CN101658633A - Method for extracting functional components from raw materials with effects of clearing kidney, removing toxin and protecting kidney - Google Patents
Method for extracting functional components from raw materials with effects of clearing kidney, removing toxin and protecting kidney Download PDFInfo
- Publication number
- CN101658633A CN101658633A CN200910073001A CN200910073001A CN101658633A CN 101658633 A CN101658633 A CN 101658633A CN 200910073001 A CN200910073001 A CN 200910073001A CN 200910073001 A CN200910073001 A CN 200910073001A CN 101658633 A CN101658633 A CN 101658633A
- Authority
- CN
- China
- Prior art keywords
- extract
- kidney
- raw material
- extraction
- filtrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses a method for extracting functional components, in particular to an extract which takes palmleaf raspberry fruit, oyster shell, barbary wolfberry fruit, rhizome polygonati and chrysanthemum as raw materials, is obtained by using the method for extraction, and has the effects of clearing kidney, removing toxin, protecting kidney and regulating viscera. The extraction method comprises the proportion and the content of the ingredients of the raw materials and the extraction method of the functional components.
Description
Technical field
The present invention relates to a kind of method for extracting functional components, particularly to be raw material extract the extract that obtains through technology of the present invention has clearly that the kidney toxin expelling has the protection kidney concurrently and regulates the equilibrated effect of internal organs with Fructus Rubi, Concha Ostreae, Fructus Lycii, Rhizoma Polygonati, Flos Chrysanthemi.
Technical background
Kidney is the vitals of human body, its basic function is to generate urine, so as to removing interior metabolism product and some refuse, poisonous substance, keep moisture content and other utilities through heavy absorption function simultaneously, as glucose, protein, aminoacid, sodium ion, potassium ion, sodium bicarbonate etc., to regulate water, electrolyte balance and to safeguard acid-base balance.Kidney also has endocrine function simultaneously, generates feritin, erythropoietin, activity of vitamin d3, prostaglandin, kassinin kinin etc., is again the degraded place of body part endocrine hormone and the target organ of kidney pheromone.These functions of kidney have guaranteed the stable of organismic internal environment, and metabolism is normally carried out.
Modern society is owing to environmental pollution, high-tech radiation, chemical substance increase, rhythm of life is accelerated, pressure is excessive and diet is plump, take medicine or the like reason for a long time, all make people's renal function overload operation, cause kidney cell stasis of blood poison accumulation functionality to descend, the functions of expelling toxin of kidney descends, and the toxin of kidney accumulation in the course of time is more and more.Kidney resembles one and is stained with smeary sponge, no matter how to mend, also be difficult to absorb, and detoxicating not, good again medicine is mended to be entered yet.Meanwhile, we have a meal every day, contain remaining toxin such as a large amount of pesticide, chemical fertilizer in the fruit, vegetable, also contain automobile, poisonous fume that commercial production gave off in the air of breathing.In addition, in order to treat disease, people take a large amount of medicines often, contain much the toxin that can not be absorbed by the body, mediate in the medicine.After these toxin enter human body, decompose, excrete through liver, kidney two big toxin expelling organs.Wherein kidney excretes toxin by producing the urine mode, and some fail to be trapped on the capillary of kidney with refuse, toxin that urine is discharged, and accumulating over a long period forms the taupe crystal deposition, forms kidney poison and kidney dirt.
Kidney poison, kidney dirt is secular to cause renal function to go down in the intravital enrichment of people, and the glomerule fibrosis finally causes the partial loss of function of kidney, even can cause the kidney necrosis, finally leads to serious consequence.Therefore effectively getting rid of kidney dirt that kidney forms for a long time, to remove the kidney poison be to make the restorative basis of kidney, and the kidney dirt in the dimension kidney, kidney poison are removed could further repair glomerule after external, the kidney invigorating recovers renal function.
Extracting method of the present invention is to utilize special extracting mode to extract functional component from the raw material of Chinese medicine of several integration of edible and medicinal herbs to make its functional component can reach best proportion compatibility active component can intactly be preserved.The unclear kidney of kidney poison, kidney dirt is good restore funcitons just, nutrient substance can not enter kidney and effectively provide nutrition for kidney, therefore remove the kidney poison, the kidney dirt is the beginning of treatment kidney disease, the present invention is significant to the treatment of renal disease patient especially diabetic nephropathy patient.
Summary of the invention
The objective of the invention is to; adopt and to adopt that water is carried, alcohol extraction is extracted after the lyophilizing after the ultrasonic Treatment respectively; extract functional component and make capsule preparations from medicine food homologous raw materials Fructus Rubi, Concha Ostreae, Rhizoma Polygonati, Fructus Lycii, Flos Chrysanthemi, said preparation has effects such as the kidney of removing dirt, protection kidney, the kidney invigorating, adjusting internal organs balance.
The present invention is achieved in that
Composition and ratio (weight ratio)
Fructus Rubi: Concha Ostreae: Rhizoma Polygonati 4～5: 2～5: 1～3, Fructus Lycii: Flos Chrysanthemi 5～7: 3～5
The specific embodiment
1. the extracting method of Fructus Rubi, Concha Ostreae, Rhizoma Polygonati: Fructus Rubi, Concha Ostreae, Rhizoma Polygonati are mixed in proportion the back and pulverize 20～50 orders, carrying out lyophilization by freeze-drier handles, raw material after the lyophilizing processing is carried out ultrasonic Treatment 5～10min, and the raw material after the ultrasonic Treatment drops into and carries out in the extraction pot extracting the first time.Extract 5～10 times the water that adds raw material weight for the first time, extraction time is 1～4 hour, and extracting temperature is 50～90 ℃, gets filtrate.Extract for the second time the water extraction 1～3 hour that continues to add 5～10 times of weight in the raw material after filtering, extracting temperature is 50～90 ℃, gets filtrate.Extract for the third time and think to add in the raw material 3～8 times water, extracted 1～2 hour, the extraction temperature is 50～90 ℃, gets filtrate.The filtrate that merges three extractions makes it pass through macroporous resin chromatographic column removing impurities, and dusting after the filtrate after handling is concentrated obtains Fructus Rubi, Concha Ostreae, Rhizoma Polygonati mixing water extracts.Continue 5～8 times alcoholic solution of adding 75～95%, extract each the extraction 1.5～3 hours 2～3 times, the filtrate of united extraction, be concentrated into extractum and add 1 of 100～300 times of weight of fluid extract again, after the ethylene glycol of 2-propylene glycol and 100～200 times of weight of fluid extract fully dissolves, the chitosan magnetic force that adds 10～20 times of weight of fluid extract stirs 20～30min, makes stand-by solution; Dispose the sodium tripolyphosphate solution of 10mg/ml then, after the high-speed stirred of 10000r/min, drip in the stand-by solution; At last, evaporating in fume hood does not have the alcohol flavor, and vacuum drying is to powder.Water carried with ethanol extract mix, make extract.
2. Fructus Lycii Flos Chrysanthemi extract preparation method: Fructus Lycii, Flos Chrysanthemi be proportionally with its mixing, mix back ultrasonic Treatment 5min after, drop into extraction pot, extract three times.Extract for the first time amount of water and be heavy 5～15 times of raw material, extracted 3～5 hours, extracting temperature is 50～90 ℃, and the extraction after-filtration is got filtrate.Extract the water that adds 5～10 times of raw material weights in extraction pot for the second time, extract after 2～3 hours, extracting temperature is 50～90 ℃, gets filtrate continuing to employ.Extract for the third time, add the water of 3～5 times of weight of raw material weight in extraction pot, extracted 1～3 hour, extracting temperature is 50～90 ℃.The filtrate that merges three extractions makes filtrate remove impurity by the chromatographic column that punches, and concentrates, and dusts.
With 1,2 twice system extract according to 1: 4～1: 2 mixed evenly the extract of system have clearly that the kidney toxin expelling has the protection kidney concurrently and regulates the equilibrated effect of internal organs.
Claims (3)
1. method for extracting functional components, particularly to be raw material extract the extract that obtains through technology of the present invention has clearly that the kidney toxin expelling has the protection kidney concurrently and regulates the equilibrated effect of internal organs with Fructus Rubi, Concha Ostreae, Fructus Lycii, Rhizoma Polygonati, Flos Chrysanthemi.Needed raw material composition and ratio (weight ratio): Fructus Rubi: Concha Ostreae: Rhizoma Polygonati 4～5: 2～5: 1～3, Fructus Lycii: Flos Chrysanthemi 5～7: 3～5.
2. according to the requirement of claim 1, the extracting method of raw material with effect that kidney toxin expelling clearly has the effect of protection kidney concurrently is as follows:
(1) extracting method of Fructus Rubi, Concha Ostreae, Rhizoma Polygonati: Fructus Rubi, Concha Ostreae, Rhizoma Polygonati are mixed in proportion the back and pulverize 20～50 orders, carrying out lyophilization by freeze-drier handles, raw material after the lyophilizing processing is carried out ultrasonic Treatment 5～10min, and the raw material after the ultrasonic Treatment drops into and carries out in the extraction pot extracting the first time.Extract 5～10 times the water that adds raw material weight for the first time, extraction time is 1～4 hour, and extracting temperature is 50～90 ℃, leaches after the extraction and gets filtrate.Extract for the second time the water extraction 1～3 hour that continues to add 5～10 times of weight in the raw material after filtering, extracting temperature is 50～90 ℃, waits to leach and gets filtrate.Extract for the third time and think to add in the raw material 3～8 times water, extracted 1～2 hour, the extraction temperature is 50～90 ℃, gets filtrate after the extraction.The filtrate that merges three extractions makes it pass through macroporous resin chromatographic column removing impurities, and dusting after the filtrate after handling is concentrated obtains Fructus Rubi, Concha Ostreae, Rhizoma Polygonati mixing water extracts.Continue 5～8 times alcoholic solution of adding 75～95%, extract each the extraction 1.5～3 hours 2～3 times, the filtrate of united extraction, be concentrated into extractum and add 1 of 100～300 times of weight of fluid extract again, after the ethylene glycol of 2-propylene glycol and 100～200 times of weight of fluid extract fully dissolves, the chitosan magnetic force that adds 10～20 times of weight of fluid extract stirs 20～30min, makes stand-by solution; Dispose the sodium tripolyphosphate solution of 10mg/ml then, after the high-speed stirred of 10000r/min, drip in the stand-by solution; At last, evaporating in fume hood does not have the alcohol flavor, and vacuum drying makes extract to powder.
(2) Fructus Lycii Flos Chrysanthemi extract preparation method: Fructus Lycii, Flos Chrysanthemi behind ultrasonic Treatment 3～5min, drop into extraction pot proportionally with its mixing after mixing, and extract three times.Extract for the first time amount of water and be heavy 5～15 times of raw material, extracted 3～5 hours, extracting temperature is 50～90 ℃, and the extraction after-filtration is got filtrate.Extract the water that adds 5～10 times of raw material weights in extraction pot for the second time, extract after 2～3 hours, extracting temperature is 50～90 ℃, gets filtrate continuing to employ.Extract for the third time, add the water of 3～5 times of weight of raw material weight in extraction pot, extracted 1～3 hour, extracting temperature is 50～90 ℃.The filtrate that merges three extractions makes filtrate pass through the macroporous resin chromatographic column and removes impurity, concentrates, and dusts.
3. according to the described a kind of raw material method for extracting functional components that kidney toxin expelling clearly protects the kidney effect that has of claim 2, with (1) (2) twice system extract even according to 1: 4～1: 2 mixed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910073001A CN101658633A (en) | 2009-09-29 | 2009-09-29 | Method for extracting functional components from raw materials with effects of clearing kidney, removing toxin and protecting kidney |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910073001A CN101658633A (en) | 2009-09-29 | 2009-09-29 | Method for extracting functional components from raw materials with effects of clearing kidney, removing toxin and protecting kidney |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101658633A true CN101658633A (en) | 2010-03-03 |
Family
ID=41787033
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200910073001A Pending CN101658633A (en) | 2009-09-29 | 2009-09-29 | Method for extracting functional components from raw materials with effects of clearing kidney, removing toxin and protecting kidney |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101658633A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104887713A (en) * | 2015-06-23 | 2015-09-09 | 广西北部湾海皇生物科技有限公司 | Preparing method of oyster active extract having functions of producing sperm to tonify the kidney and improving sexual function |
| CN105505711A (en) * | 2016-01-29 | 2016-04-20 | 孙月 | Health-care wine used for dispelling toxoplasma gondii and preparation method thereof |
| CN107874053A (en) * | 2017-11-14 | 2018-04-06 | 重庆市中药研究院 | One kind has anti-oxidant anti-radiation effect cola, preparation method and applications |
| CN110301636A (en) * | 2018-11-05 | 2019-10-08 | 解中胜 | Dual-purpose of drug and food powder with health care function, preparation method and applications |
| CN112544990A (en) * | 2020-12-23 | 2021-03-26 | 汤臣倍健股份有限公司 | Composition with reproductive system improving effect and application thereof |
-
2009
- 2009-09-29 CN CN200910073001A patent/CN101658633A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104887713A (en) * | 2015-06-23 | 2015-09-09 | 广西北部湾海皇生物科技有限公司 | Preparing method of oyster active extract having functions of producing sperm to tonify the kidney and improving sexual function |
| CN105505711A (en) * | 2016-01-29 | 2016-04-20 | 孙月 | Health-care wine used for dispelling toxoplasma gondii and preparation method thereof |
| CN107874053A (en) * | 2017-11-14 | 2018-04-06 | 重庆市中药研究院 | One kind has anti-oxidant anti-radiation effect cola, preparation method and applications |
| CN110301636A (en) * | 2018-11-05 | 2019-10-08 | 解中胜 | Dual-purpose of drug and food powder with health care function, preparation method and applications |
| CN112544990A (en) * | 2020-12-23 | 2021-03-26 | 汤臣倍健股份有限公司 | Composition with reproductive system improving effect and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106667837A (en) | Camellia oleifera component based body lotion and preparation method thereof | |
| CN102293285A (en) | Health-preserving liver-protecting tea and preparation method thereof | |
| CN105125649A (en) | Ages-degrading agent and use thereof | |
| CN105079046A (en) | Whole ganoderma lucidum anti-tumor soft capsules and preparation method thereof | |
| CN103750483B (en) | Dendrobium officinale solid beverage and preparation method thereof | |
| CN101658633A (en) | Method for extracting functional components from raw materials with effects of clearing kidney, removing toxin and protecting kidney | |
| CN104189140B (en) | Photinia serrulata procyanidine as well as preparation method and application thereof | |
| CN106418111A (en) | Antioxidant extract derived from garlic stalks and preparation method thereof | |
| CN101857526A (en) | Method for preparing galactitol or galactitol extract from cistanche or waste residue liquid of cistanche glycoside extraction and application of galactitol and galactitol extract | |
| CN103750295A (en) | Plant polyphenol composition having blood fat reducing function, and preparation method thereof | |
| CN102872195B (en) | A kind of preparation method and application thereof of Chinese cassia tree total polyphenols extract | |
| CN105815440A (en) | Common tulip flower extract-containing fruit and vegetable fresh-keeping agent and preparation method thereof | |
| CN101843311A (en) | Method for preparing hippophae rhamnoides seed micro powder capsules | |
| CN106924304A (en) | The extracting method of Sweet tea active ingredient | |
| CN105533686A (en) | Pomegranate seed powder medicinal granules | |
| CN102872198A (en) | Liver protection capsule and preparation method thereof | |
| CN104522794B (en) | Antrodia camphorata detoxifying beverage and preparation method thereof | |
| CN102614253B (en) | Composition for nourishing and protecting liver and application of composition | |
| CN105876036A (en) | Blood sugar reducing effervescent tablet herbal tea and preparation method thereof | |
| CN104547022A (en) | Traditional Chinese medicinal composition capable of clearing heat, moistening lung, relieving sore throat and detoxifying | |
| CN111821325A (en) | Application of photorhaponticum flower extract | |
| CN103315360B (en) | Radix cynanchi bungei granule and preparation method thereof | |
| CN101837063B (en) | Lipid-lowering and weight-reducing buccal tablets | |
| CN107335022A (en) | A kind of compound zedoary bark of eucommia anti-cervical cancer oral liquid and its preparation technology | |
| CN105475581A (en) | Hibiscus sabdariffa healthcare tea bag and preparing method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| DD01 | Delivery of document by public notice |
Addressee: Ma Hongda Document name: Notification of before Expiration of Request of Examination as to Substance |
|
| DD01 | Delivery of document by public notice |
Addressee: Ma Hongda Document name: Notification that Application Deemed to be Withdrawn |
|
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20100303 |