeration
McClements et al. Emulsion‐based delivery systems for lipophilic bioactive components
Kaushik et al. Microencapsulation of omega-3 fatty acids: A review of microencapsulation and characterization methods
US20100173002A1 (en) Microcapsules with improved shells
US4867986A (en) Dry stabilized microemulsified omega-three acid-containing oils
Davidov-Pardo et al. Resveratrol encapsulation: designing delivery systems to overcome solubility, stability and bioavailability issues
CN101125133A (en) Unsaturated fatty acid microcapsule preparing technology and application
JP2003300870A (en) Ubiquinone-containing water-soluble composition
US20050106272A1 (en) Co-beadlet of dha and rosemary and methods of use
Wang et al. Optimisation of the microencapsulation of tuna oil in gelatin–sodium hexametaphosphate using complex coacervation
Goula et al. A method for pomegranate seed application in food industries: seed oil encapsulation
Yu et al. Development of a food-grade organogel with high bioaccessibility and loading of curcuminoids
Chen et al. Co-encapsulation of fish oil with phytosterol esters and limonene by milk proteins
CN101669920A (en) Strong anti-oxidation DHA microcapsule and preparation method thereof
US4194013A (en) Methionine-containing microgranulates and method of manufacture
Tavernier et al. Food-grade particles for emulsion stabilization
Cortés-Rojas et al. Encapsulation of eugenol rich clove extract in solid lipid carriers
EP1300394A1 (en) Method for the production of a water-dispersible formulation containing carotenoids
JP2009084224A (en) Microcapsule and method for producing the same
CN101269310A (en) Method for preparing cold water dispersion type microcapsule powder
CN101444495A (en) Vitamin E microcapsule preparation method
JPH07101882A (en) Preparation containing water-soluble hemicellulose

Legal Events

Date Code Title Description
C06 Publication
C10 Entry into substantive examination
C14 Grant of patent or utility model
CF01